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51c7367 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 | Type,OMIM (see references at OMIM link),Gene,Locus,Inheritance,Remarks
ALS1,105400,SOD1,21q22.1,"autosomal dominant (?), autosomal recessive (?)",The most common form of familial ALS
ALS2,205100,ALS2,2q33.1,autosomal recessive (?),Juvenile-onset
ALS3,606640,Unknown,18q21,Unknown,nan
ALS4,602433,SETX,9q34.13,autosomal dominant (?),nan
ALS5,602099,SPG11,15q21.1,autosomal recessive (?),[MISSING]
ALS6,608030,FUS,16p11.2,Unknown,nan
ALS7,608031,Unknown,20p13,Unknown,nan
ALS8,608627,VAPB,20q13.3,autosomal dominant (?),nan
ALS9,611895,ANG,14q11.2,Unknown,nan
ALS10,612069,TARDBP,1p36.2,autosomal dominant (?),ALS with or without frontotemporal dementia
ALS11,612577,FIG4,6q21,Unknown,nan
ALS12,613435,OPTN,10p13,Unknown,nan
ALS13,183090,ATXN2,12q24.12,autosomal dominant (?),Spinocerebellar ataxia 2
ALS14,613954,VCP,9p13.3,Unknown,Recent new study shows strong link in ALS mechanism
ALS15,300857,UBQLN2,Xp11.21,X-linked dominant (?),Described in one family
ALS16,614373,SIGMAR1,9p13.3,autosomal recessive (?),"Juvenile onset, very rare, described only in one family"
ALS17,614696,CHMP2B,3p11.2,autosomal dominant (?),"Very rare, reported only in a handful of people"
ALS18,614808,PFN1,17p13.2,Unknown,"Very rare, described only in a handful of Chinese families"
ALS19,615515,ERBB4,2q34,autosomal dominant (?),"Very rare, as of late 2013 described only in four people"
ALS20,615426,HNRNPA1,12q13.13,Unknown,"Very rare, as of late 2013 described only in two people"
ALS21,606070,MATR3,5q31.2,autosomal dominant (?),"Very rare. Formerly known as ""distal myopathy type 2"" (MPD2) and ""vocal cord and pharyngeal dysfunction with distal myopathy"" (VCPDM)"
ALS22,616208,TUBA4A,2q35,autosomal dominant (?),"""Amyotrophic lateral sclerosis 22 with or without frontotemporal dementia"""
FTDALS1,105550,C9orf72,9p21.2,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 1"". Accounts for around 6% of ALS cases among white Europeans"
FTDALS2,615911,CHCHD10,22q11.23,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 2"""
FTDALS3,616437,SQSTM1,5q35.3,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 3"""
FTDALS4,616439,TBK1,12q14.2,autosomal dominant (?),"""Frontotemporal dementia and/or amyotrophic lateral sclerosis type 4"""
IBMPFD2,615422,HNRNPA2B1,7p15.2,autosomal dominant (?),"Proposed names: Inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia 2 (IBMPFD2); multisystem proteinopathy 2 (MSP2). Very rare, as of late 2013 described only in two people"
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