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A meta-analysis reported that vitamin D supplementation significantly reduced the risk of type 2 diabetes for non-obese people with prediabetes. Another meta-analysis reported that vitamin D supplementation significantly improved glycemic control [homeostatic model assessment-insulin resistance (HOMA-IR)], hemoglobin A...
1
Applied and Interdisciplinary Chemistry
GLD-2 primarily stabilizes mRNAs that are translationally repressed as well as it strongly promotes bulk polyadenylation. Surprisingly, those functions seem to have little impact on dynamizing efficient target mRNA translation, as it is an efficient Poly(A) Polymerase which helps developing polyadenylation activity. Th...
1
Applied and Interdisciplinary Chemistry
Two of the drugs three components were originally developed at the Public Health Agency of Canadas National Microbiology Laboratory (NML), and a third at the U.S. Army Medical Research Institute of Infectious Diseases; the cocktail was optimized by Gary Kobinger, then branch chief of the NML, and is undergoing further ...
1
Applied and Interdisciplinary Chemistry
Some are generated from the reaction of low-valence metal complexes with azides: :LM + NR → LMNR + N A few imido complexes have been generated by the alkylation of metal nitride complexes: :LMN + RX → LMNR + X
0
Theoretical and Fundamental Chemistry
Batch reactors are reactors in which the reactants are put in the reactor at time 0 and react until the reaction is stopped. Consequently, the space time is the same as the average residence time in a batch reactor.
0
Theoretical and Fundamental Chemistry
In molecular biology, a scissile bond is a covalent chemical bond that can be broken by an enzyme. Examples would be the cleaved bond in the self-cleaving hammerhead ribozyme or the peptide bond of a substrate cleaved by a peptidase.
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Applied and Interdisciplinary Chemistry
Prolonged exposure to pyridine may result in liver, heart and kidney damage. Evaluations as a possible carcinogenic agent showed that there is inadequate evidence in humans for the carcinogenicity of pyridine, although there is sufficient evidence in experimental animals. Therefore, IARC considers pyridine as possibly ...
0
Theoretical and Fundamental Chemistry
As with synthetic kinetic resolution procedures, enzymatic acylation kinetic resolutions have seen the broadest application in a synthetic context. Especially important has been the use of enzymatic kinetic resolution to efficiently and cheaply prepare amino acids. On a commercial scale, Degussa's methodology employing...
0
Theoretical and Fundamental Chemistry
The volume of distribution of levetiracetam is similar to total body water. Levetiracetam modestly binds to plasma proteins (less than 10%).
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Theoretical and Fundamental Chemistry
Ct analysis, a technique based on the principles of DNA reassociation kinetics, is a biochemical technique that measures how much repetitive DNA is in a DNA sample such as a genome. It is used to study genome structure and organization and has also been used to simplify the sequencing of genomes that contain large amo...
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Applied and Interdisciplinary Chemistry
Evolution of proteins is slower than DNA since only nonsynonymous mutations in DNA can result in amino acid replacements. Most mutations are neutral to maintain protein function and structure. Therefore, the more similar amino acids are, the more probable that they will be replaced. Conservative replacements are more c...
1
Applied and Interdisciplinary Chemistry
After Masri came back from Washington DC to Palestine in Mid-1990s to establish himself in his home country, he started by founding Palestinians daily newspaper "Al-Ayyam Newspaper (/Arabic: جريدة الأيام/)" and was its publisher. Al Ayyam is today the second largest newspaper in Palestine.
1
Applied and Interdisciplinary Chemistry
During the formation of neutron stars, or in radioactive isotopes capable of electron capture, neutrons are created by electron capture: This is similar to the inverse beta reaction in that a proton is changed to a neutron, but is induced by the capture of an electron instead of an antineutrino.
0
Theoretical and Fundamental Chemistry
Operando UV-vis spectroscopy is particularly useful for many homogeneous catalytic reactions because organometallic species are often colored. Fiber-optical sensors allow monitoring of the consumption of reactants and production of product within the solution through absorption spectra. Gas consumption as well as pH an...
0
Theoretical and Fundamental Chemistry
Apart from uses in coatings and adhesives they are also used to enhance the performance of polyester tire cord. Other uses include Powder coatings, Coil Coatings, Cationic Electrocoating and primers. Blocked isocyanates have also been used in tertiary oilfield recovery techniques. A blocked isocyanate is pumped into th...
0
Theoretical and Fundamental Chemistry
Bulky ligands are used to control the steric properties of a metal center. They are used for many reasons, both practical and academic. On the practical side, they influence the selectivity of metal catalysts, e.g., in hydroformylation. Of academic interest, bulky ligands stabilize unusual coordination sites, e.g., rea...
0
Theoretical and Fundamental Chemistry
The name is derived from the word kermes as denoting the compound’s red color. The origins of the term is from the French kermès, which is short for alkermès, from the Arabic al-qirmiz a reference to crimson dye made from the bodies of insects (see Kermes (dye)). It was also known as poudre des Chartreux from a stor...
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Applied and Interdisciplinary Chemistry
Typical coatings that can be evaluated with this method are: *Phosphated (pre-treated) surfaces (with subsequent paint/primer/lacquer/rust preventive) *Zinc and zinc-alloy plating (see also electroplating). See ISO 4042 for guidance *Electroplated chromium, nickel, copper, tin *Coatings not applied electrolytically, su...
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Applied and Interdisciplinary Chemistry
In early 2004, Novartis Pharmaceuticals have disclosed the detail of a 60g-scale synthesis of (+)-discodermolide. This synthesis utilized the Smith gram-scale approach and the Paterson first-generation endgame. This synthesis allows (+)-discodermolide to be evaluated as an in vivo chemotherapeutic agent for adult pati...
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Theoretical and Fundamental Chemistry
As noted, these number about 251. For a list, see the article list of elements by stability of isotopes. For a complete list noting which of the "stable" 251 nuclides may be in some respect unstable, see list of nuclides and stable nuclide. These questions do not impact the question of whether a nuclide is primordial, ...
0
Theoretical and Fundamental Chemistry
The ocean's alkalinity varies over time, most significantly over geologic timescales (millennia). Changes in the balance between terrestrial weathering and sedimentation of carbonate minerals (for example, as a function of ocean acidification) are the primary long-term drivers of alkalinity in the ocean. Over human tim...
0
Theoretical and Fundamental Chemistry
Maxwells model was not the first plaster model of a thermodynamic surface: in 1871, even before Gibbs papers, James Thomson had constructed a plaster pressure-volume-temperature plot, based on data for carbon dioxide collected by Thomas Andrews. Around 1900, the Dutch scientist Heike Kamerlingh Onnes, together with his...
0
Theoretical and Fundamental Chemistry
* German Chemical Society (GDCh), since 1995 * American Chemical Society (ACS), since 1997 * Royal Society of Chemistry (RSC), since 2011
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Theoretical and Fundamental Chemistry
The volume concentration (not to be confused with volume fraction) is defined as the volume of a constituent divided by the volume of the mixture : Being dimensionless, it is expressed as a number, e.g., 0.18 or 18%; its unit is 1. There seems to be no standard notation in the English literature. The letter used her...
0
Theoretical and Fundamental Chemistry
Some crops are grown under the protective shelter of different kinds of plant, whether as wind breaks or for shade. For example, shade-grown coffee, especially Coffea arabica, has traditionally been grown in light shade created by scattered trees with a thin canopy, allowing light through to the coffee bushes but prote...
1
Applied and Interdisciplinary Chemistry
In 1919, he was elected a Fellow of the Royal Society of Edinburgh. His proposers were Alexander Gray, George Alexander Gibson, John Glaister, Diarmid Noel Paton, Ralph Stockman, Thomas Hastie Bryce, Robert Muir, Frederick Orpen Bower and Robert Alexander Houston. He resigned from the Society in 1931. He retired in 194...
0
Theoretical and Fundamental Chemistry
A kaliapparat is a laboratory device invented in 1831 by Justus von Liebig (1803–1873) for the analysis of carbon in organic compounds. The device, made of glass, consists of a series of five bulbs connected and arranged in a triangular shape. To determine the carbon in an organic compound with a kaliapparat, the subst...
0
Theoretical and Fundamental Chemistry
Bahadurs publications were ambivalently received, and the overall attention of the scientific community seemed limited since Krishna Bahadur and his co-workers reported that the Jeewanus are alive (a striking statement), the team changed the protocols frequently and documented them somewhat idiosyncratically. Bahadur d...
0
Theoretical and Fundamental Chemistry
An important concept in thermodynamics is the thermodynamic system, which is a precisely defined region of the universe under study. Everything in the universe except the system is called the surroundings. A system is separated from the remainder of the universe by a boundary which may be a physical or notional, but se...
0
Theoretical and Fundamental Chemistry
The Johnson–Claisen rearrangement is the reaction of an allylic alcohol with an ortho ester containing a deprotonatable alpha carbon (e.g. triethyl orthoacetate) to give a ester.
0
Theoretical and Fundamental Chemistry
UTP also has the role of a source of energy or an activator of substrates in metabolic reactions, like that of ATP, but more specific. When UTP activates a substrate (like Glucose-1-phosphate), UDP-glucose is formed and inorganic phosphate is released. UDP-glucose enters the synthesis of glycogen. UTP is used in the ...
1
Applied and Interdisciplinary Chemistry
This section is not concerned with sculpture in bronze, but rather with the many artistic applications of the metal in connection with architecture, or with objects for ecclesiastical and domestic use. Why bronze was preferred in Italy, iron in Spain and Germany and brass in the Low Countries cannot be satisfactorily d...
1
Applied and Interdisciplinary Chemistry
Fluoride () is an inorganic, monatomic anion of fluorine, with the chemical formula (also written ), whose salts are typically white or colorless. Fluoride salts typically have distinctive bitter tastes, and are odorless. Its salts and minerals are important chemical reagents and industrial chemicals, mainly used in t...
1
Applied and Interdisciplinary Chemistry
ADVB-PA Award – Association of Sales and Marketing Managers from Brazil: Top Environmental Company Award, 2012.
1
Applied and Interdisciplinary Chemistry
Flat roofs – 1% to 2% slope Low slope-3:12 to 5:12 Medium Slope-6:12 to 9:12 High Slope-10:12 to 12:12 ;Subtropical regions in the US where SCV roofs could apply Here are some of the states where humid subtropical climates can be found: * Eastern half of Texas * Louisiana * Arkansas * Alabama * Mississippi * North Caro...
1
Applied and Interdisciplinary Chemistry
With deep WGS data of cfDNA from a carcinoma of unknown primary patient with very low ctDNA concentration quantified, they trained a machine learning model using bootstrapping. The results of RNA-sequencing on PBMC runs for the 5 different patients are recorded and the average of 3 of these individuals expression level...
1
Applied and Interdisciplinary Chemistry
The compound crystallizes in a tetragonal body-centered unit cell of space group symmetry I4md. In the solid-state diethylzinc shows nearly linear Zn centres. The Zn-C bonds measure 194.8(5) pm, while the C-Zn-C angle is slightly bent with 176.2(4)°. The structure of the gas-phase shows a very similar Zn-C distance (19...
0
Theoretical and Fundamental Chemistry
When symptoms of the essential tremors are considerably high, non-selective β-blockers are an important treatment option and usually the first choice. Studies have shown that propranolol did reduce symptoms the most in that category. The β-blockers can be used alone or in a combination.
1
Applied and Interdisciplinary Chemistry
Cavendish died at Clapham on 24 February 1810 (as one of the wealthiest men in Britain) and was buried, along with many of his ancestors, in the church that is now Derby Cathedral. The road he used to live on in Derby has been named after him, as has a road near his house in Clapham, of which the north part is part of ...
1
Applied and Interdisciplinary Chemistry
Metal sulfides (e.g., pyrite FeS, arsenopyrite FeAsS, chalcopyrite CuFeS) are normally processed by chemical oxidation either in aqueous media or at high temperatures. In fact, most base metals, e.g., aluminium, chromium, must be (electro)chemically reduced at high temperatures by which the process entails a high energ...
1
Applied and Interdisciplinary Chemistry
To explain the wide range of isotopic compositions observed among the amino acids, it is necessary to consider how isotopes are sorted between starting materials, intermediates, and products in reaction networks. Amino acid biosynthesis pathways contain both reversible and irreversible reactions, as well as branch poin...
0
Theoretical and Fundamental Chemistry
The use of peptides as drugs has some disadvantages because of their bioavailability and biostability. Rapid degradation, poor oral availability, difficult transportation through cell membranes, nonselective receptor binding, and challenging multistep preparation are the major limitations of peptides as active pharmace...
0
Theoretical and Fundamental Chemistry
The mass of the atoms forming a chemical bond affects the bond’s strength. When two different isotopes of the same element exist, the heavier ones form stronger bonds. Stronger bonds make bond cleavage reactions run more slowly, leading to the kinetic isotope effect, a well-studied concept in physical chemistry. To ill...
0
Theoretical and Fundamental Chemistry
Neptunes moon Triton is observed to have the reddish color characteristic of tholins. Tritons atmosphere is mostly nitrogen, with trace amounts of methane and carbon monoxide.
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Theoretical and Fundamental Chemistry
McDermott obtained her Bachelor of Science in Chemistry from Harvey Mudd College in Claremont, CA in 1981. In 1988, she obtained her doctoral degree at U.C. Berkeley in the Department of Chemistry with Kenneth Sauer and Melvin Klein.
0
Theoretical and Fundamental Chemistry
In internal combustion engines, exhaust gas recirculation (EGR) is a nitrogen oxide () emissions reduction technique used in petrol/gasoline, diesel engines and some hydrogen engines. EGR works by recirculating a portion of an engine's exhaust gas back to the engine cylinders. The exhaust gas displaces atmospheric air...
1
Applied and Interdisciplinary Chemistry
In 2007 the New Zealand Society of Plant Biologists renamed their annual award after Slack. The award is made to society members to recognise an outstanding contribution to the study of plant biology. It was renamed in recognition of his outstanding contribution as a plant biologist and biochemist in New Zealand, his r...
1
Applied and Interdisciplinary Chemistry
The Ray–Dutt twist is a mechanism proposed for the racemization of octahedral complexes containing three bidentate chelate rings. Such complexes typically adopt an octahedral molecular geometry in their ground states, in which case they possess helical chirality. The pathway entails formation of an intermediate of C ...
0
Theoretical and Fundamental Chemistry
Plants express the mechanistic target of rapamycin (mTOR) and have a TOR kinase complex. In plants, only the TORC1 complex is present unlike that of mammalian target of rapamycin which also contains the TORC2 complex. Plant species have TOR proteins in the protein kinase and FKBP-rapamycin binding (FRB) domains that sh...
1
Applied and Interdisciplinary Chemistry
Fluorescent X-rays are scattered by atoms in a sample and provide the object wave, which is referenced to non-scattered X-rays. A holographic pattern is recorded by scanning a detector around the sample, which allows researchers to investigate the local 3D structure around a specific element in a sample.
0
Theoretical and Fundamental Chemistry
Soon after the first demonstration of hyper Rayleigh scattering optical activity in metal nanoparticles, the effect was replicated in organic molecules, specifically aromatic oligoamide foldamers.
0
Theoretical and Fundamental Chemistry
Eoxin A4, also known as 14,15-leukotriene A4, is an eoxin. Cells make eoxins by metabolizing arachidonic acid with a 15-lipoxygenase enzyme to form 15(S)-hydroperoxyeicosapentaenoic acid (i.e. 15(S)-HpETE). This product is then converted serially to eoxin A4 (i.e. EXA4), EXC4, EXD4, and EXE4 by LTC4 synthase, an uniden...
1
Applied and Interdisciplinary Chemistry
Some naturally occurring isotopes are entirely radiogenic, but all those are radioactive isotopes, with half-lives too short to have occurred primordially and still exist today. Thus, they are only present as radiogenic daughters of either ongoing decay processes, or else cosmogenic (cosmic ray induced) processes that ...
0
Theoretical and Fundamental Chemistry
Accurate determination of core temperature often requires a special low temperature thermometer, as most clinical thermometers do not measure accurately below . A low temperature thermometer can be placed in the rectum, esophagus or bladder. Esophageal measurements are the most accurate and are recommended once a perso...
1
Applied and Interdisciplinary Chemistry
In 2015 the use of highly porous, catalyst-decorated COFs for converting carbon dioxide into carbon monoxide was reported. MOF under solvent-free conditions can also be used for catalytic activity in the cycloaddition of CO and epoxides into cyclic organic carbonates with enhanced catalyst recyclability.
0
Theoretical and Fundamental Chemistry
The Austrian pharmaceutical company, Biochemie, was founded in Kundl in July 1946 at the site of a derelict brewery, at the suggestion of a French officer, Michel Rambaud (a chemist), who was able to obtain a small amount of Penicillium start culture from France. Contamination of the fermentation tanks was a persistent...
0
Theoretical and Fundamental Chemistry
Metal foams are popular support for electrocatalysts due to the high surface area and stable structure. The interconnected pores also benefit the mass transport of reactants and products. However, the benchmark of electrocatalysts can be difficult due to the undetermined surface area, different foam properties, and cap...
0
Theoretical and Fundamental Chemistry
Early diffusion models postulated that atomic motion in substitutional alloys occurs via a direct exchange mechanism, in which atoms migrate by switching positions with atoms on adjacent lattice sites. Such a mechanism implies that the atomic fluxes of two different materials across an interface must be equal, as each...
1
Applied and Interdisciplinary Chemistry
The output of SAGE is a list of short sequence tags and the number of times it is observed. Using sequence databases a researcher can usually determine, with some confidence, from which original mRNA (and therefore which gene) the tag was extracted. Statistical methods can be applied to tag and count lists from differ...
1
Applied and Interdisciplinary Chemistry
The sample should be vacuum stable. It is typically mounted using a conductive compound (e.g. an epoxy thermoset filled with Cu), which minimises image drift and sample charging under electron beam irradiation. EBSP quality is sensitive to surface preparation. Typically the sample is ground using SiC papers from 240 do...
0
Theoretical and Fundamental Chemistry
Dr Mukherjee was able to foresee how basic soil colloid studies could be of help in understanding many of the soil properties and problems. He brought to use in the study of the soil all the tools and techniques he had been developing and improving through years of patient research. In 1942, with N.C. Sen Gupta, he de...
0
Theoretical and Fundamental Chemistry
The 19th century (1800s) birthed "pharmacy as we know it." And again, pharmacy's development in mainland Europe continued to fuel its growth in the young American republic.
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Applied and Interdisciplinary Chemistry
Water-based defoamers are different types of oils and waxes dispersed in a water base. The oils are often mineral oil or vegetable oils and the waxes are long chain fatty alcohol, fatty acid soaps or esters. These are normally best as deaerators, which means they are best at releasing entrained air.
0
Theoretical and Fundamental Chemistry
In 2006, Pilot Pens Inc. developed a pen with erasable ink that utilized thermochromic ink. It was composed of a solvent, a colorant, and a resin film-forming agent. At temperatures below 65 °C, the ink stayed in a colored state. Once temperatures went above 65 °C, the ink began to melt and became colorless, creating t...
0
Theoretical and Fundamental Chemistry
The earliest example of a [4+4] photocycloaddition was the photodimerization of anthracene, discovered in 1936. This reaction has remained one of the most reliable photocycloadditions and is the basis of continuing investigation. Other polycyclic aromatics undergo anthracene-like photocycloaddition, such as acridiziniu...
0
Theoretical and Fundamental Chemistry
Charles Wood (1702 – October 1774) was an English ironmaster and one of the inventors of the potting and stamping method of making wrought iron from pig iron.
1
Applied and Interdisciplinary Chemistry
In the field of cellular biology, single-cell analysis and subcellular analysis is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level. The concept of single-cell analysis originated in the 1970s. Before the discovery of heterogeneity, single-cell analys...
1
Applied and Interdisciplinary Chemistry
*[http://www.arabianbusiness.com/mohammad-baloola-interview-beating-bulge-446743.html Mohammad Baloola interview: Beating the bulge – Arabian Business Magazine] *[http://gulfnews.com/news/gulf/uae/education/diabetes-invention-inches-closer-to-development-1.942614 Diabetes invention inches closer to development – Gulf N...
0
Theoretical and Fundamental Chemistry
With fewer ions, the electric field increases, resulting in electrons with energy of about 2 eV, which is enough to excite atoms and produce light. With longer glow discharge tubes, the longer space is occupied by a longer positive column, while the cathode layer remains the same. For example, with a neon sign, the p...
0
Theoretical and Fundamental Chemistry
External fans are provided to give sufficient air for combustion. The Primary air fan takes air from the atmosphere and, first warms the air in the air preheater for better economy. Primary air then passes through the coal pulverizers, and carries the coal dust to the burners for injection into the furnace. The Seconda...
1
Applied and Interdisciplinary Chemistry
Sintering and hot isostatic pressing are processing techniques used to densify materials from a loosely packed "green body" into a solid object with physically merged grains. Sintering occurs below the melting point, and causes adjacent particles to merge at their boundaries, creating a strong bond between them. In hot...
1
Applied and Interdisciplinary Chemistry
Lovastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. Mevalonate is a required building block for cholesterol biosynthesis and lovastatin interferes with its production by acting as a reversible competitive in...
0
Theoretical and Fundamental Chemistry
Fluorescence spectroscopy is a technique that is used to assay a sample using a fluorescent probe. DNA nucleotides themselves are not good candidates for this technique because they do not readily re-emit light upon light excitation. A fluorescent marker is needed to detect base flipping. 2-Aminopurine is a base tha...
1
Applied and Interdisciplinary Chemistry
Porphyrins have been investigated as possible anti-inflammatory agents and evaluated on their anti-cancer and anti-oxidant activity. Several porphyrin-peptide conjugates were found to have antiviral activity against HIV in vitro.
1
Applied and Interdisciplinary Chemistry
Waxes prepared with BTA are available commercially, the idea being that the BTA will prevent any reaction by chelating the surface copper and the wax acting as a physical barrier reducing exposure to water, oxygen, and chlorides; but coating an infected object with wax will not stop the problem. Storing the object in a...
1
Applied and Interdisciplinary Chemistry
Benzene is an excellent ligand in the organometallic chemistry of low-valent metals. Important examples include the sandwich and half-sandwich complexes, respectively, Cr(CH) and [[(Benzene)ruthenium dichloride dimer|[RuCl(CH)]]].
1
Applied and Interdisciplinary Chemistry
The enzymatic mechanism of influenza virus sialidase has been studied by Taylor et al., shown in Figure 1. The enzyme catalysis process has four steps. The first step involves the distortion of the α-sialoside from a C chair conformation (the lowest-energy form in solution) to a pseudoboat conformation when the sialosi...
0
Theoretical and Fundamental Chemistry
Copper chromite is an inorganic compound with the formula CuCrO. It is a black solid that is used to catalyze reactions in organic synthesis.
0
Theoretical and Fundamental Chemistry
Lanthanides can be used because their small size (ionic radius) gives them the ability to replace metal ions inside protein complex such as calcium or nickel. The optical properties of lanthanide ions such as Ln(III) originate in the special features of their electronic [Xe]4f configurations. These configurations gener...
1
Applied and Interdisciplinary Chemistry
Most pristine rivers will have a 5-day carbonaceous BOD below 1 mg/L. Moderately polluted rivers may have a BOD value in the range of 2 to 8 mg/L. Rivers may be considered severely polluted when BOD values exceed 8 mg/L. Municipal sewage that is efficiently treated by a three-stage process would have a value of about 2...
0
Theoretical and Fundamental Chemistry
Ore deposits formed by lateral secretion are formed by metamorphic reactions during shearing, which liberate mineral constituents such as quartz, sulfides, gold, carbonates, and oxides from deforming rocks, and focus these constituents into zones of reduced pressure or dilation such as faults. This may occur without mu...
0
Theoretical and Fundamental Chemistry
A Metabolic Panel (MP) is a routine group of blood tests commonly used for health screenings, disease detection, and monitoring vital signs of hospitalized patients with specific medical conditions. MP panel analyzes common analytes in the blood to assess the functions of the kidneys and liver, as well as electrolyte a...
1
Applied and Interdisciplinary Chemistry
A dry well or drywell is an underground structure that disposes of unwanted water, most commonly surface runoff and stormwater, in some cases greywater or water used in a groundwater heat pump. It is a gravity-fed, vertical underground system that can capture surface water from impervious surfaces, then store and grad...
1
Applied and Interdisciplinary Chemistry
A hyperaccumulator is a plant capable of growing in soil or water with high concentrations of metals, absorbing these metals through their roots, and concentrating extremely high levels of metals in their tissues. The metals are concentrated at levels that are toxic to closely related species not adapted to growing on...
1
Applied and Interdisciplinary Chemistry
The distribution half-life of drospirenone is about 1.6 to 2 hours. The apparent volume of distribution of drospirenone is approximately 4 L/kg. The plasma protein binding of drospirenone is 95 to 97%. It is bound to albumin and 3 to 5% circulates freely or unbound. Drospirenone has no affinity for sex hormone-binding ...
0
Theoretical and Fundamental Chemistry
Many ketones are cyclic. The simplest class have the formula , where n varies from 2 for cyclopropanone () to the tens. Larger derivatives exist. Cyclohexanone (), a symmetrical cyclic ketone, is an important intermediate in the production of nylon. Isophorone, derived from acetone, is an unsaturated, asymmetrical keto...
0
Theoretical and Fundamental Chemistry
A clinical trial protocol is a document used to define and manage the trial. It is prepared by a panel of experts. All study investigators are expected to strictly observe the protocol. The protocol describes the scientific rationale, objective(s), design, methodology, statistical considerations and organization of the...
1
Applied and Interdisciplinary Chemistry
Across the 15th and 16th centuries there were primarily two different types of manufactured cannons. The wrought iron cannon and the cast-bronze cannon. Wrought iron guns were structurally composed of two layers: an inner tube of iron staves held together in a tight fit by an outer case of iron hoops. Bronze cannons on...
1
Applied and Interdisciplinary Chemistry
In some terminal imido complexes, the M=N−C angle is 180° but often the angle is decidedly bent. Complexes of the type M=NH are assumed to be intermediates in nitrogen fixation by synthetic catalysts.
0
Theoretical and Fundamental Chemistry
Orbiting Carbon Observatory-2 (OCO-2) is an American environmental science satellite which launched on 2 July 2014. A NASA mission, it is a replacement for the Orbiting Carbon Observatory which was lost in a launch failure in 2009. It is the second successful high-precision (better than 0.3%) observing satellite, afte...
1
Applied and Interdisciplinary Chemistry
Metal-coded affinity tag is a method used for quantitative proteomics by mass spectrometry that uses a metal chelate complex 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (DOTA) coupled to different lanthanide ions. The metal complexes attach to the cysteine residues of proteins in a sample.
0
Theoretical and Fundamental Chemistry
When two substituents are already present on the ring, the third substituent's new location is relatively predictable. If the existing substituents reinforce or the molecule is highly symmetric, there may be no ambiguity. Otherwise: # The most-activating substituent usually controls over the less-activating one. # ...
0
Theoretical and Fundamental Chemistry
The word "alkali" is derived from Arabic al qalīy (or alkali), meaning the calcined ashes (see calcination), referring to the original source of alkaline substances. A water-extract of burned plant ashes, called potash and composed mostly of potassium carbonate, was mildly basic. After heating this substance with calci...
0
Theoretical and Fundamental Chemistry
The biuret test is a chemical test for proteins and polypeptides. It is based on the biuret reagent, a blue solution that turns violet upon contact with proteins, or any substance with peptide bonds. The test and reagent do not actually contain biuret; they are so named because both biuret and proteins have the same re...
0
Theoretical and Fundamental Chemistry
In superalloys strengthened by metal carbides, increasingly large carbide particles form preferentially at grain boundaries, preventing grain boundary sliding at high temperatures. This leads to an increase in the yield strength, and thus a yield strength anomaly.
1
Applied and Interdisciplinary Chemistry
Fluoroform (CFH) has been employed as a trifluoromethylation reagent for aldehydes in combination with a strong base.
0
Theoretical and Fundamental Chemistry
Synthesis of gold nanoparticles has been investigated utilizing Fusarium, Neurospora, Verticillium, yeasts, and Aspergillus. Extracellular gold nanoparticle synthesis was demonstrated by Fusarium oxysporum, Aspergillus niger, and cytosolic extracts from Candida albican. Intracellular gold nanoparticle synthesis has be...
0
Theoretical and Fundamental Chemistry
Foodomics approach is used to analyze and establish the links between several substances presented in rosemary and the ability to cure colon cancer cells. There are thousands of chemical compounds in rosemary, but the ones that are able to help cure such disease are Carnosic acid (CA) and Carnosol (CS), which can be ob...
1
Applied and Interdisciplinary Chemistry
Lipoexpediency refers to the beneficial effects of lipids in a cell or a tissue, primarily lipid-mediated signal transmission events, that may occur even in the setting of excess fatty acids. The term was coined as an antonym to lipotoxicity.
1
Applied and Interdisciplinary Chemistry
Hypothermia has been applied therapeutically since antiquity. The Greek physician Hippocrates, the namesake of the Hippocratic Oath, advocated the packing of wounded soldiers in snow and ice. Napoleonic surgeon Baron Dominique Jean Larrey recorded that officers who were kept closer to the fire survived less often than ...
1
Applied and Interdisciplinary Chemistry