| { |
| "approved_by_author": "\u231b", |
| "citation": "Lu, Ake T., et al. \"DNA methylation GrimAge strongly predicts lifespan and healthspan.\" Aging (Albany NY) 11 (2019): 303\u2013327.", |
| "citations": 2610, |
| "citations_date": "2026-07-05", |
| "clock_name": "grimage", |
| "data_type": "DNA methylation", |
| "doi": "https://doi.org/10.18632/aging.101684", |
| "journal": "Aging (Albany NY)", |
| "last_author": "Steve Horvath", |
| "model_type": "two-stage elastic net + Cox regression", |
| "n_features": 1032, |
| "notes": "Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.", |
| "platform": [ |
| "Illumina 450K" |
| ], |
| "population": "adults", |
| "postprocess": "cox_to_years", |
| "predicts": [ |
| "mortality risk" |
| ], |
| "reference_values": true, |
| "research_only": true, |
| "species": "Homo sapiens", |
| "tissue": [ |
| "whole blood" |
| ], |
| "training_target": [ |
| "mortality" |
| ], |
| "unit": [ |
| "years" |
| ], |
| "version": "0.5.0", |
| "year": 2019 |
| } |
