Split (2)

train · 48.9k rows

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.

ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_42500	A mutation has occurred on Chromosome 12. What is the medical relevance of this mutation?	Benign	AAATATTAATAACAGCTTTAGTTGTAATAATAAAAAATTGGAAGCAATCCAAATGTCCTTCAACAGGTAAATGAATAAACAAACTGTGGTACGTCCATACAATTGAAATTATTCAGCAATAAAAAGGAACTACAGATATACGCCACAACATGGATAAATCTCAAAATCATGATGCTGTGAAAGAAGCTAAGCTAAAAAGGAGCCATTGCTCATAGGTCCTAGCTCTGTTTTTGGCTCATGCTGTGAATTCTCCCTCCTCTCAACTCTCCAGGGCCCAATTTTCATCTCCAATTATGAAAGTTTTTCCTGGCCTTCAAAAT...	AAATATTAATAACAGCTTTAGTTGTAATAATAAAAAATTGGAAGCAATCCAAATGTCCTTCAACAGGTAAATGAATAAACAAACTGTGGTACGTCCATACAATTGAAATTATTCAGCAATAAAAAGGAACTACAGATATACGCCACAACATGGATAAATCTCAAAATCATGATGCTGTGAAAGAAGCTAAGCTAAAAAGGAGCCATTGCTCATAGGTCCTAGCTCTGTTTTTGGCTCATGCTGTGAATTCTCCCTCCTCTCAACTCTCCAGGGCCCAATTTTCATCTCCAATTATGAAAGTTTTTCCTGGCCTTCAAAAT...
Task1_train_42501	This variant is found on Chromosome 12. What is the clinical effect of this variant — benign or pathogenic? State the disease if applicable.	Benign	TTTTAGTAGAGACGGGGTTTCTCCATATTGGTCATGCTGGTCTTGAACTCCCAACCTCAGGTGATCGGCCCACCTCAGCCTCCCAACGTATTGGGATTACAGGCTTGAGCCACTGCACCCGGCCTTGGTTGTTTTCTTTAATTAATTTTTTATAGAGACGGGGTCTTGCTATGTTAGTCAGGCTGGTCTCAAACTCATGGCCTCAAGTGATCCTCCTGCCCTGGCCTCCCAAAGTGCTGGGATCATAGGCGTATGTGCTGGGACTATAACATCATGCCTGCTAGCTATTTCTTTAGAAAAATGAGAAGAAGGCCGGGCGT...	TTTTAGTAGAGACGGGGTTTCTCCATATTGGTCATGCTGGTCTTGAACTCCCAACCTCAGGTGATCGGCCCACCTCAGCCTCCCAACGTATTGGGATTACAGGCTTGAGCCACTGCACCCGGCCTTGGTTGTTTTCTTTAATTAATTTTTTATAGAGACGGGGTCTTGCTATGTTAGTCAGGCTGGTCTCAAACTCATGGCCTCAAGTGATCCTCCTGCCCTGGCCTCCCAAAGTGCTGGGATCATAGGCGTATGTGCTGGGACTATAACATCATGCCTGCTAGCTATTTCTTTAGAAAAATGAGAAGAAGGCCGGGCGT...
Task1_train_42502	A mutation on Chromosome 12 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	GCCTGTTGGGTACAGTGTTTGGTTTAGAGTTGTGCTCAAGAAACAGTAATTCTGAGGCCAGGCAAAATGGCTCATGCCTGTAATCCCAGCACTTTAGGAGGCCGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAATATGGCAAAACTCCATCTCTACTAAAATACAAAAATTAGCTGGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCGCCACTGCTCTCCAGCCTGGGCAACAG...	GCCTGTTGGGTACAGTGTTTGGTTTAGAGTTGTGCTCAAGAAACAGTAATTCTGAGGCCAGGCAAAATGGCTCATGCCTGTAATCCCAGCACTTTAGGAGGCCGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAATATGGCAAAACTCCATCTCTACTAAAATACAAAAATTAGCTGGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCGCCACTGCTCTCCAGCCTGGGCAACAG...
Task1_train_42503	Here is a genetic alteration on Chromosome 12. Based on the data, is it a benign variant or a cause of disease?	Benign	GCATTTAGTCATTATTTCTCTCTTCCTCCCTTTTTAACTTTATTATTTATTTATTTATTTGAGACAGAGTCTCACTCGGTCACTCAGGCTGGAGTGCAGTGACATGATCTCAGCTCATTGCAACCTCTGCCTCCCCGGTTCAAGCGATTCTCCTGCGTCAGCCTCCCAGGTAGCTGGGATTACAAGTGTGTGGCACTGTGCCTTGGTAACTTTTGTATTTTTAGTAGAGACGGTGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAG...	GCATTTAGTCATTATTTCTCTCTTCCTCCCTTTTTAACTTTATTATTTATTTATTTATTTGAGACAGAGTCTCACTCGGTCACTCAGGCTGGAGTGCAGTGACATGATCTCAGCTCATTGCAACCTCTGCCTCCCCGGTTCAAGCGATTCTCCTGCGTCAGCCTCCCAGGTAGCTGGGATTACAAGTGTGTGGCACTGTGCCTTGGTAACTTTTGTATTTTTAGTAGAGACGGTGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAG...
Task1_train_42504	This mutation is located on Chromosome 12. Is it associated with a disease or is it a benign polymorphism?	Benign	TTAATAGTGTCATTTGATACATAGAAGTTTTAGATTTTGATGGCATCTTGTTTTATTTATTTATTTTTATTTTTTTGAGACAGGGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAGTCACAGCTCACTGCAGCCTTGACCTCCCTTGAGCAATCCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTATAGGTGCACACCACCATGCCTCGCTAATTTTTATACTTTTTGTAGAGTCAGGGTTTCACCATGCCCAGCCTGGTCTTCAACTCCTGGGCTCAAGTGATCTTCCTGCCTCCCAAAGTGCTGGGATTA...	TTAATAGTGTCATTTGATACATAGAAGTTTTAGATTTTGATGGCATCTTGTTTTATTTATTTATTTTTATTTTTTTGAGACAGGGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAGTCACAGCTCACTGCAGCCTTGACCTCCCTTGAGCAATCCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTATAGGTGCACACCACCATGCCTCGCTAATTTTTATACTTTTTGTAGAGTCAGGGTTTCACCATGCCCAGCCTGGTCTTCAACTCCTGGGCTCAAGTGATCTTCCTGCCTCCCAAAGTGCTGGGATTA...
Task1_train_42505	This alteration on Chromosome 12 may affect genome function. Does it lead to a disease or is it benign?	Benign	CATACACACGCACACACACACACATGATTAGGATGATGCGATTGTTTTGCAGTGTGCTTTTTTCACAAATTTTGGTCACTTTCCCAATCTACCTCATTCTTTTTGAAGGCAGCAAAGTTTTTATTTTTATTTCTATTTTTTATTTTTATGTCTTTATTTTTTTTTGAGATGGAGTTTCACTTTTGTTCCCCGGCTGGAGTGCAATGGTGTAATCTTGGCTCACTGCAAACTCCGCCTCCTGGGTTCAAGTGATTCTCCTACCTCAGCTTCCCGAGTAGCTGGGATTATAGGTGCCTACCACCACACCTGGCTAATTTTTT...	CATACACACGCACACACACACACATGATTAGGATGATGCGATTGTTTTGCAGTGTGCTTTTTTCACAAATTTTGGTCACTTTCCCAATCTACCTCATTCTTTTTGAAGGCAGCAAAGTTTTTATTTTTATTTCTATTTTTTATTTTTATGTCTTTATTTTTTTTTGAGATGGAGTTTCACTTTTGTTCCCCGGCTGGAGTGCAATGGTGTAATCTTGGCTCACTGCAAACTCCGCCTCCTGGGTTCAAGTGATTCTCCTACCTCAGCTTCCCGAGTAGCTGGGATTATAGGTGCCTACCACCACACCTGGCTAATTTTTT...
Task1_train_42506	This mutation on Chromosome 12 may be significant. Is it associated with any clinical condition, or is it benign?	Benign	GCTAATTTTTCATAGAGACAGGAAACTACTATGTTGCCCAGGCTGGACTCGAACTCCTAACCCCAAGCAATCCTCCCACCTTAGCCTCCCAAAGTGCTGGGATTATGGGAATGAGCCACTGCGTTCTGCCCATGACCAGAGTCTTAAAACCTATGTTGAGATTTATGGAATTTTAAAAACTCTTCCCTTCCCTCCCCTCCCCTCCCCTCCCCTTCCCTCCCCTCCCCTCCCCTCTCCTTCCCTCCCCTTCCCTCCCCTCCCCTTCCCTCCCCTCCCCTCCCCTTCCCTCCCCTCCCCCTCCCCCTCCCCTTCTTCTTCCT...	GCTAATTTTTCATAGAGACAGGAAACTACTATGTTGCCCAGGCTGGACTCGAACTCCTAACCCCAAGCAATCCTCCCACCTTAGCCTCCCAAAGTGCTGGGATTATGGGAATGAGCCACTGCGTTCTGCCCATGACCAGAGTCTTAAAACCTATGTTGAGATTTATGGAATTTTAAAAACTCTTCCCTTCCCTCCCCTCCCCTCCCCTCCCCTTCCCTCCCCTCCCCTCCCCTCTCCTTCCCTCCCCTTCCCTCCCCTCCCCTTCCCTCCCCTCCCCTCCCCTTCCCTCCCCTCCCCCTCCCCCTCCCCTTCTTCTTCCT...
Task1_train_42507	Here is a mutation located on Chromosome 12. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	TGACGTGTTGAGCCTGCCAGTCCACAGAAGTCAAGAATTGGGGTTTGGGAACCTCTGCCTAGATTTCAGAAGGTGTATGGAAACACCTTGATGCCCAGGCAGAAGTTTGTTGCAGGGGCGGGGCCCTCATGGAGCACCTCTGCTAGAGCAGTGTGGAAGGGAAATGTGGGGTCAGAGCCCCCACACAGAGTCTCTACTGGGGCACTGCCTAGTGGAGCTGTGAGAAGAGGGCCACCATCCTCCAGACCTCAGGATGGTAGATCCACTGACAGCTTGCACTGTTTGCCTGGAAAAGCCATAGACACTAATGCCAGCCCATG...	TGACGTGTTGAGCCTGCCAGTCCACAGAAGTCAAGAATTGGGGTTTGGGAACCTCTGCCTAGATTTCAGAAGGTGTATGGAAACACCTTGATGCCCAGGCAGAAGTTTGTTGCAGGGGCGGGGCCCTCATGGAGCACCTCTGCTAGAGCAGTGTGGAAGGGAAATGTGGGGTCAGAGCCCCCACACAGAGTCTCTACTGGGGCACTGCCTAGTGGAGCTGTGAGAAGAGGGCCACCATCCTCCAGACCTCAGGATGGTAGATCCACTGACAGCTTGCACTGTTTGCCTGGAAAAGCCATAGACACTAATGCCAGCCCATG...
Task1_train_42508	A mutation on Chromosome 12 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	CAAGCTCCGCCTGCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGGCTAATTATTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCCATCTCCTGACCTCGTGATCCGCCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCCGGCCTAATTTTTTTATTTTAATTTTTTTATTTTAATTTTTTATTTTAATTTTTTTTTGAGATGGAGTTTCACTCTGTTGCCCAGGCTAGAGTGCTGTGCGTG...	CAAGCTCCGCCTGCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGGCTAATTATTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCCATCTCCTGACCTCGTGATCCGCCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCCGGCCTAATTTTTTTATTTTAATTTTTTTATTTTAATTTTTTATTTTAATTTTTTTTTGAGATGGAGTTTCACTCTGTTGCCCAGGCTAGAGTGCTGTGCGTG...
Task1_train_42509	A mutation has occurred on Chromosome 12. What is the medical relevance of this mutation?	Benign	CTGCTGTGCGCCCTTCTCGGTGAATGGCACCGCCGCCCGCCCGGGCCTCTCGTCCACAGCCCGCGGTGCTCGCACACCTGAGACTCATCTCGCTTCGACCCCGCCGCCGCCGCCGCCCGGCATCCTGAGCACGGAGACAGTCTCCAGCTGCCGTTCATGCTTCCTCCCCAGCCTTCCGCAGCCCACCAGGGAAGGGGCGGTAGGAGTGGCCTTTTACCAAAGGTCAGATTCTTTCACCGCCTCTGCCAGACCCCCTTGTCCCCCACCCCCGCATAGATCTCCAGGGGGCTCAGAAAACTCTGGCCGGTGGCTCACGCCTG...	CTGCTGTGCGCCCTTCTCGGTGAATGGCACCGCCGCCCGCCCGGGCCTCTCGTCCACAGCCCGCGGTGCTCGCACACCTGAGACTCATCTCGCTTCGACCCCGCCGCCGCCGCCGCCCGGCATCCTGAGCACGGAGACAGTCTCCAGCTGCCGTTCATGCTTCCTCCCCAGCCTTCCGCAGCCCACCAGGGAAGGGGCGGTAGGAGTGGCCTTTTACCAAAGGTCAGATTCTTTCACCGCCTCTGCCAGACCCCCTTGTCCCCCACCCCCGCATAGATCTCCAGGGGGCTCAGAAAACTCTGGCCGGTGGCTCACGCCTG...
Task1_train_42510	A mutation has occurred on Chromosome 12. What is the medical relevance of this mutation?	Benign	CAGTGATCAGGCCAAGTCACTGGAGCCCAAGGCCGCTGAGAATACAATTGGTCACTCCATATGCCTGTCTGGACACGTCTGTCTCTAAGGACACGCTTCTGAGAGGCTACCAGATGTCTACTCCATTTCAATAGTATCAACAACTAATCTAGCAAAAAGTATCAGTAATTGTTTTATGTTAGGAATTTTCATAAAGTGAATAATTTAAAATTTGTTAATAGAGCTATTTAAAGGAGTTATATAAGAAACTCTTTCAAAAGAGCAAATACCTTATCTAATACAGTCTTAAAAAGATTTGATTTTAGGGGCCAGGTCTCATG...	CAGTGATCAGGCCAAGTCACTGGAGCCCAAGGCCGCTGAGAATACAATTGGTCACTCCATATGCCTGTCTGGACACGTCTGTCTCTAAGGACACGCTTCTGAGAGGCTACCAGATGTCTACTCCATTTCAATAGTATCAACAACTAATCTAGCAAAAAGTATCAGTAATTGTTTTATGTTAGGAATTTTCATAAAGTGAATAATTTAAAATTTGTTAATAGAGCTATTTAAAGGAGTTATATAAGAAACTCTTTCAAAAGAGCAAATACCTTATCTAATACAGTCTTAAAAAGATTTGATTTTAGGGGCCAGGTCTCATG...
Task1_train_42511	A mutation on Chromosome 12 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	CGAGGCAGGCAGATCACAAGGTCAGGAGTCAATATGGTGAAACCCAGTCCCTACTAAAAATACAAAGCTTAGCCGGGTGTGGCAGCACGCACCTGTAGTCCCAGCTACTCAAGAGGGTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGGTCACACCACTGTACTCCAACCTGGGTGACAGAGCGAGACTCTTTTTTTTTTTTTTAGGCAGTCTCATTCTGTCACCAGGCTGGAGCGCAGTGGTGCAATCTCAGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGTGATTCTCCTGCCTC...	CGAGGCAGGCAGATCACAAGGTCAGGAGTCAATATGGTGAAACCCAGTCCCTACTAAAAATACAAAGCTTAGCCGGGTGTGGCAGCACGCACCTGTAGTCCCAGCTACTCAAGAGGGTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGGTCACACCACTGTACTCCAACCTGGGTGACAGAGCGAGACTCTTTTTTTTTTTTTTAGGCAGTCTCATTCTGTCACCAGGCTGGAGCGCAGTGGTGCAATCTCAGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGTGATTCTCCTGCCTC...
Task1_train_42512	A mutation has occurred on Chromosome 12. What is the medical relevance of this mutation?	Benign	ATCTCAGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGAACTACAGGCCCACATCACCACACCGGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTTGATCTTCTGATCTCGTGATCCGCCTGCAACAGCCTCCCAAAGTGCTGGGATTACAGGTGTAAGCCACCGCACCCGGTGAGACTCTGTCTTAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAGTCCTTTAGGCACTTGTTTATAATTTATTGGTCTA...	ATCTCAGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGAACTACAGGCCCACATCACCACACCGGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTTGATCTTCTGATCTCGTGATCCGCCTGCAACAGCCTCCCAAAGTGCTGGGATTACAGGTGTAAGCCACCGCACCCGGTGAGACTCTGTCTTAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAGTCCTTTAGGCACTTGTTTATAATTTATTGGTCTA...
Task1_train_42513	This variant is located on Chromosome 12. Evaluate its biological effect and specify any disease association.	Benign	GGATTACAGGTGTAAGCCACCGCACCCGGTGAGACTCTGTCTTAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAGTCCTTTAGGCACTTGTTTATAATTTATTGGTCTAATAAAGTTTATGAAAATTCTGCATTTTTCCCTATCCAATTATCAGCCATGAAGATTTCAATGGAATCTTCCAACTCCAAATGGACAGACACAATGAAATAGTTAAAAGCCAAACAGAAGACTATATTTCAATATGTGCCAATTTATTGCTTTTTTTTTTTTTCCCTTGAGACAGAGTTTTTCACTCTTGTTGCCCAGGCTGGA...	GGATTACAGGTGTAAGCCACCGCACCCGGTGAGACTCTGTCTTAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAGTCCTTTAGGCACTTGTTTATAATTTATTGGTCTAATAAAGTTTATGAAAATTCTGCATTTTTCCCTATCCAATTATCAGCCATGAAGATTTCAATGGAATCTTCCAACTCCAAATGGACAGACACAATGAAATAGTTAAAAGCCAAACAGAAGACTATATTTCAATATGTGCCAATTTATTGCTTTTTTTTTTTTTCCCTTGAGACAGAGTTTTTCACTCTTGTTGCCCAGGCTGGA...
Task1_train_42514	Given this variant on Chromosome 12, classify it as benign or pathogenic. Include the disorder it may cause if applicable.	Benign	CTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCAGAACTGGCTACAAATTTACATTTGAATGGCCTCACATGGCTGGTGGCTACTACATTAGGCAGCACAGCTATAGCCCACTGGCTCTTAAAAGTAGGGAATAGGAGGCTTCATGGGTTCCAGGAACCTTGTTGAGTGCACACGTAAACTTTCCTGAAAAAATATCTGTAGATTTCATTAGATTATTCCAAAGAGTCTGGGACTGATTACGATCCACTGAAATTAGATACTAGACACGTTTGGAGGGGAACAGTCCTGGCATTTTTAACTCAATGACTCTTGCACAA...	CTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCAGAACTGGCTACAAATTTACATTTGAATGGCCTCACATGGCTGGTGGCTACTACATTAGGCAGCACAGCTATAGCCCACTGGCTCTTAAAAGTAGGGAATAGGAGGCTTCATGGGTTCCAGGAACCTTGTTGAGTGCACACGTAAACTTTCCTGAAAAAATATCTGTAGATTTCATTAGATTATTCCAAAGAGTCTGGGACTGATTACGATCCACTGAAATTAGATACTAGACACGTTTGGAGGGGAACAGTCCTGGCATTTTTAACTCAATGACTCTTGCACAA...
Task1_train_42515	A mutation on Chromosome 12 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	AGTTTCGCTCCCTCCCTTCCTTTTTATTATTTATTTATTTTTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCACTATCTCAGCTCACCGCAACCTCCACCTCCCGGGTCCAACTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGAATGCGCCACCATACCCGGCTAATTTTGTATCTTTAGTAGAGACGGGGTTTTCCATGTTGGTCAGGCTGTTCTTGAACTCCCAACCTCAGGTGATCCGCCTACCTCGGCCTCCCAAAGTGCAGGGAGATTACAGACATGAGCTACA...	AGTTTCGCTCCCTCCCTTCCTTTTTATTATTTATTTATTTTTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCACTATCTCAGCTCACCGCAACCTCCACCTCCCGGGTCCAACTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGAATGCGCCACCATACCCGGCTAATTTTGTATCTTTAGTAGAGACGGGGTTTTCCATGTTGGTCAGGCTGTTCTTGAACTCCCAACCTCAGGTGATCCGCCTACCTCGGCCTCCCAAAGTGCAGGGAGATTACAGACATGAGCTACA...
Task1_train_42516	This variant lies on Chromosome 12. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	CTGAAAATTATCATACTCTTGGTTGTCTCAGTCTTGTGGCTGGAGATTTAGCAAGTGAAGTTCCTGTGATAATTGGGGTAATTGTTTTTATAAAGTTTTGTTTTTTGTTGCCTAAAGCATTTTCTCAGAAAAATGTTTTTGTTTTGGTTAAATTGCAAAATAATTTGTAACATATAACCGAAACAAGGAAATTATAAAATTAAGGTAATTAAAAATAACTCAATAAATAAATTTCTGTCTTGGAAAAAATATTGCATCTTTACTTTCCCTAGTCTTTACCTGAAAGTACAGCATTTTTTTCAATTATGAGAGCAGACAAA...	CTGAAAATTATCATACTCTTGGTTGTCTCAGTCTTGTGGCTGGAGATTTAGCAAGTGAAGTTCCTGTGATAATTGGGGTAATTGTTTTTATAAAGTTTTGTTTTTTGTTGCCTAAAGCATTTTCTCAGAAAAATGTTTTTGTTTTGGTTAAATTGCAAAATAATTTGTAACATATAACCGAAACAAGGAAATTATAAAATTAAGGTAATTAAAAATAACTCAATAAATAAATTTCTGTCTTGGAAAAAATATTGCATCTTTACTTTCCCTAGTCTTTACCTGAAAGTACAGCATTTTTTTCAATTATGAGAGCAGACAAA...
Task1_train_42517	This mutation is located on Chromosome 12. Is it associated with a disease or is it a benign polymorphism?	Benign	CACTGCGCCTGAACAAGAATTTTTAGAACTAAGATAAAATGTGTTATTTATAGATTCCGCTGACTTTGATAAGTAGGGATAAATGATTTGTAATTTATATCTCAGATGTTTCTGTCTAGTAAATACAAGGACTCGTTTTCTGGTTTCAGAATGCTTTCAGATCTGTCACCTCATTTAATTTTTATAGTTCTTATTGCATATGTTGCCAGTTGATATATGAGAAAACAACATAGTATGTGACCTGCTCAAGGTCAAATTATTAATGACTGCTTCTAAAATATTATGGGTGCTATAACCTCCATCTGATTTGTAACAGATTA...	CACTGCGCCTGAACAAGAATTTTTAGAACTAAGATAAAATGTGTTATTTATAGATTCCGCTGACTTTGATAAGTAGGGATAAATGATTTGTAATTTATATCTCAGATGTTTCTGTCTAGTAAATACAAGGACTCGTTTTCTGGTTTCAGAATGCTTTCAGATCTGTCACCTCATTTAATTTTTATAGTTCTTATTGCATATGTTGCCAGTTGATATATGAGAAAACAACATAGTATGTGACCTGCTCAAGGTCAAATTATTAATGACTGCTTCTAAAATATTATGGGTGCTATAACCTCCATCTGATTTGTAACAGATTA...
Task1_train_42518	Here is a variant on Chromosome 12. Please identify whether it is a benign mutation or associated with a disorder.	Benign	GATCTCGGCTCATTGCAAGCTCCGCCTGCTGGGTTCACGCTATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCATGCCGCCACGCCCTGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCCGGCCGAGATTTCCTGTTTTACAGGCATGTATGCTATGTGTGTGCATATCTACAGTGTATATATGCATTTTTGCACACATAAATGCAATC...	GATCTCGGCTCATTGCAAGCTCCGCCTGCTGGGTTCACGCTATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCATGCCGCCACGCCCTGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCCGGCCGAGATTTCCTGTTTTACAGGCATGTATGCTATGTGTGTGCATATCTACAGTGTATATATGCATTTTTGCACACATAAATGCAATC...
Task1_train_42519	A genetic alteration is present on Chromosome 12. Is this variant benign or disease-causing, and if the latter, which condition is involved?	Benign	TCCTTGCTTTTGGCTTTTTACCTGTACATTGCTTGGTGATACAGACAAGCCAACTGCTCTGAAAGCACAGAGGTAATTCCAGAGCATCCACCTTTCTTCATTTACTGTCATTCACCCAGAGCTGGGAGCCTGTCTCTAAATTCCTTATCTGTGTTCATGTCAGGAGGTTGAAGCAAGCCTCGTCTTGCCAAATAATCAAGGACTGACAGAGTTAGAAATGAAAGCGTAACAGAAACTTGGACTGATCACAGACTCAAACCAGTACATCTCCTTTCCTTCTCTGAATTGGGAACTGAAACCATTCCATAGGAAGCTCGCTC...	TCCTTGCTTTTGGCTTTTTACCTGTACATTGCTTGGTGATACAGACAAGCCAACTGCTCTGAAAGCACAGAGGTAATTCCAGAGCATCCACCTTTCTTCATTTACTGTCATTCACCCAGAGCTGGGAGCCTGTCTCTAAATTCCTTATCTGTGTTCATGTCAGGAGGTTGAAGCAAGCCTCGTCTTGCCAAATAATCAAGGACTGACAGAGTTAGAAATGAAAGCGTAACAGAAACTTGGACTGATCACAGACTCAAACCAGTACATCTCCTTTCCTTCTCTGAATTGGGAACTGAAACCATTCCATAGGAAGCTCGCTC...
Task1_train_42520	Here’s a variant located on Chromosome 12. What is the predicted biological effect — harmless or disease-causing?	Benign	TCCCTTGAACGAATCCGCGTTTCACAACGAGGCTCCCCACTGACTCATGCCTCCGAGGCTGGGGAATCCCTATTTTCCTCTGAGCTCATCCCTGACATCTCTTCCTCTTTAAGGTGATCCTTGCTTTTGGCTTTTTACCTGTACATTGCTTGGTGATACAGACAAGCCAACTGCTCTGAAAGCACAGAGGTAATTCCAGAGCATCCACCTTTCTTCATTTACTGTCATTCACCCAGAGCTGGGAGCCTGTCTCTAAATTCCTTATCTGTGTTCATGTCAGGAGGTTGAAGCAAGCCTCGTCTTGCCAAATAATCAAGGAC...	TCCCTTGAACGAATCCGCGTTTCACAACGAGGCTCCCCACTGACTCATGCCTCCGAGGCTGGGGAATCCCTATTTTCCTCTGAGCTCATCCCTGACATCTCTTCCTCTTTAAGGTGATCCTTGCTTTTGGCTTTTTACCTGTACATTGCTTGGTGATACAGACAAGCCAACTGCTCTGAAAGCACAGAGGTAATTCCAGAGCATCCACCTTTCTTCATTTACTGTCATTCACCCAGAGCTGGGAGCCTGTCTCTAAATTCCTTATCTGTGTTCATGTCAGGAGGTTGAAGCAAGCCTCGTCTTGCCAAATAATCAAGGAC...
Task1_train_42521	Assess the clinical impact of this variant found on Chromosome 12. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	CTATGGAAAAATATCTGCCTGGCTTGATTCCCTTTTTATATTATTTATTATTATTATTTGAGATGAAGTCTTGCTCTGTCCCCCAGGCTGGAGTGCAGGCACACCACCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTTCTTCTCCCAGCCTTCCCAGTAGCTGGGACTACAAGCGGCCGCCACCATGCCTGGCTAATTTTTCTTGTATTTTTAGTAGAAGTGGGGTTTCACCATTTTGTCCAGGCTGGTCTCAAACTCCTTACTTCAGGTGATCTGCCCGCCTTGGCTCCCCCAAAGTGCTGGGATT...	CTATGGAAAAATATCTGCCTGGCTTGATTCCCTTTTTATATTATTTATTATTATTATTTGAGATGAAGTCTTGCTCTGTCCCCCAGGCTGGAGTGCAGGCACACCACCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTTCTTCTCCCAGCCTTCCCAGTAGCTGGGACTACAAGCGGCCGCCACCATGCCTGGCTAATTTTTCTTGTATTTTTAGTAGAAGTGGGGTTTCACCATTTTGTCCAGGCTGGTCTCAAACTCCTTACTTCAGGTGATCTGCCCGCCTTGGCTCCCCCAAAGTGCTGGGATT...
Task1_train_42522	Consider this mutation on Chromosome 12. Is this a benign change or a disease-causing variant?	Benign	AGTCGTACTCTGCCGTGTGGACAGACCACATTGTGTTTATCTGTTCATCACTTGGTGGACATTGGGTTTGTTGCAACTTTCTGGCTGTTGTAAATAGTGCTGCTGTGGGCCTTTGAGCACAAGTTTCTGTGTAAACATCTGCCATCACTTATCTTGGATAGATAGCTGATGTGTGTGGAACACAGTAGAACTGCTGGGTCTCACCTCTGTTACCCTGTTGAGAAACTACCAGACTGTTTTCCAAAGTGGCTGCACCATTTTACACTCCCACCAGCAACGCATGAATGTTCCAGTTTCTCCACATCCTTGCCAATGCTTAT...	AGTCGTACTCTGCCGTGTGGACAGACCACATTGTGTTTATCTGTTCATCACTTGGTGGACATTGGGTTTGTTGCAACTTTCTGGCTGTTGTAAATAGTGCTGCTGTGGGCCTTTGAGCACAAGTTTCTGTGTAAACATCTGCCATCACTTATCTTGGATAGATAGCTGATGTGTGTGGAACACAGTAGAACTGCTGGGTCTCACCTCTGTTACCCTGTTGAGAAACTACCAGACTGTTTTCCAAAGTGGCTGCACCATTTTACACTCCCACCAGCAACGCATGAATGTTCCAGTTTCTCCACATCCTTGCCAATGCTTAT...
Task1_train_42523	A variant was discovered on Chromosome 12. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	GTGAATAACTTCCCAGACACTTATCTCCAGGGCAGGGTGCCTTCCAGTAGCCAAGGGAAGCCTCCAGAGAGCACAGATGTGAACCCTCAGCAGCAGGCATCACCCCCCAGTGGACTCGGGTGGGCCACCAGTAGCATCTTCTAGATGGCAGAGGGGTGAATGGCAGGGCCAGGAACCAGGCTGCCCGGGTTCCCATTCTGCTTCTGCCACTTCCAGCTGTGTGGCTTTAGGTGAGCCTTCACCTTTTGGTGCCTTCGTTTCCTCATTTAGCACCTACCTCCTAGAGCTGTTTTGGGAGTCAAATGCGCTGACGTATATAA...	GTGAATAACTTCCCAGACACTTATCTCCAGGGCAGGGTGCCTTCCAGTAGCCAAGGGAAGCCTCCAGAGAGCACAGATGTGAACCCTCAGCAGCAGGCATCACCCCCCAGTGGACTCGGGTGGGCCACCAGTAGCATCTTCTAGATGGCAGAGGGGTGAATGGCAGGGCCAGGAACCAGGCTGCCCGGGTTCCCATTCTGCTTCTGCCACTTCCAGCTGTGTGGCTTTAGGTGAGCCTTCACCTTTTGGTGCCTTCGTTTCCTCATTTAGCACCTACCTCCTAGAGCTGTTTTGGGAGTCAAATGCGCTGACGTATATAA...
Task1_train_42524	Chromosome 12 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	GTCTCAAACTCCAGAGCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGAATTACAGGCCTGAGCCACTGCACCCAGCCAATACTTACTATATTCAATGATAAAATAATAAAAACACGTACAATATTCAGTATGTACAATTACTAAAAAATACAGAATGACAATACTCAATGGACATGACTTATATTAAAAGGAAAAAGACTCTTCTAAAGCTTAATCTAAATATACAGGCATTGTTCTTTTCACTGAGAAGCATCTCAGTAAAACATACCTTATCTCCATCCATAAATCGTTGTTTTTCTGTGATGTTTAGTA...	GTCTCAAACTCCAGAGCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGAATTACAGGCCTGAGCCACTGCACCCAGCCAATACTTACTATATTCAATGATAAAATAATAAAAACACGTACAATATTCAGTATGTACAATTACTAAAAAATACAGAATGACAATACTCAATGGACATGACTTATATTAAAAGGAAAAAGACTCTTCTAAAGCTTAATCTAAATATACAGGCATTGTTCTTTTCACTGAGAAGCATCTCAGTAAAACATACCTTATCTCCATCCATAAATCGTTGTTTTTCTGTGATGTTTAGTA...
Task1_train_42525	A variant found on Chromosome 12 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	CCACAGTCCTTTTCAGTGCCATATATGTTTTTATAAATTTATATATATATATAAATATATGTATATATATGTGTGTATATATATTAATATATATACACACATATGTGTATATATATATTAATATATATACACACATATGTGTATATATATACACACATATGTGTATATATATACACATATATGTATATATATAAATATATATATATACACACATATATGTATATATATATAAATATATATATACACACATATATGTATATATATAAAAATATATATATACACACATATATGTGTATATATACTTTTTTTTTTGAGACATA...	CCACAGTCCTTTTCAGTGCCATATATGTTTTTATAAATTTATATATATATATAAATATATGTATATATATGTGTGTATATATATTAATATATATACACACATATGTGTATATATATATTAATATATATACACACATATGTGTATATATATACACACATATGTGTATATATATACACATATATGTATATATATAAATATATATATATACACACATATATGTATATATATATAAATATATATATACACACATATATGTATATATATAAAAATATATATATACACACATATATGTGTATATATACTTTTTTTTTTGAGACATA...
Task1_train_42526	Assess the clinical impact of this variant found on Chromosome 12. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	TTACAAGAATGAGCCATCATGCCTGGCCCAAATATGCTGAATTTCTAGTAGTAAATACTGGCTGCTGGCTTCTGTAGTTTCTTCACAAAGAAGTAGATGGGCTTTTGGCAACTTGATTGTTTAGTAATGAGGCCACTCCTCACCCCTGTTCTGTTCTGTCCCATTGCTGGGATGGGCCAGGAGGCACAAATGTAGAGAGCACAGGCTGCAGGGGAGGCAGCACCATCAGGGCGAGGAGGCACCCACAGGCCAGTGCCACTGCTGACGGTACACTGGCCCACCAGCCCGGGGCTGGGGCTTTTCTTTCTCTTTTGCAATAA...	TTACAAGAATGAGCCATCATGCCTGGCCCAAATATGCTGAATTTCTAGTAGTAAATACTGGCTGCTGGCTTCTGTAGTTTCTTCACAAAGAAGTAGATGGGCTTTTGGCAACTTGATTGTTTAGTAATGAGGCCACTCCTCACCCCTGTTCTGTTCTGTCCCATTGCTGGGATGGGCCAGGAGGCACAAATGTAGAGAGCACAGGCTGCAGGGGAGGCAGCACCATCAGGGCGAGGAGGCACCCACAGGCCAGTGCCACTGCTGACGGTACACTGGCCCACCAGCCCGGGGCTGGGGCTTTTCTTTCTCTTTTGCAATAA...
Task1_train_42527	This sequence change occurs on Chromosome 12. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	TTACGAATTGCAAACTCACTGGGGCTGGGCTGGTGGTGGCAGTGGGGGGCCCTGGTGGGGTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCACTATCTCGGTTCACCGCAACCTCCACCTCCCGGGTTCAATGGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCCCAGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCCGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAG...	TTACGAATTGCAAACTCACTGGGGCTGGGCTGGTGGTGGCAGTGGGGGGCCCTGGTGGGGTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCACTATCTCGGTTCACCGCAACCTCCACCTCCCGGGTTCAATGGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCCCAGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCCGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAG...
Task1_train_42528	A variant was discovered on Chromosome 12. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	CTGTACTATCAGAGGAGCCTCAGGGTCCTAGGATCGGAGCTAGGGTTTTCAGTGTAAATGGAAGCACTGCTGTGTTAAAGCGAGAAAGCTGTGTTTATGAAATGAATAGATGAATGATTGTTGGGAAAAACTATTAACATGGACAGGAAACCTTAGTGTCAGCAACCAGGAGAGCTTGAGTGTTTTGTGTCTTTGGAAAACTCTGAAGATAGCAAAAGTTTGGAAAAAGAGGACCAAATTCAAAAGAGTTTTATTTTTATTTTATTTTATTTTATTTTTAGACAGAGTCTTGCTCTTGCCCAGGCTGGAATGCAGTGGCA...	CTGTACTATCAGAGGAGCCTCAGGGTCCTAGGATCGGAGCTAGGGTTTTCAGTGTAAATGGAAGCACTGCTGTGTTAAAGCGAGAAAGCTGTGTTTATGAAATGAATAGATGAATGATTGTTGGGAAAAACTATTAACATGGACAGGAAACCTTAGTGTCAGCAACCAGGAGAGCTTGAGTGTTTTGTGTCTTTGGAAAACTCTGAAGATAGCAAAAGTTTGGAAAAAGAGGACCAAATTCAAAAGAGTTTTATTTTTATTTTATTTTATTTTATTTTTAGACAGAGTCTTGCTCTTGCCCAGGCTGGAATGCAGTGGCA...
Task1_train_42529	Here is a mutation located on Chromosome 12. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	GCGAATTCAGAATCCTAACTCTGGGAAAGCGCTCTCTGGAAATGTAGTTTGATAATAGTGTCTTATAGGGGCCACGGGAATTTGTTTCTCTATAAAGCGATGGGCTCCAGTGTCATGTTACCAGAGTTATCGCTCAGTTTTGTTTGTTAAGGCTTTTGCTAGAACCTATTATGTATCCAGTTTTTAAAACATACTTCATTCCCTTGATAGCAGAGATCCAGAGCACAGATGGCAAGTTGTGTGGATGATACTGAATATGTTTATTTTCCTAAAGATAAATGTCACGACACGACATTTCTCAGTTTTTATTTAGATGTTTA...	GCGAATTCAGAATCCTAACTCTGGGAAAGCGCTCTCTGGAAATGTAGTTTGATAATAGTGTCTTATAGGGGCCACGGGAATTTGTTTCTCTATAAAGCGATGGGCTCCAGTGTCATGTTACCAGAGTTATCGCTCAGTTTTGTTTGTTAAGGCTTTTGCTAGAACCTATTATGTATCCAGTTTTTAAAACATACTTCATTCCCTTGATAGCAGAGATCCAGAGCACAGATGGCAAGTTGTGTGGATGATACTGAATATGTTTATTTTCCTAAAGATAAATGTCACGACACGACATTTCTCAGTTTTTATTTAGATGTTTA...
Task1_train_42530	Consider a variant on Chromosome 12. Determine its clinical classification and disease relevance.	Benign	ATGGGTTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGCGATTCACCCGCCTCGGCTTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCCGGCCTAATTTTTTTCTTTTAATTGTAGAGATGGGGTCTCCCTATGTTGCCCCGGCTGTTCTCGAACTCCTGGGCTCAAGAGATTTTCCCGCCTTGGCCTCTCAAAGTGCTGGATTACAGGCATAAGCTACCATGCCCAGCTTTTCAAATCCATGAATTTATAATGATCTTTAAAAGTCCTGATGGGTCATTTCTGGAGGATGATAGGGGACCA...	ATGGGTTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGCGATTCACCCGCCTCGGCTTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCCGGCCTAATTTTTTTCTTTTAATTGTAGAGATGGGGTCTCCCTATGTTGCCCCGGCTGTTCTCGAACTCCTGGGCTCAAGAGATTTTCCCGCCTTGGCCTCTCAAAGTGCTGGATTACAGGCATAAGCTACCATGCCCAGCTTTTCAAATCCATGAATTTATAATGATCTTTAAAAGTCCTGATGGGTCATTTCTGGAGGATGATAGGGGACCA...
Task1_train_42531	A genomic variant on Chromosome 12 is under review. What is the biological outcome — benign or pathogenic?	Benign	TGACACCCGGGCCAAGATAGAGGCTTCGGGGAGGGAAGATCGGTGGGAGTTTGACCGGAAGCGGCTGTTCGAGAGGACGGATTATATGGCCACCATCTGCCAGGACCTCTCCGACGTTCTGCAGGTAGGGGCTGGGCGAAGGCCGGCGGAATTTGCCCCGAAGAAGGCAGTTGGCTTTTGACAGTGGCCCCCTCCGTGTCAGGTAGGAGCTGGGCGTCAGAAAGGGCCTGGCAGGGAGAAGCCCTTCAAAGAAAGAACCTACGGAATATACTAGAATGTACCAGAATGGACCAGAGTACACCAGAGCTTTGCGACTTTTT...	TGACACCCGGGCCAAGATAGAGGCTTCGGGGAGGGAAGATCGGTGGGAGTTTGACCGGAAGCGGCTGTTCGAGAGGACGGATTATATGGCCACCATCTGCCAGGACCTCTCCGACGTTCTGCAGGTAGGGGCTGGGCGAAGGCCGGCGGAATTTGCCCCGAAGAAGGCAGTTGGCTTTTGACAGTGGCCCCCTCCGTGTCAGGTAGGAGCTGGGCGTCAGAAAGGGCCTGGCAGGGAGAAGCCCTTCAAAGAAAGAACCTACGGAATATACTAGAATGTACCAGAATGGACCAGAGTACACCAGAGCTTTGCGACTTTTT...
Task1_train_42532	A genomic variant on Chromosome 12 is under review. What is the biological outcome — benign or pathogenic?	Benign	AATCACCTTTACTTTTATTTTTTTAATTAAAAATGTAATTTGGAGGTAATTATAGATTCACATGCAGTTGTTAAGAATTACGACAGAGGGAGCCTTCGTACCCTTTAGTCATTTTCCCTAAGTAGTAACTTCTTGCAAAACTAGTTAAGATCACAACCAAGATATTGACATTGATACAGTCGAGATAGAGAGCATTTTCAACACCACAGCGAGTACTGTCAAGTCCACTTCCCTCCCATCCTTGCCCTCTCCTTAATCCCTGGCAACCATGAATCTTTATTCAATTTCTGTAATGTTGTCATTTCAGAGTGTTATATAAA...	AATCACCTTTACTTTTATTTTTTTAATTAAAAATGTAATTTGGAGGTAATTATAGATTCACATGCAGTTGTTAAGAATTACGACAGAGGGAGCCTTCGTACCCTTTAGTCATTTTCCCTAAGTAGTAACTTCTTGCAAAACTAGTTAAGATCACAACCAAGATATTGACATTGATACAGTCGAGATAGAGAGCATTTTCAACACCACAGCGAGTACTGTCAAGTCCACTTCCCTCCCATCCTTGCCCTCTCCTTAATCCCTGGCAACCATGAATCTTTATTCAATTTCTGTAATGTTGTCATTTCAGAGTGTTATATAAA...
Task1_train_42533	Located on Chromosome 12, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	TACAGGTGCACATCACCACACCCGGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTGCCGGCCTCGGCCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCAAAGCATTCGGCCTCCTACTCTTTTAAATTTATTTTGCCATTAACTGTAGGTCATCAAGATAATGACTATAGTAATCCGCAGTCACTTTTCCAGTATTGGCATTGTATTACTGTGTTTTCACACTGCTATACAGAAATACTCAAGACTGGGTAATTTATAAAGAAAAAGGT...	TACAGGTGCACATCACCACACCCGGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTGCCGGCCTCGGCCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCAAAGCATTCGGCCTCCTACTCTTTTAAATTTATTTTGCCATTAACTGTAGGTCATCAAGATAATGACTATAGTAATCCGCAGTCACTTTTCCAGTATTGGCATTGTATTACTGTGTTTTCACACTGCTATACAGAAATACTCAAGACTGGGTAATTTATAAAGAAAAAGGT...
Task1_train_42534	A variant was discovered on Chromosome 12. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	TCACTTTTCCAGTATTGGCATTGTATTACTGTGTTTTCACACTGCTATACAGAAATACTCAAGACTGGGTAATTTATAAAGAAAAAGGTTTAATTGACTCACAGTCACGCATGGCTGGGGAGGCCTCAGGAAACTTACAGTCATGGCGGAAGACAAAGGAAAAGCAAGTACCTTTTTCACAAGGTGGCGGGAAAGAGAGAGAGAGAAGGAGGAACTAACAACCACTTATAAAACCGTCAGATCTCATGAGAACTCACTCAGTATCACGAGAACAGCATGGGGAAACCGCCCCCATGATCCAGTCACCTCCCACCAGGTCC...	TCACTTTTCCAGTATTGGCATTGTATTACTGTGTTTTCACACTGCTATACAGAAATACTCAAGACTGGGTAATTTATAAAGAAAAAGGTTTAATTGACTCACAGTCACGCATGGCTGGGGAGGCCTCAGGAAACTTACAGTCATGGCGGAAGACAAAGGAAAAGCAAGTACCTTTTTCACAAGGTGGCGGGAAAGAGAGAGAGAGAAGGAGGAACTAACAACCACTTATAAAACCGTCAGATCTCATGAGAACTCACTCAGTATCACGAGAACAGCATGGGGAAACCGCCCCCATGATCCAGTCACCTCCCACCAGGTCC...
Task1_train_42535	A mutation on Chromosome 12 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	CATCCGCCAGTGCACGGGAACCTTTGGCTACGGCTACGAGTACATGGGCCTGAACGGCAGGCTGGTCATCACGCCCCTCACCGATCGGATTTACCTGACGCTCACCCAGGTGACTGCCAGCCTGGCACTTGTGGTTACCACTTACCTTGGGGCGGGGCATTTTCTCTAAGCTTGAGGTGTGATGACTGCAGTGATTGAAATAGCAGGGGAGATCATTGCTTTGAAATCTCGAAAAGCTTTTCCATTTGGGATGTGACCAGATTGTCACCATTTGGGATTGGCATGTAAGTGTGGCCGTGCTTAGCCACTGGTACACTGGT...	CATCCGCCAGTGCACGGGAACCTTTGGCTACGGCTACGAGTACATGGGCCTGAACGGCAGGCTGGTCATCACGCCCCTCACCGATCGGATTTACCTGACGCTCACCCAGGTGACTGCCAGCCTGGCACTTGTGGTTACCACTTACCTTGGGGCGGGGCATTTTCTCTAAGCTTGAGGTGTGATGACTGCAGTGATTGAAATAGCAGGGGAGATCATTGCTTTGAAATCTCGAAAAGCTTTTCCATTTGGGATGTGACCAGATTGTCACCATTTGGGATTGGCATGTAAGTGTGGCCGTGCTTAGCCACTGGTACACTGGT...
Task1_train_42536	This genomic variant is located on Chromosome 12. Can you determine its pathogenicity and name any linked disease?	Benign	ATCCACCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACCGCACCCGACCTATTTTGTGGCTTTTGGATATTGTGTCCTAGTTAAAAGGCCTGATCACACTGCAAGATTGTAAAATAATTTCCCCATGATTTCTTTTGGTACTCTTATGTTTTAATTTTTTATATTTAAATCTTTTATCTATTGAGGATTTTTTTCCTGGGGTTCTGTGTGAGTTTGGATCCAATTTGAGTTTTTCCAGATGAGTAAAATCTGGCTTTTCTCAGGTCATTTGGATGTTAAGCGCAATGAGCCGGCACTTACATCTTGAC...	ATCCACCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACCGCACCCGACCTATTTTGTGGCTTTTGGATATTGTGTCCTAGTTAAAAGGCCTGATCACACTGCAAGATTGTAAAATAATTTCCCCATGATTTCTTTTGGTACTCTTATGTTTTAATTTTTTATATTTAAATCTTTTATCTATTGAGGATTTTTTTCCTGGGGTTCTGTGTGAGTTTGGATCCAATTTGAGTTTTTCCAGATGAGTAAAATCTGGCTTTTCTCAGGTCATTTGGATGTTAAGCGCAATGAGCCGGCACTTACATCTTGAC...
Task1_train_42537	A genetic alteration is present on Chromosome 12. Is this variant benign or disease-causing, and if the latter, which condition is involved?	Benign	GGGAGGGGACACCTTAGCACAGGGGGTCTACGTGGGTGTCACCCTGGGGGGAGGCAATGGCCTGGGGGGCATCACCAGGACCACAGTTGGCTCGACTGCATGGAAGTGGCCGGGCAAGCTGCAAACCCAGCACGGAGCCCTTCTCCCTGGCCTCTGAGGAGGCTTGTGTGGCCTGGGGATGGGTAGATTGTTCTGGAAGGCCAGTCCTACCACCCTTAGCCCTTGGCTCACAAATTGGTGAGAAAAATTCATTTCCCAATGGCTGTTTCTTCCAGATGGGGATCCCAGGGCCTTCCCCCCGATGAGCTCTCCGTTCAGAA...	GGGAGGGGACACCTTAGCACAGGGGGTCTACGTGGGTGTCACCCTGGGGGGAGGCAATGGCCTGGGGGGCATCACCAGGACCACAGTTGGCTCGACTGCATGGAAGTGGCCGGGCAAGCTGCAAACCCAGCACGGAGCCCTTCTCCCTGGCCTCTGAGGAGGCTTGTGTGGCCTGGGGATGGGTAGATTGTTCTGGAAGGCCAGTCCTACCACCCTTAGCCCTTGGCTCACAAATTGGTGAGAAAAATTCATTTCCCAATGGCTGTTTCTTCCAGATGGGGATCCCAGGGCCTTCCCCCCGATGAGCTCTCCGTTCAGAA...
Task1_train_42538	A genomic change on Chromosome 12 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	CACTGCTGAGCCTGCCCGAGCGTCAGGGCACTGCAACGCTTCTAAACCTGCGCACTCCCTGGGCCCGCCCAGACTTCTGGGGTCACAGCCCCCAGGGGAGGGAAGCCAAGAGTCTATGCTGTACCCTGGGTCCCGAAACTGCTTGGAATTGGGCAGTTTTGGGTGCACTAATGTAAAACAATGATTTTCACCACTGGGAGGGGAGACGCCCCGACTGGAACCACCTGAGAGGCTTTTGAAACTGCCTCCCCTAAGACACAGCCCTTGCTGTGAGACCCTGCTGCTGCTGGGAGTACTACATCAGGTGGGTGGGTGGGTGG...	CACTGCTGAGCCTGCCCGAGCGTCAGGGCACTGCAACGCTTCTAAACCTGCGCACTCCCTGGGCCCGCCCAGACTTCTGGGGTCACAGCCCCCAGGGGAGGGAAGCCAAGAGTCTATGCTGTACCCTGGGTCCCGAAACTGCTTGGAATTGGGCAGTTTTGGGTGCACTAATGTAAAACAATGATTTTCACCACTGGGAGGGGAGACGCCCCGACTGGAACCACCTGAGAGGCTTTTGAAACTGCCTCCCCTAAGACACAGCCCTTGCTGTGAGACCCTGCTGCTGCTGGGAGTACTACATCAGGTGGGTGGGTGGGTGG...
Task1_train_42539	With a mutation on Chromosome 12, classify this variant as benign or pathogenic. Include the disease if it's pathogenic.	Benign	TCCTCAAACACCCATGCATGTTCTCTTTGTATGGAACATATTAAAAGTGTTACTTTAAGAAGACCTATTGATTTCATTTAGTTAATTTTAAAGTATCATAGCGTATAGAGTAAAAGAAATGAAAAGATTGCTAAAACATAGTCCTAAACCTTAAAAGATTTCAGAGTGAATATTTTGAGATTTATTTTCTTCTTTTATCTCCTCCTTATTCTATTTGTGGTGTATTTTGTCCCCTGTAGGCTATCAAAGACTGGAAATAAGGCACTAAGAAATGTACCTTTATCTGCTCCACCAGAATGAAGCAGGATATGTGTGTGGGT...	TCCTCAAACACCCATGCATGTTCTCTTTGTATGGAACATATTAAAAGTGTTACTTTAAGAAGACCTATTGATTTCATTTAGTTAATTTTAAAGTATCATAGCGTATAGAGTAAAAGAAATGAAAAGATTGCTAAAACATAGTCCTAAACCTTAAAAGATTTCAGAGTGAATATTTTGAGATTTATTTTCTTCTTTTATCTCCTCCTTATTCTATTTGTGGTGTATTTTGTCCCCTGTAGGCTATCAAAGACTGGAAATAAGGCACTAAGAAATGTACCTTTATCTGCTCCACCAGAATGAAGCAGGATATGTGTGTGGGT...