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children with AML. Despite all of it, ML-DS survival rates for children |
in low- and middle-income countries (LMICs) remain poor. We described |
three ML-DS cases, which were treated with vincristine, cytarabine and |
daunorubicin plus triple intrathecal drugs. All of our three patients |
successfully finished the treatment, with two patients were still |
complete remission until now, and one died two days after finishing the |
chemotherapy. ML-DS is treatable in our limited-resources setting in |
Manado, Indonesia.Design and Development of Semantic Application for Communities |
In the recent years, social applications have competed to incorporate emerging technologies and innovative aspects like semantics technologies, location based services, data ephemerality to ensure user privacy, etc. Although few applications combine these aspects, our challenge is to gather them in applications for com... |
This article describes the speech signal fundamental frequency evaluation algorithm in view of speech formation and speech perception features connected with human anatomy and physiology, using mathematical apparatus of singular spectrum analysis for speech signal processing, for further implementation of the speech si... |
This set of contributions to the journal is in memory of Professor Alan Bryman, who passed away on 20 July 2017. Alan was Professor of Organisational and Social Research at the University of Leicester from 2005, prior to which he had spent three decades at Loughborough University. He had a longstanding interest in soci... |
A nonlinear two‐core fiber coupler with unequal cores (phase‐mismatched) is analyzed by using coupled‐mode theory. Based on the solutions of the coupled‐mode equations, it is demonstrated that even though there is a difference in core diameter, the unequal‐core fiber coupler (phase‐mismatched) can function as a twin‐co... |
ABSTRACT The pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), are mainly under the control of hypothalamic gonadotropin-releasing hormone (GnRH), which regulates male and female gonadal function. GnRH is released in a pulsatile manner from the hypothalamus, and the frequency of ... |
This thesis describes the preparation of some alkylideneamino derivatives containing groups R(_2)C:N-attached to lithium, boron, aluminium, gallium, silicon and phosphorus, compounds which were prepared with the object of finding model systems for the study of dative N=M-bonding between nitrogen and these elements. Sys... |
<p>Imagery products are critical for digital agriculture as they help delivering value and insights to growers. Use of publicly available satellite data feeds by digital agriculture companies helps keeping imagery services affordable for broader base of farmers. Optimal use of public and private imagery data sources p... |
Law and Medicine |
T H E author will limit himself to a subject that has hardly seen the light of day in Nigeria, a subject which any nation can only reject if it is willing to pay the price of injustice in its stead. This refers to Legal Medicine. I t can be defined approximately as ' the application of medical knowledge to the administ... |
The high cost of cellular phone purchase and service still prices them out of reach of many consumers. However, the marriage of cordless phone technology to radio pagers offers the promise of a low cost device with much of the functional capability of cellular phones at a fraction of the cost.<<ETX>>Luteinizing hormone... |
The gonadotropic hormones, LH and FSH, activate adenylyl cyclase in their respective target cells and thereby initiate many biochemical responses. In addition to stimulating cAMP production, both LH and FSH promote agonist-specific increases in the cytoplasmic concentration of free calcium ions ([Ca2+]i) in gonadal cel... |
This article aims to demonstrate the concept and potential of a novel diagnostic device – the nasal acoustic device (NAD), which captures the nasal breathing sounds over the ala on both sides of the nose. Using the newly defined inspiratory nasal acoustic score (INA score), the unique characteristics of the nasal breat... |
For the sake of credibility the ECB has to commit to a clear policy strategy a direct inflation target or an intermediate monetary target. We offer some information on the scale of control and indicator problems associated with both strategies. We estimate the links between monetary policy actions and inflation in dyna... |
Searchable encryption is an important research area in cloud computing. However, most existing efficient and reliable ciphertext search schemes are based on keywords or shallow semantic parsing, which are not smart enough to meet with users’ search intention. Therefore, in this paper, we propose a content-aware search ... |
Aiming at the complicated conditions of wind farm, this paper proposes a semi-physical simulation system that can simulate the operation of wind turbine under laboratory conditions. First, gives simulated wind velocity that based on ARMA and statistical wind velocity model, and then utilizes field data to make Power Sp... |
An increasing number of clinical isolates of vancomycin resistant enterococci (VRE) have been reported in the literature since 1988. Only a few cases of beta-lactamase producing VRE have been described worldwide. This article reports the first case of beta-lactamase positive VRE in Australia. This strain of Enterococcu... |
Since the attention of the profession was called to ade ... noid vegetations, or hypertrophy of the pharyngeal tonsil, by Wilhelm Meyer, the subject has received much consideration and has been the theme of numerous monographs. It is now universally conceded by all who are best qualified to judge, that lymphoid hypertr... |
This paper presents a methodology to assess operating reserves in isolated power systems under high penetration of wind power. The methodology is based on a convolution approach that merges the fluctuations of wind speed with the natural variations of demand, and formulates the probability distribution function of vari... |
ObjectiveTo evaluate the safety and antiretroviral activity of nelfinavir mesylate at two doses as part of a combination regimen in HIV-infected, antiretroviral-naive patients. DesignPhase III, multicenter, double-blind, placebo-controlled trial. Patients and methodsTwo-hundred and ninety-seven patients were randomized... |
Oxygen reduction reaction (ORR), an essential reaction in metal-air batteries and fuel cells, still faces many challenges, such as exploiting cost-effective nonprecious metal electrocatalysts and identifying their surface catalytic sites. Here we introduce bulk defects, Frank partial dislocations (FPDs), into metallic ... |
In mammalian thermosensation, nine temperature-sensitive ion channels that are activated by distinct temperature thresholds have been identified as thermosensors. These ion channels belong to the transient receptor potential (TRP) superfamily and are referred to as "thermoTRPs" (TRPV1, TRPV2, TRPV3, TRPV4, TRPM2, TRPM4... |
The efficacy of antidepressants in the acute treatment of moderate-to-severe depression remains a controversial issue. The minimal important difference (MID) is relevant to judge the clinical significance of treatment effects. In this analysis paper, we discuss estimates of the MID for common depression outcome measure... |
Glycosylated fetal hemoglobin levels were measured in umbilical cord blood of normal infants and infants of diabetic mothers. The glycosylated fraction proved to be a stable compound; its level remained unchanged over a 19-day period. Exposure of fetal and adult hemoglobins to the same concentrations of glucose in vitr... |
MBE-based SiGe/Si heterostructures prepared by molecular beam epitaxy (MBE) are described in this study with an aim at manufacturing SiGe heterojunction bipolar transistors (HBTs) for the applications in analog ICs. Based on the simulations made by Medici, MBE-based SiGe/Si heterostructures have been designed and grown... |
BACKGROUND: Low rectal cancers are associated with worse outcomes in comparison with mid and upper rectal tumors. OBJECTIVE: This study aimed to assess the predictive accuracy of MRI in identifying the correct surgical approach based on the mesorectal and extralevator planes. DESIGN: This study involved the retrospecti... |
BACKGROUND |
Reoperations for bypass surgery increase the need for new grafts. We investigated early changes in both the normal human saphenous vein and in ectatic varicose veins externally supported by PTFE (polytetrafluoroethylene) graft and exposed to arterial pressure in an IN VITRO non-pulsatile flow model. |
MATERIAL AND METHODS |
A total of 24 saphenous vein pieces (11 of them normal, the other 13 with varicosities) with a length of 6 centimeters were divided into equal parts; half of these parts were wrapped in PTFE grafts. All vein parts were placed in a perfusion circuit. Tissue biopsies were obtained from the vein segments. Light and electr... |
RESULTS |
All parameters in the PTFE protected vein groups were better. The fewest morphological changes among all four groups were detected in the vein walls from normal veins with PTFE protection. There was no significant difference in endothelial continuity and adventitial connective tissue uniformity between the normal vein ... |
CONCLUSIONS |
It is suggested that supporting vein grafts externally with PTFE sufficiently protects the vein walls against damage from exposure to arterial pressure. If varicose veins are used as arterial grafts, supporting them with PTFE may be useful because of the good protection of endothelial and medial connective tissues, res... |
In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of diabetes/metabolism. Each bibliography is divided into 26 sections: 1 Reviews;... |
A discrete image flux conduction equation which is completely new in this field is proposed. The new approach starts with formulating a discrete image flux conduction equation based on the concept of heat conduction theory. Based on this discrete equation, the status change at a time point can be directly computed from... |
Hesperaloe funifera and H. nocturna are currently being studied as potential new sources of fibers for specialty papers. This study investigated canopy architecture and light interception in H. funifera, and gas exchange in both species. H. funifera is an acaulescent rosette species with stiff, upright leaves. Mean lea... |
Sporadic amyotrophic lateral sclerosis is a motor neuron disease of unknown origin. Autoimmunity against voltagegated calcium channels is one mechanism hypothesized to be the cause of the disease. In support of this hypothesis, it was previously reported that amyotrophic lateral sclerosis IgG specifically blocked the b... |
Abstract With an increase in life expectancy and decrease of quality-of-life couple with the high prevalence of diseases, diet is expected to play a key function in sustaining human health. Nutritionists, food technologists and medical experts are working in synergy to cater for the increasing demand of food with assoc... |
Social innovation represents a social practice that aims to meet social needs by involving communities in dialogues through participatory and collaborative approaches. One new and particular solution of social innovation is represented by Urban Civic Networks. However, considering the novelty of this topic, neither the... |
Genomics and neuroscience represent two areas of science fundamental to understanding the brain, and thus, fundamental to psychiatry. By any measure, they have undergone revolutionary changes in the past twenty years. Yet methods of diagnosis and treatment for patients with mental disorders have remained relatively unc... |
In this essay we argue that psychiatry’s impact on public health will require that mental disorders be understood and treated as brain disorders. In the past, mental disorders were defined by the absence of an “organic” lesion. Mental disorders became neurological disorders at the moment a lesion was found. With the ad... |
Gentamicin (GT) was administered IM to 6 healthy mature mare ponies at a dosage of 5 mg/kg of body weight every 8 hours for 7 consecutive days (total, 21 doses). Two venous blood samples were collected before (trough) and at 1 hour (peak) after the 5th, 10th, 14th, and 19th doses. An endometrial biopsy was done of each... |
In this study, the Chinese mitten crabs, Eriocheir sinensis were exposed to avermectin at 0.03, 0.06, 0.12, 0.24, and 0.48 mg/L respectively for 96 hours. The results showed that levels of superoxide dismutase, catalase, and glutathione peroxidase in hepatopancreas were slightly induced at concentration of 0.03 and 0.0... |
Power and energy consumption are seen of one of the most critical design factor for any next generation large-scale HPC system. The price centers have to pay for energy is shifting the budgets from investment to operating costs, leading to scenarios in which the sizes of systems will be determined by their power needs,... |
ObjectiveTo determine the age-specific and age-adjusted prevalence of osteopenia and osteoporosis in pre-and postmenopausal Thai women. MethodsThis was a descriptive study of 1,935 Thai women ranging in age from 40 to 80 years, with randomly selected strata using multistage sampling and stratifying from six representat... |
We report on measurements of residual stress up to 300 MPa with a microfocused synchrotron X-ray beam in quartz fragments in a cataclasite from the damage zone of the San Andreas fault, California (USA). Samples were extracted from the San Andreas Fault Observatory at Depth drill core at a depth of 2.7 km. Stresses wer... |
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