dnamfili

Epigenetic frailty risk score (eFRS), a weighted 20-CpG whole-blood DNA-methylation score selected by LASSO from replicated frailty-associated loci.

Predicts frailty risk
Species Homo sapiens
Tissue whole blood
Data type DNA methylation
Model type LASSO regression
Year 2022

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["dnamfili"])

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Citation

Li, X. et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications 13, 5269 (2022).

https://doi.org/10.1038/s41467-022-32893-x

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