Split (2)

train · 48.9k rows

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.

ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_32600	A mutation on Chromosome 1 is under review. Please evaluate whether this mutation is benign or pathogenic and specify the disease if necessary.	Benign	TGGGCAGTCTGTCACAGAGTAGGGGGGCTGAGCTGAGTCTTGAAGGATGAGCAGGTGTTCAGTGGTGGAAAAGTGGGCAGGGGCACTCCTGGGTGAAGGAGCAGCATGGGCACACCTCCAGAGATGTGAATGAGCAGGGTCTGTTCAGGAGTACGGACTAGGCAAAAGGGAAAAGTGTGTGGAGGACGAGGAGGGAAGTAAGGCTGGAAGTAGATGCAGGCCAGATGGTGGGAAGCCCCACAGGGCCTGGGGCCTGGGAAACACTTGTCAGCACTTGAAGGAAGGTAATTAAATAAAAGACAGATTGTTGGAGCCAAAGA...	TGGGCAGTCTGTCACAGAGTAGGGGGGCTGAGCTGAGTCTTGAAGGATGAGCAGGTGTTCAGTGGTGGAAAAGTGGGCAGGGGCACTCCTGGGTGAAGGAGCAGCATGGGCACACCTCCAGAGATGTGAATGAGCAGGGTCTGTTCAGGAGTACGGACTAGGCAAAAGGGAAAAGTGTGTGGAGGACGAGGAGGGAAGTAAGGCTGGAAGTAGATGCAGGCCAGATGGTGGGAAGCCCCACAGGGCCTGGGGCCTGGGAAACACTTGTCAGCACTTGAAGGAAGGTAATTAAATAAAAGACAGATTGTTGGAGCCAAAGA...
Task1_train_32601	Chromosome 1 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	AGGTGGCACTAGAGTTGATCCAAAAGGAGATTTAAATAGGTAGTGCTGGCCAGGGCAAGGGCCTAAGGAAATGGTGTGGTGGTAGGACCACGGCTGGTCACCAGAGGCTGTGAGGCTGTCGGGGTGGCTACAAGGCAGAGCCCAGCTTGGAGATGATGCTGGGCAGGGAGGACAGGCCAGCCTTGACTGCCAGGATAAGGAGGTGATTTGATGTTGAGAGTAGGTGGGAGTCATTGAGTATTTTATTTTATTTTATTTTACTTTTTCCTTTACAGAGGTACTCAAGTTAAAGCCATTGAGTATTCTTTAGCCAAGGCCAT...	AGGTGGCACTAGAGTTGATCCAAAAGGAGATTTAAATAGGTAGTGCTGGCCAGGGCAAGGGCCTAAGGAAATGGTGTGGTGGTAGGACCACGGCTGGTCACCAGAGGCTGTGAGGCTGTCGGGGTGGCTACAAGGCAGAGCCCAGCTTGGAGATGATGCTGGGCAGGGAGGACAGGCCAGCCTTGACTGCCAGGATAAGGAGGTGATTTGATGTTGAGAGTAGGTGGGAGTCATTGAGTATTTTATTTTATTTTATTTTACTTTTTCCTTTACAGAGGTACTCAAGTTAAAGCCATTGAGTATTCTTTAGCCAAGGCCAT...
Task1_train_32602	Here’s a variant located on Chromosome 1. What is the predicted biological effect — harmless or disease-causing?	Benign	CCCCTCCAGGATTACTTACATATACACCATGCGGGGGAGCTCACCACCTCTCAGCCATCCTACTCCCTTATAGGCTGCCCTGACTGGGAGAAAACGTCTGTGTGCTGTGCAAGATCTGCCTCCTGGTCCTGCCCTCTGAGCCTGAAGCCCAGAGGCTTCCAAACTTCTACCCACCCTATCCTGATATTCCAGCAGGATGGAGGGCAGGACAGGGACTGGGAGTGTGTGAAGGGGGCTTGGTGGTGGAGGATAGGCTACGGGTCCTGGAGGGCAGCTTGGGGCATCCAGCCCAACTAACCCCTGCATCGCCTCCTACACAT...	CCCCTCCAGGATTACTTACATATACACCATGCGGGGGAGCTCACCACCTCTCAGCCATCCTACTCCCTTATAGGCTGCCCTGACTGGGAGAAAACGTCTGTGTGCTGTGCAAGATCTGCCTCCTGGTCCTGCCCTCTGAGCCTGAAGCCCAGAGGCTTCCAAACTTCTACCCACCCTATCCTGATATTCCAGCAGGATGGAGGGCAGGACAGGGACTGGGAGTGTGTGAAGGGGGCTTGGTGGTGGAGGATAGGCTACGGGTCCTGGAGGGCAGCTTGGGGCATCCAGCCCAACTAACCCCTGCATCGCCTCCTACACAT...
Task1_train_32603	Chromosome 1 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	ACCATGCGGGGGAGCTCACCACCTCTCAGCCATCCTACTCCCTTATAGGCTGCCCTGACTGGGAGAAAACGTCTGTGTGCTGTGCAAGATCTGCCTCCTGGTCCTGCCCTCTGAGCCTGAAGCCCAGAGGCTTCCAAACTTCTACCCACCCTATCCTGATATTCCAGCAGGATGGAGGGCAGGACAGGGACTGGGAGTGTGTGAAGGGGGCTTGGTGGTGGAGGATAGGCTACGGGTCCTGGAGGGCAGCTTGGGGCATCCAGCCCAACTAACCCCTGCATCGCCTCCTACACATTGCCTCCTATCCCTGGACTCCAGGA...	ACCATGCGGGGGAGCTCACCACCTCTCAGCCATCCTACTCCCTTATAGGCTGCCCTGACTGGGAGAAAACGTCTGTGTGCTGTGCAAGATCTGCCTCCTGGTCCTGCCCTCTGAGCCTGAAGCCCAGAGGCTTCCAAACTTCTACCCACCCTATCCTGATATTCCAGCAGGATGGAGGGCAGGACAGGGACTGGGAGTGTGTGAAGGGGGCTTGGTGGTGGAGGATAGGCTACGGGTCCTGGAGGGCAGCTTGGGGCATCCAGCCCAACTAACCCCTGCATCGCCTCCTACACATTGCCTCCTATCCCTGGACTCCAGGA...
Task1_train_32604	Given this context: Chromosome 1 — does this variant present pathogenic behavior, and if so, what disease does it relate to?	Benign	TATTATGCCTTCCCTAACCCAGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGTGAGTCTGAGGGTGGGCCCGGTTTATCCTGCTCAGCCCTTGGGAAGGGCGATGCCCATCCTGTCCTGAACCATCCTGGAAATCAGGTGAGGTGGCGGCTGCTATCC...	TATTATGCCTTCCCTAACCCAGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGTGAGTCTGAGGGTGGGCCCGGTTTATCCTGCTCAGCCCTTGGGAAGGGCGATGCCCATCCTGTCCTGAACCATCCTGGAAATCAGGTGAGGTGGCGGCTGCTATCC...
Task1_train_32605	This mutation occurs on Chromosome 1. Does this change lead to a known medical condition, or is it benign?	Benign	CCCGATGGGTGTATTAAGGGAGTCAGAAGGGCAGTGGGAGGCTTCCTGGAGGAGAACTGGGTGGGTGATCCTCAGTGTTGCCCCACCTGCCTCCCACCCCAGGGTCCGGGCTCCTGTCTAACCTCACTCCTCCATCCACCAGCCCCTGTAGCCTTCTAATTCTACTCCAGAAACATCCTTCCTTGCCCTTCCTCAGTATTCTTGCCTGGACTTTATGGTTTTCTGCTTCCCCTCCCAGCACACTGAAGCCACAGCCCAGCTCAGACCCTCCCACGCTCTTCATCACAGGTGGGACAGCATCCCAATGCCTCAGCTGGCAG...	CCCGATGGGTGTATTAAGGGAGTCAGAAGGGCAGTGGGAGGCTTCCTGGAGGAGAACTGGGTGGGTGATCCTCAGTGTTGCCCCACCTGCCTCCCACCCCAGGGTCCGGGCTCCTGTCTAACCTCACTCCTCCATCCACCAGCCCCTGTAGCCTTCTAATTCTACTCCAGAAACATCCTTCCTTGCCCTTCCTCAGTATTCTTGCCTGGACTTTATGGTTTTCTGCTTCCCCTCCCAGCACACTGAAGCCACAGCCCAGCTCAGACCCTCCCACGCTCTTCATCACAGGTGGGACAGCATCCCAATGCCTCAGCTGGCAG...
Task1_train_32606	This mutation occurs on Chromosome 1. Does this change lead to a known medical condition, or is it benign?	Benign	ACAGATAAGGACCACAGCTGTGTCCTAACGCAGTGCCTGAGCCACACTGGGCACATAGTATGTGTGCAGTAAGCATGGGCTGAATGAAGGAGCCTACCCCACAGTAGGGCAAGCTGCCTCAGAGCTGGACAATATGATTATCAGAAGGAGGTGGGCAGACATTAGATACTTATGTGGTAGACAGTTGCTTTGAGTTACTAGAAGCAGTTGAAATAAAGAAGAGTTGGCTACATGGAACATCACTAGGACCCAATGTCTTTGAGGGTTCCAGATGAGATTAAAGCAAAGCTGAGTCTTGAAAGCTGAGGAGAGGTGGCTGC...	ACAGATAAGGACCACAGCTGTGTCCTAACGCAGTGCCTGAGCCACACTGGGCACATAGTATGTGTGCAGTAAGCATGGGCTGAATGAAGGAGCCTACCCCACAGTAGGGCAAGCTGCCTCAGAGCTGGACAATATGATTATCAGAAGGAGGTGGGCAGACATTAGATACTTATGTGGTAGACAGTTGCTTTGAGTTACTAGAAGCAGTTGAAATAAAGAAGAGTTGGCTACATGGAACATCACTAGGACCCAATGTCTTTGAGGGTTCCAGATGAGATTAAAGCAAAGCTGAGTCTTGAAAGCTGAGGAGAGGTGGCTGC...
Task1_train_32607	This variant is located on Chromosome 1. Evaluate its biological effect and specify any disease association.	Benign	CATAATTCATTGATAAGTGAAAATGAGAATAAGAAACCCAAATCTCAAAATTATAGTCCAACACCAGCACCATATGCATATACTCAGACTCCATCCCATAAATCTGTACATATTCAACATGTAGAATACTATTATGCACACAATTTTATAGTTAATCTTTTTTTGCTTAGCCATACACATCCCAAATGCTATTTTATCTCAACAAATATTTACCATATATTCTGGGACAATATTGAAAATATAACAAGTATGATTATATAAAATTATTGTGTAATTTAAAATGTTCACATTAATTCATTTTATTCTCTAGATATACCAAA...	CATAATTCATTGATAAGTGAAAATGAGAATAAGAAACCCAAATCTCAAAATTATAGTCCAACACCAGCACCATATGCATATACTCAGACTCCATCCCATAAATCTGTACATATTCAACATGTAGAATACTATTATGCACACAATTTTATAGTTAATCTTTTTTTGCTTAGCCATACACATCCCAAATGCTATTTTATCTCAACAAATATTTACCATATATTCTGGGACAATATTGAAAATATAACAAGTATGATTATATAAAATTATTGTGTAATTTAAAATGTTCACATTAATTCATTTTATTCTCTAGATATACCAAA...
Task1_train_32608	A mutation is present on Chromosome 1. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.	Benign	TCCTAATGCTGGTGCAAACCTTCCTGAGGCTCAGCTTCTTCCATTTCATGTCTCAGTTCTCTCCAGACATCCTTGGCTTCACATTTATTTTACATCTGCCCACAACCCTTTTCAACCTTTATCTCACAGCTGTCATAATCACATGGATGTAGCAGCTCAATTAGAAAATTCACATGCCTGAAATATACCTCCTTTTCCTGCATTTGCCCATGATGTGGCTTCTTCTGGATAGTTCTTCCCCCAGGAAGCCACCTTTCTCCCTCCCAAATTGTCACCAGTCATCCCTAGGTCCGTGCAGCCTCTGATACACACACATACAC...	TCCTAATGCTGGTGCAAACCTTCCTGAGGCTCAGCTTCTTCCATTTCATGTCTCAGTTCTCTCCAGACATCCTTGGCTTCACATTTATTTTACATCTGCCCACAACCCTTTTCAACCTTTATCTCACAGCTGTCATAATCACATGGATGTAGCAGCTCAATTAGAAAATTCACATGCCTGAAATATACCTCCTTTTCCTGCATTTGCCCATGATGTGGCTTCTTCTGGATAGTTCTTCCCCCAGGAAGCCACCTTTCTCCCTCCCAAATTGTCACCAGTCATCCCTAGGTCCGTGCAGCCTCTGATACACACACATACAC...
Task1_train_32609	This variant lies on Chromosome 1. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	GGACACACCGCGCCTGCCAGCTGGCCCATCAGCACACAGGTTCTGTCTCTTCCTCTTGTCTCCCAGCCTTTCCCAGGCACAGTGAAAGTACCTGCCCTGACTCCTCAGGCAGAGAAGGTCCCTAGTAATCCTGCAGAAGCCAGAACACACTCAGCCTGGGGAATTCCCTTGCTCAGGGGCTGGGAGCCAAGATGTGAGGGGCCGGATTCTGTGCCTTGGTTTATCAATGTCCCCACATGGAGATAACTGAATGAGACCCTGTCCAAACAGCATTCAAGAGGAGCCTCCATGAACTGTGCCACTGGTGGGAGGGGTGCCCT...	GGACACACCGCGCCTGCCAGCTGGCCCATCAGCACACAGGTTCTGTCTCTTCCTCTTGTCTCCCAGCCTTTCCCAGGCACAGTGAAAGTACCTGCCCTGACTCCTCAGGCAGAGAAGGTCCCTAGTAATCCTGCAGAAGCCAGAACACACTCAGCCTGGGGAATTCCCTTGCTCAGGGGCTGGGAGCCAAGATGTGAGGGGCCGGATTCTGTGCCTTGGTTTATCAATGTCCCCACATGGAGATAACTGAATGAGACCCTGTCCAAACAGCATTCAAGAGGAGCCTCCATGAACTGTGCCACTGGTGGGAGGGGTGCCCT...
Task1_train_32610	This variant lies on Chromosome 1. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	ACAACAGTGTGTGTCATATCATACATTTTTCTGTCTTGCCCAATGACATTTTTACTTCATTATATAGTGTTCACATATTTACATCTATTTCCCCATTTGGCAAATTCTGTACATGCCTTGAGATCTTTATACCATAGTCCTGTAATCCACTTAGCACAATATTGGCCAAAAACATAAAAATGTGAACAGTACACTGTCTTGGAGAGAAAAGCCCAATAATTATCATATAACGCACAACATTTGAAGCCTCCTGGTATGTGAAATATAAAACACACTTGAAATAGCTATTGAGCTGGAGAGGAAAACTCCAGAATGGCTGC...	ACAACAGTGTGTGTCATATCATACATTTTTCTGTCTTGCCCAATGACATTTTTACTTCATTATATAGTGTTCACATATTTACATCTATTTCCCCATTTGGCAAATTCTGTACATGCCTTGAGATCTTTATACCATAGTCCTGTAATCCACTTAGCACAATATTGGCCAAAAACATAAAAATGTGAACAGTACACTGTCTTGGAGAGAAAAGCCCAATAATTATCATATAACGCACAACATTTGAAGCCTCCTGGTATGTGAAATATAAAACACACTTGAAATAGCTATTGAGCTGGAGAGGAAAACTCCAGAATGGCTGC...
Task1_train_32611	This variant lies on Chromosome 1. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	ATTAGAAAGTGGAGGCTACGGGGACTGGGATCCACTCCGCCAGAGCTGGCAGAGAATAATCCCGAGGAACCAGCTCCCTCCACACACACACACACACACATTCGCCCCCGCTGGGGAGTGAGGGAGTGTCTGTCTACACTGAGCAAATCCACTGTGAGTCCTCTGCCCGCCCAGCGGATCTTTACTCCCACTCAGACAGAGATGAGAGGTCGCCAAGGGAAGAAGATGGTGCTGGCCCAACCTCCCTGCACAGTCCACCTCGTTCTGCTCAGCTGGACTCTGAAGTGAGGTCGAGTCTCAAAGAGAGGCCTGGCTGAGGT...	ATTAGAAAGTGGAGGCTACGGGGACTGGGATCCACTCCGCCAGAGCTGGCAGAGAATAATCCCGAGGAACCAGCTCCCTCCACACACACACACACACACATTCGCCCCCGCTGGGGAGTGAGGGAGTGTCTGTCTACACTGAGCAAATCCACTGTGAGTCCTCTGCCCGCCCAGCGGATCTTTACTCCCACTCAGACAGAGATGAGAGGTCGCCAAGGGAAGAAGATGGTGCTGGCCCAACCTCCCTGCACAGTCCACCTCGTTCTGCTCAGCTGGACTCTGAAGTGAGGTCGAGTCTCAAAGAGAGGCCTGGCTGAGGT...
Task1_train_32612	A mutation is present on Chromosome 1. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.	Benign	AATGGGGGTCAATGGCTGGGAATTACCTCCTGTCCCCGACCAACCAGTCCAGGGAATCGCAAACAGCTTTCCGCCCCCAACCTGCAGGTGTTTGGAGCCTTTCCTCTACCCCCTCCTCCCCCCACCCGCCTTAAAAAACCCTATACATGACCAATCAGGAATAGCTATTTAGTCCAACAGCAACAACAACCCCTCCCGACAGGCTGTCTGGAACATTTTCGAACCCTCCAACTGGGATCGGTCTGGTTCAGTGTTTGTTTTCTAAGCAGGGAGGTGTCTACGCGGTTGCCTCCTCAGCCAGGTCTCCGGCTGCCGCTACA...	AATGGGGGTCAATGGCTGGGAATTACCTCCTGTCCCCGACCAACCAGTCCAGGGAATCGCAAACAGCTTTCCGCCCCCAACCTGCAGGTGTTTGGAGCCTTTCCTCTACCCCCTCCTCCCCCCACCCGCCTTAAAAAACCCTATACATGACCAATCAGGAATAGCTATTTAGTCCAACAGCAACAACAACCCCTCCCGACAGGCTGTCTGGAACATTTTCGAACCCTCCAACTGGGATCGGTCTGGTTCAGTGTTTGTTTTCTAAGCAGGGAGGTGTCTACGCGGTTGCCTCCTCAGCCAGGTCTCCGGCTGCCGCTACA...
Task1_train_32613	This genomic variant is located on Chromosome 1. Can you determine its pathogenicity and name any linked disease?	Benign	ACCTGTAGAATGATGTTCACTTAGGATTGCTTGAAATAACAAATAAGAGATTTGGCCTAAAGGTCCATTAATAGAGCACTGGGGTTCAATATATTCTAGTACAAGGGTACAAAAGAATATTATGCAGCTGTTTAAATACAAGAGAAAGAACTGTATATCCCTATAAGGAAAAGTATCCAAGATATTATAATATCATGTTTAAAACAAAAACAAAAAAACAGGCCAGGTGCAGTGGCTCACGGCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGAAGATTGCTTGAGTCTAAGAGTTTGTCTGAGACCAGACTGGGCA...	ACCTGTAGAATGATGTTCACTTAGGATTGCTTGAAATAACAAATAAGAGATTTGGCCTAAAGGTCCATTAATAGAGCACTGGGGTTCAATATATTCTAGTACAAGGGTACAAAAGAATATTATGCAGCTGTTTAAATACAAGAGAAAGAACTGTATATCCCTATAAGGAAAAGTATCCAAGATATTATAATATCATGTTTAAAACAAAAACAAAAAAACAGGCCAGGTGCAGTGGCTCACGGCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGAAGATTGCTTGAGTCTAAGAGTTTGTCTGAGACCAGACTGGGCA...
Task1_train_32614	This variant is present on Chromosome 1. Is the change likely to result in a pathogenic outcome?	Benign	GGAGGCTGCTGTTAGATGAAACTGCAAAGTGTTCTCAGTACCCTTTCCTAAATGGCCTAGAATATGGCTACACTTATACATCAGTTCTGAGGTAGGTGTTACTAGCCTCATTTTTACAAAGGCAGAAACAAAGCGCAAAGAACCTTGCCCAAGGTGACAGATAGGGTAAGTAGTGAAGGCAGGATTGGAACCCCAGGAGCCTGACTTAAGGTCGCTGCTCTTAACTACTATGCAGACCAGGAAACTGAGGCTCCGAAGCGGGGAAGTCACCTAATGAGGGTCACACAGCCTTGCTACAGCGGAGGCAGCTGGGATTCCGG...	GGAGGCTGCTGTTAGATGAAACTGCAAAGTGTTCTCAGTACCCTTTCCTAAATGGCCTAGAATATGGCTACACTTATACATCAGTTCTGAGGTAGGTGTTACTAGCCTCATTTTTACAAAGGCAGAAACAAAGCGCAAAGAACCTTGCCCAAGGTGACAGATAGGGTAAGTAGTGAAGGCAGGATTGGAACCCCAGGAGCCTGACTTAAGGTCGCTGCTCTTAACTACTATGCAGACCAGGAAACTGAGGCTCCGAAGCGGGGAAGTCACCTAATGAGGGTCACACAGCCTTGCTACAGCGGAGGCAGCTGGGATTCCGG...
Task1_train_32615	Chromosome 1 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	CTGTGTGTGATTGCATGTGTGAGAGTGTGTGTGTACTGTGCCTGTGTGGGCGTGAGTGCATGTGTGTCAGAGTGTGTGTGTGTGTATGTGTGAGAGAGTGTGTGTACTGTGCCTGTGTGGGCGTGAGTGCATGTGTGTGTCAGAGTGTGTGTAATTGCATGAGTGTGTGTGTACTGTGCCTGTGTGGGTGTGAGTGCATGTGTGTCAGAGTGTGTGTGTGTGTACTGTGCCTGTGTGTGTGATTGCATCTGTGTGTGCATGTGTGAGAGTGTGTGTGTACTGTGCCTGTGTGTGTGTGAGTGTACATGTGAGTGTGCATG...	CTGTGTGTGATTGCATGTGTGAGAGTGTGTGTGTACTGTGCCTGTGTGGGCGTGAGTGCATGTGTGTCAGAGTGTGTGTGTGTGTATGTGTGAGAGAGTGTGTGTACTGTGCCTGTGTGGGCGTGAGTGCATGTGTGTGTCAGAGTGTGTGTAATTGCATGAGTGTGTGTGTACTGTGCCTGTGTGGGTGTGAGTGCATGTGTGTCAGAGTGTGTGTGTGTGTACTGTGCCTGTGTGTGTGATTGCATCTGTGTGTGCATGTGTGAGAGTGTGTGTGTACTGTGCCTGTGTGTGTGTGAGTGTACATGTGAGTGTGCATG...
Task1_train_32616	A genomic change on Chromosome 1 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	AAAATACCTCATCATATAATCTACAGCCAGAGAGTAACTCAGCAATTGTGTAGTCCAGCATTTCTACAACCTAGGTATCCACATGTACCTTAGGATGACATTGGCAGGTAGTGTGAGGAGCTAGGGGAATGGGGGGTGGTGGCAAGAATAACAAATAGTGGTACATGCTAAATTTAGTTTAGAAAATTCTGGGTTAATTCGATAAATATTTAAGGAACATCAATTACATGCCAGGCTGTCTACTAGATGCAGAGTAAGACAGATTTATACCAGAATTTTCTTAAAGCCTCGAACAAGCTACTGTTCACAATGAGCACAGT...	AAAATACCTCATCATATAATCTACAGCCAGAGAGTAACTCAGCAATTGTGTAGTCCAGCATTTCTACAACCTAGGTATCCACATGTACCTTAGGATGACATTGGCAGGTAGTGTGAGGAGCTAGGGGAATGGGGGGTGGTGGCAAGAATAACAAATAGTGGTACATGCTAAATTTAGTTTAGAAAATTCTGGGTTAATTCGATAAATATTTAAGGAACATCAATTACATGCCAGGCTGTCTACTAGATGCAGAGTAAGACAGATTTATACCAGAATTTTCTTAAAGCCTCGAACAAGCTACTGTTCACAATGAGCACAGT...
Task1_train_32617	Given this context: Chromosome 1 — does this variant present pathogenic behavior, and if so, what disease does it relate to?	Benign	GGATCACTAAGGTCTCCCTGAGTGTCAGCACCATTTCATTGGTATATGACAATGCAACATGCAAGAAAAAAATGATTAAGGATCAAGATAATTTTATTTAGGCAGAGGACCTGAAAGAGACAATCCCCAAATTAACTTGTAAATGAGATTCTAAGAATTCTTTTGAGTTTTATAAAGCTTTAAACGTTTAAGAACTTTAACCAATCACGAATGACTTCTAAGAATGAACTGAGCATTTTCCTCTAGATGTGAGCTCCTCAGAGGCAGGGGTCATGCTTTAATCAGCCACTCATCCCAGCACTTCCCTCCTGTCAGGGGCC...	GGATCACTAAGGTCTCCCTGAGTGTCAGCACCATTTCATTGGTATATGACAATGCAACATGCAAGAAAAAAATGATTAAGGATCAAGATAATTTTATTTAGGCAGAGGACCTGAAAGAGACAATCCCCAAATTAACTTGTAAATGAGATTCTAAGAATTCTTTTGAGTTTTATAAAGCTTTAAACGTTTAAGAACTTTAACCAATCACGAATGACTTCTAAGAATGAACTGAGCATTTTCCTCTAGATGTGAGCTCCTCAGAGGCAGGGGTCATGCTTTAATCAGCCACTCATCCCAGCACTTCCCTCCTGTCAGGGGCC...
Task1_train_32618	Assess the clinical impact of this variant found on Chromosome 1. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	ACTAGCTGATAATAGCATTCTCTTTTCCTATTGAACCCAGATTTGGATTTAGAACGCTTCCTACCAAAATGCTGCAATTAACTGTCACCAACTAGGATAGAGGCTGTACTTGCAATCTCTTTGCTGGCCCTGACCTTTGACTTATAATAAATACTTAGCTGTTTTCTACCTATAAACAGAAAGAGGTCAGTTCACCAGGGTCAACTCACTTGGTTGGAGGATAGAATATTAAAAAGACAATCTTCAGAAATGATACAAGTTACAAATAGACATGGATTTGCACGTCTAAGGATCTACACCATGATATTTTTTGGCTTTTT...	ACTAGCTGATAATAGCATTCTCTTTTCCTATTGAACCCAGATTTGGATTTAGAACGCTTCCTACCAAAATGCTGCAATTAACTGTCACCAACTAGGATAGAGGCTGTACTTGCAATCTCTTTGCTGGCCCTGACCTTTGACTTATAATAAATACTTAGCTGTTTTCTACCTATAAACAGAAAGAGGTCAGTTCACCAGGGTCAACTCACTTGGTTGGAGGATAGAATATTAAAAAGACAATCTTCAGAAATGATACAAGTTACAAATAGACATGGATTTGCACGTCTAAGGATCTACACCATGATATTTTTTGGCTTTTT...
Task1_train_32619	This alteration occurs on Chromosome 1. Is it associated with a disease or is it a benign variant?	Benign	TTTGGGAGGCCAAGGCATGCACATTGCAAGATCAAGGGATCGAGACCATCCCGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTGGCTAGGTGTGGTGGTGCGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATTACGCCACTGCACTCCAGCCTGGCGACAGAGCAAGACTCTGTCTTTAAAAAAAAAAAAAAAAAAAAGGAAAGTTAAGTAAGGCTGGGCGCGATGGCTCACACCTGTAATCCCAACACTTTGAG...	TTTGGGAGGCCAAGGCATGCACATTGCAAGATCAAGGGATCGAGACCATCCCGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACACAAAAATTGGCTAGGTGTGGTGGTGCGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATTACGCCACTGCACTCCAGCCTGGCGACAGAGCAAGACTCTGTCTTTAAAAAAAAAAAAAAAAAAAAGGAAAGTTAAGTAAGGCTGGGCGCGATGGCTCACACCTGTAATCCCAACACTTTGAG...
Task1_train_32620	Chromosome 1 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	CCAGCCCATTTCATCCTATCTTTTTTTTTTTTTTTTTGAGATGGAGTCTCCTTCTGTCACCTAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGTGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACACCTGACCTTGTGATCCACCCGCCTTGGGCTCCTGAAGTGCTGGGGTTACAGGCATGAGCCACCGCACCCAGCCTAA...	CCAGCCCATTTCATCCTATCTTTTTTTTTTTTTTTTTGAGATGGAGTCTCCTTCTGTCACCTAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGTGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACACCTGACCTTGTGATCCACCCGCCTTGGGCTCCTGAAGTGCTGGGGTTACAGGCATGAGCCACCGCACCCAGCCTAA...
Task1_train_32621	Consider a variant on Chromosome 1. Determine its clinical classification and disease relevance.	Benign	GAAGCATAGCCCAGTTCTTCTTGCCTTCATGAATTCAAGCTCGCTTACCTCATCCTGGAAAATATCTGTCTCCTCTGAATTTATTTTTCTACTCCTACATAATAGTTTTCAGACACTGAGTCCTCACTTGATGTCTTTGATAAGTTCTTGGAAACTGTGACTTTAAGCAAATTGATACACTGTATGCCGGAGAACCTTAACTGTTGTTTATATCAATTAGCTTATAGTAAAATTGGCTTCTTTATACAGTGAGTTGTTTTGCTTATAATTGCAGTTTCCAAGAACCTATCAACAATGTTAAGTGAGGACTTACTGTACCT...	GAAGCATAGCCCAGTTCTTCTTGCCTTCATGAATTCAAGCTCGCTTACCTCATCCTGGAAAATATCTGTCTCCTCTGAATTTATTTTTCTACTCCTACATAATAGTTTTCAGACACTGAGTCCTCACTTGATGTCTTTGATAAGTTCTTGGAAACTGTGACTTTAAGCAAATTGATACACTGTATGCCGGAGAACCTTAACTGTTGTTTATATCAATTAGCTTATAGTAAAATTGGCTTCTTTATACAGTGAGTTGTTTTGCTTATAATTGCAGTTTCCAAGAACCTATCAACAATGTTAAGTGAGGACTTACTGTACCT...
Task1_train_32622	A mutation has occurred on Chromosome 1. What is the medical relevance of this mutation?	Benign	GCCTAAAAGCCTTAAGGCAGGAAGCAAAGGCTCACTGGAGAGGCCAGAGGCCATGGCAGAGGCAAATACAGAGCCCCACTTGGTGGAAGCCAGGATATGGCTCCCGGGGGGTAGTCTAGGAGAACAGAGAGGCCTTTGAGGCTGGCTGCCACGGAGGAGTTTCTTGTGCTCAGTTTCTGCTTGGGGCGGCTGCTGGGGGAGGGTCCTGGAAAGGGTGACTGCAGCCTTGCTGTGCAGGCCAGGCCACACACGTGTTACGTCTGGGCGCACAGGAGCATCAGAGGCACAGGGGCCCTCCTCCAGAACCCACCTGAGCTGCT...	GCCTAAAAGCCTTAAGGCAGGAAGCAAAGGCTCACTGGAGAGGCCAGAGGCCATGGCAGAGGCAAATACAGAGCCCCACTTGGTGGAAGCCAGGATATGGCTCCCGGGGGGTAGTCTAGGAGAACAGAGAGGCCTTTGAGGCTGGCTGCCACGGAGGAGTTTCTTGTGCTCAGTTTCTGCTTGGGGCGGCTGCTGGGGGAGGGTCCTGGAAAGGGTGACTGCAGCCTTGCTGTGCAGGCCAGGCCACACACGTGTTACGTCTGGGCGCACAGGAGCATCAGAGGCACAGGGGCCCTCCTCCAGAACCCACCTGAGCTGCT...
Task1_train_32623	Chromosome 1 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	AATTTAAAAAAAAAAGACTTCAGTAGGTTAAATAATTTTCATATATGCTAAAAAAATTTATTTTGTTTTACAGATAAGATTCAAAATTCATACCTGGATGTCTCTTAAGAATTTTTGCCAAATTTTCAATTATTTCCTTACAATTTAATTTCTAAAAAACAAATCAAATAAATAAGTTTGACTCAATTTCACCTTGTGCAAATTCTACTTTAATCTAAGCATTTAATAGTAGCATTTACAATTTCCAGCCATAAAGCTCTATAATAACCTTGCTACTCCAAGTAAGTGATTCATAGACCTACAGTATCAGCATAATCTGG...	AATTTAAAAAAAAAAGACTTCAGTAGGTTAAATAATTTTCATATATGCTAAAAAAATTTATTTTGTTTTACAGATAAGATTCAAAATTCATACCTGGATGTCTCTTAAGAATTTTTGCCAAATTTTCAATTATTTCCTTACAATTTAATTTCTAAAAAACAAATCAAATAAATAAGTTTGACTCAATTTCACCTTGTGCAAATTCTACTTTAATCTAAGCATTTAATAGTAGCATTTACAATTTCCAGCCATAAAGCTCTATAATAACCTTGCTACTCCAAGTAAGTGATTCATAGACCTACAGTATCAGCATAATCTGG...
Task1_train_32624	Chromosome 1 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	GGATAGAGTGTAGAAGGTTCATGAATTTACGTGGGAAAAATCACATCCTTGGTATGCATTACCTCTAACTGAAATTCAGTATTTTCTTTCATCATGCATATTGGTAAGAAAACCCACGATAGTATTAGTAGTGCTTGTGACTTTGTCACCAATAGAAATCACAGATATTTTCATATTGTATTACAGTAGAGACATATTGAAATACTAGTTATTTTCATTCACCACTTCAAAATTATAGTAATTAATAGACTCATCTCTAGATCTTATTGACACTTTTTAAAAAGTAGGACAAATCATGATTCAATATAATTGGTATCCTC...	GGATAGAGTGTAGAAGGTTCATGAATTTACGTGGGAAAAATCACATCCTTGGTATGCATTACCTCTAACTGAAATTCAGTATTTTCTTTCATCATGCATATTGGTAAGAAAACCCACGATAGTATTAGTAGTGCTTGTGACTTTGTCACCAATAGAAATCACAGATATTTTCATATTGTATTACAGTAGAGACATATTGAAATACTAGTTATTTTCATTCACCACTTCAAAATTATAGTAATTAATAGACTCATCTCTAGATCTTATTGACACTTTTTAAAAAGTAGGACAAATCATGATTCAATATAATTGGTATCCTC...
Task1_train_32625	A genomic variant on Chromosome 1 is under review. What is the biological outcome — benign or pathogenic?	Benign	TGCATTACCTCTAACTGAAATTCAGTATTTTCTTTCATCATGCATATTGGTAAGAAAACCCACGATAGTATTAGTAGTGCTTGTGACTTTGTCACCAATAGAAATCACAGATATTTTCATATTGTATTACAGTAGAGACATATTGAAATACTAGTTATTTTCATTCACCACTTCAAAATTATAGTAATTAATAGACTCATCTCTAGATCTTATTGACACTTTTTAAAAAGTAGGACAAATCATGATTCAATATAATTGGTATCCTCTGTAACCCTAAATAATTTTTTTTTTTAGTTAAAAACATTATTTGTGGCCTGGTG...	TGCATTACCTCTAACTGAAATTCAGTATTTTCTTTCATCATGCATATTGGTAAGAAAACCCACGATAGTATTAGTAGTGCTTGTGACTTTGTCACCAATAGAAATCACAGATATTTTCATATTGTATTACAGTAGAGACATATTGAAATACTAGTTATTTTCATTCACCACTTCAAAATTATAGTAATTAATAGACTCATCTCTAGATCTTATTGACACTTTTTAAAAAGTAGGACAAATCATGATTCAATATAATTGGTATCCTCTGTAACCCTAAATAATTTTTTTTTTTAGTTAAAAACATTATTTGTGGCCTGGTG...
Task1_train_32626	Here’s a variant located on Chromosome 1. What is the predicted biological effect — harmless or disease-causing?	Benign	TAGAAATCACAGATATTTTCATATTGTATTACAGTAGAGACATATTGAAATACTAGTTATTTTCATTCACCACTTCAAAATTATAGTAATTAATAGACTCATCTCTAGATCTTATTGACACTTTTTAAAAAGTAGGACAAATCATGATTCAATATAATTGGTATCCTCTGTAACCCTAAATAATTTTTTTTTTTAGTTAAAAACATTATTTGTGGCCTGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGGCAACATGGTGAAA...	TAGAAATCACAGATATTTTCATATTGTATTACAGTAGAGACATATTGAAATACTAGTTATTTTCATTCACCACTTCAAAATTATAGTAATTAATAGACTCATCTCTAGATCTTATTGACACTTTTTAAAAAGTAGGACAAATCATGATTCAATATAATTGGTATCCTCTGTAACCCTAAATAATTTTTTTTTTTAGTTAAAAACATTATTTGTGGCCTGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGGCAACATGGTGAAA...
Task1_train_32627	A variant on Chromosome 1 has been observed. Is this a neutral mutation, or does it result in a disease? If so, which one?	Benign	CACACACACACACACACACACACACAATTAGTCCTCATATTCTCCAATTCTGTATTTGCAAATTTCCCTACTTGCTAAAATTTACTTGTAACGTCAGCATCAATACTCAAGGCAATTCTGAGGTCATTTGTAAATGTGGGCACACACAGAGTAGCAAAAAATTTGATTTACACATGTATCCTAGGTGATATTGAATAAGGTATGCTCTGCCTTCTCTTTGCAGCTCTCATGGTACAAGCAAGTGTCTTTTTCTCAGTCTATTTAGTGCCATGGTTTTTGTATTTTTTTATTTTTAATGGGTGATTTCACTGTTTTGTTTT...	CACACACACACACACACACACACACAATTAGTCCTCATATTCTCCAATTCTGTATTTGCAAATTTCCCTACTTGCTAAAATTTACTTGTAACGTCAGCATCAATACTCAAGGCAATTCTGAGGTCATTTGTAAATGTGGGCACACACAGAGTAGCAAAAAATTTGATTTACACATGTATCCTAGGTGATATTGAATAAGGTATGCTCTGCCTTCTCTTTGCAGCTCTCATGGTACAAGCAAGTGTCTTTTTCTCAGTCTATTTAGTGCCATGGTTTTTGTATTTTTTTATTTTTAATGGGTGATTTCACTGTTTTGTTTT...
Task1_train_32628	Given this variant on Chromosome 1, classify it as benign or pathogenic. Include the disorder it may cause if applicable.	Benign	ACACACACACAATTAGTCCTCATATTCTCCAATTCTGTATTTGCAAATTTCCCTACTTGCTAAAATTTACTTGTAACGTCAGCATCAATACTCAAGGCAATTCTGAGGTCATTTGTAAATGTGGGCACACACAGAGTAGCAAAAAATTTGATTTACACATGTATCCTAGGTGATATTGAATAAGGTATGCTCTGCCTTCTCTTTGCAGCTCTCATGGTACAAGCAAGTGTCTTTTTCTCAGTCTATTTAGTGCCATGGTTTTTGTATTTTTTTATTTTTAATGGGTGATTTCACTGTTTTGTTTTGGTTTATTTTTATTT...	ACACACACACAATTAGTCCTCATATTCTCCAATTCTGTATTTGCAAATTTCCCTACTTGCTAAAATTTACTTGTAACGTCAGCATCAATACTCAAGGCAATTCTGAGGTCATTTGTAAATGTGGGCACACACAGAGTAGCAAAAAATTTGATTTACACATGTATCCTAGGTGATATTGAATAAGGTATGCTCTGCCTTCTCTTTGCAGCTCTCATGGTACAAGCAAGTGTCTTTTTCTCAGTCTATTTAGTGCCATGGTTTTTGTATTTTTTTATTTTTAATGGGTGATTTCACTGTTTTGTTTTGGTTTATTTTTATTT...
Task1_train_32629	Consider this mutation on Chromosome 1. Is this a benign change or a disease-causing variant?	Benign	ATATTCTCCAATTCTGTATTTGCAAATTTCCCTACTTGCTAAAATTTACTTGTAACGTCAGCATCAATACTCAAGGCAATTCTGAGGTCATTTGTAAATGTGGGCACACACAGAGTAGCAAAAAATTTGATTTACACATGTATCCTAGGTGATATTGAATAAGGTATGCTCTGCCTTCTCTTTGCAGCTCTCATGGTACAAGCAAGTGTCTTTTTCTCAGTCTATTTAGTGCCATGGTTTTTGTATTTTTTTATTTTTAATGGGTGATTTCACTGTTTTGTTTTGGTTTATTTTTATTTTCATTTTTTGAGATGGAGTCT...	ATATTCTCCAATTCTGTATTTGCAAATTTCCCTACTTGCTAAAATTTACTTGTAACGTCAGCATCAATACTCAAGGCAATTCTGAGGTCATTTGTAAATGTGGGCACACACAGAGTAGCAAAAAATTTGATTTACACATGTATCCTAGGTGATATTGAATAAGGTATGCTCTGCCTTCTCTTTGCAGCTCTCATGGTACAAGCAAGTGTCTTTTTCTCAGTCTATTTAGTGCCATGGTTTTTGTATTTTTTTATTTTTAATGGGTGATTTCACTGTTTTGTTTTGGTTTATTTTTATTTTCATTTTTTGAGATGGAGTCT...
Task1_train_32630	A variant was discovered on Chromosome 1. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	CCCACCACCACACCCAGATAATTTTTGTATTTTTAGTAGATACGAGGTTTCACTATGTTGGCCAGGCTGTTCTCGAAATCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTGCAAGCGTGAGCCACTGCACCTGGCCTAGTTTTGTTTTTGTTTTTGAGACAGAGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGCACAGTCTCAGTTTACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCGAAGTAGCTGGGATTACAGGTATGCATCACCACGCCCAGCTAA...	CCCACCACCACACCCAGATAATTTTTGTATTTTTAGTAGATACGAGGTTTCACTATGTTGGCCAGGCTGTTCTCGAAATCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTGCAAGCGTGAGCCACTGCACCTGGCCTAGTTTTGTTTTTGTTTTTGAGACAGAGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGCACAGTCTCAGTTTACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCGAAGTAGCTGGGATTACAGGTATGCATCACCACGCCCAGCTAA...
Task1_train_32631	A sequence alteration has been identified on Chromosome 1. Is it disease-inducing or harmless?	Benign	TAGGTGCACTCTGTGATGCTCCCACAATGACCACAATCACCTAATGATGCATTTCTCAGAATGTAGCCCCGTTGTTAAGCAACACATGACTCTATGAGAAATAAAGCCGCTAAGAACAGTGAAGAATGGTTTACCACCCAACCTCAAGCTCAAAGGCAGCAGGTAAAATGTAACAGTGCTCTTGTGCCATCAGCCCCAGTGGAAGGCAGAACCTGCAGCTTCTAATATGAACATCAAATGACCCCAACTCATTCCCTGTGAGGGCTCCGTGTGTGATCTCATCCCCATGCCTCCTCTGCACTGTCATCTTGGTTTCTGTC...	TAGGTGCACTCTGTGATGCTCCCACAATGACCACAATCACCTAATGATGCATTTCTCAGAATGTAGCCCCGTTGTTAAGCAACACATGACTCTATGAGAAATAAAGCCGCTAAGAACAGTGAAGAATGGTTTACCACCCAACCTCAAGCTCAAAGGCAGCAGGTAAAATGTAACAGTGCTCTTGTGCCATCAGCCCCAGTGGAAGGCAGAACCTGCAGCTTCTAATATGAACATCAAATGACCCCAACTCATTCCCTGTGAGGGCTCCGTGTGTGATCTCATCCCCATGCCTCCTCTGCACTGTCATCTTGGTTTCTGTC...
Task1_train_32632	Given a variant located on Chromosome 1, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	CGGAGCAGTAAAGTGGCTCATCCAGGCTTACACAGCAGTCAGAATTGGAACCCATGCCCTTCTGTCTCTAAAGCTCTCCATATGAGAAACACTCACTGCTGGCTGAGCTTCCCCGCTGTCCAGGGGTTTGAGATGTTCCTCACCAGGTGGACTTGAAACTCCTGGAGACCAGGGAGCTCCCCTGTTCTTCCCCACACACCTCCCACATGGCTGGGTACACAGAAGGGGCCTTGGGGGGCTTATCTTGCTCCATTCTTAGAAGAGCAAGGCTGGGTACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGC...	CGGAGCAGTAAAGTGGCTCATCCAGGCTTACACAGCAGTCAGAATTGGAACCCATGCCCTTCTGTCTCTAAAGCTCTCCATATGAGAAACACTCACTGCTGGCTGAGCTTCCCCGCTGTCCAGGGGTTTGAGATGTTCCTCACCAGGTGGACTTGAAACTCCTGGAGACCAGGGAGCTCCCCTGTTCTTCCCCACACACCTCCCACATGGCTGGGTACACAGAAGGGGCCTTGGGGGGCTTATCTTGCTCCATTCTTAGAAGAGCAAGGCTGGGTACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGC...
Task1_train_32633	A variant on Chromosome 1 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	ATTTAAAAATTTGGCTGGCACGGTTGTGACCCCCTATAGTCCCAGTTGCTTGAGAGGCTGAGGCTGGAGGATCACTTCAGCCCCGGAGCTCAAGGTTACAGTGAGCTATGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGGCCTTGTCTTAAAAAAAAAAAAAAAAAAAAGCCCAGCAAGATCTACAAGATCTAGACAAGGGAAGGAAAAGGAGCAGCAGCAGAGGATTCTGGAGTGAGCAGTGGTGTGGCAGGGGTGCAGACCATGCCCATGGAACAGACAATTAGTGGCAGGAAAAGCTAACGTTTACTG...	ATTTAAAAATTTGGCTGGCACGGTTGTGACCCCCTATAGTCCCAGTTGCTTGAGAGGCTGAGGCTGGAGGATCACTTCAGCCCCGGAGCTCAAGGTTACAGTGAGCTATGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGGCCTTGTCTTAAAAAAAAAAAAAAAAAAAAGCCCAGCAAGATCTACAAGATCTAGACAAGGGAAGGAAAAGGAGCAGCAGCAGAGGATTCTGGAGTGAGCAGTGGTGTGGCAGGGGTGCAGACCATGCCCATGGAACAGACAATTAGTGGCAGGAAAAGCTAACGTTTACTG...
Task1_train_32634	Mutation context: Chromosome 1. Determine if this variant is likely to be benign or pathogenic. Mention the disease if applicable.	Benign	GGTTGTGACCCCCTATAGTCCCAGTTGCTTGAGAGGCTGAGGCTGGAGGATCACTTCAGCCCCGGAGCTCAAGGTTACAGTGAGCTATGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGGCCTTGTCTTAAAAAAAAAAAAAAAAAAAAGCCCAGCAAGATCTACAAGATCTAGACAAGGGAAGGAAAAGGAGCAGCAGCAGAGGATTCTGGAGTGAGCAGTGGTGTGGCAGGGGTGCAGACCATGCCCATGGAACAGACAATTAGTGGCAGGAAAAGCTAACGTTTACTGAGCACTTACTATGTGCAGTAC...	GGTTGTGACCCCCTATAGTCCCAGTTGCTTGAGAGGCTGAGGCTGGAGGATCACTTCAGCCCCGGAGCTCAAGGTTACAGTGAGCTATGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGGCCTTGTCTTAAAAAAAAAAAAAAAAAAAAGCCCAGCAAGATCTACAAGATCTAGACAAGGGAAGGAAAAGGAGCAGCAGCAGAGGATTCTGGAGTGAGCAGTGGTGTGGCAGGGGTGCAGACCATGCCCATGGAACAGACAATTAGTGGCAGGAAAAGCTAACGTTTACTGAGCACTTACTATGTGCAGTAC...
Task1_train_32635	This sequence change occurs on Chromosome 1. What is the medical significance of this variant — is it benign or linked to a disease?	Benign	GTCAGGCAAGGACTCCAGGGCTGAAAGGGTCAGGGGTCAACTGAGACCTTGAAAGGCGTGGAGGGGCCTCTGCCAGGGGTCAGGAAATCCTATTTCTCCCGCTAGCTTATGGGACCACCTGTGGTGGGGCACGGCCCCTTCTGGTCCTTGGTTCTGTCAGCTGTGTAGGCAACATCTGAGGTGCTTCTAACTCTGTACCCTTGAGTTTGGATGGAAGGAGAGCAGCCTGGGCAAGGGTTTAGAGGCTCACCAGTTGAGCTGGCGCAGGGCCTGGGGAGCCCAGGTGGGTGAGGACCTGTGCCTTGACCCCCAGGTCTGTG...	GTCAGGCAAGGACTCCAGGGCTGAAAGGGTCAGGGGTCAACTGAGACCTTGAAAGGCGTGGAGGGGCCTCTGCCAGGGGTCAGGAAATCCTATTTCTCCCGCTAGCTTATGGGACCACCTGTGGTGGGGCACGGCCCCTTCTGGTCCTTGGTTCTGTCAGCTGTGTAGGCAACATCTGAGGTGCTTCTAACTCTGTACCCTTGAGTTTGGATGGAAGGAGAGCAGCCTGGGCAAGGGTTTAGAGGCTCACCAGTTGAGCTGGCGCAGGGCCTGGGGAGCCCAGGTGGGTGAGGACCTGTGCCTTGACCCCCAGGTCTGTG...
Task1_train_32636	Consider this mutation on Chromosome 1. Is this a benign change or a disease-causing variant?	Benign	AGGTGGTACCCAGCTCTGAGCTAAGAAGAGCCTCTGATGGGCAGAGCTGCCCCACTGTGGGTTGAGATGCTCGGGAAGTGGTGACCTCCCTGCTGCTGGAGGTGTGTAAGGATGCTCCTGCCAAGTCCACTAAAGAGCAGACTCCTGCCTTGTGCTGGGACAGACTCGATTGCTCAAGGGGTCTTAGAGATGTGACACCTAGAAGGGGCTGCTAAGCTTGTCTGCATGAAGGTGGGATGACCGATTGCATGACATCTGACCTCTCCCAGGTGAGGAGGCCTCAGGGAAGGAAGGATGCTCTCGTGGAGGCCTGCAGCCCC...	AGGTGGTACCCAGCTCTGAGCTAAGAAGAGCCTCTGATGGGCAGAGCTGCCCCACTGTGGGTTGAGATGCTCGGGAAGTGGTGACCTCCCTGCTGCTGGAGGTGTGTAAGGATGCTCCTGCCAAGTCCACTAAAGAGCAGACTCCTGCCTTGTGCTGGGACAGACTCGATTGCTCAAGGGGTCTTAGAGATGTGACACCTAGAAGGGGCTGCTAAGCTTGTCTGCATGAAGGTGGGATGACCGATTGCATGACATCTGACCTCTCCCAGGTGAGGAGGCCTCAGGGAAGGAAGGATGCTCTCGTGGAGGCCTGCAGCCCC...
Task1_train_32637	This alteration on Chromosome 1 may affect genome function. Does it lead to a disease or is it benign?	Benign	GCAAGTGGAGTGTTACCATATTTTATTCCTTTAAACCAAGAAAGGAAACAGAAGAGGAAGAAAAAGCAATTAATAAACATTAGGAAAATGCAAACCAAATCTGCAATGCTATACTACTTTACACCTACCAGAATATCTCCACGCCACAAGACATGTAACAAGTGCTGCTGAGGATGTGGAAAAATTGGAACCCTCACAGACAGCTCGTGGGAATGGTGCAGCCACTTTGGAAAACATCCTGGCAGTTCCTCAAAGGTTAAACAGAGACTTACCATGTGATAGTAGTTCCACTCCTAGCTATGTCCATACAAAAACATGTA...	GCAAGTGGAGTGTTACCATATTTTATTCCTTTAAACCAAGAAAGGAAACAGAAGAGGAAGAAAAAGCAATTAATAAACATTAGGAAAATGCAAACCAAATCTGCAATGCTATACTACTTTACACCTACCAGAATATCTCCACGCCACAAGACATGTAACAAGTGCTGCTGAGGATGTGGAAAAATTGGAACCCTCACAGACAGCTCGTGGGAATGGTGCAGCCACTTTGGAAAACATCCTGGCAGTTCCTCAAAGGTTAAACAGAGACTTACCATGTGATAGTAGTTCCACTCCTAGCTATGTCCATACAAAAACATGTA...
Task1_train_32638	A mutation found on Chromosome 1 may be clinically relevant. Is it pathogenic or benign, and if the former, which disease is implicated?	Benign	CTTGCCTCCTAAGCAGGGGTGGGGAAATGCATGTGTCTTTGTCCTCATTTAAGGTCACTTTCAGCTGTGACGCATTAATTCTTTTTTCTTTCTTTTTTTTTTTTTTTTTTGGAGACAAGAGTTTCCCTCCGTCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCAACCTCCACCCCCAGGTTCAAGTGATTCTCCTGCCTCTGCCTCCCAAGTAGCTGGGATAATAGGCACCCGCCACTACACCTGGCTAGTTTTTGCATTTTTAGTAAAGAAGGGGTTTTGCCATTTTGGCCAGGCTGGTCTTGAACTCCTGA...	CTTGCCTCCTAAGCAGGGGTGGGGAAATGCATGTGTCTTTGTCCTCATTTAAGGTCACTTTCAGCTGTGACGCATTAATTCTTTTTTCTTTCTTTTTTTTTTTTTTTTTTGGAGACAAGAGTTTCCCTCCGTCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCAACCTCCACCCCCAGGTTCAAGTGATTCTCCTGCCTCTGCCTCCCAAGTAGCTGGGATAATAGGCACCCGCCACTACACCTGGCTAGTTTTTGCATTTTTAGTAAAGAAGGGGTTTTGCCATTTTGGCCAGGCTGGTCTTGAACTCCTGA...
Task1_train_32639	This sequence variant lies on Chromosome 1. Is it clinically significant, and what condition might it cause if any?	Benign	TGCATGTCATGAGGAGATTGCTGGATTATGCAAAACACACTGCCCAAGCTCCAGAATATAGTTATTTTCTTAGAGTTTAGGAGGCCAAGAGTGACACAGAGGAAGGTCCTAGGTACAGGATGCTAGAACTCCAGAATGTCTGACTGAAAATTCAAAGGGTATCAAGCTGGTGAGACATCCAACTTCATTGAGTTGGGGGCATCTGGCAGGTAGGGATGGGAAGGCATTTGCTTAAGTGTGTCAAGTTCCAGGTATGATGAGATTAGATGCAGCTCCTCTGCTCCTACTTAAGTCAAACACTTCCATGTTGCACCTTGTCC...	TGCATGTCATGAGGAGATTGCTGGATTATGCAAAACACACTGCCCAAGCTCCAGAATATAGTTATTTTCTTAGAGTTTAGGAGGCCAAGAGTGACACAGAGGAAGGTCCTAGGTACAGGATGCTAGAACTCCAGAATGTCTGACTGAAAATTCAAAGGGTATCAAGCTGGTGAGACATCCAACTTCATTGAGTTGGGGGCATCTGGCAGGTAGGGATGGGAAGGCATTTGCTTAAGTGTGTCAAGTTCCAGGTATGATGAGATTAGATGCAGCTCCTCTGCTCCTACTTAAGTCAAACACTTCCATGTTGCACCTTGTCC...