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But that was me years ago. | Cette fille c'était moi il y a quelques années. | en-fr |
And that was my first science fair project. | Và đó là đề tài khoa học đầu tiên của tôi. | en-vi |
It got a bit more complicated from there. | После стана малко по-сложно. | en-bg |
My older brother Panaki Bose spent hours of his time explaining atoms to me when I barely understood basic algebra. | 我哥哥Panaki Bose 花了很多時間在我還只會簡單代數時 跟我解釋原子。 | en-zh-tw |
My parents suffered through many more of my science fair projects, including a remote controlled garbage can. | Mijn ouders hebben nog veel meer afgezien door mijn Science Fair projecten, waaronder een op afstand te bedienen vuilnisbak. | en-nl |
(Laughter) And then came the summer after my freshman year, when my grandfather passed away due to cancer. | ♪ (смях) ♪ И тогава дойде лятото след първи курс, когато дядо ми почина от рак. | en-bg |
And I remember watching my family go through that and thinking that I never wanted another family to feel that kind of loss. | Sećam se da sam posmatrala svoju porodicu kako prolazi kroz sve to i pomislila sam kako ne želim da i jedna porodica doživi takav gubitak. | en-sr |
So, armed with all the wisdom of freshman year biology, I decided I wanted to do cancer research at 15. | Armée de toute la sagesse d’une première année d’université, j’ai décidé que je voulais faire de la recherche sur le cancer à 15 ans. | en-fr |
Good plan. | .خطة جيدة | en-ar |
So I started emailing all of these professors in my area asking to work under their supervision in a lab. | İşe mail yoluyla alanımdaki bütün profesörlere onların gözetimi altında çalışmayı talep ettiğimi ifade ederek başladım. | en-tr |
Got rejected by all except one. | همه به جز یکی منو رد کردن | en-fa |
And then went on, my next summer, to work under Dr. Basu at the UNT Health Center at Fort Worth, Texas. | و بعد، تابستون بعدی بود که رفتم تا زیر نظر دکتر باسو کار کنم در مرکز سلامت یو ان تی در فورت ورث تگزاس | en-fa |
And that is where the research began. | È qui che ha avuto inizio la ricerca. | en-it |
So ovarian cancer is one of those cancers that most people don't know about, or at least don't pay that much attention to. | О раке яичников большинство людей не знает или, по крайней мере, не обращает особого внимания. | en-ru |
But yet, it's the fifth leading cause of cancer deaths among women in the United States. | Pero, sin embargo, es la quinta causa de muerte por cáncer entre las mujeres de Estados Unidos. | en-es |
In fact, one in 70 women will be diagnosed with ovarian cancer. | U stvari, jednoj od 70 žena bit će dijagnosticiran rak ovarija. | en-hr |
One in 100 will die from it. | Una de cada 100 morirá de eso. | en-es |
Chemotherapy, one of the most effective ways used to treat cancer today, involves giving patients really high doses of chemicals to try and kill off cancer cells. | Kemoterapija, jedan od najučinkovitijih načina liječenja raka danas, uključuje davanje pacijentima vrlo visokih doza kemikalija kako bi pokušali ubiti stanice raka. | en-hr |
Cisplatin is a relatively common ovarian cancer chemotherapy drug -- a relatively simple molecule made in the lab that messes with the DNA of cancer cells and causes them to kill themselves. | سیس پلاتن یکی از دارو های نسبتا رایج برای شیمی درمانی سرطان تخمدانه یک مولکول نسبتا ساده که در آزمایشگاه ساخته میشه و با دی ان ای سلول های سرطانی رو به هم می ریزه و باعث میشه اونا خودشون رو بکشن | en-fa |
Sounds great, right? | Sună grozav, nu? | en-ro |
But here's the problem: sometimes patients become resistant to the drug, and then years after they've been declared to be cancer free, they come back. | 하지만 문제가 있습니다 때때로 환자들이 그 약에 내성이 생기고 몇년 후엔 암이 없어졌다고 진단을 받습니다, 그리고는 재발하죠. | en-ko |
And this time, they no longer respond to the drug. | A tentokrát se již léčba neprojeví. | en-cs |
It's a huge problem. | To je ogroman problem. | en-hr |
In fact, it's one of the biggest problems with chemotherapy today. | De hecho, hoy es uno de los mayores problemas de la quimioterapia. | en-es |
So we wanted to figure out how these ovarian cancer cells are becoming resistant to this drug called Cisplatin. | Chcieliśmy zbadać, jak komórki raka jajnika uodparniają się na Cisplatin. | en-pl |
And we wanted to figure this out, because if we could figure that out, then we might be able to prevent that resistance from ever happening. | Queríamos averiguar esto porque de hacerlo tal vez podríamos evitar esa resistencia. | en-es |
So that's what we set out to do. | پس این کاری بود که شروع کردیم | en-fa |
And we thought it had something to do with this protein called AMP kinase, an energy protein. | I mislili smo kako bi to moglo imati nešto s proteinom koji se naziva kinaza AMP, vrstom energetskog proteina. | en-hr |
So we ran all of these tests blocking the protein, and we saw this huge shift. | Bu proteini bloke etmek için bütün bu testleri uyguladık ve yansıda görebileceğiniz bu büyük değişimi gözlemledik. | en-tr |
I mean, on the slide, you can see that on our sensitive side, these cells that are responding to the drug, when we start blocking the protein, the number of dying cells -- those colored dots -- they're going down. | Na tomto snímku můžete vidět, že na naší straně s citlivými buňkami - tyto buňky reagují na látku, když začneme blokovat tuto bílkovinu, počet umírajících buněk - těch barevných teček - se snižuje. | en-cs |
But then on this side, with the same treatment, they're going up -- interesting. | Fakat direnç açısından, aynı işleme verilen tepki artış şeklinde oluyor --ilginç. | en-tr |
But those are dots on a screen for you; what exactly does that mean? | 그런데 여러분들이 보시는 스크린 위에 이 점들은 정확하게 무얼 뜻하는 것일까요? | en-ko |
Well basically that means that this protein is changing from the sensitive cell to the resistant cell. | In feite betekent het dat dit eiwit verandert van de gevoelige cel naar de resistente cel. | en-nl |
And in fact, it might be changing the cells themselves to make the cells resistant. | Возможно, он меняет сами клетки, делая их устойчивыми. | en-ru |
And that's huge. | Dat is enorm. | en-nl |
In fact, it means that if a patient comes in and they're resistant to this drug, then if we give them a chemical to block this protein, then we can treat them again with the same drug. | In effetti ciò significa che se a un paziente con cellule resistenti a questo farmaco gli somministriamo una sostanza che blocca questa proteina, possiamo rifare il trattamento con lo stesso farmaco. | en-it |
And that's huge for chemotherapy effectiveness -- possibly for many different types of cancer. | Und diese Erkenntnis ist unglaublich für die Effektivität von Chemotherapie, vielleicht für viele verschiedene Krebsarten. | en-de |
So that was my work, and it was my way of reimagining the future for future research, with figuring out exactly what this protein does, but also for the future of chemotherapy effectiveness -- so maybe all grandfathers with cancer have a little bit more time to spend with their grandchildren. | Das war also meine Arbeit, und so habe ich mir die Zukunft neu erdacht, wenn es um zukünftige Forschung geht, indem ich genau die Funktionsweise des Proteins entschlüssele, aber auch für die zukünftige Effektivität von Chemotherapie, also vielleicht haben alle Großväter mit Krebs dann ein bisschen mehr Zeit, die sie mi... | en-de |
But my work wasn't just about the research. | Ale má práce nebyla jen o výzkumu. | en-cs |
It was about finding my passion. | اون به معنی پیدا کردن علاقه ام بود | en-fa |
That's why being the grand prize winner of the Google Global Science Fair -- cute picture, right -- it was so exciting to me and it was such an amazing honor. | 這是身為 谷哥全球科展頭獎得主 很可愛的照片吧！ 這太令人興奮了、超棒的榮耀。 | en-zh-tw |
And ever since then, I've gotten to do some pretty cool stuff -- from getting to meet the president to getting to be on this stage to talk to all of you guys. | 從那時後開始， 我有機會做一些很酷的事， 像是跟總統見面、 站在這個舞台上 跟你們大家講話。 | en-zh-tw |
But like I said, my journey wasn't just about the research, it was about finding my passion, and it was about making my own opportunities when I didn't even know what I was doing. | Ali kao što sam rekla, moje putovanje ne predstavlja samo istraživanje, to je put pronalaženja moje strasti, i to je način kreiranja sopstvenih prilika u momentima kada čak nisam ni znala šta radim. | en-sr |
It was about inspiration and determination and never giving up on my interest for science and learning and growing. | به معنی الهام گرفتن بود و به معنی اراده و ناامید نشدن از علایقم به علم و یادگیری و رشد | en-fa |
After all, my story begins with a dried, withered spinach plant and it's only getting better from there. | 何にせよ 私の物語は しなびたホウレンソウから始まったんですから それ以上悪くなることはありません | en-ja |
(Applause) Naomi Shah: Hi everyone. I'm Naomi Shah, and today I'll be talking to you about my research involving indoor air quality and asthmatic patients. | (Applaudissements) Naomi Shah : Bonjour tout le monde. Je m’appelle Naomi Shah, et aujourd’hui je vais vous parler de mes recherches sur la qualité de l’air intérieur et les patients asthmatiques. | en-fr |
1.6 million deaths worldwide. | 1.6 milhões de morte no mundo. | en-pt-br |
One death every 20 seconds. | Jedna smrt svakih 20 sekundi. | en-hr |
People spend over 90 percent of their lives indoors. | Люди проводят в помещениях более 90% жизни. | en-ru |
And the economic burden of asthma exceeds that of HIV and tuberculosis combined. | Il costo economico dell'asma è maggiore della somma dei costi di AIDS e tubercolosi. | en-it |
Now these statistics had a huge impact on me, but what really sparked my interest in my research was watching both my dad and my brother suffer from chronic allergies year-round. | Te statystyki miały na mnie ogromny wpływ, ale co naprawdę przyciągnęło moje zainteresowanie w tych badaniach, było oglądanie mojego ojca i brata, jak przez okrągły rok cierpią na chroniczne alergie. | en-pl |
It confused me; why did these allergy symptoms persist well past the pollen season? | Es verwirrte mich, wieso hielten diese allergischen Symptome an, obwohl die Pollensaison vorbei war? | en-de |
With this question in mind, I started researching, and I soon found that indoor air pollutants were the culprit. | Met deze vraag in het achterhoofd, begon ik met mijn onderzoek. Ik ontdekte al snel dat de luchtvervuilende stoffen binnenshuis de boosdoener waren. | en-nl |
As soon as I realized this, I investigated the underlying relationship between four prevalent air pollutants and their affect on the lung health of asthmatic patients. | 이걸 알아 내자 마자, 저는 근본적인 관계를 조사했습니다 네개의 일반적인 공기 오염물질과 천식환자들의 폐건강에 대한 영향 사이의 관계말이죠. | en-ko |
At first, I just wanted to figure out which of these four pollutants have the largest negative health impact on the lung health of asthmatic patients. | 一開始，我只是想要知道 這四種污染物哪一種 對氣喘病患的健康負面影響最大。 | en-zh-tw |
But soon after, I developed a novel mathematical model that essentially quantifies the effect of these environmental pollutants on the lung health of asthmatic patients. | No uskoro sam razvila novi matematički model koji u osnovi kvantificira učinak tih okolišnih onečišćivača na zdravlje pluća astmatičara. | en-hr |
And it surprises me that no model currently exists that quantifies the effect of environmental factors on human lung health, because that relationship seems so important. | A překvapuje mě, že v současnosti neexistuje žádný model, který by kvantifikoval dopad faktorů životního prostředí na zdraví lidských plic, protože mi tento vztah připadá dost důležitý. | en-cs |
So with that in mind, I started researching more, I started investigating more, and I became very passionate. | Então com isso na mente, comecei pesquisando mais, comecei investigando mais, e me apaixonei. | en-pt-br |
Because I realized that if we could find a way to target remediation, we could also find a way to treat asthmatic patients more effectively. | Parce que je me suis rendue compte que si nous pouvons trouver un moyen de cibler un traitement, nous pouvons aussi trouver un moyen de traiter les patients asthmatiques plus efficacement. | en-fr |
For example, volatile organic compounds are chemical pollutants that are found in our schools, homes and workplaces. | לדוגמה, תרכובות אורגניות נדיפות הם מזהמים כימיים שנמצאים בבתי הספר שלנו, בבתינו ובמקומות העבודה. | en-he |
They're everywhere. | Chúng ở khắp mọi nơi. | en-vi |
These chemical pollutants are currently not a criteria air pollutant, as defined by the U.S. Clean Air Act. | Te zanieczyszczenia chemiczne nie są obecnie zdefiniowanymi zanieczyszczeniami powietrza, zgodnie z amerykańską Ustawą o Czystym Powietrzu (U.S. Clean Air Act) | en-pl |
Which is surprising to me, because these chemical pollutants, through my research, I show that they had a very large negative impact on the lung health of asthmatic patients and thus should be regulated. | O que me surpreende, dado que estes poluentes químicos, como mostro na minha investigação, tiveram um grande impacto negativo na saúde pulmonar dos doentes asmáticos e portanto deviam ser regulamentados. | en-pt |
So today I want to show you my interactive software model that I created. | Takže dnes vám chci ukázat můj interaktivní model, který jsem vytvořila. | en-cs |
I'm going to show it to you on my laptop. | Ich werde es euch auf meinem Laptop zeigen. | en-de |
And I have a volunteer subject in the audience today, Julie. | И в аудитории есть доброволец, Джули. | en-ru |
And all of Julie's data has been pre-entered into my interactive software model. | 私のソフトウェアにジュリーのデータを あらかじめ入力してあります | en-ja |
And this can be used by anyone. | و هر کسی می تونه ازش استفاده کنه | en-fa |
So I want you to imagine that you're in Julie's shoes, or someone who's really close to you who suffers from asthma or another lung disorder. | 여러분이 줄리나 여러분께 매우 가까운 사람의 입장에 처해 있다고 생각해 보세요, 천식이나 폐질환을 겪고 있는 사람들말이에요. | en-ko |
So Julie's going to her doctor's office to get treated for her asthma. | Džuli odlazi kod svog lekara kako bi dobila lek za astmu. | en-sr |
And the doctor has her sit down, and he takes her peak expiratory flow rate -- which is essentially her exhalation rate, or the amount of air that she can breathe out in one breath. | و دکتر به او میگه بشین و حداکثر شدت جریان تنفسی او رو اندازه گیری می کنه که همون سرعت بازدم او هست یا میزان هوایی که می تونه در یک بازدم بیرون بده | en-fa |
So that peak expiratory flow rate, I've entered it up into the interactive software model. | قمت بإدخال معدّل ذروة التدفق الزفيري هذا .في نموذج البرنامج التفاعلي | en-ar |
I've also entered in her age, her gender and her height. | Também inseri sua idade, sexo e altura. | en-pt-br |
I've assumed that she lives in an average household with average air pollutant levels. | Предположих, че живее в средно домакинство със средни нива на замърсители на въздуха. | en-bg |
So any user can come in here and click on "lung function report" and it'll take them to this report that I created. | فأي مستخدم قد يأتي إلى هنا "و ينقر على زر " تقرير وظيفة الرئة .و سأنقل البيانات إلى هذا التقرير الذي قمت بإنشائه | en-ar |
And this report really drives home the crux of my research. | 이 리포트는 제 연구의 가장 중요한 부분을 이해하게 만들어줍니다 | en-ko |
So what it shows -- if you want to focus on that top graph in the right-hand corner -- it shows Julie's actual peak expiratory flow rate in the yellow bar. | Peki rapor ne gösteriyor? --Sağ üst köşedeki grafiğe bakacak olursanız-- sarı renk ile gösterilen bölgede Julie'nin gerçek nefes verme gücü gösteriliyor. | en-tr |
This is the measurement that she took in her doctor's office. | De meting uit het kabinet van haar arts. | en-nl |
In the blue bar at the bottom of the graph, it shows what her peak expiratory flow rate, what her exhalation rate or lung health, should be based on her age, gender and height. | בפס הכחול בתחתית הגרף, רואים מה שיא קצב הנשיפה שלה, מה קצב הנשימה שלה או בריאות הריאה צריכים להיות בהתבסס על הגיל, המין והגובה שלה. | en-he |
So the doctor sees this difference between the yellow bar and the blue bar, and he says, "Wow, we need to give her steroids, medication and inhalers." | Doktor sarı ve mavi bar arasındaki farkı görüyor ve "Vay canına, Julie'ye steroid, ilaç ve sprey vermeliyiz." | en-tr |
But I want everyone here to reimagine a world where instead of prescribing steroids, inhalers and medication, the doctor turns to Julie and says, "Why don't you go home and clean out your air filters. | Želim da svi zamislite svet u kom će, umesto prepisivanja steroida, inhalatora i lekova, doktor reći Džuli sledeće: "Zašto ne biste otišli kući i zamenili filtere za vazduh. | en-sr |
Clean out the air ducts in your home, in your workplace, in your school. | 家や職場や学校の エアダクトを掃除して | en-ja |
Stop the use of incense and candles. | Smetti di usare incensi e candele. | en-it |
And if you're remodeling your house, take out all the carpeting and put in hardwood flooring." | A pokud přestavuješ dům, odstraň všechny koberce a pořiď si dřevěnou podlahu." | en-cs |
Because these solutions are natural, these solutions are sustainable, and these solutions are long-term investments -- long-term investments that we're making for our generation and for future generations. | Protože tato řešení jsou přirozená, tato řešení jsou udržitelná, a tato řešení jsou dlouhodobou investicí - dlouhodobou investicí, kterou děláme pro naši generaci a pro generace budoucí. | en-cs |
Because these environmental solutions that Julie can make in her home, her workplace and her school are impacting everyone that lives around her. | Denn diese Umweltlösungen, die Julie in ihrem Zuhause, auf ihrer Arbeit und in ihrer Schule umsetzen kann, betreffen alle, die in ihrem Umfeld leben. | en-de |
So I'm very passionate about this research and I really want to continue it and expand it to more disorders besides asthma, more respiratory disorders, as well as more pollutants. | 所以我对这项研究非常热情 我非常希望能够继续研究 将它扩展到除了哮喘病之外的更多的疾病， 更多的呼吸系统疾病，以及更多的污染物 | en-zh-cn |
But before I end my talk today, I want to leave you with one saying. | Dar înainte să-mi închei prezentarea de astăzi vreau să plec lăsându-vă cu o vorbă, | en-ro |
And that saying is that genetics loads the gun, but the environment pulls the trigger. | La massima secondo cui la genetica carica la pistola, ma è l'ambiente a premere il grilletto. | en-it |
And that made a huge impact on me when I was doing this research. | וזה השפיע עלי מאוד כשעשיתי את המחקר. | en-he |
Because what I feel, is a lot of us think that the environment is at a macro level, that we can't do anything to change our air quality or to change the climate or anything. | Bởi vì điều mà tôi cảm thấy, là rất nhiều người trong chúng ta nghĩ rằng môi trường nằm ở một mức vĩ mô, mà chúng ta không thể làm gì để thay đổi chất lượng không khí hay thay đổi khí hậu hay bất cứ cái gì. | en-vi |
But if each one of us takes initiative in our own home, in our own school and in our own workplace, we can make a huge difference in air quality. | 하지만 우리 각자가 자기의 가정에서 학교에서 직장에서 시작한다면 우리는 대기의 질에 큰 변화를 가져올 수 있습니다. | en-ko |
Because remember, we spend 90 percent of our lives indoors. | .لأننا نقضي 90% من حياتنا في الأماكن المغلقة | en-ar |
And air quality and air pollutants have a huge impact on the lung health of asthmatic patients, anyone with a respiratory disorder and really all of us in general. | و جودة الهواء و ملوثات الهواء ,لها تأثير كبير على صحة الرئة عند مرضى الربو و على أي أحد يعاني من اضطراب في جهازه التنفسي .و بالتأكيد يؤثر علينا جميعاً بشكلٍ عام | en-ar |
So I want you to reimagine a world with better air quality, better quality of life and better quality of living for everyone including our future generations. | پس از شما می خوام که دنیایی رو در ذهنتون بازسازی کنید که در اون کیفیت هوا بهتر باشه کیفیت زندگی بیشتر باشه و کیفیت معاش برای تک تک ما و همچنین نسل های آینده مون بیشتر باشه | en-fa |
(Applause) Lisa Ling: Right. | (Aplausos) Lisa Ling: Certo. | en-pt-br |
Can I have Shree and Lauren come up really quickly? | Shree và Lauren nhanh lên đây được không? | en-vi |
Your Google Science Fair champions. | Suas campeãs da Feira de Ciências do Google. | en-pt-br |
Your winners. | .أنتن رابحات | en-ar |
Amongst all the troubling deficits we struggle with today -- we think of financial and economic primarily -- the ones that concern me most is the deficit of political dialogue -- our ability to address modern conflicts as they are, to go to the source of what they're all about and to understand the key players and to d... | Wśród problemów z jakimi zmagamy się dziś, mamy na myśli przede wszystkim te finansowe i ekonomiczne. Problemem, który mnie interesuje najbardziej jest deficyt politycznego dialogu, brak umiejętności odniesienia się do współczesnych konfliktów, dotarcia do ich źródła i zrozumienia kim są ich kluczowi gracze i jak z nim... | en-pl |
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