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The death pace of Myocardial Infarction is high throughout the world. The sickness happens because of the blockage of coronary arteries supply in the heart. Almost half of the individuals die before arriving at the clinic, and the recovery turns out to be problematic when the patient gets a second or third attack befor... |
A palladium/copper-cocatalyzed Ullmann-type N-arylation of anilines using alkyl(aryl)sulfonium triflates as arylation reagents has been accomplished. The reaction enabled Caryl-S bond cleavage over Calkyl-S bond breakage of alkyl(aryl)sulfoniums by Pd(P(tBu)3)2/CuI and gave the corresponding N-arylated products in good... |
The central focus of this paper was to determine whether there was a consensus for the concept of mental health. Therapists from different professional orientations in a United States sample rank ordered their views of the optimally integrated person using a 20-paragraph personality questionnaire based on Murray's need... |
With ever-rising heat dissipation in electronics, there has been considerable research into liquid-cooled systems. Intermittent spray cooling (ISC) is one of the novel and efficient ways to cool the IC chip. In this article, a sequential function specification method is applied to the experimentally measured data, to d... |
This commentary invites readers to consider the merits of approaching administrative ethics in constitutional terms. Relying on his familiarity with French and American constitutional traditions, the author provides a concrete example of constitutionally based ethics in a comparative context. Following Tocqueville's ad... |
In after-death communication (ADC), a living individual experiences direct contact with a deceased entity. Research has shown such experiences to be common and overwhelmingly beneficial. However, clients in counseling—particularly conservative Christian clients—have expressed reluctance, distress, rejection, and/or avo... |
Depletion of peroxisome proliferator-activated receptor gamma (PPARgamma) represents one of the key molecular changes that underlie transdifferentiation (activation) of hepatic stellate cells in the genesis of liver fibrosis (Miyahara, T., Schrum, L., Rippe, R., Xiong, S., Yee, H. F., Jr., Motomura, K., Anania, F. A., ... |
Introduction: The existence of an aqueous ocean, the interactions between the ice crust and liquid, chemical characterization of the surface, and search fo r bi traces of a pre, or still existing life are some of the important scientific objectives of the upcoming missi on(s) to Europa. Many of these objectives maybe a... |
The evaluation of elastic property for thin diamond-like carbon (DLC) films has been presented with buckle analysis of compressive stressed film on patterned substrate. When substrate has been patterned with adhesion release layer, the morphologies of buckle configuration on patterned layer has been controlled from str... |
Doublesex (DSX) is a transcription factor in Drosophila melanogaster that regulates somatic sexual differentiation. Homologues have been found in diverse metazoans, suggesting a conserved role in development. Here, the expression, purification and crystallization of a novel 63-amino-acid dimerization domain and selenom... |
The paper presents a strong and realistic model for induction motors including space harmonics of magnetic induction in the sinusoidal distribution model under inter-turn short circuits faults. To represent as much as possible, the reality of the asynchronous machine, we include space harmonics of magnetic induction in... |
Given the Portuguese national programme for rehabilitation of school buildings and the new regulations for thermal comfort and air quality in Portugal, whose demands contribute to increase energy costs, it became relevant to study a case before any refurbishment intervention, in order to assess the potential of differe... |
Although drug companies spend billions of dollars on marketing their products and have been successful in influencing doctors' prescribing decisions, a new study shows that only a small proportion of medical residency programmes in the United States teach doctors how to deal with such pressures ( Academic Medicine 2004... |
Dr Raquel Watkins, lead author of the study and assistant professor of internal medicine at Wake Forest University Baptist Medical …Summarizing a new approach to design speech recognition systems: a reliable noise-immune HW-SW version |
Presents in this paper a summary of a new approach aimed at coupling "HW/SW codesign" with "redundancy techniques" to implement speech recognition systems (SRS). The methodology partitions the HW and SW parts in such a way as to boost system performance while area overhead is maintained as low as possible. At the same ... |
Nowadays research of psychomotor actions has taken a special place in education, sports, medicine, psychology etc. Development of computer system for psychomotor testing could help solve many operational problems in psychoneurology and psychophysiology and also determine the individual characteristics of fine motor ski... |
The composition and thickness of thin films determine their physical properties, making the ability to measure the number of atoms of different elements in films both technologically and scientifically important. For thin films, below a certain thickness, the X-ray fluorescence intensity of an element is proportional t... |
The results obtained in reviewing series of 236 patients suffering from upper digestive haemorrhages and observed in a close to 10 years period are reported. Some data regarding the age and sex of patients, the frequency of the condition at certain periods of the year and the type of lesion that led to bleeding are rev... |
Broadcast service is widely used during the life time of a wireless sensor network (WSN), such as networking setup, data collection/storage and query answering. In the past few years, many works have been done to improve its efficiency by reducing redundant broadcast messages. However, most of these works assume that a... |
When a disruption occurs in a firm, its effects are often felt throughout the supply chain. As supply chains expand globally and companies pursue velocity and efficiency, the probability of disruptions propagating throughout a chain grows. In this paper, we employ a qualitative, grounded theory case study approach to h... |
This article rationalises the case law of the European Court of Human Rights under Article 8 of the European Convention on Human Rights in deportation cases involving children. The Court engages in a balancing exercise between the right to family life of the deportee’s family on the one side, and the public interest i... |
Emerging white-light LEDs allow the combination of illumination and optical wireless communication in one optical source. Visible light communication (VLC) uses solid-state LEDs to broadcast information and is an attractive technology for indoor positioning system. In this paper, we propose a higher accuracy indoor pos... |
A new form of acute hepatic porphyria with double genetic defect--deficiency of porphobilinogen deaminase and coproporphyrinogen oxidase--is described. Among 17 studied family members this double enzymatic deficiency was found in five individuals, deficiency of porphobilinogen deaminase in four, and deficiency of copro... |
BACKGROUND |
Human papillomavirus (HPV) has emerged as a causative agent and positive prognostic factor for oropharyngeal (OP) head and neck squamous cell cancer (HNSCC). This prompts inquiry into whether therapy improvements or increasing incidence of HPV drives the apparent improvements in HNSCC outcomes observed in non-randomize... |
PATIENTS AND METHODS |
We reviewed all locoregionally advanced HNSCC patients treated with chemotherapy and radiation in prospective institutional trials at a single institution. Patients were divided into three groups (1, 2, 3) according to treatment time period (1993-1998, 1999-2003, 2004-2010, respectively). We reasoned that if a favorabl... |
RESULTS |
Four hundred and twenty-two patients were identified with OP (55.7%) and non-OP (44.3%) HNSCC. Five-year OP overall survival (OS) improved from 42.3% (group 1) to 72.5% (group 2), and 78.4% (group 3), adjusted P = 0.0084. Non-OP 5-year OS was 51.0% (group 1), 58.8% (group 2), and 66.3% (group 3), adjusted P = 0.51. Fiv... |
CONCLUSIONS |
Over the past two decades, OP HNSCC outcomes improved significantly, while non-OP outcomes only trended toward improvement. Although our patients are not stratified by HPV status, improving OP outcomes are likely at least partly due to the increasing HPV incidence. These data further justify trial stratification by HPV... |
A nonlinear analysis of coupled-oscillator systems under modulated inputs is presented. Angle modulation is introduced to the array by injection locking one of the oscillators to an external modulated reference signal. Envelope transient analysis is used to investigate the effect of the modulation versus scanning angle... |
Cardiopulmonary function and power as well as efficient motion skill are extremely important for athletes. Thanks to the latest sensing technology and smart devices, many researchers have focused on sports-skill analysis. Electromyography (EMG), in particular, is gaining attention as a method of understanding the power... |
Game assets such as characters, currencies and items are increasingly being traded for real money. Game operators have reacted in various ways: some attempt to curtail the trade, while others encourage it. A growing number are getting involved in the trade themselves. In this paper I develop a classification based on m... |
We present the first measurements of the lightning return stroke speed that directly relate to the current return stroke, as opposed to its optical manifestation. The shape of elves is determined by the electromagnetic pulse (EMP) radiation pattern at D region altitudes, which is in turn controlled by the geometry and ... |
AIM |
To compare the gene expression profile in a pair of HBV-infected twins. |
METHODS |
The gene expression profile was compared in a pair of HBV-infected twins. |
RESULTS |
The twins displayed different disease outcomes. One acquired natural immunity against HBV, whereas the other became a chronic HBV carrier. Eighty-eight and forty-six genes were found to be up- or down-regulated in their PBMCs, respectively. Tumor necrosis factor-alpha-induced protein 1 (TNF-alphaIP1) that expressed at ... |
CONCLUSION |
TNF-alphaIP1 may play a role in the innate immunity against HBV.Development Impacts of Value Chain Interventions: How to Collect Credible Evidence and Draw Valid Conclusions in Impact Evaluations? |
In development policy and practice, support to or interventions in value chains are considered to be instrumental for achieving outcomes such as poverty alleviation. This paper reviews methodological discussions on how to show the effects and workings of value chain support in a context of donors demanding rigorous imp... |
It is currently a very active research area to develop new types of substrates which integrate various nanomaterials for surface-enhanced Raman scattering (SERS) techniques. Here we report a unique approach to prepare SERS substrates with reproducible performance. It features silicon mold-assisted magnetic assembling o... |
1. Urine was the major route of excretion of radioactivity (95% dose in 0-24 h) following the oral, intravenous or intraperitoneal administration of [14C]-trimethylamine N-oxide dihydrate (1 mmol/kg body wt) to the adult male Wistar rat. A further 3-4% was voided in the urine during 24-72 h. Only fractional amounts wer... |
Calcification of intervertebral discs is a rare occurrence in children. Although the etiology of the calcification remains uncertain, it is no related with degenerative diseases. The clinical picture is non specific with neck pain, muscle contractures and, sometimes, low-grade fever. These symptoms generally disappear ... |
In the United States, millions of Americans are affected by chronic pain, which adds heavily to national rates of morbidity, mortality, and disability, with an ever-increasing prevalence. According to a 2011 report titled Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research ... |
This paper studies user-specific clustering for a downlink cloud radio access network (C-RAN), where a central unit (CU), connected to all base stations (BSs) via limited-capacity backhaul links, coordinates the BSs to form cooperative clusters for every user. By taking into account the training overhead for channel es... |
Particle interaction is a critical parameter for growth kinetics of colloidal crystals. The equilibrium concentration and step free energy are strongly dependent on the particle interaction. The growth mechanism of the attractive system of colloidal crystals is similar to that of vapor or solution growth, where crystal... |
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