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The dataset generation failed
Error code: DatasetGenerationError
Exception: TypeError
Message: Couldn't cast array of type
list<item: list<item: float>>
to
List(Value('float32'), length=512)
Traceback: Traceback (most recent call last):
File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 1869, in _prepare_split_single
for key, table in generator:
^^^^^^^^^
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 609, in wrapped
for item in generator(*args, **kwargs):
^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.12/site-packages/datasets/packaged_modules/hdf5/hdf5.py", line 91, in _generate_tables
yield Key(file_idx, batch_idx), cast_table_to_features(pa_table, self.info.features)
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.12/site-packages/datasets/table.py", line 2197, in cast_table_to_features
arrays = [cast_array_to_feature(table[name], feature) for name, feature in features.items()]
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.12/site-packages/datasets/table.py", line 1795, in wrapper
return pa.chunked_array([func(chunk, *args, **kwargs) for chunk in array.chunks])
^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.12/site-packages/datasets/table.py", line 2092, in cast_array_to_feature
raise TypeError(f"Couldn't cast array of type\n{_short_str(array.type)}\nto\n{_short_str(feature)}")
TypeError: Couldn't cast array of type
list<item: list<item: float>>
to
List(Value('float32'), length=512)
The above exception was the direct cause of the following exception:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1342, in compute_config_parquet_and_info_response
parquet_operations, partial, estimated_dataset_info = stream_convert_to_parquet(
^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 907, in stream_convert_to_parquet
builder._prepare_split(split_generator=splits_generators[split], file_format="parquet")
File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 1736, in _prepare_split
for job_id, done, content in self._prepare_split_single(
^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.12/site-packages/datasets/builder.py", line 1919, in _prepare_split_single
raise DatasetGenerationError("An error occurred while generating the dataset") from e
datasets.exceptions.DatasetGenerationError: An error occurred while generating the datasetNeed help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
embeddings
list | gene_names
string |
|---|---|
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] |
OR4F5
|
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SAMD11
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PLEKHN1
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PERM1
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HES4
|
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C1orf159
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TTLL10
|
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B3GALT6
|
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C1QTNF12
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UBE2J2
|
End of preview.
YAML Metadata
Warning:
empty or missing yaml metadata in repo card
(https://huggingface.co/docs/hub/datasets-cards)
CDT2-data
Data files for Central Dogma Transformer II (CDT-II).
Files
| File | Description | Size |
|---|---|---|
morris_celllevel_effects_2361.h5 |
Cell-level perturbation effects (TSS, 2,361 genes) | 41 MB |
morris_snp_celllevel_effects_2361.h5 |
Cell-level perturbation effects (SNP, 2,361 genes) | 34 MB |
k562_gene_embeddings_aligned.h5 |
Gene embeddings from scGPT (2,360 genes) | 4.4 MB |
cdt_morris_celllevel_best.pt |
Trained CDT-II model weights | 80 MB |
Enformer Embeddings (Not Included)
The Enformer embeddings must be generated using the notebooks in the CDT2 repository:
morris_28genes_enformer.h5- Generate withnotebooks/embeddings/Morris_28genes_Enformer.ipynbmorris_snp_enformer.h5- Generate withnotebooks/embeddings/Morris_SNP_Enformer.ipynb
These notebooks run Enformer inference on Google Colab and save the embeddings to Google Drive.
Usage
from huggingface_hub import hf_hub_download
# Download cell-level effects
effects_path = hf_hub_download(
repo_id="nobusama17/CDT2-data",
filename="morris_celllevel_effects_2361.h5",
repo_type="dataset"
)
# Download model weights
model_path = hf_hub_download(
repo_id="nobusama17/CDT2-data",
filename="cdt_morris_celllevel_best.pt",
repo_type="dataset"
)
Data Source
- Morris STING-seq v2 dataset (60,505 K562 cells, 447 perturbation loci)
- Reference: Morris et al. Science 2023
Citation
@article{ota2025cdtii,
title={Central Dogma Transformer II: An AI Microscope for Understanding Cellular Regulatory Mechanisms},
author={Ota, Nobuyuki},
journal={bioRxiv},
year={2025}
}
License
MIT License
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