Sync grimage
Browse files- README.md +38 -0
- config.json +36 -0
- grimage.pt +3 -0
README.md
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---
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license: bsd-3-clause
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library_name: pyaging
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tags:
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- pyaging
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- aging-clock
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- biology
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- dna-methylation
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---
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# grimage
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Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.
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|---|---|
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| **Predicts** | mortality risk |
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| **Species** | Homo sapiens |
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| **Tissue** | whole blood |
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| **Data type** | DNA methylation |
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| **Model type** | two-stage elastic net + Cox regression |
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| **Year** | 2019 |
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## Use with pyaging
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```python
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import pyaging as pya
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pya.pred.predict_age(adata, ["grimage"])
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```
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Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
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## Citation
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Lu, Ake T., et al. "DNA methylation GrimAge strongly predicts lifespan and healthspan." Aging (Albany NY) 11 (2019): 303–327.
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https://doi.org/10.18632/aging.101684
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config.json
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{
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"approved_by_author": "\u231b",
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"citation": "Lu, Ake T., et al. \"DNA methylation GrimAge strongly predicts lifespan and healthspan.\" Aging (Albany NY) 11 (2019): 303\u2013327.",
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"citations": 2610,
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"citations_date": "2026-07-05",
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"clock_name": "grimage",
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"data_type": "DNA methylation",
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"doi": "https://doi.org/10.18632/aging.101684",
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"journal": "Aging (Albany NY)",
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"last_author": "Steve Horvath",
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"model_type": "two-stage elastic net + Cox regression",
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"n_features": 1032,
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"notes": "Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.",
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"platform": [
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"Illumina 450K"
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],
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"population": "adults",
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"postprocess": "cox_to_years",
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"predicts": [
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"mortality risk"
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],
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"reference_values": true,
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"research_only": true,
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"species": "Homo sapiens",
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"tissue": [
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"whole blood"
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],
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"training_target": [
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"mortality"
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],
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"unit": [
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"years"
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],
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"version": "v0.3.0",
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"year": 2019
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}
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grimage.pt
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version https://git-lfs.github.com/spec/v1
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oid sha256:81f69ec6df388ff7586dc7b6de2ba6b438c55a63abe1e419c59ea27e2b3d5a8c
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size 61909
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