opig/p-IgGen

Model Card for Model ID

Auto-regressive protein language model for paired antibody library generation.

Pretrained on unpaired heavy and light chain sequences from the Observed Antibody Space (OAS), and finetuned on paired sequences.

Getting Started?

This model was featured in the Hugging Face blog How to Train an Antibody Developability Model (found here: https://huggingface.co/blog/ginkgo-datapoints/making-antibody-embeddings-and-predictions). Sample code on how to get started using this model can be found in the blog.

Model Details

Model Description

• Funded by: EPSRC, AstraZeneca
• License: BSD-3-Clause license

Model Sources

Note: This is a duplicate of Ollie Turnbull's model repo, found here: https://huggingface.co/ollieturnbull/p-IgGen

• Repository: https://github.com/OliverT1/p-IgGen
• Paper: https://academic.oup.com/bioinformatics/article/40/11/btae659/7888884