| Type,OMIM (see references at OMIM link),Gene,Locus,Inheritance,Remarks |
| ALS1,105400,SOD1,21q22.1,"autosomal dominant (?), autosomal recessive (?)",The most common form of familial ALS |
| ALS2,205100,ALS2,2q33.1,autosomal recessive (?),Juvenile-onset |
| ALS3,606640,Unknown,18q21,Unknown,nan |
| ALS4,602433,SETX,9q34.13,autosomal dominant (?),nan |
| ALS5,602099,SPG11,15q21.1,autosomal recessive (?),[MISSING] |
| ALS6,608030,FUS,16p11.2,Unknown,nan |
| ALS7,608031,Unknown,20p13,Unknown,nan |
| ALS8,608627,VAPB,20q13.3,autosomal dominant (?),nan |
| ALS9,611895,ANG,14q11.2,Unknown,nan |
| ALS10,612069,TARDBP,1p36.2,autosomal dominant (?),ALS with or without frontotemporal dementia |
| ALS11,612577,FIG4,6q21,Unknown,nan |
| ALS12,613435,OPTN,10p13,Unknown,nan |
| ALS13,183090,ATXN2,12q24.12,autosomal dominant (?),Spinocerebellar ataxia 2 |
| ALS14,613954,VCP,9p13.3,Unknown,Recent new study shows strong link in ALS mechanism |
| ALS15,300857,UBQLN2,Xp11.21,X-linked dominant (?),Described in one family |
| ALS16,614373,SIGMAR1,9p13.3,autosomal recessive (?),"Juvenile onset, very rare, described only in one family" |
| ALS17,614696,CHMP2B,3p11.2,autosomal dominant (?),"Very rare, reported only in a handful of people" |
| ALS18,614808,PFN1,17p13.2,Unknown,"Very rare, described only in a handful of Chinese families" |
| ALS19,615515,ERBB4,2q34,autosomal dominant (?),"Very rare, as of late 2013 described only in four people" |
| ALS20,615426,HNRNPA1,12q13.13,Unknown,"Very rare, as of late 2013 described only in two people" |
| ALS21,606070,MATR3,5q31.2,autosomal dominant (?),"Very rare. Formerly known as ""distal myopathy type 2"" (MPD2) and ""vocal cord and pharyngeal dysfunction with distal myopathy"" (VCPDM)" |
| ALS22,616208,TUBA4A,2q35,autosomal dominant (?),"""Amyotrophic lateral sclerosis 22 with or without frontotemporal dementia""" |
| FTDALS1,105550,C9orf72,9p21.2,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 1"". Accounts for around 6% of ALS cases among white Europeans" |
| FTDALS2,615911,CHCHD10,22q11.23,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 2""" |
| FTDALS3,616437,SQSTM1,5q35.3,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 3""" |
| FTDALS4,616439,TBK1,12q14.2,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 4""" |
| IBMPFD2,615422,HNRNPA2B1,7p15.2,autosomal dominant (?),"Proposed names: Inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia 2 (IBMPFD2); multisystem proteinopathy 2 (MSP2). Very rare, as of late 2013 described only in two people" |
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