| { |
| "approved_by_author": "\u231b", |
| "citation": "Teschendorff, Andrew E. \"A comparison of epigenetic mitotic-like clocks for cancer risk prediction.\" Genome Medicine 12 (2020): 56.", |
| "citations": 452, |
| "citations_date": "2026-07-05", |
| "clock_name": "hypoclock", |
| "data_type": "DNA methylation", |
| "doi": "https://doi.org/10.1186/s13073-020-00752-3", |
| "journal": "Genome Medicine", |
| "last_author": "Andrew E. Teschendorff", |
| "model_type": "mean aggregation", |
| "n_features": 678, |
| "notes": "Pyaging returns an inverted HypoClock burden score, 1 minus the mean beta value across 678 solo-WCGW CpGs; higher values therefore indicate deeper PMD hypomethylation. The assigned 2018 paper is the biological precursor, while the named 678-site implementation is from 2020.", |
| "platform": [ |
| "Illumina 450K" |
| ], |
| "population": "human, age unspecified", |
| "postprocess": "one_minus", |
| "predicts": [ |
| "mitotic age" |
| ], |
| "preprocess": "mean", |
| "reference_values": true, |
| "research_only": null, |
| "species": "Homo sapiens", |
| "tissue": [ |
| "multi-tissue" |
| ], |
| "training_target": [ |
| "not applicable" |
| ], |
| "unit": [ |
| "beta value" |
| ], |
| "version": "0.5.0", |
| "year": 2020 |
| } |