MedConclusion: A Benchmark for Biomedical Conclusion Generation from Structured Abstracts
Paper • 2604.06505 • Published • 2
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10,677,821 | Controlled trials of CQI and academic detailing to implement a clinical practice guideline for depression. | The Joint Commission journal on quality improvement | Jt Comm J Qual Improv | 26 | 1 | 10.1016/s1070-3241(00)26004-5 | eng | 2,000 | 1 | null | null | null | null | [BACKGROUND] The release of the Agency for Health Care Policy and Research (AHCPR)'s Guideline for the Detection and Treatment of Depression in Primary Care created an opportunity to evaluate under naturalistic conditions the effectiveness of two clinical practice guideline implementation methods: continuous quality im... | null | null | null | null | null | null |
10,678,297 | Quantification of human H1 histamine receptor mRNA from peripheral blood. | Pharmacotherapy | Pharmacotherapy | 20 | 2 | 10.1592/phco.20.3.191.34785 | eng | 2,000 | 2 | null | null | null | null | [STUDY OBJECTIVE] To develop a reverse transcription (RT)-polymerase chain reaction (PCR) technique to detect and quantify human histamine1 (H1) receptor mRNA in peripheral blood. [METHODS] Primer pairs were based on the human H1 receptor nucleotide sequence. A competitive reference standard (CRS) was developed that us... | null | 0.583 | 130 | Pharmacology | Medicine | 2,000 |
10,678,296 | Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity. | Pharmacotherapy | Pharmacotherapy | 20 | 2 | 10.1592/phco.20.3.182.34775 | eng | 2,000 | 2 | null | null | null | null | [STUDY OBJECTIVE] To evaluate the metabolism of antipyrine, a general metabolic probe, caffeine, a probe for cytochrome P450 (CYP) 1A2 and N-acetyltransferase activity, and dextromethorphan, a specific probe for CYP2D6 activity in patients with type 1 or 2 diabetes mellitus. [DESIGN] Prospective, controlled study. [SET... | null | 0.583 | 130 | Pharmacology | Medicine | 2,000 |
10,700,499 | Decreased severity of brain infarct can in part explain the decreasing case fatality rate of stroke. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.651 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] Case fatality rates for stroke has declined in most Western industrialized countries during recent decades. One possible explanation for this is a decrease in the severity of stroke symptoms. We therefore sought evidence for a change in stroke severity and its relationship with case fatality ra... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,497 | Functional and neuroanatomic correlations in poststroke depression: the Sunnybrook Stroke Study. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.637 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] The purpose of our study was to determine the functional and neuroanatomic correlates of poststroke depressive symptoms. [METHODS] Patients with consecutive admissions to a regional stroke center for new-onset unilateral hemispheric stroke who met World Health Organization and National Institut... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,495 | Low risk of ischemic stroke in patients with reduced internal carotid artery lumen diameter distal to severe symptomatic carotid stenosis: cerebral protection due to low poststenotic flow? On behalf of the European Carotid Surgery Trialists' Collaborative Group. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.622 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] Patients with recently symptomatic severe carotid stenosis have a high risk of ischemic stroke on medical treatment. The main mechanism of stroke appears to be plaque surface thrombus formation and distal embolism. It is unclear to what extent reduction in blood flow across the stenosis, and th... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,494 | Interrelation between plaque surface morphology and degree of stenosis on carotid angiograms and the risk of ischemic stroke in patients with symptomatic carotid stenosis. On behalf of the European Carotid Surgery Trialists' Collaborative Group. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.615 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] The risk of ischemic stroke distal to an atherothrombotic carotid stenosis increases with the degree of stenosis. The main mechanism of stroke is thought to be embolism from fissured or ruptured plaque, but there are few published data on the relationship between plaque morphology and severity ... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,493 | High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial doppler monitoring. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.610 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] Clot dissolution with tissue plasminogen activator (tPA) can lead to early clinical recovery after stroke. Transcranial Doppler (TCD) with low MHz frequency can determine arterial occlusion and monitor recanalization and may potentiate thrombolysis. [METHODS] Stroke patients receiving intraveno... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,492 | Abciximab in acute ischemic stroke. A randomized, double-blind, placebo-controlled, dose-escalation study. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.601 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] Abciximab is a potent parenterally administered platelet glycoprotein IIb/IIIa antagonist. Because this agent has been shown to improve outcomes in coronary artery disease, there is interest to evaluate whether it could improve cerebral perfusion and outcomes after ischemic stroke. This study w... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,489 | Management patterns and costs of acute ischemic stroke : an international study. For the Stroke Economic Analysis Group. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.582 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] [corrected] With the ever-increasing pressure on healthcare budgets, we witness a growing demand for evidence of the economic implications of care across many therapeutic areas. Stroke is no exception. [METHODS] Detailed information on healthcare use was collected in conjunction with two 12-wee... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,488 | Sex differences in the relationship of risk factors to subclinical carotid atherosclerosis measured 15 years later : the Tromsø study. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.574 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] Ultrasound measurement of carotid artery intima-media thickness (IMT) is regarded as a valid index of atherosclerosis. Determinants of IMT in cross-sectional studies have been established, but the long-term relationship between cardiovascular risk factors and subclinical atherosclerosis has not... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,487 | Effects of stress reduction on carotid atherosclerosis in hypertensive African Americans. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.568 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] African Americans suffer disproportionately higher cardiovascular disease mortality rates than do whites. Psychosocial stress influences the development and progression of atherosclerosis. Carotid intima-media thickness (IMT) is a valid surrogate measure for coronary atherosclerosis, is a predi... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,486 | Racial variation in initial stroke severity. | Stroke | Stroke | 31 | 3 | 10.1161/01.str.31.3.563 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND AND PURPOSE] Blacks experience greater morbidity and mortality from stroke than do whites. The degree to which this is due to the severity of the initial stroke is not known. The objective of this study is to determine whether there is a racial difference in initial stroke severity. [METHODS] A secondary an... | null | 3.617 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,000 |
10,700,435 | Importance of synovial fluid aspiration when injecting intra-articular corticosteroids. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.233 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] The aim of this prospective study was to find if a complete synovial fluid aspiration before injecting intra-articular corticosteroids influences the treatment result. [METHODS] The study was performed in 147 patients with rheumatoid arthritis (RA). One hundred and ninety one knees with synovitis were rando... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,433 | Diastolic function abnormalities in rheumatoid arthritis. Evaluation By echo Doppler transmitral flow and pulmonary venous flow: relation with duration of disease. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.227 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] The aim of this study was to evaluate left ventricular filling in patients with rheumatoid arthritis (RA), analysing transmitral flow and pulmonary venous flow, with special regard to age and disease duration. [METHODS] 32 patients affected by RA according to ARA criteria were selected, without evidence of ... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,432 | Predictors of functional status in patients with early rheumatoid arthritis. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.223 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] To find disease parameters that can predict the functional capacity of patients with early rheumatoid arthritis (RA) at the first visit to the rheumatologist and one year after entry. [METHODS] Patients referred to the outpatients clinic between 1995 and 1996, with a symptom duration of less than three year... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,431 | Anaemia in systemic lupus erythematosus: aetiological profile and the role of erythropoietin. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.217 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] To study the prevalence of different causes of anaemia in patients with systemic lupus erythematosus (SLE) and their associations with immunological and clinical parameters and to evaluate the contribution of erythropoietin (Epo) and anti-erythropoietin (anti-Epo) autoantibodies to the development of SLE an... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,430 | Subclinical gut inflammation in spondyloarthropathy patients is associated with upregulation of the E-cadherin/catenin complex. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.211 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] Previously an upregulation of E-cadherin and its associated molecules alpha-catenin, beta-catenin and plakoglobin has been demonstrated in clinically overt inflammatory bowel disease (IBD). The aim of this study was to investigate the expression of the E-cadherin/catenin complex in subclinically inflamed bo... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,429 | Prevalence of Raynaud's phenomenon in a healthy Greek population. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.206 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] Raynaud's phenomenon (RP) is comprised of repeated episodes of colour changes of the skin of digits on cold exposure or emotional stress. The prevalence of RP in the general population is variable fluctuating between 4%-15%, among surveys. The aim of this study was to estimate the prevalence of RP in a heal... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,428 | Blockade of endogenous interleukin 12 results in suppression of murine streptococcal cell wall arthritis by enhancement of interleukin 10 and interleukin 1Ra. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.196 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] The goal of this study was to investigate the role of endogenous interleukin 12 (IL12) in acute murine streptococcal cell wall (SCW) arthritis. [METHODS] C57black/6 mice were injected intraperitoneally with rat anti-murine IL12 (C17.8), shortly before induction of arthritis by intra-articular injection of 2... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,427 | Increased expression of CD40 ligand (CD154) on CD4+ T cells as a marker of disease activity in rheumatoid arthritis. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.190 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] The interaction between the activation induced surface glycoprotein CD40L (ligand) (CD154) on CD4+ T cells and its receptor CD40, which is expressed on various cell types, plays a crucial part in numerous cell mediated and humoral immune reactions that may be of pathogenetic importance in rheumatoid arthri... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,426 | Mast cells, extracellular matrix components, TGFbeta isoforms and TGFbeta receptor expression in labial salivary glands in systemic sclerosis. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.183 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] To determine whether there was altered elaboration of non-collagenous extracellular matrix proteins or expression of TGFbeta isoforms and their receptors in salivary glands of patients with systemic sclerosis (SSc) and Raynaud's phenomenon (RP). Because of the possible role of mast cells in the early stages... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,425 | Sonography for hip joint effusion in adults with hip pain. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.178 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] To study the prevalence of ultrasonic hip joint effusion and its relation with clinical, radiological and laboratory (ESR) findings in adults with hip pain. [METHODS] Patients (n = 224) aged 50 years or older with hip pain, referred by the general practitioner for radiological investigation, underwent a sta... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,700,424 | Immunogenetic differences between patients with familial and non-familial rheumatoid arthritis. | Annals of the rheumatic diseases | Ann Rheum Dis | 59 | 3 | 10.1136/ard.59.3.173 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] To search for possible immunogenetic differencies between the patients with familial and non-familial rheumatoid arthritis (RA). [METHODS] The study compared 129 familial RA patients with 217 non-familial patients for the frequencies of HLA-DR antigens including DR4 subtypes, DR4-DQB1*0301 and DR4-DQB1*0302... | null | 0.932 | 300 | Biochemistry, Genetics and Molecular Biology; Rheumatology; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,000 |
10,699,908 | Alternating drug pairs with or without periodic reinduction in children with acute lymphoblastic leukemia in second bone marrow remission: a Pediatric Oncology Group Study. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1166::aid-cncr29>3.0.co;2-w | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Children with acute lymphoblastic leukemia (ALL) who experience hematologic recurrence while receiving chemotherapy or within 6 months after its cessation have a low cure rate. In this study (Pediatric Oncology Group Protocol 8303) two methods were examined for improving the outcome in these children. [MET... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,907 | Phase II evaluation of cisplatin and etoposide followed by mitotane at disease progression in patients with locally advanced or metastatic adrenocortical carcinoma: a Southwest Oncology Group Study. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] A previous Southwest Oncology Group study demonstrated a 30% response rate with the combination of cisplatin and mitotane in the treatment of patients with metastatic adrenocortical carcinoma. Several case reports suggested that the combination of etoposide and cisplatin may be an active regimen in this di... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,906 | Primary thyroid teratomas: a clinicopathologic study of 30 cases. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Primary thyroid teratomas are rare thyroid gland neoplasms of germ cell derivation that display features of trilineage differentiation. [METHODS] The histologic and immunophenotypic features of 30 cases of thyroid teratomas were reviewed, patient follow-up was obtained, and the results were analyzed statis... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,905 | Medullary thyroid carcinoma: clinical characteristics, treatment, prognostic factors, and a comparison of staging systems. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1139::aid-cncr26>3.0.co;2-z | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] The clinical courses of patients with medullary thyroid carcinoma (MTC) vary, and a number of prognostic factors have been studied, but the significance of some of these factors remains controversial. [METHODS] The study group consisted of 104 patients with MTC or C-cell hyperplasia managed at the hospital... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,902 | Expression of MN/CA9 protein in Papanicolaou smears containing atypical glandular cells of undetermined significance is a diagnostic biomarker of cervical dysplasia and neoplasia. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1108::aid-cncr23>3.0.co;2-d | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Despite the enormous impact that Papanicolaou (Pap) smear screening has had on the incidence of cervical carcinoma in developed countries, there is still an unacceptably high frequency of occurrence of this cancer. In part, this is due to human error associated with cytologic diagnoses of Pap smears. Also,... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,900 | Mutant p53 protein overexpression in women with ipsilateral breast tumor recurrence following lumpectomy and radiation therapy. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] The p53 tumor suppressor gene encodes a nuclear phosphoprotein that is thought to be important to cell cycle regulation and DNA repair and that also may regulate induction of apoptosis by ionizing radiation. Somatic p53 gene mutations occur in 30-50% of breast carcinomas and are associated with poor progno... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,898 | Cutaneous fibrosis induced by docetaxel: a case report. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Docetaxel is a taxoid antineoplastic agent approved for use in the treatment of metastatic breast carcinoma. The current study reports an unusual case of generalized cutaneous fibrosis in a 39-year-old white female after treatment with 18 cycles of docetaxel for metastatic breast carcinoma. [METHODS] Cutan... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,896 | Analysis of prognosis and disease progression after local recurrence of melanoma. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1063::aid-cncr17>3.0.co;2-e | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Local recurrence of melanoma is associated with a grave prognosis. However, the characteristics and the mode of disease progression for patients with local recurrence have not been adequately addressed in the literature. [METHODS] A retrospective analysis of patients treated at a single institution reveale... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,895 | ATM gene deletion in patients with adult acute lymphoblastic leukemia. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1057::aid-cncr16>3.0.co;2-6 | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Loss of heterozygosity (LOH) at the ATM gene (mutated in ataxia telangiectasia [AT] patients) and ATM protein deficiency occur in 14% and 34%, respectively, of patients with chronic lymphocytic leukemia (CLL). ATM protein deficiency also is associated with aggressive disease and worse patient survival. Con... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,894 | Results of modern therapy for patients with mediastinal nonseminomatous germ cell tumors. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1051::aid-cncr15>3.0.co;2-r | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] The aim of this study was to determine the effects of independent prognostic variables, such as prechemotherapy tumor markers, the extent of disease at diagnosis, the tumor markers postchemotherapy (PC), and the pathology of the PC residual mass on the overall survival of patients with primary mediastinal ... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,893 | Phase I trial of docetaxel and vinorelbine in patients with advanced nonsmall cell lung carcinoma. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1045::aid-cncr14>3.0.co;2-j | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] With preclinical evidence of synergy, this dose-finding trial examining the combination of docetaxel and vinorelbine given with prophylactic filgrastim for the treatment of patients with nonsmall cell lung carcinoma was undertaken. [METHODS] Twenty-seven patients with advanced nonsmall cell lung carcinoma ... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,892 | Molecular detection of metastatic pancreatic carcinoma cells using a multimarker reverse transcriptase-polymerase chain reaction assay. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1037::aid-cncr13>3.0.co;2-h | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] The diagnosis of pancreatic carcinoma is often associated with a poor prognosis, because most patients already have advanced disease. A highly sensitive assay to detect the progression of pancreatic carcinoma would be of significant clinical utility. The authors developed multiple tumor mRNA markers for re... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,891 | p53 mutation pattern in hepatocellular carcinoma in workers exposed to vinyl chloride. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Vinyl chloride (VC) is a known animal and human carcinogen that is associated with liver angiosarcoma and most likely also with hepatocellular carcinoma (HCC) in humans. [METHODS] The authors examined the presence of p53 gene mutations in 18 HCC specimens from patients with known exposure to VC (median, 88... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,890 | Lack of frameshift mutations at coding mononucleotide repeats in hepatocellular carcinoma in Japanese patients. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Microsatellite instability occurs frequently in hereditary nonpolyposis colorectal carcinoma, in sporadic gastrointestinal carcinoma, and in other tumors. In these tumors, slippage-related frameshift mutations have been detected at coding mononucleotide repeats in genes such as those for transforming growt... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,888 | Preoperative treatment with tegafur suppositories enhances apoptosis and reduces the intratumoral microvessel density of human colorectal carcinoma. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<1007::aid-cncr9>3.0.co;2-6 | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] This study examined the effect of tegafur, a depot of 5-fluorouracil, in human colorectal carcinomas in terms of apoptosis, cell proliferation, and expression of p53 gene and angiogenesis-related molecules. [METHODS] A total of 32 patients with colorectal carcinoma were divided into 2 groups; 20 patients r... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,887 | Differences in diagnostic criteria for esophageal squamous cell carcinoma between Japanese and Western pathologists. | Cancer | Cancer | 88 | 5 | 10.1002/(sici)1097-0142(20000301)88:5<996::aid-cncr8>3.0.co;2-q | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Large discrepancies have been found between Western and Japanese pathologists in the diagnosis of adenoma/dysplasia versus carcinoma for gastric and colorectal glandular lesions. It is important to determine whether similar differences exist in the diagnosis of esophageal squamous lesions. [METHODS] Eleven... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,885 | Salivary flow and its relation with oral symptoms in terminally ill patients. | Cancer | Cancer | 88 | 5 | null | eng | 2,000 | 3 | 1 | null | null | null | [BACKGROUND] Patients with terminal malignant disease commonly report hyposalivation or xerostomia. This leads to "dry mouth," fungal infection, and mucosal abnormalities. To the authors' knowledge oral symptomatology and findings have not been correlated previously with accurate salivary flow measurements. [METHODS] M... | null | 1.528 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,820 | Surgery and obstructive sleep apnea: long-term clinical outcomes. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 122 | 3 | 10.1016/S0194-5998(00)70058-1 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] Outcome data on the surgical treatment of obstructive sleep apnea are, in general, based on short-term follow-up (<6-9 months). This examination was undertaken to assess long-term results. [METHODS] Forty patients who underwent soft tissue and skeletal surgery were the subjects of this review. Methods of ev... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,699,818 | Comparison of postoperative pain between laser-assisted uvulopalatoplasty, uvulopalatopharyngoplasty, and radiofrequency volumetric tissue reduction of the palate. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 122 | 3 | 10.1016/S0194-5998(00)70056-8 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] This study compares the posttreatment discomfort between laser-assisted uvulopalatoplasty (LAUP), uvulopalatopharyngoplasty (UPPP), and radiofrequency volumetric tissue reduction (RFVTR) of the palate through the use of visual analog pain scales and a quantitative assessment of the analgesic medication tak... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,699,807 | Preapplication of mitomycin C for enhanced patency of myringotomy. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 122 | 3 | 10.1016/S0194-5998(00)70045-3 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] Ventilation tubes are the mainstay of surgical treatment for eustachian tube dysfunction and have been used successfully for many years. Certain disadvantages of ventilation tubes, however, have prompted research into alternative techniques including laser myringotomy. We investigated the use of KTP laser ... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,699,806 | Endolymphatic mastoid shunt: a reevaluation of efficacy. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 122 | 3 | 10.1016/S0194-5998(00)70044-1 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] The main goal of this paper was to statistically reevaluate the efficacy of the endolymphatic shunt procedure for Meniere's disease. [METHODS] Thomsen et al (Arch Otolaryngol 1981;107:271-7) reported on the placebo effect in surgery for Meniere's disease in a controlled double-blind study. Thirty patients ... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,699,805 | Cost-effective management of benign positional vertigo using canalith repositioning. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 122 | 3 | 10.1016/S0194-5998(00)70043-X | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] The misdiagnosis and inappropriate treatment of benign positional vertigo have resulted in significant costs to the medical system. In the current medical-economic climate, there is an increased emphasis on cost control. Recent studies have shown that the canalith repositioning procedure (CRP) is effective;... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,699,803 | Vestibular dysfunction in Gulf War syndrome. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | Otolaryngol Head Neck Surg | 122 | 3 | 10.1067/mhn.2000.105783 | eng | 2,000 | 3 | null | null | null | null | [METHODS] Vestibular complaints of Gulf War veterans were characterized by a nested case-control study of 23 veterans with 3 different Gulf War syndromes and 20 matched control subjects. All subjects completed a standardized symptom questionnaire and underwent standard audiovestibular tests administered by audiologists... | null | 0.927 | 150 | Otorhinolaryngology; Surgery | Medicine | 2,000 |
10,699,785 | Endoscopic mucosal resection using a partial transparent hood for lesions located tangentially to the endoscope. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70365-8 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Numerous methods have been developed to resect early-stage gastric and esophageal cancers, but it is difficult to resect lesions viewed tangentially with the endoscope. [METHODS] We have designed and developed an original method of endoscopic mucosal resection using a partial transparent hood to treat diff... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,784 | Endoscopic bilateral metal stent placement for malignant hilar stenoses: identification of optimal technique. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70364-6 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] The aim of this study was to identify factors that facilitate bilateral insertion of metal stents in malignant hilar stenoses, for which plastic stents often result in incomplete drainage and subsequent cholangitis. [METHODS] Between January 1994 and April 1998, we collected 45 cases of advanced (Bismuth s... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,783 | Obliteration of esophageal varices using EUS-guided sclerotherapy with color Doppler. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70363-4 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] The current standard treatment of bleeding esophageal varices is band ligation. Although endoscopic sclerotherapy has largely been supplanted by band ligation, there are still clinical situations in which injection methods are useful. Endoscopic ultrasound (EUS) may allow for a more complete evaluation of ... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,778 | The prevalence, anatomic distribution, and diagnosis of colonic causes of chronic diarrhea. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70362-2 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] The prevalence of chronic diarrhea from a colonic disease and the optimal method of its diagnosis have not been ascertained. [METHODS] Eight hundred nine patients with chronic non-bloody diarrhea unassociated with human immunodeficiency virus (HIV) infection underwent colonoscopy with biopsy specimen taken... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,777 | Usefulness of a pediatric colonoscope for colonoscopy in adults. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70361-0 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] There are few published data on how different types of colonoscopes affect success in reaching the cecum and patient comfort. We examined the feasibility of using a pediatric colonoscope for routine colonoscopy in adults and investigated whether there were subgroups of patients in whom use of this instrume... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,776 | Dilation of malignant esophageal stenosis to allow EUS guided fine-needle aspiration: safety and effect on patient management. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70360-9 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Endoscopic ultrasonography (EUS) with fine-needle aspiration identifies patients with esophageal cancer who are unlikely to be cured by surgery. In approximately 30% of patients the staging procedure cannot be completed without dilation of an obstructing tumor. [METHODS] All EUS examinations for esophageal... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,775 | Small bowel polyps in Peutz-Jeghers syndrome: management by combined push enteroscopy and intraoperative enteroscopy. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70359-2 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Polyps occur throughout the GI tract in Peutz-Jeghers syndrome; the major problem in the management of the syndrome lies in the small bowel. [METHODS] From January 1979 to January 1998, seven patients with Peutz-Jeghers syndrome underwent surveillance. Between 1979 and 1992 they were managed with upper and... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,773 | A randomized, controlled trial of transcutaneous carbon dioxide monitoring during ERCP. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70357-9 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Pulse oximetry, used to monitor oxygen saturation during endoscopy, does not directly measure hypoventilation. Study goals were to determine whether transcutaneous carbon dioxide (PtcCO(2)) monitoring during endoscopic retrograde cholangiopancreatography (ERCP) prevents severe hypoventilation and to assess... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,771 | Patient-controlled analgesia for conscious sedation during colonoscopy: a randomized controlled study. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70355-5 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] The aim of this study was to assess whether patient-controlled anesthesia (PCA) can improve patient tolerance for colonoscopy. We compared baseline sedation and analgesia with baseline sedation and PCA. [METHODS] Fifty-six consecutive patients were alternatively allocated to 1 of 2 groups: either to contro... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,770 | Nitrous oxide for colonoscopy: a randomized controlled study. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70354-3 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Intravenous sedation/analgesia for colonoscopy is accompanied with certain risks and postprocedure drowsiness. We sought to determine whether inhaled nitrous oxide (Entonox: 50% nitrous oxide, 50% oxygen) provides adequate analgesia for colonoscopy and the impact of this agent on recovery. [METHODS] All pa... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,769 | A cost and performance evaluation of disposable and reusable biopsy forceps in GI endoscopy. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70353-1 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Biopsy forceps are widely used in gastrointestinal endoscopy, and yet few data exist on the usage and costs associated with disposable versus reusable forceps. [METHODS] We prospectively measured the costs and operational performance of disposable and reusable forceps in 200 biopsy sessions; 100 sessions w... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,768 | Disposable versus reusable biopsy forceps: a prospective cost evaluation. | Gastrointestinal endoscopy | Gastrointest Endosc | 51 | 3 | 10.1016/s0016-5107(00)70352-x | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] There is growing advocacy for the use of disposable medical accessories to reduce the risks of infection transmission. Their purchase costs can, however, be considered as prohibitive in an endoscopy unit operating under a cost-containment program. We therefore compared the costs of reusable and disposable ... | null | 0.614 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,696 | Possibilities of implementing dispatcher-assisted cardiopulmonary resuscitation in the community. An evaluation of 99 consecutive out-of-hospital cardiac arrests. | Resuscitation | Resuscitation | 44 | 1 | 10.1016/s0300-9572(99)00163-x | eng | 2,000 | 3 | null | null | null | null | [AIM] By evaluating tape recordings of true cardiac arrest calls, to judge the dispatchers ability to (a) identify cases as suspected cardiac arrest (CA), (b) give the case the right priority, (c) identify CA cases suitable for dispatcher-assisted, telephone-guided cardiopulmonary resuscitation (T-CPR) and (d) accompli... | null | 0.985 | 162 | Cardiology and Cardiovascular Medicine; Emergency Medicine; Emergency Nursing | Medicine; Nursing | 2,000 |
10,699,690 | Combined Nd-YAG laser/HDR brachytherapy versus Nd-YAG laser only in malignant central airway involvement: a prospective randomized study. | Lung cancer (Amsterdam, Netherlands) | Lung Cancer | 27 | 3 | 10.1016/s0169-5002(99)00102-6 | eng | 2,000 | 3 | null | null | null | null | [BACKGROUND] Laser debulking and prosthetic stents are useful modalities in the palliative treatment of initial inoperable or recurrent lung cancer. Recently, endobrochial brachytherapy was introduced to extend the duration of palliation and reduce the number of endoscopic treatments. This trial compares Nd-YAG laser a... | null | 0.576 | 154 | Cancer Research; Oncology; Pulmonary and Respiratory Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,000 |
10,699,682 | The biometrical comparison of cardiac imaging methods. | Computer methods and programs in biomedicine | Comput Methods Programs Biomed | 62 | 1 | 10.1016/s0169-2607(99)00048-6 | eng | 2,000 | 5 | null | null | null | null | [OBJECTIVES] Biometrical comparison procedures for cardiac imaging methods with continuous outcome are reviewed mainly concentrating on assessment and design adequate comparison of accuracy and precision. Univariate graphical and numerical representation of corresponding deviations is outlined to derive a 'check list' ... | null | 0.374 | 150 | Health Informatics; Software; Computer Science Applications | Computer Science; Medicine | 2,000 |
10,699,676 | Health insurance markets and income inequality: findings from an international health policy survey. | Health policy (Amsterdam, Netherlands) | Health Policy | 51 | 2 | 10.1016/s0168-8510(99)00084-6 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVE] To assess disparities in access to health care, financial burden of medical bills and perceived quality of care between those with above average incomes and those with below average incomes in five nations and to examine the relationship inequities in care experiences to health insurance coverage. [DESIGN] ... | null | 0.614 | 113 | Health Policy | Medicine | 2,000 |
10,699,635 | Expression of the human erythrocyte glucose transporter in transitional cell carcinoma of the bladder. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00474-4 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] It has previously been shown that glucose uptake and use is more prevalent in carcinomas than in normal cells and tissues. We hypothesized that human erythrocyte glucose transporter (Glut-1) expression is increased in bladder transitional cell carcinoma (TCC) and that the grade of expression might correlat... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,634 | Thoracoscopic transdiaphragmatic nephrectomy: feasibility study. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00469-0 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] Large-sized upper pole renal or adrenal tumors are often excised by the open thoracoabdominal approach. As an adjunct to existing transperitoneal and retroperitoneal laparoscopic approaches, we explore a novel minimally invasive technique, the thoracoscopic transdiaphragmatic approach, for performing nephr... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,624 | La Vega slit procedure for the treatment of phimosis. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00459-8 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] The surgical treatment of phimosis is usually circumcision. In countries in which circumcision is not widely practiced, this approach results in a phallus that is cosmetically unacceptable. We applied a ventral slit procedure to boys with severe phimosis and achieved outstanding results. [METHODS] All pati... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,623 | Efficacy and tolerability of tolterodine in children with detrusor hyperreflexia. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00477-x | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To investigate the urodynamic effects and tolerability of the new antimuscarinic drug tolterodine in children with detrusor hyperreflexia. [METHODS] Twenty-two children (12 boys and 10 girls; age range 3 months to 15 years, mean age 5.7 years) with detrusor hyperreflexia resulting in maximum detrusor press... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,621 | Diagnosing and treating chronic prostatitis: do urologists use the four-glass test? | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00536-1 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To examine the diagnosis and treatment of chronic prostatitis, we conducted a national mail survey of practicing urologists in 1998. [METHODS] Probability samples were drawn from the American Medical Association Registry of Physicians. [RESULTS] Five hundred four urologists responded (response rate 64%). U... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,620 | Endocrine status in elderly men with lower urinary tract symptoms: correlation of age, hormonal status, and lower urinary tract function. The Prostate Study Group of the Austrian Society of Urology. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00473-2 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To correlate endocrine parameters in elderly men with lower urinary tract symptoms (LUTS) to patient age and clinical parameters such as prostate volume, prostate-specific antigen (PSA) levels, and uroflowmetry and to compare the clinical and endocrinologic parameters in men with or without hypogonadism. [... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,617 | Does prolonged combined androgen blockade have survival benefits over short-term combined androgen blockade therapy? | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00574-9 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To explore whether less than 120 days of an antiandrogen plus a luteinizing hormone-releasing hormone agonist resulted in a different survival outcome than 120 days or more of combined treatment in patients with Stage D2 prostate cancer. [METHODS] Survival data were available from a previously published co... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,616 | Clinical characteristics in black and white men with prostate cancer in an equal access medical center. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00461-6 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To determine whether black men with newly diagnosed prostate cancer in an equal access health care center are more likely to present with metastatic disease, more poorly differentiated tumors, higher serum prostate-specific antigen (PSA) levels, and/or at younger ages compared with white men. [METHODS] A r... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,615 | Extent of extracapsular extension in localized prostate cancer. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00458-6 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To measure the radial extent of extracapsular penetration by tumor cells, thereby providing estimates of the margins needed around target volumes. New radiotherapeutic techniques, like brachytherapy and conformal radiotherapy, irradiate small volumes and reduce the dose to periprostatic tissues. Even in th... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,614 | Prognostic value of nuclear morphometry on needle biopsy from patients with prostate cancer: is volume-weighted mean nuclear volume superior to other morphometric parameters? | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00456-2 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To compare the prognostic value of stereologically estimated volume-weighted mean nuclear volume (MNV) with other nuclear morphometric parameters using pretreatment needle-biopsy specimens of prostate cancer. [METHODS] The MNV, mean nuclear area, form factor, and coefficients of variation for nuclear area ... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,612 | Gender differences in stage distribution of bladder cancer. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00481-1 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To compare stage distribution between men and women with bladder cancer at first presentation. [METHODS] The population-based Netherlands Cancer Registry was used to investigate stage differences of newly diagnosed bladder cancer, including upper urinary tract tumors in female and male patients. [RESULTS] ... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,610 | Combined intravesical and oral oxybutynin chloride in adult patients with spinal cord injury. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00540-3 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] Detrusor hyperreflexia with elevated storage pressures presents a major risk factor for renal damage in patients with neurogenic lower urinary tract dysfunction. If standard anticholinergic treatment is unsuccessful, surgical treatment must be considered. We evaluated the effects of intravesical oxybutynin... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,607 | Renal colic in pregnant women: role of renal resistive index. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00475-6 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To investigate the value of the renal resistive index (RI) in the identification of acute renal obstruction in pregnant women. [METHODS] The study included 22 pregnant women with acute unilateral ureteral obstruction due to a stone disease (group A), 71 normotensive pregnant patients without loin pain (gro... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,606 | Anesthetic aspects of laparoscopic and open adrenalectomy for pheochromocytoma. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00466-5 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To compare the anesthetic aspects and intraoperative hemodynamic data and immediate postoperative outcomes in patients whose pheochromocytoma resection was performed either laparoscopically or by traditional open surgery. [METHODS] Fourteen consecutive patients who underwent laparoscopic procedures (a sing... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,605 | Indications for surgical intensive care unit admission of postoperative urologic patients. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00445-8 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To analyze the practice of surgical intensive care unit (SICU) admission of postoperative urologic patients and to define objective criteria to predict active treatment requirements and length of stay in the SICU. [METHODS] The records of 90 consecutive patients admitted to the SICU postoperatively in the ... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,602 | Parenteral estrogen versus total androgen ablation in the treatment of advanced prostate carcinoma: effects on overall survival and cardiovascular mortality. The Scandinavian Prostatic Cancer Group (SPCG)-5 Trial Study. | Urology | Urology | 55 | 3 | 10.1016/s0090-4295(99)00580-4 | eng | 2,000 | 3 | null | null | null | null | [OBJECTIVES] To compare the effect on overall survival of total androgen ablation (TAA) with that of parenteral estrogen and to pay special attention to cardiovascular mortality. TAA (orchiectomy or a luteinizing hormone-releasing hormone analogue combined with an antiandrogen) has been proposed as superior to other en... | null | 1.753 | 197 | Urology | Medicine | 2,000 |
10,699,482 | Contractile properties of human renal cell carcinoma recruited arteries and their response to nicotinamide. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | Radiother Oncol | 54 | 2 | 10.1016/s0167-8140(99)00163-2 | eng | 2,000 | 2 | null | null | null | null | [BACKGROUND AND PURPOSE] The manipulation of tumour blood supply and thus oxygenation is a potentially important strategy for improving the treatment of solid tumours by radiation. Increased knowledge about the characteristics that distinguish the tumour vasculature from its normal counterparts may enable tumour blood ... | null | 1.283 | 189 | Hematology; Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,480 | Definition and validation of a reference target volume in early stage node-positive cervical carcinoma, based on lymphangiograms and CT-scans. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | Radiother Oncol | 54 | 2 | 10.1016/s0167-8140(99)00184-x | eng | 2,000 | 2 | null | null | null | null | [PURPOSE] To establish a reference planning target volume for postoperative radiotherapy in stage Ib and IIa N+ cervical carcinoma, based on 47 lymphangiograms and 15 CT-scans. [METHODS] Radiation oncologists (n=17) from all radiotherapy institutes in The Netherlands were asked to define the clinical target volume (CTV... | null | 1.283 | 189 | Hematology; Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
10,699,479 | Immediate toxicity during fractionated total body irradiation as conditioning for bone marrow transplantation. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | Radiother Oncol | 54 | 2 | 10.1016/s0167-8140(99)00178-4 | eng | 2,000 | 2 | null | null | null | null | [BACKGROUND] Total body irradiation followed by bone marrow transplantation is well established as a part of the conditioning regimen in high dose therapy. The immediate tolerance of fractionated total body irradiation (FTBI) was investigated prospectively. [METHODS] From January 1995 to December 1998 162 patients rece... | null | 1.283 | 189 | Hematology; Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,000 |
MedConclusion is a large-scale dataset of 5.7M PubMed structured abstracts for biomedical conclusion generation. Each instance pairs the non-conclusion sections of an abstract with the original author-written conclusion, providing naturally occurring supervision for evidence-to-conclusion reasoning. MedConclusion also includes journal-level metadata such as biomedical category and SJR, enabling subgroup analysis across biomedical domains.
This repository contains the full version of the dataset. For faster evaluation and model prototyping, please check out the Compact Version.
This dataset is introduced in the paper MedConclusion: A Benchmark for Biomedical Conclusion Generation from Structured Abstracts.
@article{li2026medconclusion,
title={MedConclusion: A Benchmark for Biomedical Conclusion Generation from Structured Abstracts},
author={Li, Weiyue and Qian, Ruizhi and Li, Yi and Li, Yongce and Long, Yunfan and Cai, Jiahui and Luo, Yan and Wang, Mengyu},
journal={arXiv preprint arXiv:2604.06505},
year={2026}
}