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5a897601fcd1d6a10c000008
[ 12007552, 22516994, 24705033, 8235662, 23172751, 28123902, 11480850, 16761499, 28116652, 12945718, 10955328, 15468356, 16354890, 25861457, 27365721, 17477466, 19762400, 16681575, 10685800, 28243944, 7993706, 2195948, 16150398, 27795838 ]
train
A SLEDAI score is associated with Systemic Lupus Erythematosus. What is a SLEDAI score?
summary
Disease activity of Systemic Lupus Erythematosis was evaluated according to the SLE Disease Activity Index (SLEDAI) score which score disease activity based on a number of parameters.
Disease activity of Systemic Lupus Erythematosis was evaluated according to the SLE Disease Activity Index (SLEDAI) score which score disease activity based on a number of parameters.
[ "Both the revised Systemic Lupus Activity Measure (SLAM-R) and the Systemic Lupus \nErythematosus Disease Activity Index (SLEDAI) are valid and reliable measures of \ndisease activity in systemic lupus erythematosus (SLE). However, more study of \ntheir responsiveness is needed. The purpose of this study was to com...
['http://www.disease-ontology.org/api/metadata/DOID:8857', 'http://www.disease-ontology.org/api/metadata/DOID:9074', 'https://meshb.nlm.nih.gov/record/ui?ui=D008180']
5a96c886fcd1d6a10c00002a
[ 24690977, 28319627 ]
train
A bite from the Lone Star Tick Amblyomma americanum, can cause the victim to become allergic to red meat, yes or no?
yesno
Conditions such as Southern tick-associated rash illness and anaphylaxis to red meat following tick bites have been attributed to the lone star tick, Ambyomma ameriacanum.
yes
[ "Delayed hypersensitivity disorders and food allergies are often challenging for \nthe clinician and patient alike. A recent discovery of an IgE antibody specific \nto galactose-α-1,3-galactose, which is a carbohydrate abundantly expressed on \ncells and tissues of beef, pork, and lamb, adds one more tool to aid th...
['https://meshb.nlm.nih.gov/record/ui?ui=D017282']
602346eb1cb411341a000090
[ 33139264, 34245216, 34522691, 34377156, 34051880, 34798793, 33442538, 33213161, 34189869, 33549983, 33663220, 34853653, 34771637, 32984090, 32349374, 34167423 ]
train
A combination of which two drugs was tested in the IMbrave150 trial?
list
IMbrave150 trial tested a combination of atezolizumab and bevacizumab for advanced hepatocellular carcinoma.
['atezolizumab', 'bevacizumab']
[ "On May 29, 2020, the FDA approved atezolizumab for use in combination with \nbevacizumab, for the treatment of adult patients with unresectable locally \nadvanced or metastatic hepatocellular carcinoma (HCC) with no prior systemic \ntreatment. The approval was based on data from Study IMbrave150, which randomly \n...
nan
515d7693298dcd4e5100000c
[ 22954629, 12872232, 20641139, 12422360, 12915006 ]
train
A common problem in proteomics is the contamination of samples with exogenous proteins (often from other species). These proteins can be found in specific databases. List some contaminants.
list
Some common contaminants in proteomics are proteases (used for the digestion of the proteins), keratins (usually from the skin), proteins originated from the serum of the culture media and antibodies if used in the experiment.
['Proteases', 'Keratins', 'Bovine serum proteins', 'Antibodies']
[ "Mass spectrometry is widely used in bioanalysis, including the fields of \nmetabolomics and proteomics, to simultaneously measure large numbers of \nmolecules in complex biological samples. Contaminants routinely occur within \nthese samples, for example, originating from the solvents or plasticware. \nIdentificat...
nan
5312280ce3eabad02100000a
[ 11037190, 21968521, 20635402, 8898827, 18463369, 15362573, 22436252, 22426657, 23966756, 9973290, 16723886, 9128751, 20644152, 23077562, 21596366, 21048783, 23713105, 10754001, 15340753, 18576213, 19335127, 17431895, 19918425, 24167642, 15675355, 15675354, 1817455...
train
Abnormalities in which chromosomes were linked to the Moyamoya disease?
list
chromosomes 3, 6, 8, 12, 15, 17, 21, X and Y were implicated in the Moyamoya disease.
['3', '6', '8', '12', '15', '17', '21', 'X', 'Y']
[ "Moyamoya disease is a specific chronic cerebrovascular occlusive disease first \nreported by Japanese surgeons in 1957. The disease is characterized by stenosis \nor occlusion of the terminal portions of the bilateral internal carotid arteries \nand abnormal vascular network in the vicinity of the arterial occlusi...
['http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D009072', 'http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D002875', 'http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005694', 'http://www.disease-ontology.org/api/metadata/DOID:13099', 'http://www.disease-ontology.org/api/metadata/DOID:0080014']
5313058de3eabad02100000e
[ 23096483, 21511940, 24156003, 8457417, 23969004, 16943469, 19547821, 19037900, 20624239, 19830065, 11154546, 18596536, 2533403, 19646556 ]
train
Abnormality in which vertebral region is important in the Bertolotti's syndrome?
factoid
Lumbosacral vertebral region is implicated in the Bertolotti's syndrome. Lumbosacral transitional vertebra is an anatomical variation of the fifth lumbar vertebra in which an enlarged transverse process can form a joint or fusion with the sacrum or ilium. Patients often complain of intractable sciatica that arises from impingement of the nerve root extraforaminally by compression caused by the enlarged transverse process.
lumbosacral
[ "BACKGROUND AND INTRODUCTION: In 1991, a deceased human male was found frozen in \na glacier pool in the Italian Alps in north west Italy, and is now carefully \npreserved in the South Tyrol Museum of Archaeology, in Bolzano, Italy. The \nbodily tissues of the 5,300 year old male (colloquially referred to as the \n...
['http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D013131', 'http://www.disease-ontology.org/api/metadata/DOID:225', 'http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D013577']
5a981e66fcd1d6a10c00002f
[ 23519746, 26280340, 17137436, 28106792, 23145009, 16762931, 10682170, 18497723, 10863169, 26543426, 17125447, 19108808, 12137304, 15827427, 26871396, 11276389, 15940204, 12148078, 17469041 ]
train
According to guidelines, insulin resistance is one risk factor in the diagnosis of metabolic syndrome, name 3 more risk factors.
list
Metabolic syndrome (MetS) is generally defined as a cluster of metabolically related cardiovascular risk factors which are often associated with the condition of insulin resistance, elevated blood pressure, and abdominal obesity.
['obesity', 'hypertension', 'dyslipdemia']
[ "Obesity and overweight are nowadays very prevalent worldwide. They are known to \nbe linked with an increased risk of developing cardiovascular comorbidities and \nmortality. Abdominal obesity is frequently associated with a collection of \nmetabolic disorders that include elevated blood pressure, characteristic l...
['https://meshb.nlm.nih.gov/record/ui?ui=D024821', 'https://meshb.nlm.nih.gov/record/ui?ui=D007333']
61f5914e882a024a1000000d
[27582220,34554383,33135381,34366359,34506904,34827546,34550687,29067304,29686315,29181491,34697913,(...TRUNCATED)
train
Aducanumab can be used for treatment of which disease?
factoid
Aducanumab is approved for treatment of Alzheimer's disease.
Alzheimer's disease
["Alzheimer's disease (AD) is characterized by deposition of amyloid-β (Aβ) \nplaques and neurofib(...TRUNCATED)
nan
53189656b166e2b80600001c
[9600226,12536227,19272424,9759660,10967182,16691119,11005264,12722831,15854770,10867800,22370907,10(...TRUNCATED)
train
Against which protein is the antibody used for immonostaining of Lewy bodies raised?
factoid
"alpha-Synuclein is a presynaptic protein, which was identified as a specific component of Lewy bodi(...TRUNCATED)
alpha-Synuclein
["A mutation in the alpha-synuclein gene has recently been linked to some cases of \nfamilial Parkin(...TRUNCATED)
"['http://www.uniprot.org/uniprot/SYUA_SERCA', 'http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=ui(...TRUNCATED)
515a9d86d24251bc050000a7
[ 18288611, 15822917, 16335978, 19327347, 21906361, 15952730, 18412540, 23300121 ]
train
"Albumin depletion is a common first step for proteomic analysis of CSF fluid. What is the advantage(...TRUNCATED)
summary
"Depletion of the high abundant protein Albumin from CSF samples is improving the detection of lower(...TRUNCATED)
"Depletion of the high abundant protein Albumin from CSF samples is improving the detection of lower(...TRUNCATED)
["Glycoproteins in cerebrospinal fluid (CSF) are altered in Alzheimer's Disease \n(AD) patients comp(...TRUNCATED)
"['http://www.nlm.nih.gov/cgi/mesh/2012/MB_cgi?field=uid&exact=Find+Exact+Term&term=D005441', 'http:(...TRUNCATED)
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