metadata
license: mit
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
hypoclock
Pyaging returns an inverted HypoClock burden score, 1 minus the mean beta value across 678 solo-WCGW CpGs; higher values therefore indicate deeper PMD hypomethylation. The assigned 2018 paper is the biological precursor, while the named 678-site implementation is from 2020.
| Predicts | mitotic age |
| Species | Homo sapiens |
| Tissue | multi-tissue |
| Data type | DNA methylation |
| Model type | mean aggregation |
| Year | 2020 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["hypoclock"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Teschendorff, Andrew E. "A comparison of epigenetic mitotic-like clocks for cancer risk prediction." Genome Medicine 12 (2020): 56.