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Answer the following medical question with the correct option:
Mechanism of action of azoles is A) By altering membrane permeability B) By blocking nucleic acid synthesis C) By disrupting microtubules function D) By inhibiting cell wall synthesis
A) By altering membrane permeability
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Radioisotopes are used in the following technique except – A) Mass spectroscopy B) RIA C) ELISA D) Sequencing of nucleic acid
C) ELISA
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Erlenmeyer flask deformity is classical X-ray finding in A) Pompe's disease B) Gauchers disease C) Sandhoff's disease D) Von Gierke disease
B) Gauchers disease
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Morphine should not be used in: A) Ischaemic pain B) Biliary colic C) Cancer pain D) Post-operative pain
B) Biliary colic
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Permanent mandibular first molar is a common site for all the lesions EXCEPT A) Pulp polyp B) Condensing osteitis C) Lateral periodontal cyst D) Benign cementohlastoma
C) Lateral periodontal cyst
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Interval between primary and secondary cases ? A) Latent period B) Communicable period C) Serial interval D) Generation time
C) Serial interval
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Which of the following produce gastrin? A) Mucous neck cells B) Parietal cells C) Chief cells D) Endocrine cells
D) Endocrine cells
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Which of the following statement is true about vasa pre A) Seen in 1:1500 pregnancies B) Moality rate is 20% if left undiagnosed C) Associated with low-lying placenta D) Cesarean section is indicated
D) Cesarean section is indicated
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Quinidine belongs to class antiarrhythmic drug is A) Class I B) Class II C) Class III D) Class IV
A) Class I
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Which of the following jaw cyst is pre-malignant? A) Nasopalatine cyst B) Radicular cyst C) Odontogenic keratocyst D) Dentigerous cyst
C) Odontogenic keratocyst
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According to the European Laryngological Society, Subligamental cordectomy is classified as - A) Type I B) Type II C) Type III D) Type IV
B) Type II
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P.Q.L.I is A) IMR, Life Expectancy at 1year of age, literacy B) MMR, Life expectancy, literacy C) MMR, IMR, Life expectancy D) IMR, Life expectancy at 1 year of age, SE status
A) IMR, Life Expectancy at 1year of age, literacy
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Which amino acid does not take part in transamination A) Proline B) Alanine C) Tryptophan D) Histidine
A) Proline
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Day care surgery uses A) Sodium thiopentone B) Propofol C) Methoxitone D) Ether
B) Propofol
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A patient suffers from contraction of maxillary arch, labioversion of maxillary incisors, with deep overbite and overjet. These are features of: A) Class I malocclusion B) Class II div 2 malocclusion C) Class II div 1 malocclusion D) Class III malocclusion
C) Class II div 1 malocclusion
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Commonly undergoing malignant transformation is/are :a) FAPb) Crohn' s diseasec) Ulcerative colitisd) Enteric colitise) Juvenile polyposis A) a B) bc C) ac D) b
C) ac
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Gastric carcinoma is associated with all EXCEPT ? A) Inactivation of p53 B) Over expression of C-erb C) Over expression of C-met D) Activation of RAS
D) Activation of RAS
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Multiple regression analysis is applied to A) Compare medians of two independent samples B) Compare medians of several independent samples C) Tests association between two categorical variables D) Tests relation between dependent variable and several independent variables
D) Tests relation between dependent variable and several independent variables
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Most common cause of sub-dural haematoma - A) Middle meningeal artery tear B) Rupture of superior cerebral vein C) Internal carotid artery tear D) None of the above
B) Rupture of superior cerebral vein
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A child is presenting with vomiting and abdominal pain after 5 hours of eating some food. The most likely causative orgonism - A) Bacillus cereus B) Cl. perfringens C) Cl. botulinum D) V. cholerae
A) Bacillus cereus
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In an old patient, the best indicator of probability of developing cardiovascular disease can be calculated by:- A) LDL/HDL ratio B) Triglycerides C) Total cholesterol D) Serum LDL
A) LDL/HDL ratio
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Alpha 2 agonist cause all of the following Except A) Analgesia B) Hyperalgesia C) Sedation D) Anxiolysis
B) Hyperalgesia
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A 30 years old male patient presents with weakness of right upper and both lower limbs since 4 months. He developed digital infarcts involving 2nd and 3rd fingers on right side and 5th finger on left side. On examination, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. I...
A) Polyaeritis nodosa
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What is the most common site of osteosarcoma: A) Lower end of femur B) Upper end of humerus C) Lower end of tibia D) Upper end of femur
A) Lower end of femur
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All are fibrinolytic, EXCEPT : A) Streptokinase B) Urokinase C) Alteplase D) Epsilon amino caproic acid
D) Epsilon amino caproic acid
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The term "dementia" describes all of the following clinical states, EXCEPT: A) Gradual decline in ceain mental operations such as orientation, cognition, and memory B) Presence of a specific language disorder such as aphasia, alexia, or agraphia C) Onset of behavioral changes including apathy, eccentricity, and distra...
B) Presence of a specific language disorder such as aphasia, alexia, or agraphia
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A drug used in estrogen-dependent breast cancer A) Clomiphene citrate B) Tamoxifen C) Estrogen D) Adriamycin
B) Tamoxifen
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The perinatal HIV transmission can be reduced by the following measures except - A) Intrapaum antiretroviral therapy B) Delivery by elective cesarean section C) Antiretroviral therapy to the neonate D) Breastfeeding
D) Breastfeeding
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Wof glucocoicoid has significant (max) mineralocoicoid activity A) Dexamethasone B) Triamcinolone C) Hydrocoisone D) Betamethasone
C) Hydrocoisone
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Inhibition of anaerobic glycolysis by increase supply of O2 is called: A) Carbtree effect B) Pasteur effect C) Lewis effect D) None
B) Pasteur effect
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Carcinoma common in dye industry workers is A) TCC of bladder B) SCC of bladder C) Adenocarcinoma of bladder D) All of the above
A) TCC of bladder
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Baby born at 30 weeks for 18-year-old prior gravida of weight 2 kg which died after 48 hours. Apgar scores were 5 and 8 at 1 and 5 minutes. On autopsy bilateral enlarged kidney with multiple radially arranged cysts. Which of the following finding is expected to be associated with? A) Imperforate anus B) Hepatic cyst a...
B) Hepatic cyst and fibrosis
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True about CP angle tumour: A) Absent corneal reflex B) Superior oblique palsy C) Pupillary dilatation D) Medial rectus palsy
A) Absent corneal reflex
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A 35-year old male with a history of severe bronchial asthma for several months now complains of weight gain and the development of purple stretch marks. Physical examination shod BP - 149/95 mmHg. supraclavicular fullness. The skin was thinned out with areas of bruising. Neurological examination revealed deceased stre...
C) Hypokalemia
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Antidote for organophosphorous poisoning is:(1995) A) Atropine B) Neostigmine C) Susccinylcholine D) D tubocurarine
A) Atropine
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Which of the these can cause both rhabdomyolysis and myoglobinuria -a) Hyperpyrexiab) Viper snake venomc) Multiple hornet stings d) Anemia A) ac B) bc C) ad D) b
A) ac
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A short stature child's growth variation is normal but bone development is not according to chronological age. What is your diagnosis? A) Genetic short stature B) Dwarfism C) Constitutional delay D) Growth hormone deficiency
C) Constitutional delay
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All are symptoms of deep vein thrombosis except: A) High grade fever B) Local rise of temperature C) Pain D) Swelling
A) High grade fever
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Chediak higashi syndrome, defect is ? A) Fusion of lysosome B) T-cells C) B-cells D) Complement
A) Fusion of lysosome
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Time interval betwen inoculation of infection to maximum infectivity is ? A) Lead time B) Median incubation period C) Generation time D) Serial inverval
C) Generation time
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Surgical treatment of Ulcerative colitisa) Done in late cases onlyb) Done in cases where medical treatment fails c) Pouch surgery doned) Restorative proctocolectomy done in emergency cases A) bc B) c C) ac D) ad
A) bc
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A 45-year old female had sought medical attention for her recent increase in weight and proximal limb weakness. She was diagnosed with rheumatoid ahritis. 1 week ago has been staed on prednisolone tablets. Physical examamination revealed truncal obesity; BP - 145/90 mm Hg and PR- -90/ mill. High levies of coisol were f...
B) MRI of the brain
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Which muscle causes retraction of scapula ? A) Serratus anterior B) Levator scapulae C) Rhomboideus major D) Supraspinatus
C) Rhomboideus major
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Gas gangrene is/are caused by- A) C. novyi B) C. septicum C) C. histolyticum D) All
D) All
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Diabetic patient with liver cirrhosis and hyperpigmentation, diagnosis is ? A) Wilson's disease B) Hemochromatosis C) Primary sclerosing cholangitis D) Hepatitis B
B) Hemochromatosis
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Most sensitive test for microfilariae? A) DEC challenge test B) Immunofluorescence test C) Thick films D) Membrane filter concentration technique
D) Membrane filter concentration technique
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Features of Gartner's cyst are all except A) Well defined margins B) Cough impulse present C) Not reducible D) Rugosities of vaginal mucosa lost
B) Cough impulse present
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Striated veebrae is seen in WHICH OF THE FOLOWING CONDITION ? A) TB spine B) Hemangioma C) Chordoma D) Metastasis
B) Hemangioma
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Prevalence of all clinical cases of polio can be estimated by multiplying the no. of residual paralytic cases by - A) 1.33 B) 1.25 C) 3 D) 1.99
A) 1.33
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In sjogren syndrome salivary flow rate of each parotid becomes: A) 5ml/min. B) 2ml/min. C) 1ml/min. D) 0.5ml/min.
D) 0.5ml/min.
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Louse borne relapsing fever - A) B duttoni B) B recurrentis C) B parkeri D) B burgdorferi
B) B recurrentis
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Most common type of pneumoconiosis, associated with TB is? A) Silicosis B) Bysinosis C) Asbestosis D) Baggassosis
A) Silicosis
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Most common type of carcinoma of lung is A) Small cell carcinoma B) Adenocarcinoma C) Squamous cell carcinoma D) Large cell carcinoma
B) Adenocarcinoma
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Sensory supply of palatine tonsil is by which cranial nerve? A) IXth B) Xth C) XIth D) VIIth
A) IXth
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Alzheimer's Disease is associated with : A) Delerium B) Delusion C) Dementia D) Depression
C) Dementia
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An amino acid that does not form an a-helix is: A) Asparagine B) Tyrosine C) Tryptophan D) Proline
D) Proline
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All of the following are devoid of blood brain barrier except A) Organum Vasculosum B) Median Eminence C) Adenohypophysis D) Pineal gland
C) Adenohypophysis
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Which one of the following statements best describes immunoglobulin structure? A) The amino acid sequence variation of the heavy chains is different than that observed in light chains B) In humans, there are approximately twice as many Ig molecules with k and l chains C) In the three-dimensional structure of Ig, there...
B) In humans, there are approximately twice as many Ig molecules with k and l chains
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The first centres of ossification appears during which month of pregnancy A) At the end of 2nd month of pregnancy B) At the beginning of 3rd month of pregnancy C) At the end of 3rd month of pregnancy D) At the end of 4th month of pregnancy
A) At the end of 2nd month of pregnancy
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Woody feeling of the external nose (Hebra nose) is observed in A) Rhinophyma B) Rhinoscleroma C) Rhinosporidiosis D) Rhinitis sicca
B) Rhinoscleroma
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Alternative episodes of hypomania and subsyndromic depression is called as A) Type I Bipolar disorder B) Type II Bipolar disorder C) Type III Bipolar disorder D) Type IV Bipolar disorder
C) Type III Bipolar disorder
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low tracheostomy is incision below A) 2nd Tracheal ring B) 3rd Tracheal ring C) 4th Tracheal ring D) 1st Tracheal ring
C) 4th Tracheal ring
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Virilising tumours of the ovary are : A) Arrhenoblastoma B) Adrenal tumours of the ovary C) Leydig cell tumour and Gynandroblastoma D) All of the above
D) All of the above
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The oculomotor nerve passes between which pair artery? A) A Superior cerebellar artery and posterior cerebral artery B) Posterior inferior cerebellar artery and anterior-cerebellar artery C) Posterior cerebellar artery and middle cerebral Artery D) Posterior cerebral communicating artery
A) A Superior cerebellar artery and posterior cerebral artery
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All are feature of Wernicke's encephalopathy,Except: A) Cogwheel rigidity B) Alteration in mental function C) 6th nerve palsy D) Ataxia
A) Cogwheel rigidity
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It is true regarding Endemic typhus that - A) Man is the only reservoir of infection B) Flea is a vector of the disease C) The rash developing into eschar is a characteristic presentation D) Culture of the etiological agent in tissue culture is a diagnostic modality
B) Flea is a vector of the disease
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Floor of Petit triangle is formed by? A) Sacrospinalis B) Internal oblique C) Rectus abdominis D) Fascia Transversalis
B) Internal oblique
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Which is not a pa of Kaageners syndrome:March 2007 A) Situs inversus B) Chronic sinusitis C) Bronchiectasis D) Cardiomegaly
D) Cardiomegaly
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Cavitatory lesions in lung are seen in A) Primary pulmonary Tuberculosis B) Staphylococcal pneumonia C) Pneumoconiosis D) Interstitial Lung disease
B) Staphylococcal pneumonia
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Chronic villous sampling is done at : A) 4-6 weeks B) 7-8 weeks C) 9-11 weeks D) 12-13 weeks
C) 9-11 weeks
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All of the following open into right atrium except A) Anterior cardiac vein B) Venae cordis minimi C) Coronary sinus D) Middle cardiac vein
D) Middle cardiac vein
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All of the following are derivatives of connective tissue except A) Endothelial cells B) Clara cells C) Fibroblast D) Mast cells
B) Clara cells
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Apolipoprotein activating L- CAT (LQ) A) B - 48 B) A - I C) A- II D) B-100
B) A - I
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Osteoblastic secondaries occurs with A) Carcinoma prostate B) Carcinoma rectum C) Carcinoma endometrium D) Wilm's tumour
A) Carcinoma prostate
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Emporiatrics deals with the health of the - A) Farmers B) Travellers C) Industrial workers D) Mine workers
B) Travellers
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The basic pathology of Barrett's esophagus is: A) Metaplasia of columnar cells to squamous cells B) Metaplasia of squamous cells to columnar cells C) Dysplasia of Epithelium D) Low pressure in Lower sphincter
B) Metaplasia of squamous cells to columnar cells
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Lacunar infarcts may manifest all of the following except: A) Pure sensory weakness B) Pure motor weakness C) Ataxia paresis D) Quadriparesis
D) Quadriparesis
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All are seen in malignant hypertension except - A) Fibrinoid necrosis B) Hyaline arteriolosclerosis C) Necrotizing glomerulonephritis D) Hyperplastic arteriolosclerosis
B) Hyaline arteriolosclerosis
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In an accidental needle stick, an unknown quantity of blood from an AIDS patient is injected into a nurse. The most recent laboratory report on the AIDS patient shows a CD4 count of 20/µl and a viral RNA load of greater than 107copies/ml. The most appropriate course of action regarding the treatment of the nurse is to ...
D) Administer zidovudine with lamivudine for 4 weeks
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Muddy brown casts are seen in A) Chronic renal failure B) Acute tubular necrosis C) Nephrotic syndrome D) Nephritic syndrome
B) Acute tubular necrosis
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The class of low molecular weight calcium binding proteins seen predominantly in developing enamel are: A) Enamelin B) Amelogenin C) Tuftelin D) Ameloplakin
B) Amelogenin
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Characteristic feature of Otosclerosis are all except- A) Conductive deafness B) Positive rinne's test C) Paracusis willisii D) Mobile ear drum
B) Positive rinne's test
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All of the following drugs are Antiandorgens EXCEPT A) Cemitidine B) Cyproterone C) Spironolactone D) Cyproheptadine
D) Cyproheptadine
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Blastocyst implantation close to internal os causes A) Placenta pre B) Placenta percreta C) Placenta increta D) Abruptio Placenta
A) Placenta pre
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A 13-year-old female presents with lethargy, fever, severe headache, and a stiff neck. On examination, a unilateral fixed, dilated pupil and papilledema is noted. Each of the following would be appropriate in initial management, EXCEPT: A) Intubation and hyperventilation B) Mannitol administered intravenously C) Compu...
D) Lumbar puncture
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Anemia of chronic disease is characterized by A) Increased sideroblasts B) Increased TIBC C) Increased bone marrow iron D) Increased protoporphyrin
C) Increased bone marrow iron
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True statement regarding pathology of pneumocystis jiroveci pneumonia: A) Alveoli is filled with foamy exudates B) Interstitial pneumonitis with foamy vacuoles C) Necrotising hemorrhage D) Pleural effusion
A) Alveoli is filled with foamy exudates
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Fermentation of pulses increases all the following except A) Thiamine B) Riboflavin C) Niacin D) Ascorbic acid
D) Ascorbic acid
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Diuretic that is useful in mild to moderate hypertension is: A) Loop diuretics B) Thiazides C) Osmotic diuretics D) Potassium sparing diuretics
B) Thiazides
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All of the following Mesenteries are present in an Adult, except: A) Mesentery of transverse colon B) Mesenery of appendix C) Mesentry of sigmoid colon D) Mesentery of Rectum
D) Mesentery of Rectum
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Which of the following cast is normal in urine A) Granular B) Waxy C) Epithelial D) Hyaline
D) Hyaline
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Treatment of choice for Eale's disease ? A) Antibiotics B) Coicosteroids C) Antihistaminics D) Surgery
A) Antibiotics
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Stages of anaesthesia were established by – A) Ether B) N2O C) Halothane D) Chloroform
A) Ether
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In a case of retrocecal appendicitis which movement aggravates pain A) Flexion B) Extension C) Medial rotation D) Lateral rotation
B) Extension
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A 56-year-old man presented with bony pain. X-ray of skull showing which lesions in brain: A) Paget's disease B) Multiple myeloma C) Osteosarcoma D) Osteomyelitis
A) Paget's disease
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False denticles are all except A) Do not exhibit dentinal tubules B) Localized masses of calcified tissue resembling dentin C) Appear as lamellae deposited around a central nidus D) Larger than true denicles
B) Localized masses of calcified tissue resembling dentin
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Definitive diagnosis of sporotrichosis generally depends on: A) Serology B) Culture C) Biopsy D) KOH preparation from the lesion
B) Culture
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FEV1/FEVC ratio is decreased in all,except : A) Bronchiectasis B) Emphysema C) Chronic bronchitis D) Tuberculosis
D) Tuberculosis
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Stability of alveoloi is maintained by: A) Compliance of the lungs B) Residual air in alveoli C) Negative intrapleural pressure D) Reduce surface tension by surfactant
D) Reduce surface tension by surfactant
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Gradenigo's syndrome involves the following cranial nerves: A) IV, VII B) V, VI C) VI, DC D) VII, VIII
B) V, VI