Training mRNA Language Models Across 25 Species for $165
• 28
AI & ML interests
healthcare AI, clinical NER, biomedical NLP, PII / de-identification, on-device AI, edge inference, Apple Silicon / MLX, data sovereignty, privacy-preserving ML, open-source
Recent Activity
View all activity
Articles
Transformers support
1
#1 opened 11 days ago
by 
Praba-854
MaziyarPanahi
updated a
collection 12 days ago
MaziyarPanahi
posted an update 4 months ago
Post
4629
Training mRNA Language Models Across 25 Species for $165
We built an end-to-end protein AI pipeline covering structure prediction, sequence design, and codon optimization. After comparing multiple transformer architectures for codon-level language modeling, CodonRoBERTa-large-v2 emerged as the clear winner with a perplexity of 4.10 and a Spearman CAI correlation of 0.40, significantly outperforming ModernBERT. We then scaled to 25 species, trained 4 production models in 55 GPU-hours, and built a species-conditioned system that no other open-source project offers. Complete results, architectural decisions, and runnable code below.
https://huggingface.co/blog/OpenMed/training-mrna-models-25-species
We built an end-to-end protein AI pipeline covering structure prediction, sequence design, and codon optimization. After comparing multiple transformer architectures for codon-level language modeling, CodonRoBERTa-large-v2 emerged as the clear winner with a perplexity of 4.10 and a Spearman CAI correlation of 0.40, significantly outperforming ModernBERT. We then scaled to 25 species, trained 4 production models in 55 GPU-hours, and built a species-conditioned system that no other open-source project offers. Complete results, architectural decisions, and runnable code below.
https://huggingface.co/blog/OpenMed/training-mrna-models-25-species
MaziyarPanahi
posted an update 4 months ago
Post
2399
We annotated 119K medical images with two frontier VLMs (Qwen 3.5, Kimi K2.5), cross-validated at 93% agreement, and produced 110K training records, all for under $500. Fine-tuning 3 small models (2-3B params) improved all benchmarks: best model reaches +15.0% average exact match.
Everything is open-sourced: datasets, adapters, and code.
https://huggingface.co/blog/OpenMed/synthvision
Everything is open-sourced: datasets, adapters, and code.
https://huggingface.co/blog/OpenMed/synthvision
- 2 replies