| { |
| "approved_by_author": "\u231b", |
| "citation": "Shireby, G. L., et al. \"Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.\" Brain 143.12 (2020): 3763-3775.", |
| "citations": 206, |
| "citations_date": "2026-07-05", |
| "clock_name": "corticalclock", |
| "data_type": "DNA methylation", |
| "doi": "https://doi.org/10.1093/brain/awaa334", |
| "journal": "Brain", |
| "last_author": "Jonathan Mill", |
| "model_type": "elastic net regression", |
| "n_features": 347, |
| "notes": "Cortex-specific DNA-methylation chronological-age estimator trained by elastic net on 1,047 post-mortem cortical samples; its 347-CpG weighted score is back-transformed to years.", |
| "platform": [ |
| "Illumina 450K" |
| ], |
| "population": "human, age unspecified", |
| "postprocess": "anti_log_linear", |
| "predicts": [ |
| "chronological age" |
| ], |
| "reference_values": true, |
| "research_only": null, |
| "species": "Homo sapiens", |
| "tissue": [ |
| "brain cortex" |
| ], |
| "training_target": [ |
| "chronological age" |
| ], |
| "unit": [ |
| "years" |
| ], |
| "version": "0.5.0", |
| "year": 2020 |
| } |
