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metadata
license: mit
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

grimage2

Mortality-risk epigenetic clock combining ten blood DNAm surrogate biomarkers with chronological age and sex; the Cox linear predictor is calibrated to an age-like value in years.

Predicts mortality risk
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type elastic net Cox regression
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["grimage2"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lu, A. T., et al. “DNA methylation GrimAge version 2.” Aging 14(23): 9484–9549 (2022).

https://doi.org/10.18632/aging.204434