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RESULTS |
In MCF-7 cells, 1,24(OH)2D2 produced synergistic effects with doxonrubicin and cisplatin and additive effects with busulfan, etoposide, tamaxifen, 5-fluorouracil and carboplatin. In LNCaP cells, 1,24(OH)2D2 produced a synergistic effect with carboplatin and additive effects with doxorubicin, busulfan, paclitaxel and et... |
CONCLUSION |
We conclude that 1,24(OH)2D2 may have therapeutic value in the treatment of prostate and breast cancers, alone or in combination with chemotherapeutic agents.Generalization of bipartite graphs |
Abstract Let G = (V, E) be a graph with set of vertices V and set of edges E. An independent set in G is a subset S of V such that no two vertices of S are mutually adjacent. E. Sampathkumar et al. (2003) gave a generalization of independent sets. In this context, we define graph G = V, E) is said to be k-distance bipa... |
In this paper, the advantages of UWB (Ultra-Wide Band) transmission for satellite communications are investigated together with the ones coming from the use of EHF (Extremely High Frequency) where there is the possibility of exploiting a huge spectrum availability. In particular, a comparison among UWB approaches is sh... |
In this paper, we propose a new subspace clustering method that learns a simultaneous low-rank and sparse representation matrix from data. Other than using the nuclear and ℓ1 norms, nonconvex low-rank and sparse approximations are adopted to more accurately measure rank and sparsity. To enhance the robustness, we furth... |
The importance and popularity of software evolution increase as more and more successful software systems become legacy systems. On the one hand, software evolution has become an important characteristic in the software life cycle. On the other hand, software processes play an important role in increasing efficiency an... |
Miniature fission chambers are suited tools for instrumenting experimental reactors, allowing online and in-core neutron measurements of quantities such as fission rates or reactor power. A new set of such detectors was produced by CEA to be used during the next experimental program at the EOLE facility starting in 201... |
Having spent much of the 1970s and 1980s bemoaning the rapid increases in spending on healthcare, the country has spent the last two years talking about various statutory provisions to “rein-in” managed care, the strategy most frequently credited with slowing down spending on health care. While it is difficult not to f... |
For robots to perform advanced manipulation of objects, touch is a critical source of information, and a high-quality tactile sensor is essential. Image-based optical tactile sensors, and its inheritances, which have soft touch interfaces, can provide high-resolution tactile images of the contact geometry, contact pres... |
Significance The acyl chain composition of Chlamydomonas triacylglycerols (TAGs) suggests that they are assembled from prokaryotic precursors, proposed to be synthesized in the chloroplast. However, in most eukaryotes, the endoplasmic reticulum (ER) appears to be the main organelle for storage TAG biosynthesis. Interes... |
The respiratory distress syndrome (RDS) contributes to perinatal morbidity and mortality associated with preterm birth. Surfactant protein B (SP-B) is decreased in RDS. Both maternal antenatal steroid administration and chorioamnionitis reduce the incidence and severity of RDS. An important mediator in chorioamnionitis... |
Let S denote the class of functions of the form that are analytic and univalent in |z| < 1. Given f ∈ S and a, b, c, real numbers other than 0, −1, −2,…, let Ω(a, b, C; f) = F(a, b, C; z)* f(z) where is a hypergeometric Gauss function with (a)0 = 1 and (a)k = a(a + 1) … (a + k − 1) and * denotes the Hadamard product. F... |
Laundry detergent containing anionic surfactants was used to test their effects on plant growth through irrigation water. Lettuce and okra were cultivated in pot experiment and irrigated with distilled water containing domestic detergent at three different concentrations: low concentration (LC) of 0.1 g L-1; normal con... |
BACKGROUND |
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an uncommon progressive or relapsing paralysing disease caused by inflammation of the peripheral nerves. If the hypothesis that it is due to autoimmunity is correct, removal of autoantibodies in the blood by plasma exchange should be beneficial. |
OBJECTIVES |
To evaluate the efficacy of plasma exchange in CIDP. |
SEARCH METHODS |
We searched the Cochrane Neuromuscular Disease Group Specialized Register (14 May 2012), CENTRAL (2012, Issue 4), MEDLINE (January 1966 to May 2012), EMBASE (January 1980 to May 2012), CINAHL Plus (January 1937 to May 2012) and LILACS (January 1982 to May 2012). We also scrutinised the bibliographies of the trials, and... |
SELECTION CRITERIA |
Randomised controlled trials (RCTs) or quasi-RCTs in participants of any age comparing plasma exchange with sham treatment or no treatment. |
DATA COLLECTION AND ANALYSIS |
Two authors selected the trials, extracted the data and assessed risk of bias independently. Where possible data were combined according to the methods of the Cochrane Neuromuscular Disease Review Group. |
MAIN RESULTS |
PRIMARY OUTCOME MEASURE |
one cross-over trial including 18 participants showed two (95% confidence interval (CI) 0.8 to 3.0) points more improvement after four weeks on an 11-point disability scale with plasma exchange (10 exchanges over four weeks) than with sham exchange. Rapid deterioration after plasma exchange occurred in eight of 12 who ... |
SECONDARY OUTCOME MEASURES |
when the results of this trial and another with 29 participants treated in a parallel group design trial were combined, there were 31 points (95% CI 16 to 45, maximum score 280) more improvement in an impairment scale after plasma exchange (six exchanges over three weeks) than after sham exchange. There were significan... |
AUTHORS' CONCLUSIONS |
Moderate to high quality evidence from two small trials showed that plasma exchange provides significant short-term improvement in disability, clinical impairment and motor nerve conduction velocity in CIDP but rapid deterioration may occur afterwards. Adverse events related to difficulty with venous access, use of cit... |
Peritoneal dialysis is a new renal replacement therapy recently introduced in Morocco since 2006. Continuous ambulatory peritoneal dialysis has proven to be as effective as hemodialysis. However, it is associated with several complications. The aim of this study was to evaluate the outcome of complications in patients ... |
AIM |
To study an impact of cytoflavin on the functional state of erythrocytes in patients with Charcot - Marie - Toota disease (CMTD). |
MATERIAL AND METHODS |
Thirty patients with CMTD were examined. The main group (n=17) received cytoflavin along with basic therapy (intravenously dropwise 10 ml per 200 ml of 5% glucose solution for 10 days). The comparison group (n=13) received only basic therapy. Functional parameters of erythrocytes, including electrophoretic mobility of ... |
RESULTS AND CONCLUSION |
There was a decrease in EFME and concentrations of ATP, 2.3 DFG and an increase in MDA concentration in the main group compared to the control group. After treatment with cytoflavin, there was an increase in the content of ATP, 2.3 DFG and EFME and a decrease in the concentration of MDA. The similar but less pronounced... |
Evaluation plays a central role in the use of evidence. Evidence from evaluations about which programmes work, for whom, why and in what context is important for evidence-informed policy or practice. The use of evidence in international development has developed through four waves (White 2018b). The first wave was a fo... |
The monograph summarizes the legislative and regulatory framework, as well as shows the theory and practice of energy saving and energy efficiency development in Russia and in the world with the actualization of the use of a breakthrough domestic high-energy-efficient technology based on molecular heat generators Terma... |
The free carrier Faraday effect is considered in both the Drude model and the Appel-Overhauser model for inversion layer electrons at the SiC>2-Si interface. An exact algebraic relation between the photon, cyclotron, collision and plasma frequencies is obtained which must be satisfied in order to achieve null rotation ... |
High-turbulence flow conditions in gas turbine combustors create a rough environment for film cooling flows. Fundamental knowledge of the interaction between main flow fluctuations and cooling jet is essential to develop more efficient cooling geometries. To gain detailed insight into the turbulent flow structures, hig... |
The daily activity cycles of marine predators may be dictated in large part by the timing of prey availability. For example, recent studies have observed diel periodicity in baleen whale vocalization rates that are thought to be governed by the diel vertical migration of their zooplanktonic prey. We addressed this hypo... |
Background Infectious endocardits (IE) is a rare condition associated with high morbidity and mortality. IE develops as a result of a complex interaction between the vascular endothelium, haemostatic mechanisms, the immune system and exposure to the causative microorganism. Historically cardiologists have utilised prop... |
Members of the Semaphorin family of glycoproteins play an important role in axonal pathfinding by functioning as inhibitory guidance cues. Here we provide evidence that a transmembrane form of Semaphorin (Semaphorin I), which is expressed by bands of epithelial cells in the developing grasshopper limb bud, functions as... |
This article presents a microwave imaging (MWI) algorithm that can incorporate prior structural information, also known as spatial priors (SP), about the object being imaged to enhance the achievable image quantitative accuracy. This algorithm: 1) is fully automated and 2) can work with both complete and partially avai... |
In the previous century, ancient migration was explained on the basis of the occurrence and quantities of imported archaeological artefacts, and with interpretations made in alignment with the ancient written sources. This was so too with the Greek migration into Southern Italy, often referred to as ‘Greek colonization... |
The international Passive House Standard delivers high thermal comfort based on the principles of excellent building fabric and balanced mechanical heat recovery ventilation. Considering that the typical person in industrial countries (such as the UK) spends ∼90% of their time indoors, there are surprisingly few academ... |
In this paper, we characterize twin apartments in twin buildings by means of the opposition relation on chambers. We also characterize adjacency of chambers in twin buildings by means of opposition of chambers. As an application, we study maps which satisfy certain conditions related to opposition of chambers, e.g. map... |
40 IE E E S P E C T R U M • M ay 2 00 2 T he battle between codemakers and code-breakers is centuries old, but at the start of the 21st century, could it finally be drawing to a close? Physicists are putting the finishing touches on a method of encrypting messages that is more secure than anything that has gone before.... |
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