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CONCLUSION |
Exposure to vanadium can adversely affect neurobehavioral functions of workers. Workers exposed to vanadium may show mood disorders, decreased vision-memory, and declined motor speed and accuracy.A Cross-sectional Study of Serum Levels of Zinc, Copper and Magnesium in Type 2 Diabetes Mellitus in South Indian Urban Popu... |
Introduction: Variability in the levels of these trace elements may reflect altered insulin metabolism and poor glycaemic control in the background of elevated oxidative stress. Mineral metabolism is another entity that may be disrupted by diabetes mellitus. Conversely, there are studies implicating early imbalances of... |
Service-oriented architectures (SOA) become more and more important in networked embedded systems. The main advantages of Service-oriented architectures are a higher abstraction level and interoperability of devices. In this area, Web services have become an important standard for communication between devices. However... |
SiO2 and related dielectrics are basic constituents of many optical and electronic devices with applications in frontier optoelectronics as well as in many radiation and harsh environments. The ongoing activity of researchers ranges from fundamentals of the electron processes, including defects formation and radiation-... |
Early North American railways chose different track gauges partly on the basis of differing engineering traditions and partly for mutual compatibility. The resulting dynamic process produced nine district common-guage regions by the 1860s. Growing demand for interregional traffic and increasing among railways yielded i... |
ABSTRACT Although most neuromuscular disease research articles reflect traditional quantitative approaches, qualitative methods are becoming more prevalent in the neuromuscular literature. Arguably, qualitative research provides rich data that may be used to generate patient-centered outcome measures or influence curre... |
To solve the task of surgical mask detection from audio recordings in the scope of Interspeech’s ComParE challenge, we introduce a phonetic recognizer which is able to differentiate between clear and mask samples. A deep recurrent phoneme recognition model is first trained on spectrograms from a German corpus to learn ... |
In this paper, we investigate the fault detection problem for a class of discrete-time non-linear networked systems with Markovian network-induced delays. It is assumed that networks exist in both communication channels from the sensor to the controller and from the controller to the actuator. The transmission delays o... |
Imprinted expression of the mouse Igf2/H19 locus is controlled by parent-of-origin-specific methylation of the imprinting control region (ICR). We previously demonstrated that when placed in a heterologous genomic context, the H19 ICR fragment contains an intrinsic activity that allows it to acquire differential methyl... |
This paper addresses a resource selection problem for applications that update data in enterprise grid systems. The problem is insufficiently addressed as most of the existing resource selection approaches in grid environments primarily deal with read-only job. We propose a simple yet efficient algorithm that deals wit... |
The rapid evolution of mobile communication networks is due to the large increase in the number of users. But higher throughput is not the only criterion to address the fifth generation of cellular networks. It mainly focuses on the redressal of the possible issues of the networks. The mostly found issues are lesser ar... |
Lysosomes are essential acidic cytoplasmic membrane-bound organelles in human cells that play a critical role in many cellular events. A comprehensive understanding of lysosome-specific imaging can ultimately help us to design robust organelle-targeting therapeutic reagents for various underlying human diseases. Lumine... |
n his latest book, We Won’t Budge: An African Exile in the World (2003), Manthia Diawara provides a multifaceted assessment of African modernity, a theme at the forefront of all his major works, such as the documentary film Rouch in Reverse (1995) or In Search of Africa (1998). Diawara engages African modernity concept... |
A method for separating low molecular cryoprotectiva from freeze-conserved erythrocyte- and thrombocyte-concentrates by exclusion chromatography has been described. A new vesicular packing material has been used. Only 25 to 30 minutes are necessary in order to separate glycerol respectively dimethylsulphoxide (DMSO) co... |
BACKGROUND |
Long non-coding RNAs (lncRNAs) X-inactive specific transcript (XIST) has identified to involve into the tumor cell angiogenesis. However, whether XIST contributes to Human Brain Microvascular Endothelial Cells (HBMEC) angiogenesis as well as potential mechanisms are largely unclear. |
METHODS |
The expression of XIST, miR-485-3p and SRY-box 7 (SOX7) in HBMEC were altered by transfection. The cell viability, cell migration and tube formation of HBMEC were measured, respectively. The cross-regulations between XIST, miR-485-3p, SOX7, and vascular endothelial growth factor (VEGF) signaling pathway were investigat... |
RESULTS |
In this study, we characterized the upregulation of XIST in HBMEC under hypoxia condition. Meanwhile, XIST silencing impaired hypoxia-induced cell proliferation, migration and tube formation. Besides, our integrated experiments identified that XIST may competitively bind with miR-485-3p and then modulate the derepressi... |
CONCLUSION |
Altogether, the present study suggested that XIST is required to maintain VEGF signaling expression in HBMEC under hypoxia condition and plays a vital role in hypoxia-induced angiogenesis via miR-485-3p/SOX7 axis.The Affordable Care Act: Opportunities and Challenges for Physicians |
AbstractThe Affordable Care Act (ACA) will affect many aspects of health care across the nation, presenting both opportunities and challenges. Physicians who have a solid understanding of the recent industry trends and the role they will be playing in the post-ACA world will be able to better adapt to the new environme... |
In this paper, a new model to grade cured tobacco leaves using symbolic data is proposed. Color features such as average and standard deviation of hue of tobacco leaves are extracted using the Munsell color system. The extracted features of each grade are aggregated and represented in the form of inter-valued type data... |
This paper describes the use of the Big Packet Protocol (BPP) for carrying video from servers to clients, and how SDN controllers can effectively manage the flow-rate and QoE, based on the available bandwidth. BPP relies on meta-data being injected into packets in order to provide information for network nodes on how t... |
Abstract Microstructural post mortem changes to skeletal tissues by microorganisms are driven by several factors including the death history of an animal, its decomposition trajectory, and the depositing environment itself. The study we describe here brings together material from recent and fossil contexts that are dep... |
Using routine stable isotope dilution/gas chromatography-mass spectrometry, 17-hydroxyprogesterone, androstenedione, testosterone, dehydroepiandrosterone, androstanediol, and 5alpha-dihydrotestosterone have been profiled in amniotic fluid of midgestation in 77 normal fetuses and 38 untreated or dexamethasone-treated fe... |
The core value of a quantum-key-distribution (QKD) system is the unconditional security. In the standard security analysis, the characteristics of QKD source are assumed to be known and fixed. In a real QKD experiment, this assumption may be deviated. Especially, in commercial Plug&Play QKD system, the source is untrus... |
Inhibition of factor Xa (FXa) may interrupt thrombus progression. This study compared the antithrombotic activity of a novel FXa inhibitor, ZK-807834 [MW, 527 D; Ki (human FXa), 0.11 nM], with recombinant tick anticoagulant peptide [rTAP; MW, 6,685 D; Ki, (human FXa) = 0.28 nM], and DX-9065a [MW 445 D, Ki (human FXa), ... |
In practice,it's feasible to achieve the integration of Shanghai cooperative organization and East Asia.The trend of this integration lies on two aspects: China is a participant of regionalization,and there are many interdependent conditions and the objective reality of the mutual needs and dependence in the two region... |
The paper introduced the use of a hybrid system of neural networks support vector machines (NNSVMs) consisting of artificial neural networks (ANNs) and support vector machines (SVMs) to price single-family properties.,The mechanism of the hybrid system is such that its output is given by the SVMs which utilise the resu... |
Understanding how DNA molecules interact with other biomolecules is related to how they utilize their functions and is therefore critical for understanding their structure-function relationships. For a long time, the existence of Z-form DNA (a left-handed double helical version of DNA, instead of the common right-hande... |
Mapping and sampling of 18 eruptive units in two study areas along the Galápagos Spreading Center (GSC) provide insight into how magma supply affects mid‐ocean ridge (MOR) volcanic eruptions. The two study areas have similar spreading rates (53 versus 55 mm/yr), but differ by 30% in the time‐averaged rate of magma supp... |
A combined binary PPM/orthogonal modulation is used in cellular CDMA reverse links in which the multipath-diversity performance for Rayleigh-fading channels is evaluated and compared. As for diversity techniques, equal gain combining (EGC), selection combining (SC), and its generalization, second or third order SC (SC2... |
A step-by-step deployment of work on the creation of a national geospatial data infrastructure within the digital development of Ukraine is considered. The goals of mentioned infrastructure are as follows: provision of the open access to data, in particular the data and knowledge of scientific researches and observatio... |
The digital industry of oceanographic geospatial data is expected to become one of the components of the national digital geospatial data infrastructure. It will primarily cover the oceanography, considering the scale and complexity of hydrophysical processes in the oceans, the multifaceted impact and use of data for t... |
The article presents an analysis of the Law on the National Infrastructure of Geospatial Data regarding the provisions that have to be fulfilled by the holders of oceanographic data. |
Considering that in accordance to the Law the national geospatial data infrastructure does not cover the entire array of collected oceanographic data, additional preparatory measures are proposed for the formation of a modern infrastructure and digital industry of oceanographic data. |
Creation of a modern digital industry of oceanographic data requires concerted efforts and consolidated actions of the state, scientific community, business entities and interested civil society. Its creation will ensure an appropriate level of participation and form a positive image of Ukraine in the framework of the ... |
To cite this article: Vijverberg SJH, Koster ES, Koenderman L, Arets HGM, van der Ent CK, Postma DS, Koppelman GH, Raaijmakers JAM, Maitland‐van der Zee A‐H. Exhaled NO is a poor marker of asthma control in children with a reported use of asthma medication: a pharmacy‐based study. Pediatr Allergy Immunol 2012: 23: 529–... |
BACKGROUND |
There is a need to specify the profile of subjective cognitive decline in preclinical Alzheimer's disease (preAD). |
OBJECTIVES |
To explore specific items of the Subjective Cognitive Decline Questionnaire (SCD-Q) that discriminate preAD from normal aging. |
METHODS |
68 cognitively normal older adults were classified as controls (n = 52) or preAD (n = 16) according to amyloid-β (Aβ) levels. An exploratory factor analysis and item analysis of the SCD-Q were performed. Informant reports of the SCD-Q were used to corroborate the findings of self-reports. One-year neuropsychological fo... |
RESULTS |
Four SCD-Q factors were extracted: EM-factor (episodic memory), A-factor (attention), O-factor (organization), and L-factor (language). PreAD reported a significantly higher decline in L-factor (F(1) = 6.49; p = 0.014) and A-factor (F(1) = 4.04; p = 0.049) compared to controls, and showed a higher frequency of perceive... |
CONCLUSIONS |
Our results suggest that SCD-Q items related with language and executive decline may help in prediction algorithms to detect preAD. Validation in an independent population is needed.Learning to Play Using Low-Complexity Rule-Based Policies: Illustrations through Ms. Pac-Man |
In this article we propose a method that can deal with certain combinatorial reinforcement learning tasks. We demonstrate the approach in the popular Ms. Pac-Man game. We define a set of high-level observation and action modules, from which rule-based policies are constructed automatically. In these policies, actions a... |
The paper is provoked by the rejection and falsification of the messages of the Istanbul Convention in Bulgaria and other post-communist countries which caused a wave of homophobia. The author tries to prove that neither in the communist period nor in the post-communist period a real emancipation of women was achieved,... |
During the communist period, the so called “Unions of the fighters against fascism” turned into the male clientelistic networks granted with many privileges and marginalizing female antifascists. The critical discourse analysis of the press (1976) reveals male dominance and silencing of women playing mostly a decorativ... |
The second part of the paper is a gender analysis of the lexical and grammatical system of the Bulgarian language. The analysis of the dominating metaphors reveals the means of male dominance in the everyday speech. Although the Slav languages have morphemes to denote women’s professions the media discourse prefers the... |
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