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Predictive genetic testing is now routinely offered to asymptomatic adults at risk for genetic disease. However, testing of minors at risk for adult-onset conditions, where no treatment or preventive intervention exists, has evoked greater controversy and inspired a debate spanning two decades. This review aims to prov... |
Hidradenitis suppurativa (HS) is a chronic and debilitating suppurative disease primarily affecting the axillae, perineum, and inframammary regions, where apocrine sweat glands are present. However, HS can occur in atypical locations. We present an interesting case of a 40-year-old man who developed chronic painful sub... |
PurposeThis study aims to determine the effects of consumers' perceptions of value and environmental concerns toward recycled content clothing on consumers' attitudes and purchase intentions toward these products.Design/methodology/approachThe research methodology consisted of consumer survey. Female consumers register... |
Miller-Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS) and is characterized by the clinical triad of ataxia, ophthalmoplegia, and areflexia. The incidence rate in Thailand has not been established but it occurred approximately 1-5% that of GBS. Here, the authors report a Thai patient diagnosed ... |
This article presents a comparison of damage accumulation calculations performed according to the Palmgren-Miner linear damage hypothesis and a new nonlinear damage accumulation aggregation hypothesis based on material memory for completed experimental block tests of 6082-T6 aluminum alloy. Block loads represent operat... |
The need for high lateral spatial resolution in thermal science using Scanning Thermal Microscopy (SThM) has pushed researchers to look for more and more tiny probes. SThM probes have consequently become more and more sensitive to the size effects that occur within the probe, the sample, and their interaction. Reducing... |
In this paper we describe a functioning low cost embedded vision system which can perform basic color blob tracking at 16.7 frames per second. This system utilizes a low cost CMOS color camera module and all image data is processed by a high speed, low cost microcontroller. This eliminates the need for a separate frame... |
The price of eternal vigilance is indifference. —Marshall McLuhan, Understanding Media (30) Here in Sarajevo, hundreds of TV crews parade before our very eyes; dozens of foreign journalists, reporters, and writers. Everything is known here, right down to minutest details, and yet, nothing … —Jean Marie Cardinal Lustige... |
A numerical heat transfer model for predicting product temperature profiles during high‐pressure thawing processes was recently proposed by the authors. In the present work, the predictive capacity of the model was considerably improved by taking into account the pressure dependence of the latent heat of the product th... |
Stroke is the leading cause of disability worldwide. Traditionally, doctors assess stroke rehabilitation assessment, which can be subjective. Therefore, an objective assessment method is required. In this context, we investigated the changes in brain functional connectivity patterns and corticomuscular coupling in stro... |
The paper presents the results of studies of a coaxial gun for a plasma-filled electron diode. Effects of the discharge channel diameter and gun current on characteristics of the plasma and pulse generated in the diode were investigated. The electron beam with maximum energy of ≥1 MeV at the current of ≈100 kA was obta... |
The aim of this workshop is to promote discussion and collaboration among educational practitioners and researchers, and others with an interest in using new technologies to stimulate learners' interest and motivation in science topics, and to explore ways in which emerging technologies can be appropriated for use in s... |
AIM |
To analyze the expression of bone morphogenetic proteins (BMPs) in prostate and breast cancers with established metastasis in bone, where prostate cancer causes osteoblastic metastases, and breast cancer osteolytic metastases. |
METHODS |
Primary tumor specimens from 20 patients with prostate cancer and 15 with breast cancer were studied for BMP-2/4, -3, -5, -6 and -7 immunohistochemistry. All patients had multiple bone metastases proven by bone scan. We also examined BMPs expression in normal prostate and breast tissues. BMPs expression was compared wi... |
RESULTS |
Cytoplasmic BMPs immunostaining was observed in both prostate cancer and normal prostate tissue. Expression of BMP-2/4, -5, -6, and -7 proteins was detected in all normal prostate samples, with the predominance of BMP-2/4 (87.8-/+11.4% positive cells) and BMP-7 (94.6-/+0.9% positive cells). In prostate cancer tissues, ... |
CONCLUSION |
The expression of BMPs differs between prostate and breast cancer cells. Identifying the BMP proteins in cancers may be useful for monitoring the tumor status with reference to metastases.5-Hydroxytryptamine extraction by the lung. |
Both 5-hydroxytryptamine and norepinephrine are removed from blood during a single passage through the pulmonary vasculature of the dog; 5-hydroxytryptamine is removed to a greater degree than is norepinephrine. The magnitude of extraction of both 5-hydroxytryptamine and norepinephrine is similar to that previously det... |
A 3-year prospective follow-up investigation and a family study were carried out in patients fulfilling the diagnostic criteria for cycloid psychotic disorder proposed by Perris and Brockington in 1981. The results show that cycloid psychosis differs in several respects from schizoaffective disorders as defined by curr... |
This study aims at identifying the factors affecting the intention to use personal digital assistant (PDA) technology among physicians in Turkey using an extended Technology Acceptance Model (TAM). A structural equation-modeling approach was used to identify the variables that significantly affect the intention to use ... |
In this paper, a fast algorithm for radar detection based on line Hough transform is presented. Unlike the traditional method, the idea of our proposed is that the point of data space should be mapped into the Hough parameter space of slope and intercept, where the relative position of the points in the data space is p... |
In this article we introduce a novel motion estimation method for video sequences. Proposed method can be employed as a part of video encoders, and decoders to increase the compression ratio, and decrease the temporal redundancies. In the presented method, first a global motion vector is computed for each frame, by use... |
The opportunistic cervical cancer screening has been conducted in Croatia since its introduction in the 1960s, in the context of a high quality gynaecological cytology with a long tradition and a wide network of primary care gynaecologists. In 2006, a pilot screening programme under the title "Early detection of cervic... |
Two-dimensional (2D) symmetric flapping flight is investigated by an immersed boundary-lattice Boltzmann method (IB-LBM). In this method, we can treat the moving boundary problem efficiently on the Cartesian grid. We consider a model consisting of 2D symmetric flapping wings without mass connected by a hinge with mass.... |
Background Gallium 68-labeled fibroblast-activation protein inhibitor (68Ga-FAPI), an imaging agent for detecting tumors, represents a promising alternative to fluorine 18 fluorodeoxyglucose (18F-FDG). Purpose To compare the potential efficacy of 68Ga-FAPI PET/CT with that of 18F-FDG PET/CT for detecting primary tumor ... |
Provides a brief overview of a unified technique, called fragmented data processing (FDP), for jointly improving the reliability and security with which distributed computing systems process sensitive information. This technique has already been used to implement various system services in the DELTA-4 distributed syste... |
The mechanism and chemoselectivity in the cycloaddition of ynamides and isoxazoles have been explored by the density functional theory (DFT) in model systems composed of a Bronsted acid (HNTf2), gold(I) [IPrAuNTf2] or platinum(II) (PtCl2/CO) catalyst, either with or without the presence of H2O. The DFT calculations rev... |
Lymphoma is the most common malignancy involving the mediastinum but can be challenging to diagnose on small biopsy specimens. This review provides a pattern-based approach to help triage small tissue samples for the diagnosis of mediastinal lymphoid proliferations, with focus on the main primary mediastinal lymphomas.... |
The impact of the availability of technology-enabled digital goods on the sales of the physical counterpart faces uncertainty in the electronic commerce domain. We address the issue empirically by identifying the effect of the availability of digitally-delivered movies on physical DVD movie sales. Unique to our study i... |
OBJECTIVE |
To construct the ovexpression lentivirus vector of PPP2Cβ, the catalytic subunit of protein phosphatase 2A, so as to obtain high-titer packaged lentivirus particles, and to examine the effect of PPP2Cβ on the erythroid differentiation Methods: The CDS of PPP2Cβ was cloned into the second generation of lentivirus vector... |
RESULTS |
The PPP2Cβ overexpressing lentivirus vectors were constructed, the high-titer lentiviral particles were obtained, and then the PPP2Cβ overexpression K562 cell line was established and promote erythroid differentiation of K562 cells. |
CONCLUSION |
This study suggests that overexpression PPP2Cβ can promote K562 cell erythroid differentiation.Editorial: Ecosystem and Hydrological Responses in Mountain Environments to the Changing Climate |
Worldwide the resilience of mountain ecosystems to transient changes in climate and anthropogenic footprint has been reduced (Schirpke et al., 2017; Chettri et al., 2020). The reduced resilience has a direct impact on the sustenance of the biotic and abiotic resources that include snow, glaciers, permafrost, soils, for... |
Mukithreaded processors are an attractive alternative to superscalar processors. Their ability to handle multiple threads simultaneously is likely to result in higher instruction throughput andinbetter utilization of functional units, though they can still benefit from many (hardware and software) functionalities of su... |
The BMA and the NHS Alliance have questioned the value of the latest idea from the prime minister for all general practitioners in England to undergo the “friends and family” test as a way to root out services that offer unacceptable standards of care. |
Last May the government announced that hospitals in England would be subject to the test from this April after a recommendation from the Nursing Quality Care Forum, which was set up last January after a number of high profile cases of poor care in the NHS.1 |
But on 4 January David Cameron said that the test, in which patients and staff are asked …Small-Group Affective Curriculum for Gifted Students: A Longitudinal Study of Teacher-Facilitators |
A longitudinal study of the implementation of a small-group affective curriculum involved Grades 5–8 in a school for gifted children. Teacher-facilitators' perceptions were of interest. Over time, significant positive change occurred for items related to the perceived need for an affective curriculum, impact on the sch... |
introDUCtion The history of task analysis is nearly a century old, with its roots in the work of Gilbreth (1911) and Taylor (1912). Taylor's scientific management provided the theoretical basis for production-line manufacturing. The ancient manufacturing approach using craft skill involved an individual, or a small gro... |
Oxyanions of arsenic and selenium can be used in microbial anaerobic respiration as terminal electron acceptors. The detection of arsenate and selenate respiring bacteria in numerous pristine and contaminated environments and their rapid appearance in enrichment culture suggest that they are widespread and metabolicall... |
As reported in a recent article in the Journal, Joseph and Isaacs (1) tried to combine Linomide® with other antiangiogenic agents known to inhibit tumorassociated macrophages (TAMs) to evaluate their joint antitumor effects. Unfortunately, the combination of Linomide with other antiangiogenic agents did not result in p... |
The publication is intended for undergraduate students taking courses of Chemical Technology and Engineering in English at the Faculty of Chemical Technology. The aim of the publication is to help students prepare for laboratory works in inorganic chemistry, carry out the work according to the outlined methodologies, a... |
Background There is limited evidence regarding seroprevalence during the first wave of COVID-19 in Thailand. The limited capacity of molecular laboratories in distant provinces may have resulted in fewer confirmed COVID-19 cases and possible undetected ongoing transmission, as suggested by a previously published seropr... |
We summarize the object-based virtualization model that we have been developing for the past decade, and demonstrate how it enables automatic optimizations, especially at runtime. The parallel programming paradigm represented by the virtualization model has been implemented in the Charm++ and AMPI libraries. In this pa... |
The Conscientious Responders Scale is a five-item embeddable validity scale that differentiates between conscientious and indiscriminate responding in personality-questionnaire data (CR & IR). This investigation presents further evidence of its validity and generalizability across two experiments. Study 1 tests its sen... |
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