hypoclock / config.json
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{
"approved_by_author": "\u231b",
"citation": "Teschendorff, Andrew E. \"A comparison of epigenetic mitotic-like clocks for cancer risk prediction.\" Genome Medicine 12 (2020): 56.",
"citations": 452,
"citations_date": "2026-07-05",
"clock_name": "hypoclock",
"data_type": "DNA methylation",
"doi": "https://doi.org/10.1186/s13073-020-00752-3",
"journal": "Genome Medicine",
"last_author": "Andrew E. Teschendorff",
"model_type": "mean aggregation",
"n_features": 678,
"notes": "Pyaging returns an inverted HypoClock burden score, 1 minus the mean beta value across 678 solo-WCGW CpGs; higher values therefore indicate deeper PMD hypomethylation. The assigned 2018 paper is the biological precursor, while the named 678-site implementation is from 2020.",
"platform": [
"Illumina 450K"
],
"population": "human, age unspecified",
"postprocess": "one_minus",
"predicts": [
"mitotic age"
],
"preprocess": "mean",
"reference_values": true,
"research_only": null,
"species": "Homo sapiens",
"tissue": [
"multi-tissue"
],
"training_target": [
"not applicable"
],
"unit": [
"beta value"
],
"version": "0.5.0",
"year": 2020
}