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(Laughter) And so when I make these things, it's really not so much about the object itself, but rather the negative space around the object. | (Gülüşmeler) Ve bu şeyleri yaparken, nesnenın kendisi değil de daha çok nesnenin etrafındaki negatif alanla ilgiliydi. | en-tr |
So what happens when a person puts this thing on? | Peki bir kişi bunu taktığında ne olur? | en-tr |
What kind of an experience do they have? | 그들은 어떤 경험을 하게 될까요? | en-ko |
And how are they transformed by wearing it? | A ako ho nosenie tejto veci zmení? | en-sk |
So many of these devices really kind of focus on the ways in which we relate to ourselves. | Nhiều trong số các thiết bị này thực sự hướng đến những phương thức chúng ta liên hệ với chính mình. | en-vi |
So this particular device is called the Gut Listener. | Вот это устройство называется Кишечный Слухач. | en-ru |
And it is a tool that actually enables one to listen to their own innards. | É uma ferramenta que permite a uma pessoa ouvir as suas próprias entranhas. | en-pt |
(Laughter) And so some of these things are actually more geared toward expression and communication. | （笑） いくつかの器具は意思表現や情報伝達に 大きな重点を置いています | en-ja |
And so the Inflatable Heart is an external organ that can be used by the wearer to express themselves. | Hati Tiup ini organ eksternal yang bisa digunakan untuk berekspresi. | en-id |
So they can actually inflate it and deflate it according to their emotions. | bằng cách thổi phồng lên hoặc làm xẹp xuống tùy theo trạng thái cảm xúc của mình. | en-vi |
So they can express everything from admiration and lust to anxiety and angst. | Man kann also alles ausdrücken, von Bewunderung und Lust zu Beunruhigung und Angst. | en-de |
(Laughter) And some of these are actually meant to mediate experiences. | （笑聲） 有些裝置則是 拿來居中協調的 | en-zh-tw |
So the Discommunicator is a tool for arguments. | Takav je Diskomunikator, uređaj za svađe. | en-hr |
(Laughter) And so actually it allows for an intense emotional exchange, but is serves to absorb the specificity of the words that are delivered. | （笑聲） 你可以很生氣地對著對方大吼大叫 但是這玩意會吸掉 那些很難聽的話 | en-zh-tw |
(Laughter) And in the end, some of these things just act as invitations. | (Ծիծաղ) Վերջ ի վերջո, այս սարքերից ոմանք պարզապես հրավերներ են։ | en-hy |
So the Ear Bender literally puts something out there so someone can grab your ear and say what they have to say. | אז מכופף האוזניים מילולית שם משהו שם כדי שמישהו יוכל לתפוס את אוזניכם ולהגיד מה שיש להם להגיד. | en-he |
So even though I'm really interested in the relationship between people, I also consider the ways in which we relate to the world around us. | 私は対人関係に興味を もっていますが 人々と周辺環境との関わりにも 興味があります | en-ja |
And so when I was first living in New York City a few years back, I was thinking a lot about the familiar architectural forms that surrounded me and how I would like to better relate to them. | 그래서 몇 년 전 제가 처음 뉴욕시로 이사왔을 때, 저는 제 주변에 있는 친숙한 구조물과 어떻게 그것들과 더 잘 어울릴 수 있을까에 대해 많이 생각했었죠 | en-ko |
And I thought, "Well, hey! | Y pensé: "¡listo! | en-es |
Maybe if I want to better relate to walls, maybe I need to be more wall-like myself." | 說不定我是想跟牆壁發展更好的關係 說不定我要更像一面牆。」 | en-zh-tw |
So I made a wearable wall that I could wear as a backpack. | そこで私はリュックのように 背負える壁を作りました | en-ja |
And so I would put it on and sort of physically transform myself so that I could either contribute to or critique the spaces that surrounded me. | Ik deed hem aan en transformeerde mezelf zodat ik zowel iets kon bijdragen aan, of kritiek leveren op de ruimtes die mij omringden. | en-nl |
(Laughter) And so jumping off of that, thinking beyond the built environment into the natural world, I have this ongoing project called Botanicalls -- which actually enables houseplants to tap into human communication protocols. | （笑聲） 現在我們換一種思維 從人造的世界跳到自然的世界 我一直在做一個叫做「植物電話」的實驗─ 這可以讓家裡的植物 跟人類的通訊規則連上線 | en-zh-tw |
So when a plant is thirsty, it can actually make a phone call or post a message to a service like Twitter. | Այսպիսով, երբ բույսը ծարավ է, այն կարող է հեռախոսազանգ կատարել, կամ Twitter-ում գրառում անել։ | en-hy |
And so this really shifts the human/plant dynamic, because a single house plant can actually express its needs to thousands of people at the same time. | Ve insan/ bitki dinamiği değiştirilir, çünkü yalnız bir ev bitkisi aynı anda binlerce insana ihtiyaçlarını ifade edebilir. | en-tr |
And so kind of thinking about scale, my most recent obsession is actually with glaciers -- of course. | และด้วยความคิดเกี่ยวกับขนาดใหญ่แบบนี้ สิ่งที่ฉันกำลังหมกมุ่นในตอนนี้ คือกับธารน้ำแข็ง ---- แน่นอน | en-th |
And so glaciers are these magnificent beings, and there's lots of reasons to be obsessed with them, but what I'm particularly interested in is in human-glacier relations. | Akullnajat jane krijesa mahnitese, dhe ka shume arsye pse mund te jesh i obsesionuar pas tyre, por une vecanerisht jam e interesuar ne marredheniet njeri-akullnaja. | en-sq |
(Laughter) Because there seems to be an issue. | (Nevetés) Elvégre ez fontos témának tűnik. | en-hu |
The glaciers are actually leaving us. | Οι παγετώνες μάς εγκαταλείπουν. | en-el |
They're both shrinking and retreating -- and some of them have disappeared altogether. | Zmenšujú sa a zároveň sa vzďaľujú, pričom niektoré už celkom zmizli. | en-sk |
And so I actually live in Canada now, so I've been visiting one of my local glaciers. | Dakle, zapravo trenutno živim u Kanadi, tako da sam posjetila jednog od mojih lokalnih ledenjaka. | en-hr |
And this one's particularly interesting, because, of all the glaciers in North America, it receives the highest volume of human traffic in a year. | 这真的特别有趣 因为在所以北美洲的冰川中 它是年客流量最高的一座 | en-zh-cn |
They actually have these buses that drive up and over the lateral moraine and drop people off on the surface of the glacier. | بحافلاتهم التي تسير على وفوق الركام الجانبي لإيصال الزائرين إلى سطح النهر المتجمد. | en-ar |
And this has really gotten me thinking about this experience of the initial encounter. | E isto realmente me fez pensar nessa experiência do encontro inicial. | en-pt-br |
When I meet a glacier for the very first time, what do I do? | Kada upoznam glečer po prvi put, šta da radim? | en-sr |
There's no kind of social protocol for this. | Non esiste nessun protocollo particolare. | en-it |
I really just don't even know how to say hello. | Ja zapravo, ne znam ni kako da kažem zdravo. | en-sr |
Do I carve a message in the snow? | האם אני חוצבת הודעה בשלג? | en-he |
Or perhaps I can assemble one out of dot and dash ice cubes -- ice cube Morse code. | หรือบางทีฉันอาจรวบรวม ก้อนน้ำแข็ง ทำเป็นจุดกับเป็นขีด แบบทำรหัสมอร์สจากน้ำแข็ง | en-th |
Or perhaps I need to make myself a speaking tool, like an icy megaphone that I can use to amplify my voice when I direct it at the ice. | Oder vielleicht muss ich mir ein Sprechwerkzeug basteln, wie ein Eis-Megafon, das meine Stimme verstärkt wenn ich es auf das Eis richte. | en-de |
But really the most satisfying experience I've had is the act of listening, which is what we need in any good relationship. | 但我曾有过最得意的经验其实是 关于聆听的 任何好的关系都需要我们有聆听的技巧 | en-zh-cn |
And I was really struck by how much it affected me. | Wpłynęło to na mnie w zaskakujący sposób. | en-pl |
This very basic shift in my physical orientation helped me shift my perspective in relation to the glacier. | Ez a rendkívül egyszerű megváltoztatása a fizikai elhelyezkedésemnek segített új nézőpontot találni a gleccserekhez fűződő kapcsolatom tekintetében. | en-hu |
And so since we use devices to figure out how to relate to the world these days, I actually made a device called the Glacier Embracing Suit. | Và bởi vì chúng ta dùng các thiết bị để tìm cách kết nối với thế giới ngày nay, tôi đã thật sự tạo ra một thiết bị gọi là "Trang phục ôm băng" | en-vi |
(Laughter) And so this is constructed out of a heat reflected material that serves to mediate the difference in temperature between the human body and the glacial ice. | (smiech) Takže ten je vyrobený z materiálu odrážajúceho teplo, ktorý slúži na sprostredkovanie rozdielu v teplote medzi ľudským telom a ľadovcom. | en-sk |
And once again, it's this invitation that asks people to lay down on the glacier and give it a hug. | 그리고 다시 한 번, 이것은 사람들에게 빙하에 엎드려서 포옹 한 번 해달라고 요청하는 초대장이에요 | en-ko |
So, yea, this is actually just the beginning. | Pero esto, en realidad, es sólo el comienzo. | en-es |
These are initial musings for this project. | Són idees inicials per aquest projecte. | en-ca |
And just as with the wall, how I wanted to be more wall-like, with this project, I'd actually like to take more a of glacial pace. | E come per il muro, con il mio voler essere più 'muro', con questo progetto vorrei davvero fare più parte del ghiacciaio. | en-it |
And so my intent is to actually just take the next 10 years and go on a series of collaborative projects where I work with people from different disciplines -- artists, technologists, scientists -- to kind of work on this project of how we can improve human-glacier relations. | ดังนั้นความตั้งใจของฉัน คือในอีก 10 ปีข้างหน้า จะมีโปรเจ็คความร่วมมือต่างๆ ในครั้งต่อๆ ไป ที่ซึ่งฉันทำงานกับคนจากหลากหลายสาขา ศิลปิน ผู้เชี่ยวชาญทางเทคโนโลยี นักวิทยาศาสตร์ มาทำงานร่วมกัน เพื่อหาว่าเราจะพัฒนาความสัมพันธ์ธารน้ำแข็งกับคนได้อย่างไร | en-th |
So beyond that, in closing, I'd just like to say that we're in this era of communications and device proliferation, and it's really tremendous and exciting and sexy, but I think what's really important is thinking about how we can simultaneously maintain a sense of wonder and a sense of criticality about the tools that we use and the ways in which we relate to the world. | وأبعد من ذلك، ففي الختام، أود أن أشير إلى أننا في هذا العصر الذي يشهد طفرة في الإتصالات وإنتشار أجهزته، وهذا بالطبع غاية في الإثارة والرواعة، مع إعتقادي بأنه من الضرورة بمكان التفاكر حول كيفية للمحافظة على حس الإثارة والعنصر النقدي في آن واحد حول الأدوات التي نستخدمها والطرق التي نتعامل بها مع العالم. | en-ar |
Ladies and gentlemen, I present to you the human genome. | Doamnelor şi domnilor, Vă prezint genomul uman! | en-ro |
(Applause) Chromosome one -- top left, bottom right -- are the sex chromosomes. | (Applåder) Kromosom 1, längst upp till vänster. Längst ner till höger hittar ni könskromosomerna. | en-sv |
Women have two copies of that big X chromosome; men have the X and, of course, that small copy of the Y. | ถ้าเป็นผู้หญิงก็จะมีโครโมโซม X ตัวใหญ่นี้อยู่ 2 ตัว ผู้ชายก็จะมีโครโมโซม X และแน่นอนก็จะมีเจ้าโครโมโซม Y ตัวเล็กๆ นี่อีกหนึ่ง | en-th |
Sorry boys, but it's just a tiny little thing that makes you different. | 男性の皆さん 残念ですがY染色体は こんなに小さいんです | en-ja |
So if you zoom in on this genome, then what you see, of course, is this double-helix structure -- the code of life spelled out with these four biochemical letters, or we call them bases: A, C, G and T. | Om man zoomar in på det här genomet så kommer man se den här strukturen, den dubbla helixen – livets kod skrivet med dessa fyra biokemiska bokstäver, som vi kallar baspar, eller hur? A, C, G och T. | en-sv |
How many are there in the human genome? Three billion. | כמה כאלה יש בגנום האנושי? 3 מיליארד. | en-he |
Is that a big number? | Është ky një numër i madh? | en-sq |
Well, everybody can throw around big numbers. | Pa, svatko se može razbacivati velikim brojevima. | en-hr |
But in fact, if I were to place one base on each pixel of this 1280x800-resolution screen, we would need 3,000 screens to take a look at the genome. | Ama şunu ifade etmeliyim ki eğer bu 1280X800 çözünürlüğündeki ekranın herbir pikseline bir baz yerleştirecek olsaydım, insan genomunun tamamını görebilmek için 3000 adet ekrana ihtiyacımız olurdu. | en-tr |
So it's really quite big. | Vì thế con số đó thật sự là lớn. | en-vi |
And perhaps because of its size, a group of people -- all, by the way, with Y chromosomes -- decided they would want to sequence it. | 也许因为这个规模的缘故 一群人－都是带Y染色体的 他们决定进行测序 | en-zh-cn |
(Laughter) And so 15 years, actually, and about four billion dollars later, the genome was sequenced and published. | （笑） 15年と40億ドルのお金をかけて ゲノムの配列が解析・公表されました | en-ja |
In 2003, the final version was published, and they keep working on it. | 2003-ban közölték a végleges változatot, és folyamatosan dolgoznak rajta. | en-hu |
That was all done on a machine like this. | 這一切都是在這樣的一台儀器上完成的。 每排序一個基對花費一美元左右 | en-zh-tw |
It costs about a dollar for each base -- a very slow way of doing it. | une méthode vraiment très lente. | en-fr |
Well, folks, I'm here to tell you that the world has completely changed, and none of you know about it. | Eh bien, les gars, je suis ici pour vous dire que le monde a complètement changé et que personne ici n'est au courant. | en-fr |
So now what we do is take a genome, we make maybe 50 copies of it, we cut all those copies up into little 50-base reads, and then we sequence them, massively parallel. | Отже, тепер ми робимо так - ми беремо геном, ми робимо десь 50 його копій, ріжемо ці копії на шматочки в 50 основ, і секвенуємо їх усі паралельно. | en-uk |
Then we bring that into software and reassemble it, and tell you what the story is. | Depois, trazemos isso para o software, juntamos tudo de novo e contamos-vos qual é a história. | en-pt |
So to give you a picture of what this looks like, the Human Genome Project: 3 gigabases, right? | פרוייקט הגנום האנושי: 3 ג'יגה-בסיסים. על מכשיר כזה: | en-he |
One run on one of these modern machines: 200 gigabases in a week. | udělá 200 gigabází za týden. | en-cs |
And that 200 is going to change to 600 this summer, and there's no sign of this pace slowing. | Och de 200 kommer till sommaren vara 600 och det finns inget som tyder på att takten minskar. | en-sv |
The price of a base, to sequence a base, has fallen 100 million times. | Takže, cena báze, sekvenováni na jednu bázi, klesla stomilionkrát. | en-cs |
That's the equivalent of you filling up your car with gas in 1998, waiting until 2011, and now you can drive to Jupiter and back twice. | Αυτό είναι αντίστοιχο με το να γεμίζατε το αυτοκίνητό σας με βενζίνη το 1998, να περιμένατε μέχρι το 2011, και τώρα μπορείτε να οδηγήσετε έως τον Δία και πίσω δύο φορές. | en-el |
(Laughter) World population, PC placements, the archive of all of medical literature, Moore's law, the old way of sequencing, and here's all the new stuff. | (웃음) 세계 인구, 컴퓨터 보급대수, 모든 의료 문헌기록, 무어 법칙, 옛날 분석방법, 그리고 새로운 분석법들입니다. 여러분 여기 로그 스케일이 보이시죠. | en-ko |
Guys, this is a long scale; you don't typically see lines that go up like that. | de obicei, nu vedeţi linii care urcă astfel. | en-ro |
So the worldwide capacity to sequence human genomes is something like 50,000 to 100,000 human genomes this year. | La capacidad mundial para secuenciar genomas humanos está entre 50.000 y 10.000 este año. | en-es |
We know this based on the machines that are being placed. | และเรารู้สิ่งนี้ได้จากเครื่องมือที่กำลังจะถูกติดตั้ง | en-th |
This is expected to double, triple or maybe quadruple year over year for the foreseeable future. | Yakın gelecekte bu rakamın ikiye, üçe, hatta dörde katlanması beklenmektedir. | en-tr |
In fact, there's one lab in particular that represents 20 percent of all that capacity: It's called the Beijing Genomics Institute. | 实际上，有一个实验室 具备所有测序能力中的百分之二十 就是华大基因 | en-zh-cn |
The Chinese are absolutely winning this race to the new Moon, by the way. | 중국은 정말로 새로운 달로 가는 경쟁에서 완전히 앞서나가고 있습니다. | en-ko |
What does this mean for medicine? | 對於醫學這意味著甚麼呢？ | en-zh-tw |
So a woman, age 37, presents with stage 2 estrogen receptor-positive breast cancer. | Sievietei ir 37 gadi. Viņai ir estrogēnu receptoru pozitīvs krūts vēzis 2. stadijā. | en-lv |
She is treated with surgery, chemotherapy and radiation. | 수술, 화학치료, 방사선 치료를 받고 | en-ko |
She goes home. | ذهبت إلى بيتها. | en-ar |
Two years later, she comes back with stage 3C ovarian cancer, unfortunately; treated again with surgery and chemotherapy. | Dois anos depois, volta com cancro do ovário, grau III. Infelizmente, é tratada novamente com cirurgia e quimioterapia. | en-pt |
She comes back three years later at age 42 with more ovarian cancer, more chemotherapy. | Három év múlva visszajön 42 évesen újra petefészekrákkal és újra kemoterápiát kap. | en-hu |
Six months later, she comes back with acute myeloid leukemia. | 6 เดือนต่อมา เธอก็กลับมาด้วยโรคมะเร็งเม็ดเลือดขาวเฉียบพลันชนิดไมอีลอยด์ | en-th |
She goes into respiratory failure and dies eight days later. | Παθαίνει αναπνευστική ανεπάρκεια και πεθαίνει οκτώ ημέρες αργότερα. | en-el |
So first: the way in which this woman was treated, in as little as 10 years, will look like bloodletting. | Öncelikle şunu söyleyeyim, bu kadına uygulanan tedavi 10 yıl kadar bir zaman sonra, kan alma işleminden farklı olmayacak. | en-tr |
And it's because of people like my colleague, Rick Wilson, at the Genome Institute at Washington University, who decided to take a look at this woman postmortem. | 그건 워싱턴 대학교의 게놈 연구소에 있는 제 동료인 릭 윌슨과 같은 사람들이 사후에 이 여성에 대해 연구를 하기 결정했기 때문입니다. 그는 서열 분석을 했슨데, 건강한 피부 세포와 | en-ko |
And he took skin cells, healthy skin and cancerous bone marrow, and sequenced the whole genomes of both of them in a couple of weeks, no big deal. | и костен мозък заразен с рак, и секвенирал и двете проби, за няколко седмици -- нищо работа. | en-bg |
Then he compared those two genomes in software, and what he found, among other things, was a deletion -- a 2,000-base deletion across three billion bases in a particular gene called TP53. | Então ele comparou esses 2 genomas no software, e o que encontrou, entre outras coisas, foi a deleção, uma deleção de 2.000 bases através de 3 bilhões de bases de um gene em particular chamado TP53. Se você tiver essa mutação prejudicial neste gene, | en-pt-br |
If you have this deleterious mutation in this gene, you're 90 percent likely to get cancer in your life. | thì 90% bạn có nguy cơ bị ung thư trong cuộc đời. | en-vi |
So unfortunately, this doesn't help this woman, but it does have severe -- profound, if you will -- implications to her family. | Perciò, in questo caso, sfortunatamente, ciò non aiuta la donna, ma ha gravi, profonde se vogliamo, implicazioni per la sua famiglia. | en-it |
I mean, if they have the same mutation, and they get this genetic test and they understand it, then they can get regular screens and can catch cancer early, and potentially live a significantly longer life. | 만일 그 가족들이 똑같은 돌연변이가 있다면, 유전자 테스트를 통해서 그걸 알게 될거고, 정기적인 검사를 통해서 암을 빨리 발견해 내겠죠 그리고 아마도 훨씬 더 오래 살 수 있을 것입니다. | en-ko |
Let me introduce you to the Beery twins, diagnosed with cerebral palsy at the age of two. | Laissez-moi vous présenter les jumeaux Beery, dont la paralysie cérébrale a été diagnostiquée quand ils avaient 2 ans. | en-fr |
Their mom is a very brave woman who didn't believe it; the symptoms weren't matching up. | Su mamá es una mujer muy valiente que no creía que los síntomas estaban coincidiendo, y que gracias a un esfuerzo heroico y a muchas horas de búsqueda en Internet, | en-es |
And through some heroic efforts and a lot of Internet searching, she was able to convince the medical community that, in fact, they had something else. | הצליחה לשכנע את הקהילה המדעית שלמעשה יש להם משהו אחר. מה שהיה להם זו דיסטוניה המגיבה לדופמין DRD. | en-he |
And so they were given L-Dopa, and their symptoms did improve, but they weren't totally asymptomatic. | A tak keď dostali L-DOPA ich symptómy sa zlepšili, ale neboli úplne bez príznakov. | en-sk |
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