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We read with interest the publication by Drs. Pham and Mullins examining the safety of non-steroidal anti-inflammatory drug (NSAID) administration to victims of copperhead snakebite [1]. As the authors correctly note, current recommendations to avoid NSAID administration to pit viper envenomation patients are based upo... |
Fitting multilevel models to diary data allows the analysis of development trends, group differences, and breakpoints in time trends. The aim of this study is the application of multilevel modelling to determine time trends in the diary data of a group of obese patients with and without binge eating disorder (BED). Thr... |
Shortwave radiative forcing of climate by anthropogenic sulfate aerosols is estimated to be equal in magnitude but opposite in sign to that of greenhouse warming, with a global annual average value of approximately -1 W m{sup -2} uncertain to at least a factor of two. Estimates of the 2 contributions to this forcing by... |
A cell adhesive peptide, Arg-Gly-Asp (RGD), was immobilized onto the surface of electrospun poly(D,L-lactic-co-glycolic acid) PLGA nanofiber mesh in an attempt to mimic an extracellular matrix structure. A blend mixture of PLGA and PLGA-b-PEG-NH(2) di-block copolymer dissolved in a 1:1 volume mixture of dimethylformami... |
Virtual reality is a new technology that simulates a three-dimensional virtual world on a computer and enables the generation of visual, audio, and haptic feedback for the full immersion of users. Users can interact with and observe objects in three-dimensional visual space without limitation. At present, virtual reali... |
External latchup phenomena in 65nm CMOS technology under transient events are studied. The effect of different design schemes such as injector to detector spacing, detector orientation, guardring protection strategy and also process factors such as wafer resistivity are investigated. The distance of latchup structures ... |
UNLABELLED |
There is little research in Southeast Asia focusing on patients' experiences of seeking psychological treatment for chronic pain. |
OBJECTIVE |
This study aims to understand the experiences of patients seeking psychological treatment for chronic pain in this region. |
SETTING |
Outpatient pain clinic at a tertiary hospital in Singapore. |
SUBJECTS |
People with experiences of attending psychological treatment for chronic pain, including some who were not receiving this type of treatment. |
STUDY DESIGN AND METHODS |
Fifteen inductive semi-structured interviews were conducted to explore patients' experiences regarding psychological treatment for their chronic pain. Thematic analysis was then applied. |
RESULTS |
Three main themes were identified: "Expectations and Realities of Health Professionals," "Patients' Attitudes and Beliefs," and "Practical and Social Factors." From the patients' perspectives, an empathetic health professional who was willing to listen contributed to a positive treatment seeking experience. Patients fe... |
CONCLUSION |
Education for both patients and health professionals unfamiliar with psychological treatments for pain may improve access to these treatments.Tracheal compression by the innominate artery in infancy and childhood. |
The authors evaluated the normal radiographic anatomy of the innominate (brachiocephalic) artery in children. Review of 1,000 randomly selected lateral chest radiographs demonstrated anterior tracheal indentation in 30% of the children under the age of 2 years. In addition, 172 angiograms in children with congenital he... |
Retroviral integration requires cis-acting sequences at the termini of linear double-stranded viral DNA and a product of the retroviral pol gene, the integrase protein (IN). IN is required and sufficient for generation of recessed 3' termini of the viral DNA (the first step in proviral integration) and for integration ... |
In this paper, we propose a method to embed side in- formation into MP3 bitstream using a data hiding technique. Usually, side information is transmitted in ancillary data field of an MP3 packet, which is independent of audio bitstream. When a certain amount of side information is packed into an ancillary data field, b... |
Aseptic loosening resulting from periprosthetic osteolysis continues to be an important cause of hip implant failure. Wear particles from the bearing surfaces play a major role in initiating periprosthetic osteolysis, which is also potentiated by mechanical factors such as increased synovial fluid pressure. The precise... |
Accurate imaging of glutathione (GSH) in vivo is able to provide real-time visualization of physiological and pathological conditions. Herein, we successfully synthesize bimetallic oxide MnMoOX nanorods as an intelligent nanoprobe for in vivo GSH detection via photoacoustic (PA) imaging. The obtained MnMoOX nanoprobe w... |
One of the goals of the ESA project GlobSnow is to develop a global product and a near-real-time service for Snow Extent (SE) and carry out snow mapping of the whole seasonally snow-covered Earth for the years 1995–2010 based on the optical sensors ERS-2 ATSR-2 and Envisat AATSR data. A laboratory processing chain has ... |
Idiopathic epilepsies are genetically determined diseases of the central nervous system characterized by typical epileptic seizures and EEG abnormalities but not associated with structural brain lesions. In recent years, an increasing number of mutations associated with idiopathic epilepsy syndromes were identified in ... |
In this study, behaviour of reinforced concrete columns strengthened using fiber reinforced polymer (FRP; glass fiber and carbon fiber) after fire exposure are discussed. After being exposed to fire as high as 720 o C for 180 minutes, the specimens showed concrete and reinforcement strength degradation, even though th... |
AIM |
To determine the stimulation site of both facial and hypoglossal nerves after transcranial magnetic stimulation. |
METHODS |
After surgical exposure of the brainstem in 22 patients with intrinsic pontine (n=9) or medullary (n=13) tumors, the facial colliculus and the hypoglossal triangle were electrically stimulated. The EMG responses were recorded with flexible wire electrodes from the orbicularis oculi/orbicularis oris muscles, and geniogl... |
RESULTS |
The EMG mean latencies of the unaffected facial nerve were 5.2+/-0.6 ms for the orbicularis oculi, and 5.2+/-0.5 ms for the orbicularis oris muscle. After the stimulation of 18 possibly affected facial nerves, the EMG mean latencies were 5.3+/-0.3 ms for the orbicularis oculi (p=0.539, unpaired Student's t-test), and 5... |
CONCLUSION |
Shorter EMG mean latencies of unaffected facial nerves obtained after direct stimulation of the facial colliculi confirm that magnetic stimulation is most likely to occur closer to the nerve's exit from the brainstem than to its entrance into the internal auditory meatus. The hypoglossal nerve seems to have the site of... |
The present experiment was designed to evaluate the development of tolerance to alcohol and cross‐tolerance to nicotine in adolescent mice. C57BL/6J mice (30–40 days old) were injected IP with alcohol (2.5 g/kg) for 4 consecutive days. A control group received four saline injections. On the test day, all subjects recei... |
418 The Journal of Clinical Phmarmnacology T HE various mechanisms and pharmacological implications of drugs showing dose-dependent bioavailability properties have been thoroughly reviewed by Rowland.’ It has been shown that the fraction of dose absorbed may decrease with increasing dose for (a) poorly water-soluble dr... |
Highly active antiretroviral therapy (HAART) significantly reduced the toxoplasmic encephalitis (TE) incidence in acquired immunodeficiency syndrome (AIDS) patients. The TE incidence and mortality were evaluated in an AIDS cohort followed in Puerto Rico before, during, and after HAART implementation in the Island. Of t... |
The extent to which circulating leukocytes reflect functional capacity at the site of infection is unclear despite a century of debate. We conducted experiments designed to clarify those relationships as well as the relationship of pleural and peritoneal responses to infection. Empyema was established in inbred CBA/J m... |
Regulating oral rinses has been and still is a topic of debate and confusion. Oral rinses are products that are mainly used for cleaning, perfuming and changing the appearance of the teeth, which in turn improves the individual’s external appearance. Adding medicinal ingredients to these rinses, it can then be used for... |
Color transformations Induction Rook polynomials Rotating decimals Regular closed linkages Factorial polynomials Integer geometry Unit fractions Chromatic polynomials Twenty-five point affine geometry Square-sum partitions Slides, rolls, and rolides Pythagorean triples Cevians Insane tic-tac-toe Three addition problems... |
ABSTRACT Alphavirus glycoproteins E2 and E1 form a heterodimer that is required for virus assembly. We have studied adaptive mutations in E2 of Sindbis virus (SIN) and E1 of Ross River virus (RR) that allow these two glycoproteins to interact more efficiently in a chimeric virus that has SIN E2 but RR E1. These mutatio... |
With aging, there is an increasing risk for women to develop perimenopause syndrome, which is harmful to women's physical and mental health. The present study investigated the health benefits of bilberry anthocyanin (BA) on aging perimenopausal Sprague-Dawley rats. Rats that entered into perimenopause through natural a... |
This study investigated the effects of acute and chronic cystitis on sensitivity to peripheral mechanical stimuli applied to hind paws of rats and changes in content of NGF, BDNF, tyrosine kinase A (trkA), and tyrosine kinase B (trkB) the high affinity receptor for NGF and BDNF, respectively within the bladder, dorsal ... |
The question of whether there is a logic that captures polynomial time is one of the main open problems in descriptive complexity theory and database theory. In 2010 Grohe showed that fixed point logic with counting captures polynomial time on all classes of graphs with excluded minors. We now consider classes of graph... |
Surfactants are frequently used in the preparation of background electrolytes (BGEs) in capillary zone elcetrophoresis (CZE) in order to affect and to optimize both the electroosmotic flow (EOF) and the separation process. Their effects are, however, always multiple, the resulting situation may be very complex and the ... |
Image classification and object detection using deep learning have evolved with continuous research. In particular, the development of big data and the improvement of computer hardware performance have contributed extremely to the development of deep learning. Deep learning technologies like Convolutional Neural Networ... |
Objective:Mounting evidence suggests a role for glucose variability in predicting intensive care unit (ICU) mortality. We investigated the association between glucose variability and intensive care unit and in-hospital deaths across several ranges of mean glucose. Design:Retrospective cohort study. Setting:An 18-bed me... |
The requirement for rational drug design in the search for new agents that are active against parasitic protozoa prompted our in vitro studies with a group of 9-anilinoacridines. In vitro growth assays with Trypanosoma lewisi identified a series of C-1' alkylaminoacridines which possess previously unreported potent gro... |
Robots operating in public spaces, such as autonomous vehicles, will necessarily collect images and other data concerning the people and vehicles in their vicinity, raising privacy concerns. Common conceptions of privacy in robotics do not include the challenges of many-to-many surveillance where fleets of many individ... |
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