Datasets:
gowitheflow
/
parallel-talks-deduplicated

Dataset card Data Studio Files
xet
 Community
1
english
stringlengths
2
3.06k
non_english
stringlengths
1
2.84k
language
stringclasses
52 values
You know what the answer was?
Vous savez la réponse ?
en-fr
Zero, not a single one.
ศูนย์ ไม่มีแม้แต่ลูกเดียว
en-th
Now why is that?
Γιατί όμως;
en-el
Is it because their weapons weren't accurate?
Est-ce parce que leurs armes n’étaient pas précises ?
en-fr
Oh no, they were brilliantly accurate.
Åh nej, de var briljant precisa.
en-sv
They could have destroyed this little thing right here from 25,000 ft.
25.000 fıtten bu küçücük şeyi yok edebilirlerdi.
en-tr
The issue was they didn't know where the Scud launchers were.
Masalahnya adalah mereka tidak tahu di mana lokasi pelontar Scud.
en-id
The problem with bombs and pickle barrels is not getting the bomb inside the pickle barrel, it's knowing how to find the pickle barrel.
爆弾と漬物桶の問題で難しいのは 爆弾を桶に入れることではなく 漬物桶をどうやって見つけるかということなのです
en-ja
That's always been the harder problem when it comes to fighting wars.
To je vždycky ten těžší problém, když dojde na vyhrávání válek.
en-cs
Or take the battle in Afghanistan.
או קחו לדוגמה את אפגניסטאן.
en-he
What is the signature weapon of the CIA's war in Northwest Pakistan?
Яка ключова зброя ЦРУ у війні в Північному Пакистані?
en-uk
It's the drone. What is the drone?
Тоа е безпилотното летало.
en-mk
Well it is the grandson of the Norden Mark 15 bombsight.
아마 드론은 M-15 노든 폭격조준경의 손자 쯤 되겠군요
en-ko
It is this weapon of devastating accuracy and precision.
C’est cette arme d’une précision dévastatrice.
en-fr
And over the course of the last six years in Northwest Pakistan, the CIA has flown hundreds of drone missiles, and it's used those drones to kill 2,000 suspected Pakistani and Taliban militants.
過去６年 北西パキスタンで CIAは何百というドローンミサイルを発射し パキスタンやタリバンの 戦闘員と疑わしき ２千人を殺しました
en-ja
Now what is the accuracy of those drones?
那這些無人駕駛的飛機準確度有多高呢？
en-zh-tw
Well it's extraordinary.
Extrem de precise.
en-ro
We think we're now at 95 percent accuracy when it comes to drone strikes.
Nous pensons être à 95% de précision lors des attaques des drones.
en-fr-ca
95 percent of the people we kill need to be killed, right?
95 posto ljudi koje smo ubili, bilo je potrebno ubiti, da?
en-sr
That is one of the most extraordinary records in the history of modern warfare.
Това е едно от най-невероятните постижения на съвременното военно дело.
en-bg
But do you know what the crucial thing is?
Maar weet je wat het cruciale eraan is?
en-nl
In that exact same period that we've been using these drones with devastating accuracy, the number of attacks, of suicide attacks and terrorist attacks, against American forces in Afghanistan has increased tenfold.
U tom istom periodu dok smo koristili bespilotne letelice sa razornom preciznošću, broj napada, samoubilačkih i terorističkih napada, protiv američkih snaga u Avganistanu se udesetostručio.
en-sr
As we have gotten more and more efficient in killing them, they have become angrier and angrier and more and more motivated to kill us.
როდესაც ჩვენ სულ უფრო ეფექტურები ვხდებოდით მათ დახოვცაში ისინი სულ უფრო ბრაზდებოდნენ და უფრო მოტივირებულები ხდებოდნენ ჩვენს დასახოცად.
en-ka
I have not described to you a success story.
Я розказав вам не історію успіху,
en-uk
I've described to you the opposite of a success story.
Descrevi-vos o oposto de uma história de sucesso.
en-pt
And this is the problem with our infatuation with the things we make.
Och det är detta som är problemet med vår blinda förälskelse i de saker vi tillverkar.
en-sv
We think the things we make can solve our problems, but our problems are much more complex than that.
Myślimy, że urządzenia rozwiążą nam problemy, ale te problemy są o wiele bardziej złożone.
en-pl
The issue isn't the accuracy of the bombs you have, it's how you use the bombs you have, and more importantly, whether you ought to use bombs at all.
Le problème n’est pas la précision des bombes, c’est comment on utilise les bombes qu’on a, et encore plus important, s’il faut vraiment utiliser les bombes.
en-fr
There's a postscript to the Norden story of Carl Norden and his fabulous bombsight.
І ось постскриптум до цієї історії про Карла Нордена і його легендарний приціл для бомбометання.
en-uk
And that is, on August 6, 1945, a B-29 bomber called the Enola Gay flew over Japan and, using a Norden bombsight, dropped a very large thermonuclear device on the city of Hiroshima.
Și anume, pe 6 august 1945, un bombardier B-29, Enola Gay, a zburat deasupra Japoniei și folosind un vizor Norden a lansat o bombă termonucleară imensă peste Hiroshima.
en-ro
And as was typical with the Norden bombsight, the bomb actually missed its target by 800 ft.
Co typowe dla celownika Nordena, bomba chybiła celu o 250 m.
en-pl
But of course, it didn't matter.
Αλλά φυσικά, δεν είχε σημασία.
en-el
And that's the greatest irony of all when it comes to the Norden bombsight.
Και αυτή είναι η μεγαλύτερη ειρωνεία απ' όλες όσον αφορά τον κατευθυντή Νόρντεν.
en-el
the air force's 1.5 billion dollar bombsight was used to drop its three billion dollar bomb, which didn't need a bombsight at all.
בכוונת שעלתה לחיל האויר 1.5 מיליארד דולר השתמשו כדי להטיל את הפצצה שעלתה שלושה מיליארד דולר, שכלל לא היתה צריכה כוונת.
en-he
Meanwhile, back in New York, no one told Carl Norden that his bombsight was used over Hiroshima.
في تلك الاثناء في نيويورك لم يخبر احد كارل نوردن ان موجه القنابل خاصته تم استخدامه لقصف هوريشيما
en-ar
He was a committed Christian.
Anh là một người sùng đạo Thiên Chúa giáo.
en-vi
He thought he had designed something that would reduce the toll of suffering in war.
Тој мислел дека направил нешто што ќе го намали страдањето во војна.
en-mk
It would have broken his heart.
זה היה שובר את ליבו.
en-he
I moved to Boston 10 years ago from Chicago, with an interest in cancer and in chemistry.
Przeprowadziłem się do Chicago z Bostonu 10 lat temu, zainteresowany nowotworami i chemią.
en-pl
You might know that chemistry is the science of making molecules or, to my taste, new drugs for cancer.
化學是一項製造分子的科學＝ 或者對我而言，對抗癌症的新興藥劑。
en-zh-tw
And you might also know that, for science and medicine, Boston is a bit of a candy store.
Možda takođe znate da je, što se nauke i medicine tiče, Boston neka vrsta poslastičarnice.
en-sr
You can't roll a stop sign in Cambridge without hitting a graduate student.
In Cambridge kun je niet optrekken aan het stoplicht zonder een masterstudent omver te rijden.
en-nl
The bar is called the Miracle of Science.
Бар називається Дзеркало Науки.
en-uk
The billboards say "Lab Space Available."
Billboardy mówią "Laboratium kosmiczne dostępne".
en-pl
And it's fair to say that in these 10 years, we've witnessed absolutely the start of a scientific revolution -- that of genome medicine.
さて この10年の間 ゲノム医学という科学的革命が 始まったと言っても過言ではないでしょう
en-ja
We know more about the patients that enter our clinic now than ever before.
que entran en nuestra clínica. Y somos capaces, finalmente, de responder la pregunta
en-es
And we're able, finally, to answer the question that's been so pressing for so many years: Why do I have cancer?
яке було таким актуальним багато років: чому у мене рак?
en-uk
This information is also pretty staggering.
Тази информация също е доста потресаваща.
en-bg
You might know that, so far, in just the dawn of this revolution, we know that there are perhaps 40,000 unique mutations affecting more than 10,000 genes, and that there are 500 of these genes that are bona-fide drivers, causes of cancer.
Poate știți asta, până în prezent doar în zorii acestei revoluții, știm că sunt poate 40,000 de mutații unice care afectează mai mult de 10, 000 de gene, și că sunt 500 din aceste gene care sunt conducători clari, pentru cauzele cancerului.
en-ro
Yet comparatively, we have about a dozen targeted medications.
Tačiau palyginimui, mes turime apie tuziną tikslinių vaistų.
en-lt
And this inadequacy of cancer medicine really hit home when my father was diagnosed with pancreatic cancer.
และชนิดของยาที่มีน้อยไม่เพียงพอของยามะเร็งเหล่านี้ ผมรู้สึกได้อย่างจริงจัง เมื่อพ่อผมได้รับการวินัจฉัยว่า เป็นมะเร็งตับอ่อน
en-th
We didn't fly him to Boston.
Mes nepervežėme jo į Bostoną.
en-lt
We didn't sequence his genome.
Nismo sekvencionirali njegov genom.
en-sr
It's been known for decades what causes this malignancy.
Denn seit Jahrzehnten sind die Auslöser bekannt –
en-de
It's three proteins: ras, myc, p53.
Это три белка — Ras, Myc и P53.
en-ru
This is old information we've known since about the 80s, yet there's no medicine I can prescribe to a patient with this or any of the numerous solid tumors caused by these three ...
اطلاعات قدیمی که ما از دهد 80 آنها را میدانیم هنوز داروئی وجود ندارد که من بتونم به یک بیمار با این نوع تومور و یا هر تومور جامد بزرگی که با این سه پروتئین ایجاد شده، تجویز کنم. هنوز داروئی وجود ندارد که من بتونم به یک بیمار با این نوع تومور و یا هر تومور جامد بزرگی که با این سه پروتئین ایجاد شده، تجویز کنم. هنوز داروئ...
en-fa
Horsemen of the Apocalypse that is cancer.
של האפוקליפסה שהיא סרטן.
en-he
There's no ras, no myc, no p53 drug.
ما من عقارٍ لبروتين  Ras ، ولا لـ MIC ، ولا لـ  P53 .
en-ar
And you might fairly ask: Why is that?
E vocês podem perguntar, com razão: por quê?
en-pt-br
And the very unsatisfying yet scientific answer is: it's too hard.
儘管這樣的答案可能令人失望，但是卻是事實： 太難了。
en-zh-tw
That for whatever reason, these three proteins have entered a space, in the language of our field, that's called the undruggable genome -- which is like calling a computer unsurfable or the Moon unwalkable.
Така че по някаква причина, тези три протеини навлязоха в езика на нашата област наречен нелечимия геном -- което е като да наречете компютър неуправляем или Луната непроходима.
en-bg
It's a horrible term of trade.
To je užasan naziv struke.
en-hr
But what it means is that we've failed to identify a greasy pocket in these proteins, into which we, like molecular locksmiths, can fashion an active, small, organic molecule or drug substance.
แต่ความหมายที่แท้จริงของมันคือ เราล้มเหลวที่จะหาตำแหน่งบนโปรตีนเหล่านี้ ก็คงเหมือนกับช่างทำกุญแจ คือเราไม่สามารถสร้างโมเลกุลที่จะไปจับได้พอดีกับโปรตีน เหมือนกุญแจเข้าได้พอดีกับแม่กุญแจ รวมไปถึงเราไม่พบยาที่ทำได้
en-th
Now, as I was training in clinical medicine and hematology and oncology and stem-cell transplantation, what we had instead, cascading through the regulatory network at the FDA, were these substances: arsenic, thalidomide, and this chemical derivative of nitrogen mustard gas.
當我在接受臨床醫學， 血液學，腫瘤學 和干細胞移植的培訓時, 我們反而有的是， 食品藥品管理局地管理網絡上充斥著的 是這些成份-- 砷，鎮靜劑, 還有氮介子氣 的化學衍生物。
en-zh-tw
And this is the 21st century.
I to jest XXI wiek.
en-pl
And so, I guess you'd say, dissatisfied with the performance and quality of these medicines, I went back to school, in chemistry, with the idea that perhaps by learning the trade of discovery chemistry and approaching it in the context of this brave new world of the open source, the crowd source, the collaborative netw...
그래서, 이 제약분야의 수행과 질에 만족하지 않아 저는 화학전공으로 다시 학교로 돌아갔는데 발견 화학의 교역을 학습하여 그것을 오픈소스의, 크라우드 소스의 학문계이내에 우리가 액세스가있는 그 협동적인 네트워크로 우리 환자들에게 강력하고 대상을 겨냥한 치료를 제공할 이 대담한 새로운 세계의 상황에 접근하려는 아이디어를 지니고 있습니다
en-ko
And so, please consider this a work in progress, but I'd like to tell you today a story about a very rare cancer called midline carcinoma, about the undruggable protein target that causes this cancer, called BRD4, and about a molecule developed at my lab at Dana-Farber Cancer Institute, called JQ1, which we affectionat...
Per favore, considerate questo come un lavoro in corso, vorrei però raccontarvi oggi la storia di un cancro molto raro chiamato carcinoma della linea mediana, della proteina bersaglio, la proteina "undruggable" che causa questo cancro, chiamata BRD4, e di una molecola, sviluppata nel mio laboratorio all'istituto sul ca...
en-it
Now, BRD4 is an interesting protein.
자 BRD4는 흥미로운 단백질입니다
en-ko
You might ask: with all the things cancer's trying to do to kill our patient, how does it remember it's cancer?
癌は様々な方法で患者の体を 蝕もうとしますが どうやって自分が癌だと 記憶しているのでしょうか
en-ja
When it winds up its genome, divides into two cells and unwinds again, why does it not turn into an eye, into a liver, as it has all the genes necessary to do this?
分裂成2個細胞再鬆開， 為甚麼它沒有變成一隻眼或者是一個肝臟， 儘管它所擁有的基因完全可以做到這些？
en-zh-tw
It remembers that it's cancer.
Het heeft onthouden dat het kanker is.
en-nl
And the reason is that cancer, like every cell in the body, places little molecular bookmarks, little Post-it notes, that remind the cell, "I'm cancer; I should keep growing."
그 이유는 그 암은, 신체내부의 다른 모든 세포와 같이, 그 세포에게 "나는 암이야; 나는 계속 자라나야해" 라는 작은 분자 책갈피를, 작은 포스트잇(한쪽 끝에 특수 접착제를 칠한 부전지)을 배치합니다
en-ko
And those Post-it notes involve this and other proteins of its class -- so-called bromodomains.
Và những miếng dán nhắc nhở đó tham gia vào việc protein này và các protein khác cùng loại -- gọi là brodomain.
en-vi
So we developed an idea, a rationale, that perhaps if we made a molecule that prevented the Post-it note from sticking by entering into the little pocket at the base of this spinning protein, then maybe we could convince cancer cells, certainly those addicted to this BRD4 protein, that they're not cancer.
私達は次のように考えました― このタンパク質にある 小さなポケットにはまり込む分子を作り この「しおり」の結合を 防ぐことができれば BRD4依存性の癌細胞に 癌ではないと思わせることができる と考えたのです 癌ではないと思わせることができる と考えたのです
en-ja
And so we started to work on this problem.
我們對這個問題展開工作，
en-zh-tw
We developed libraries of compounds and eventually arrived at this and similar substances called JQ1.
Razvili smo knjižnice spojeva i s vremenom došli do ove i sličnih supstanci nazvanih JQ1.
en-hr
Now, not being a drug company, we could do certain things, we had certain flexibilities, that I respect that a pharmaceutical industry doesn't have.
Non essendo una casa farmaceutica possiamo fare diverse cose, abbiamo una certa flessibilità che l'industria farmaceutica non ha.
en-it
We just started mailing it to our friends.
Chúng tôi bắt đầu gửi nó cho bạn bè chúng tôi.
en-vi
I have a small lab.
我有个小实验室
en-zh-cn
We thought we'd just send it to people and see how the molecule behaves.
Ми думали, що тільки відішлемо молекулу цим людям і побачимо як вона буде поводитись. І ми відіслали її до Оксфорда в Англії,
en-uk
We sent it to Oxford, England, where a group of talented crystallographers provided this picture, which helped us understand exactly how this molecule is so potent for this protein target.
где группа талантливых кристаллографов сделала это изображение, которое помогло нам понять точную причину устойчивости этой молекулы в борьбе с целевым белком. Мы называем это идеальным взаимодополнением посадки и формы,
en-ru
It's what we call a perfect fit of shape complementarity, or hand in glove.
complementaridade de formas, assenta como uma luva. Lembrem-se que este é um cancro muito raro,
en-pt
Now, this is a very rare cancer, this BRD4-addicted cancer.
این سرطان وابسته به BRD4. و درنتیجه ما با نمونه های موادی که توسط آسیب شناسان جوان در بیمارستان زنان بریگام جمع آوری شد کارکردیم.
en-fa
And so we worked with samples of material that were collected by young pathologists at Brigham and Women's Hospital.
koje je skupio mladi patolog u bolnici Brigham Women.
en-hr
And as we treated these cells with this molecule, we observed something really striking.
Και καθώς ακολουθήσαμε αγωγή στα κύτταρα με αυτό το μόριο, παρατηρήσαμε κάτι πραγματικά εντυπωσιακό.
en-el
The cancer cells -- small, round and rapidly dividing, grew these arms and extensions.
Les cellules cancéreuses, petites, rondes et qui se divisent rapidement, ont développé ces bras et ces extensions.
en-fr
They were changing shape.
Те си променяха формата.
en-bg
In effect, the cancer cell was forgetting it was cancer and becoming a normal cell.
Tatsächlich vergaßen sie, dass sie Krebszellen waren und wurden zu normalen Zellen.
en-de
This got us very excited.
Questo ci ha entusiasmati molto.
en-it
The next step would be to put this molecule into mice.
下一步是把这分子注入的老鼠身上
en-zh-cn
The only problem was there's no mouse model of this rare cancer.
ale u dostępnych myszy ten rak nie występuje.
en-pl
And so at the time we were doing this research, I was caring for a 29-year-old firefighter from Connecticut who was very much at the end of life with this incurable cancer.
Și astfel, în timpul în care făceam această cercetare, îngrijeam un pompier de 29 de ani din Connecticut care era foarte aproape de sfârșitul vieții cu acest cancer incurabil.
en-ro
This BRD4-addicted cancer was growing throughout his left lung.
Ten nowotwór powiązany z BRD4 zarastał mu lewe płuco.
en-pl
And he had a chest tube in that was draining little bits of debris.
et il avait un drain thoracique qui évacuait des petits débris. Et à chaque service,
en-fr
And every nursing shift, we would throw this material out.
ما این موادو بیرون میریختیم.
en-fa
And so we approached this patient and asked if he would collaborate with us.
因此我們接觸這位病患 詢問他是否願意與我們合作。
en-zh-tw
Could we take this precious and rare cancerous material from this chest tube and drive it across town and put it into mice and try to do a clinical trial at a stage that with a prototype drug, well, that would be, of course, impossible and, rightly, illegal to do in humans.
und ob wir dieses seltene Tumormaterial aus seinem Brustschlauch entnehmen dürften, um es auf der anderen Seite der Stadt in Mäuse zu implantieren und ein Experiment mit einem neuartigen Medikament zu versuchen. Bei Menschen wäre es unmöglich und natürlich illegal. Er ließ uns gewähren.
en-de
At the Lurie Family Center for Animal Imaging, our colleague, Andrew Kung, grew this cancer successfully in mice without ever touching plastic.
En centro de imagen animal Lurie Family mi colega, Andrew Kung, pudo desarrollar con éxito este cáncer en ratones sin llegar a tocar nunca material de laboratorio.
en-es
And you can see this PET scan of a mouse -- what we call a pet PET.
Ir jūs matote šią pelės PET nuotrauką, kurią mes vadiname "gyvūnėlis PET".
en-lt
The cancer is growing as this red, huge mass in the hind limb of this animal.
El cáncer se extiende como esta enorme masa rojiza en el miembro trasero de ese animal.
en-es