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metadata
license: mit
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

weidner

Three-site whole-blood epigenetic-age estimator. The sites were selected from Illumina 27K blood profiles, and the final multivariate linear equation was fitted on targeted bisulfite-pyrosequencing beta values from 82 blood samples and validated in 69 independent samples.

Predicts biological age
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type linear regression
Year 2014

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["weidner"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Weidner, C. I., Lin, Q., Koch, C. M., et al. (2014). Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biology, 15, R24.

https://doi.org/10.1186/gb-2014-15-2-r24