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Methods and materials: The patients who enrolled in this ethics approved Phase 1 prostate cancer trial were treated with a variable combination of targeted photo-dynamic therapies and coupled ultrasound energies, mediated through orally/sub-lingually administered chlorophyll based photosensitisers. The metronomic techn... |
over set time intervals. As scientific assessment of the prostate cancer effects, intra-treatment fluorescent photography of the prostate gland /prostatic fossa, together with proteomic based urine specimen studies were performed. |
Results: The clinical data involved 666 treatment episodes, 333 photosensitiser dosages and includes 3-5 years patient follow-up. The effects on the prostate symptoms and cancer are documented, prostate size reduction being a serendipitous finding. Real time fluorescent photography has documented qualitative reproducib... |
documentation of the known pathological effects, attributable to this treatment. |
Conclusion: This study has been shown to be safe and to meet the criteria required of a TGA Phase 1 trial and reports the clinical and investigational prostate cancer responses to the metronomic therapy, involving the three different photosensitisers. The scientific bases for this therapy have been validated with the r... |
The Palmer Deep submarine canyon on the Western Antarctic Peninsula provides a conduit for upwelling of relatively warm, nutrient rich waters which enhance local primary production and support a food web productive enough to sustain a large top predator biomass. In an analysis of ten years of satellite-tagged penguins,... |
In order to reduce the cost and establish the wireless network for smart home system, and realize the integration of router and smart home control gateway, this paper proposes a low-cost design of routing gateway for smart home. With Openwrt open source routing system and Luci WEB framework, using WiFi and Zigbee as th... |
Total and differential leucocyte counts have been determined by electronic counting techniques in 474, two-to-four-year-old healthy Thoroughbreds in training. The ranges of values observed (particular those for neutrophils and lymphocytes) were narrower than previously described. Absolute and percentage lymphocyte valu... |
Experimental studies have shown that a sharp, high-frequency IR band at ~3615 cm-1 (in H2O form) and at ~2685 cm-1 (in D2O form) is a common feature for all smectites, and its position correlates with layer charge. In order to explain the molecular origin of this band in terms of total layer charge, charge localization... |
Introduction: |
The benefit of thrombectomy for large vessel occlusion (LVO) is well proven. There is minimal data on concurrent thrombectomy for multi-territory occlusions. |
Methods: |
We reviewed the STAR registry from 2015-8 for patients treated with either right and left sided thrombectomy or anterior and posterior circulation thrombectomy at 15 comprehensive stroke centers. |
Results: |
There were 4966 patients in the study period who had completed outcome data and LVO thrombectomy. 38 (0.8%) underwent endovascular thrombectomy for multi-territory occlusions. 26% had bilateral occlusions and 74% had anterior and posterior circulation occlusions. Among the 38, 50% were female, 49% were white, and 91% ... |
Conclusion: |
With similar selection to single territory LVOs, good outcome can be achieved in multi-territory infarction with reasonable procedure time and no additional risk of hemorrhage or poor outcome. |
The seven ages of woman - a lifetime guide to feeling good Rosemary Leonard The seven ages of woman - a lifetime guide to feeling good Bantam Press 470pp £14.99 978 0 593 05516 8 9780593055168 [Formula: see text]. |
If you are looking for a general guide to women's health for the lay person, this book fits the bill. Covering a wide range of topics, it outlines health-related issues from childhood through to adulthood - a true cradle to grave approach. It looks at child health, pregnancy, contraception, sexually transmitted infecti... |
This paper presents a secondary voltage control scheme for microgrids based on the port-Hamiltonian modeling framework. The proposed secondary controller compensates the deviations of voltage amplitudes from their nominal values using the concept of energy shaping, which is the essence of passivity-based control in por... |
The gene amplification and expression of transforming growth factor-alpha (TGF-alpha) and the epidermal growth factor receptor (EGF-R) in human gliomas was determined by Southern blot analysis and a receptor binding study. Amplification of the EGF-R gene was demonstrated in 3 of 11 tumors examined. All were glioblastom... |
Several applications have been implemented since the rise of autonomous and intelligent vehicles. These applications include, but are not limited to, self-driving cars, warehouse management and automated factories. However, in the past few decades, research in this field was heavily directed towards the investigation o... |
The goal of this paper is to find out the combination point, through analyzing the characteristic of sustainability and product design process, and propose a set of design principles of sustainability which are suitable for product design process. In the process of product design, considering sustainability in parallel... |
Intergroup discrimination in the minimal group paradigm (MGP), which is usually invoked in support of social identity theory (SIT), seems to contradict every principle of social justice. A contradiction to equity theory (ET), however, exists only if one is committed to the transferability of ET from intragroup to inter... |
The project aims to investigate the possibility of VR in a combination of visualizing high-dimensional urban data. Our study proposes a data-based tool for urban planners, architects, and researchers to 3D visualize and experience an urban quarter. Users have a possibility to choose a specific part of a city according ... |
Probe permeameter (also known as Mini-permeameter) has been widely used in many field and laboratory applications where in-situ measurements and spatial distributions of permeability are needed. Mini-permeameter measurements have become popular techniques for collecting localized permeability measurements in both labo... |
In this work, the effect of vertical and horizontal anisotropy on the probe permeameter measurements was investigated. A numerical simulation model for the rectangular system representing a porous rock sample was built based on finite difference discretization of steady-state flow of an incompressible single-phase flu... |
The results obtained showed the clear effect of anisotropy on the probe permeameter measurements and were expressed in dimensionless parameters. These dimensionless parameters include the ratio between the flow rate measurements at different directions for different vertical and horizontal anisotropy ratios. They also... |
ABSTRACT The school playground provides a natural context for play observation for children of all abilities. However, play promoters interested in designing and assessing playground interventions are limited by a lack of quantitative observation tools to measure playground play sophistication for groups of children. W... |
A population-based case-control study to determine social and behavioural risk factors for Taenia solium cysticercosis in humans was carried out in a rural area, Shandong province, China. Forty-eight cases with cysticercosis were ascertained through a prevalence survey conducted among 7281 persons in 1993. For each cas... |
Calculation results are showing: There are basically specific relationships between loading machine’s weight and loading machines’ main parameters or other parameters’ combinations. So these specific relationships have certain similarity. And machine’s similarity criteria has invariance. The similarity equations derive... |
Recent reports indicate continuing rises in the height and weight of schoolchildren in both developed and developing populations. Also indicated are increases in the body mass index of children, and of adults, despite all public health warnings to the contrary, as well as personal desires of huge proportions of childre... |
Abstract Background : The role of hemolysis in the pathophysiology of neonatal jaundice (NNJ) in patients with glucose 6‐phosphate dehydrogenase (G6PD) deficiency has been questioned recently. The aim of the present study was to determine the contribution of hemolysis to the pathophysiology of jaundice in Malay neonate... |
Intelligence is extremely critical for firms to evaluate competitive environment, grasp opportunities, gain advantages and cope with crisis. The emergence of big data has created new opportunities and more challenges for firms to identify and use intelligence effectively. This paper attempts to explore a multidimension... |
This article describes the evolution of forensic interviewing as a method to determine whether or not a child has been sexually abused, focusing primarily on the United States. It notes that forensic interviewing practices are challenged to successfully identify children who have been sexually abused and successfully e... |
† This study evaluated the supplemental feeding program to address undernourishment among 59 pupils in an elementary school located in one of the depressed communities in Tarlac City, Philippines. Before the feeding program and vitamin supplementation, pupils were found to have Body Mass Indices below normal values. Th... |
How to resolve the resources exploration in deep and surrounding of the crisis mines is a very urgent problem which confronts with mining industry. Choosing the suitable prediction theory and technology is the key to success in evaluating. According to the particularity of resource exploration in deep and surrounding o... |
1. Brief history of the use of solar energy to transform matter 2. Main characteristics of solar furnaces 3. Elaboration of materials using concentrated solar energy 3.1 Surface treatments 3.2 Melting and purification of bulk materials 3.3 Production of chemical commodities and ceramics 3.4 Elaboration of carbon molecu... |
: This study presents the design analysis and correlation properties of a new spreading code for the incoherent synchronous pulse position modulation-optical code division multiple access (PPM-OCDMA) networks. The proposed code called optimised modified prime code (OMPC), which refers to the modified prime codes (MPCs)... |
Discovering communities from a social network requires publishing the social network's data. However, community detection from raw data of a social network may reveal many sensitive information of the involved parties, e.g., how much a user is involved in which communities. An individual may not want to reveal such sen... |
The Walsh-Hadamard transform plays a major role in many image and video coding algorithms. In one hand, its intensive use in these algorithms makes its acceleration a challenge, in order to speed-up the algorithm execution. On the other hand, the available fast implementations are not efficient across different platfor... |
As guest editors we sincerely wish to thank all the authors who readily accepted the invitation to submit an original paper for this special issue of the Journal of Sulfur Chemistry dedicated to the memory of our colleague and friend Alessandro Degl’Innocenti. The outstanding reputations of these authors in the organic... |
This paper examines the relationship between capital structure and firm performance and considers the moderating effect on this relationship of the issuance of International Financial Reporting Standards (IFRS) 16. The study sample consists of 101 Saudi nonfinancial firms listed on the Tadawul between 2017 and 2020. Th... |
State-of-the-art learning algorithms accept data in feature vector format as input. Examples belonging to different classes may not always be easy to separate in the original feature space. One may ask: can transformation of existing features into new space reveal significant discriminative information not obvious in t... |
To study serum thyroglobulin (Tg) levels in patients with thyroid disorders compared to sex- and age-matched control subjects and to correlate the Tg levels to the thyroid function, 71 patients were investigated before treatment was started. Serum Tg, measured by a double antibody radioimmunoassay, was elevated in all ... |
As a result of the analysis of scientific-methodical, special and reference literature (monitoring of Internet resources), members of the Research Group found that the analytical review of Technical and Tactical training of highly qualified combat Sambo wrestlers (participants of the 2021 World Cup, Tashkent, Uzbekista... |
The main Purpose of the study is to analyze the Technical and Tactical arsenal of highly qualified combat Sambo wrestlers (Top – 3, men's), participants of the "World Championship – 2021, Tashkent, Uzbekistan". The following research methods were used in the process of research and analytical work: abstraction, measure... |
As a result of Theoretical research, members of the Research Group analyzed the Technical and Tactical arsenal of highly qualified combat Sambo wrestlers (top-3, men's), participants of the "World Championship – 2021", Tashkent, Uzbekistan.Space, innovation and the locus of knowledge: an ontological response to Rutten |
Marc Bahlmann is assistant professor at VU University Amsterdam. He received his Ph.D. from the Faculty of Social Sciences (VU University) for a study on knowledge dynamics among IT entrepreneurs located in the Amsterdam IT and new media cluster. His current research interests include alliance portfolios, organizationa... |
Increasing variability not only affects the behavior of contemporary ICs but also their vulnerability to transient error phenomenon especially radiation induced soft errors. Such variations in device parameters are caused by static process variations, dynamic variations in power supply and temperature and slow degradat... |
We have performed atomistic simulations on solid and hollow copper nanowires to quantify the elastic properties of hollow nanowires (nanoboxes). We analyse variations in the modulus, yield stress and strain for and nanoboxes by varying the amount of bulk material that is removed to create the nanoboxes. We find that, w... |
Let be a point sequence in the unit disc and the Nevanlinna characteristic of the sequence , . In terms of the Nevanlinna characteristic one finds estimates for the slowest possible growth of the characteristic as in the class of holomorphic functions in vanishing on . Let be a meromorphic function in . In terms of the... |
Abstract In this study, bio-sludge from a vegetable oil refinery effluent treatment plant was taken. The Proximate, ultimate, and elemental analyses of bio-sludge were done. Microwave-assisted fast pyrolysis using Box-Behnken design response surface methodology was applied to investigate the optimum conditions to produ... |
Abstract Fetal electrocardiogram (ECG) monitoring from the mother’s abdomen during pregnancy provides electrophysiological statistics of fetus heart. To separate fetal ECG from mother ECG is a signal separation technique that has the potential to give blind source information. In this paper, an empirical sequence of Ke... |
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