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Background: Psychiatric emergencies are characterized by acute conditions of disturbances of affect or mood, behaviour, and thoughts, if not managed with immediate therapeutic intervention can cause great harm to the patient and surroundings. In most of the institutions due to lack of emergency psychiatric units, these... |
This chapter reports on ‘Troubled Families’ in Greater Manchester, a sub-regional implementation of a controversial national programme in England intended to offer joined-up services targeted at families representing the highest costs to the public purse. Its underpinning principles include early intervention with chil... |
The cDNA encoding human Vascular Endothelial Growth Factor 165 (VEGF165) was amplified using RT-PCR from human tonsil tissue and cloned into eukaryotic expression vector pcDNA3.1 (+). The recombinant plasmid pcDNA/V was transferred into 293 cells mediated by liposome and the cells stably expressing VEGF were selected u... |
This issue of the NIJ Journal discusses three diverse topics— Russian organized crime, the Federal role in Indian Country justice, and pathological gambling. In the cover story, Distinguished Professor James O. Finckenauer and Elin Waring report the findings of a 4-year investigation into the operations of the Russian ... |
Using molecular dynamics simulations, we study freezing of Lennard-Jones particles at commensurate substrate with triangular pattern. Throughout the box particles freeze onto the substrate and form close-packed layers. For the moderately attractive substrates, an intermediate hexatic phase between liquid and crystal is... |
In distributed systems, trust decisions are often based on remote attestations in which evidence is gathered about the integrity of subcomponents. Layered attestations leverage hierarchical dependencies among the subcomponents to bolster the trustworthiness of evidence. Copland is a declarative, domain-specific languag... |
Emotions have a direct influence on an individual's physical and cognitive behaviour, as well as their performance, a student with a positive emotional state will learn and perform better. This paper presents an agent framework that addresses the relationship between user's state of emotion during learning and the modi... |
High enthalpy short-duration facilities are mainly used to simulate the hypersonic flow during a reentry into an atmosphere. The special operational features of these facilities put somewhat different requirements on the instrumentation compared to usual supersonic or hypersonic blow down tunnels. The short running tim... |
Biochemical recurrence (BCR) occurs up to 40% of men who had radical prostatectomy for localized prostate cancer. Regional nodes are usually involved in these cases. Salvage lymphadenectomy (sLND) has been advocated in patients with 'node-only' metastasis with biochemical recurrence, following a definitive treatment of... |
For modelling purposes, complex technical processes are frequently broken down into elementary sub-processes, which are subsequently simulated with different programs and methods. This can only be done effectively if the individual programs are linked in terms of their contents. In order to create programs and program ... |
In this article we present an automatic approach to extracting Hindi-English (H-E) Named Entity (NE) translingual equivalences from bilingual parallel corpora. In the absence of a Hindi NE tagger or H-E translation dictionary, this approach adapts a Chinese-English (C-E) surface string transliteration model for H-E NE ... |
In society's effort to address and prepare for climate change, the health community itself must ensure that it is prepared. Health personnel will require flexible and iterative action plans to address climate change at the individual, hospital, local health department, state, and national levels. This requires that hea... |
The 2021 guidelines of the European Society of Cardiology for the diagnosis and treatment of heart failure recommend the early implementation of all four mortality-lowering drug classes for heart failure with reduced ejection fraction (HFrEF), i. e. angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor... |
Early detection of adventitious lung sounds in pediatric population is of prime importance as untreated respiratory disorders can become chronic and non-curable in adulthood. This study deals with application of signal processing methods to preliminary classify normal and adventitious lung sounds of children using elec... |
An excitation function for LPC synthesis is constructed from a best estimate of the glottal volume velocity waveform. By proper smoothing, inverse filtering, and truncation, the phase characteristics of the glottal wave are preserved, while the basic requirement of an essentially flat spectrum is also satisfied. The ne... |
The objective of this paper is a brief introduction in the doctoral thesis of the author. The content of the thesis is the design of the structure for efficient management of the public administration. The author explores the options, how to combine the Enterprise Architecture elements with the business process managem... |
The COBOL component in four-year computer information systems programs is crucial to the rest of the program, and should be handled with special care. Particularly in CIS programs modeled after ACM's recommendations for computer information systems, students who have become reasonably proficient in a high level program... |
BACKGROUND |
B-domain-deleted recombinant factor VIII (BDDrFVIII) was developed when the B-domain was found to be redundant for maintaining haemostasis. This allows formulation of the final product without albumin added as a stabilizer. |
METHODS |
Three multicentre clinical studies and one pharmacokinetic study were conducted in 218 patients to evaluate the safety and haemostatic efficacy of BDDrFVIII. |
RESULTS |
Previously treated patients (n = 113; median duration, 1711 days; median exposure days, 385; total 98,096,287 IU infused) rated 97-99% of all infusions as good or excellent efficacy. FVIII inhibitor was noted in one patient in the previously treated patient cohort after 113 exposure days. Among 101 previously untreated... |
CONCLUSIONS |
The results of these clinical studies indicate that BBDrFVIII is safe and effective and has haemostatic activity similar to that of full-length FVIII concentrates.Short communication: effectiveness of sample duplication to control error in ruminant digestion studies. |
Eight ruminally cannulated lactating dairy cows from a study on the effect of dietary rumen-degraded protein on production and digestion of nutrients were used to assess using sample duplication to control day-to-day variation within animals and errors associated with sampling and laboratory analyses. Two consecutive p... |
The efficient copper-catalyzed cyanoalkylation of amines via C-C bond cleavage has been demonstrated. Distinctive features of this procedure involves mild conditions, broad range of nitrogen nucleophiles, high selectivity, and good functional group tolerance, thus providing a useful approach for the C(sp3)-N bond forma... |
Single vibronic level dispersed fluorescence spectra of jet-cooled HGeBr, DGeBr, HGeI, and DGeI have been obtained by laser excitation of selected bands of the A (1)A(")-X (1)A(') electronic transition. The measured ground state vibrational intervals were assigned and fitted to anharmonicity expressions, which allowed ... |
A principal part of the Comprehensive Research Facility for Fusion Technology (CRAFT) is the toroidal field (TF) coil project, which aims at fabricating a prototype TF coil for China Fusion Engineering Test Reactor (CFETR). The TF coil is composed of 3-D-shaped subwinding packs (sub-WPs) enclosed in a stainless coil ca... |
This work presents a drying theoretical study of banana fruit using diffusion model (Fick ́s law). The governing equation was solved by using the separation of variables technique. For validation, whole banana were peeled manually and dried in an oven at temperatures 40 and 70°C. Predicted results were obtained by fitt... |
In situ growth of CaCO3 on a cleaved (1014) calcite surface from aqueous solution is observed with an atomic force microscope. Growth layers form by the nucleation of steps at spiral sources centered on screw dislocations. The kinetics of simple (isolated) and composite (clustered) spiral sources and the development of... |
Our paper intends to bring some explanations for the high level of spread of the COVID-19 disease, related to the democracy and culture nexus of nations. Our sample consists of worldwide countries affected by the spread of the new coronavirus disease and the paper uses data available to the date of our research for all... |
Four new donor–acceptor type polymeric metal complexes (P1, P2, P3, and P4) with the same Cd(II) complex in side chain and different conjugated backbone structures were synthesized by Yamamoto coupling and applied in dye-sensitized solar cells (DSSCs) as photosensitizers. The photophysical, electrochemical, and thermal... |
Factor VIII-related antigen (FVIIIR:Ag) has been widely used as a marker for endothelial cells. Recent studies have shown that Ulex europaeus agglutinin I lectin (UEAI) also binds specific endothelial cells. To determine the relative utility of the two endothelial cell markers, a group of vascular and nonvascular tumor... |
The aim of this study was to investigate incompetence for oestradiol-induced LH surges in long-term ovariectomized gilts and male pigs. Gilts (250 days old; n = 36), which had been ovariectomized 30 (OVX 30) or 100 days (OVX 100) before the start of treatment, were challenged i.m. with oestradiol benzoate and were eith... |
This work revealed the spherical aromaticity of some inorganic E4 cages and their protonated E4 H+ ions (E=N, P, As, Sb, and Bi). For this purpose, we employed several evaluations like (0D-1D) nucleus independent chemical shift (NICS), multidimensional (2D-3D) off-nucleus isotropic shielding σiso (r), and natural bond ... |
A flowing microwave plasma based methodology for converting electric energy into internal and/or translational modes of stable molecules with the purpose of efficiently driving non-equilibrium chemistry is discussed. The advantage of a flowing plasma reactor is that continuous chemical processes can be driven with the ... |
The Cobalamin activation disorders (CblA‐CblG) are deleterious inborn errors of Vitamin B12 activation, resulting in severe intellectual disability, vision impairment, and seizures. Although cobalamin activation disorders are exceedingly rare, typically occurring 1 in every 200,000 births, Phoenix Children's Hospital h... |
Abstract Despite considerable advances in our understanding of constraint composition, antecedent conditions, outcomes, and negotiation behaviors, few studies have tracked how constraints have changed or remained stable over time. This investigation sought to examine the change and stability in park visitation constrai... |
Spiral waves can be found in various chemical systems, for example in the Belousov–Zhabotinsky-reaction and in the catalysis on platinum surfaces. Such systems can be modelled by reaction-diffusion equations on the plane and have the symmetry of the Euclidean group of the plane. We present a center-manifold reduction (... |
In the neonate the muscles of the tongue, which are exclusively innervated by the XII cranial nerves originating from the brainstem nucleus hypoglossus, must contract rhythmically in coincidence with breathing, suckling and swallowing. These motor commands are generated by hypoglossal motoneurons excited by glutamaterg... |
102 patients with angiographically documented double vessel coronary artery disease were followed for 1-83 months (mean: 42 months). Incidence of sudden death was studied in relation to location and severity of coronary artery lesions, left ventricular wall motion and ventricular arrhythmias found during long-term ECG ... |
Fe-Si layer was prepared on silicon steel substrate from KCl-NaCl-NaF-SiO2 molten salts by pulse current at different time. The quantitative Si concentration depth profile, surface morphology and phase structure of the layer were studied by glow discharge optical emission spectroscopy, atomic force microscopy and X-ray... |
3,3′-Dinitrobisphenol A (dinitro-BPA) is formed in a mixture of bisphenol A (BPA) and nitrite under acidic conditions. It shows genotoxicity in male ICR mice on a micronucleus test, but its estrogenic activity has not been examined in vivo. We examined its estrogenic activity using goldfish (Carassius auratus) by measu... |
MOTIVATION |
The rapid progress in genome sequencing has led to high availability of genomic data. However, due to growing privacy concerns about the participant's sensitive information, accessing results and data of genomic studies is restricted to only trusted individuals. On the other hand, paving the way to biomedical discoveri... |
RESULTS |
In this work, focusing on genomic databases, we show this drawback of DP and we propose techniques to mitigate it. First, using a real-world genomic dataset, we demonstrate the feasibility of an inference attack on differentially private query results by utilizing the correlations between the tuples in the dataset. The... |
AVAILABILITY |
https://github.com/nourmadhoun/Differential-privacy-genomic-inference-attack. |
SUPPLEMENTARY INFORMATION |
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