metadata
license: mit
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
corticalclock
Cortex-specific DNA-methylation chronological-age estimator trained by elastic net on 1,047 post-mortem cortical samples; its 347-CpG weighted score is back-transformed to years.
| Predicts | chronological age |
| Species | Homo sapiens |
| Tissue | brain cortex |
| Data type | DNA methylation |
| Model type | elastic net regression |
| Year | 2020 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["corticalclock"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Shireby, G. L., et al. "Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex." Brain 143.12 (2020): 3763-3775.