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15‐Lipoxygenase (15‐LO) has been implicated in oxidation of low‐density lipoproteins (LDL), a process believed to be important for the development of atherosclerosis, as well as other pathogenic conditions. Potent and selective inhibitors of 15‐LO may have a drug potential. In this study, purines with a variety of subs... |
Rock properties, which are rigidity and energy loss, can be estimated from the attenuation of acoustic waves (Q) or the velocity of propagation. Many velocity estimation studies have been done, by the pulse transmission method (eg. JGS2110-1998) and the frequency modulated continuous wave transmission method (eg. ACROS... |
ABSTRACT This article addresses the implications of researcher-student cooperation in the production of empirical material. For the student to replace the experienced researcher and work under the researcher’s supervision, we call such work proxy-produced ethnographic work. Although there are clear advantages, the spec... |
Contents: Introduction: Succession Problems and Challenges (J Wong & Y-N Zheng) The Politics of Succession: Previous Patterns and a New Process (F C Teiwes) Crossing the Political Minefields of Succession: From Jiang Zemin to Hu Jintao (S-P Zheng) Technocratic Leadership, Private Entrepreneurship, and Party Transformat... |
Over the period 2004–2007, the final energy consumption in the European Union 27 Member States (EU-27) decreased, while electricity end-use consumption in the EU-27 continued to grow, but at a lower rate than the economic growth. The final electricity consumption in the EU-27 Member States has continued to grow in the ... |
In this paper, we present fast neighbor join and fast link breakage detection schemes to enhance the minimal expected transmission (METX)-based routing scheme reported recently (Woo et al. (2003)). Current METX-based routing scheme uses a link estimator named window mean with exponential weighted moving average (WMEWMA... |
Abstract The 2005 Paris Declaration committed donors to increased use of recipient country systems for managing aid, particularly in countries with higher-quality systems. Using indicators explicitly endorsed by the Paris Declaration and covering the 2005-2010 period, this study finds a positive, significant, and robus... |
Abstract Drawing on theories of family language policy and literacy environment, this inquiry explores and describes how family language policy is managed through literacy resources and literacy related activities in transnational families in the UK. A total of 66 families, each with at least one child between the age ... |
We present an adaptive asymmetric diamond search (AADS) for block based motion estimation. The proposed method exploits an adaptive search pattern based on the predicted motion vector. In addition, the accuracy of the prediction is improved by changing the initial search center position. Simulation results show that th... |
High blood pressure (BP) is the most common cardiovascular risk factor worldwide and a major contributor to heart disease and stroke. We previously discovered a BP-associated missense SNP (single nucleotide polymorphism)–rs2272996–in the gene encoding vanin-1, a glycosylphosphatidylinositol (GPI)-anchored membrane pant... |
Prostacyclin was examined for its inhibitory effects on the tumor cell-induced platelet release reaction. Prostacyclin inhibited in a dose-dependent manner tumor cell-induced release of platelet dense granules and alpha-granules concomitant with an inhibition of platelet aggregation. Release was determined by assay of ... |
Explosive growth of biomedical data in various platforms presents a major challenge for bioinformatics research. To analyze the ever-increasing amount of data, it requires unprecedented storage resources and computing power. To maximize the limited resources for big data, we propose a model on Bioinformatics Problem So... |
ABSTRACT Agricultural workers have physically demanding occupations. In this study of Saskatchewan farmers, the authors examined (1) self-reported prevalence of physician-diagnosed rheumatoid arthritis and osteoarthritis; and (2) the impact of these chronic arthridities on engagement in physical tasks related to farmin... |
The purpose of this paper is to provide an in-depth analysis of computer aided system for the early diagnosis of Deep Vein Thrombosis (DVT). Normally, patients are diagnosed with DVT through ultrasound examination after they have a serious complication. Thus, this study proposes a new approach to reduce the risk of rec... |
AIMS |
The use of primary hepatocytes in pharmacological and toxicological research as well as for clinical and biotechnological applications requires adequate storage options for these cells. However, hepatocytes are very susceptible to cryopreservation injury. Based on experience in hypothermic storage of hepatocytes, we, i... |
MATERIALS AND METHODS |
Rat hepatocytes were cryopreserved in serum-containing cell culture medium or in serum-free solutions optimized for hypothermic storage, all with 10% dimethyl sulfoxide, using a standard protocol (-1°C/min in a controlled-rate freezer). After rapid thawing, cells were seeded in supplemented Leibovitz-15 cell culture me... |
RESULTS |
Cell attachment (37% ± 15% vs. 9% ± 7% of noncryopreserved control cells) and metabolic activity (resazurin reduction: 47% ± 23% vs. 25% ± 8%; glucose release: 44% ± 6% vs. 15% ± 7%; and urea production: 31% ± 16% vs. 5% ± 8%) were significantly higher after cryopreservation in the new solution compared to cryopreserva... |
CONCLUSIONS |
In summary, significant improvement of cell attachment and function compared to cell culture medium was achieved after cryopreservation in serum-free hepatocyte cold storage solution.Risk factors associated with the recall of respiratory diseases in the Ecuadorian children. |
Risk factors associated with the recall of a recent episode of acute respiratory infection (ARI) were evaluated in 1,553 Ecuadorian preschool children enrolled into a cross-sectional health and nutrition survey. In a univariate analysis, ARI recall was significantly higher in children living in low altitude regions (Re... |
Under uniform circular array, by employing some algebraic schemes to exploit the phase information of receiving data and further estimate the source’s three-dimensional (3D) parameters (azimuth angle, elevation angle, and range), a series of novel phase-based algorithms with low computational complexity have been propo... |
The information on transition of a thing is important for acquiring knowledge on the thing. In this study, we extracted transition information from a large number of sentences using pattern-based methods. We obtained an F-measure of 0.86 for extraction of transition information by this method. In order to improve the r... |
Abstract About 60 million children under the age of 18 are left behind by their parents in rural China. This paper studies the effect of migrant parents on the educational attainment of their left-behind children in rural China. A theoretical model of optimal schooling in the context of parental migration is proposed. ... |
Model transformation programs are iteratively refined, restructured, and evolved due to many reasons such as fixing bugs and adapting existing transformation rules to new metamodels version. Thus, modular design is a desirable property for model transformations as it can significantly improve their evolution, comprehen... |
1. Studies examining changes in the scheduling of breeding in response to climate change have focused on species with well-defined breeding seasons. Species exhibiting year-round breeding have received little attention and the magnitudes of any responses are unknown. 2. We investigated phenological data for an enclosed... |
tions for modelling the foot-shoe interface. Kelly et al. (2016) reported that the intrinsic foot muscles have the ability to regulate arch stiffness. These authors also proposed a theoretical model for the foot-shoe interface, in which the arch and the shoe act as two springs in series. With this model, an increase in... |
The level of ascorbic acid in the blood plasma of 59 calves was determined. The age of the calves ranged between two and three months and the samples of blood were collected in January. The first group of calves included 30 animals displaying no clinical symptoms of disease: the average ascorbic acid level was 0.50 +/-... |
Many techniques for power reduction in advanced RTL synthesis tools rely explicitly or implicitly on observability don’t-care conditions. In this article we propose a systematic approach to maximize the effectiveness of these techniques by generating power-friendly RTL descriptions in behavioral synthesis. This is done... |
We first introduce the concept of behavior-level observability and its approximations in the context of behavioral synthesis. We then propose an efficient procedure to compute an approximated behavior-level observability of every operation in a dataflow graph. Unlike previous techniques which work at the bit level in ... |
Abstract : The α subunits of Shaker‐related K+ channels (Kv1.X) show characteristic distributions in mammalian brain and restricted coassembly. Despite the functional importance of these voltage‐sensitive K+ channels and involvement in a number of diseases, little progress has been achieved in deciphering the subunit c... |
The probability of detection and the accuracy of a measurement are determined by the available SNR ratio and hence by the energy used for illuminating the target. Also, increasing the rate of illumination of a target allows obtaining less uncertain predictions. A high energy burst and a high illumination rate are desir... |
Metabolic syndrome (MetS) refers to a constellation of risk factors that include insulin resistance, abdominal obesity, hyperglycemia, hypertension and dyslipidemia. Atherosclerotic complications are the leading cause of increased morbidity and mortality in MetS. Individuals with MetS have an increased propensity for a... |
Société canadienne de météorologie et d'océanographie Introduction Among the extreme weather events of summer 2010, the extensive floods in Pakistan and their widespread impacts garnered maximum attention in the media as well as in the scientific community. Several climate scientists expressed concern about such weathe... |
This study uses two popular technical trading rules to assess whether the gradual liberalization of Taiwan's securities markets has improved the efficiency of its stock market. The results show that the two rules have considerable predictive power for 1983–1990, they become less predictive for 1991–1997, and they canno... |
The sequence kernel association test (SKAT) is widely used to test for associations between a phenotype and a set of genetic variants that are usually rare. Evaluating tail probabilities or quantiles of the null distribution for SKAT requires computing the eigenvalues of a matrix related to the genotype covariance betw... |
Childhood skin infections are commonly seen in both primary care and dermatology practice worldwide. They consume considerable resources and need careful management. However, education and reassurance of patients and parents, combined with simple treatment and self management, play a vital part in successful treatment.... |
We searched Medline, Embase, and the Cochrane Library by using the terms “scabies,” “head lice,” “folliculitis,” and “herpes simplex virus.” We included randomised trials, reviews, meta-analyses, and guidelines. |
Scabies is an intensely itchy dermatosis caused by the mite Sarcoptes scabiei . The infestation can occur at all ages but particularly occurs in children. It is a common public health problem in poor communities and developing countries. |
Scabies is highly contagious and is spread from person to person by direct skin contact. Transfer from clothes and bedding occurs rarely and only if contaminated by infectious people immediately beforehand.2 Infestation occurs when pregnant female mites burrow into the skin and lay eggs. After two or three days the lar... |
The main symptoms of scabies are caused by the host immune reaction to burrowed mites and their products.3 Symptoms appear within two to six weeks of the initial infestation, but reinfestation can provoke symptoms within 48 hours. The most common presenting lesions are papules, vesicles, pustules, and nodules. The path... |
Interest in hydrogen (H2) energy has exploded in the last few years. Much of the interest comes from transitioning to a decarbonised energy future, through the use of renewables, to convert hydrogen-rich materials (methane, water) to pure hydrogen gas streams. Each of these methods have their own challenges, such as th... |
Locating hotspots in metal engine components can be used as an impetus to design a better cooling system. This study focuses on a numerical investigation of a three-dimensional (3-D) transient heat transfer process for a Ford 5.4-L V8 engine. A 3-D transient finite-volume method to solve the heat conduction equation is... |
The results are reported of velocity measurements in oscillatory flow over rippled beds. Velocities were measured with a laser-doppler anemometer in both an oscillating tray rig and an oscillatory flow water channel. Both self-formed and artificial ripples were examined. In addition, some measurements were made with an... |
PURPOSE |
To compare the safety and efficacy of the fixed combination product with nonfixedcombination use of the same active ingredients in separate bottles (bimatoprost oncedaily[qd], and timolol twice-daily [bid]). A bimatoprost 0.03% qd treatment arm was usedfor validation of the study. |
METHODS |
This was a double-masked, randomized, parallel study in 445 patients with openangleglaucoma or ocular hypertension. They were randomized in a ratio of 2:2:1 to receivebilateral treatment with the fixed combination, non-fixed combination treatment, or bimatoprostalone. |
RESULTS |
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