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db2aead b3561bc db2aead | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 | {
"approved_by_author": "\u231b",
"citation": "Lu, Ake T., et al. \"DNA methylation GrimAge strongly predicts lifespan and healthspan.\" Aging (Albany NY) 11 (2019): 303\u2013327.",
"citations": 2610,
"citations_date": "2026-07-05",
"clock_name": "grimage",
"data_type": "DNA methylation",
"doi": "https://doi.org/10.18632/aging.101684",
"journal": "Aging (Albany NY)",
"last_author": "Steve Horvath",
"model_type": "two-stage elastic net + Cox regression",
"n_features": 1032,
"notes": "Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.",
"platform": [
"Illumina 450K"
],
"population": "adults",
"postprocess": "cox_to_years",
"predicts": [
"mortality risk"
],
"reference_values": true,
"research_only": true,
"species": "Homo sapiens",
"tissue": [
"whole blood"
],
"training_target": [
"mortality"
],
"unit": [
"years"
],
"version": "0.5.0",
"year": 2019
} |