| --- |
| license: mit |
| library_name: pyaging |
| tags: |
| - pyaging |
| - aging-clock |
| - biology |
| - dna-methylation |
| --- |
| |
| # stemtocvitro |
|
|
| In-vitro precursor of stemTOC based on the 95th percentile across 629 population-doubling-associated CpGs. |
|
|
| | | | |
| |---|---| |
| | **Predicts** | mitotic age | |
| | **Species** | Homo sapiens | |
| | **Tissue** | multi-tissue, cultured human cells | |
| | **Data type** | DNA methylation | |
| | **Model type** | 95th-percentile methylation aggregation | |
| | **Year** | 2024 | |
|
|
| ## Use with pyaging |
|
|
| ```python |
| import pyaging as pya |
| |
| pya.pred.predict_age(adata, ["stemtocvitro"]) |
| ``` |
|
|
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). |
|
|
| ## Citation |
|
|
| Zhu, Tianlei, et al. "An improved epigenetic counter to track mitotic age in cells." Nature Communications 15 (2024): 4211. |
|
|
| https://doi.org/10.1038/s41467-024-48649-8 |
|
|
