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Answer the following medical question with the correct option:
The major limitation in the use of clozapine for treatment of schizophrenia is A) Its potential to cause agranulocytosis B) High incidence of extrapyramidal side effects C) Production of hyperprolactinemia D) Its inability to benefit negative symptoms of schizophrenia
A) Its potential to cause agranulocytosis
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Which is bilateral tumour:- A) Dysgerminoma B) Immatureteratoma C) Endodermal sinus tumur D) Embryonal cell carcinoma
A) Dysgerminoma
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A 65 year old retired accountant with a 60 pack year smoking history presents for his annual physical examination. He was last seen 3 years ago, when he presented with an episode of acute bronchitis. He repos that he has been coughing over the past several months with productive green sputum. He denies any dyspnea or l...
B) A hemoglobin of 17 g/dL
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Pramipexole is A) Dopamine agonist B) Antimalarial C) MAO-inhibitor D) Dopamine antagonist
A) Dopamine agonist
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Skin biopsy of a patient shows evidence of malignant melanoma. Which is the common type of malignant melanoma? A) Superficial spreading B) Lentigo maligna melanoma C) Nodular D) Acral lentiginous
A) Superficial spreading
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In a case of meningitis, Neisseria meningitides was grown in culture after 48 hours. Which measure is to be taken immediately? A) Isolation of contacts B) Antibiotic treatment of contacts C) Vaccination of contact D) All of the above
B) Antibiotic treatment of contacts
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Which of the following is not a pa of Kubler Ross Stages of impending death? A) Depression B) Bargain C) Aggression D) Anger
C) Aggression
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Hand wrist radiograph provides a view of: A) 25 bones B) 26 bones C) 30 bones D) 32 bones
C) 30 bones
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A 3 month old child presents with intermittent stridor. Most likely cause is - A) Laryngotracheobronchitis B) Laryngomalacia C) Respiratory obstruction D) Foreign body aspiration
B) Laryngomalacia
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True regarding perineal body are all except A) Perineal body intervenes between posterior vaginal wall and anal canal B) Bulbocavernosus converges on it superficially C) Pubococcygeus forms deeper relation D) External anal sphincter lies in deep relation with respect to perineal body.
D) External anal sphincter lies in deep relation with respect to perineal body.
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Prognosis in a soft tissue tumour is determined by - A) Grade of tumour B) Bulk of the tumour C) Depth of Invason D) Lymph nodal involvement
A) Grade of tumour
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Todd's palsy can occur affer episode of- A) Generalized tonic-clonic seizures B) Paial motor seizures C) Atonic seizures D) Myoclonic seizures
B) Paial motor seizures
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Length of anal canal A) 10 - 15 mm B) 15 - 20 mm C) 25 - 30 mm D) 35 - 40 mm
D) 35 - 40 mm
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Tension pneumothorax due to fracture rib is treated by: A) Strapping B) Tube drainage C) IPPV D) Internal fixation with open reduction
B) Tube drainage
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Which of the following is not a glycoprotein hormone: A) TSH B) FSH C) LH D) ACTH
D) ACTH
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Gout is a metabolic disorder of A) Purine B) Pyramidine C) Glycogen D) Fatty acid oxidation
A) Purine
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Phase 3 clinical trial is also called as A) Human pharmacology B) Post marketing surveillance C) Therapeutic exploration D) Therapeutic confirmation
D) Therapeutic confirmation
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Which of the following is the most common initial site of metastasis from a primary BCC? A) Lungs B) Regional lymph nodes C) Bone D) Liver
B) Regional lymph nodes
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Which of the following drug increases gastro -intestinal motility A) Glycopyrrolate B) Atropine C) Neostigmine D) Fentanyl
C) Neostigmine
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Bull's eye lesion in the macula is seen in: A) Chloroquine B) Hydroxychloroquine C) Quinine D) Sulfamethoxazole
A) Chloroquine
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Jeep&;s disease is A) Anal incontinence B) Haemorrhoids C) Pilonidal sinus D) Anal fissure
C) Pilonidal sinus
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Gettlers test is positive in - A) Hanging B) Drowning C) Strangulation D) Firearm injury
B) Drowning
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Persistent organ failure in the setting of acute pancreatitis is defined, when the organ failure lasts for more than: A) 12 hours B) 24 hours C) 48 hours D) 72 hours
C) 48 hours
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A girl child with verrucous lesions at an age of 2 weeks later on developed linear bands of hyperkeratotic papules and nodules followed by whorled pigmentation. Her mother had history of in utero child death and hypopigmented atrophic linear lesions. The diagnosis is A) Neurofibromatosis B) Xeroderma pirmentosa C) Tub...
D) Incontinentia pigmenti
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Normal adult haemoglobin contains A) One alpha chain and one beta chain B) One alpha chains and two beta chains C) One beta chains and two alpha chains D) Two alpha chains and two beta chains
D) Two alpha chains and two beta chains
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Lethargic hypoglycemic girl neonate with following genital appearance: A) Congenital adrenal hyperplasia B) Ovo-testicular disorder of sexual differentiation C) Turner syndrome D) Klinefelter syndrome
A) Congenital adrenal hyperplasia
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The most preferred approach for pituitary surgery at the present time is A) Transcranial B) Transethmoidal C) Transphenoidal D) Transcallosal
C) Transphenoidal
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A 33-year-old woman was evaluated for symptoms of severe intense generalized pruritus. Her physical examination reveals multiple sites of excoriation. Laboratory investigations confirm the clinical diagnosis of primary biliary cirrhosis (PBC). She is now inquiring about available treatments for this condition, includin...
D) liver transplantation
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Which of the following would MOST likely be found in the Congo red-stained extracellular deposits with the bright green appearance under polarized light? A) Amyloid AA B) Beta-2-microglobulin C) Beta protein precursor D) Immunoglobulin light chains
D) Immunoglobulin light chains
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Restoration commonly recommended for cervical abrasion is A) Silicate B) Polycarboxylate C) Glass ionomer D) Composites
C) Glass ionomer
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Hirano bodies are seen in : A) Parkinsonism B) Frontotemporal dementia C) Lewy body D) Alzheimer's disease
D) Alzheimer's disease
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Most consistent finding in acute viral hepatitis in CT is? A) GB wall thickening B) Periportal edema C) Lymphadenopathy D) Steatosis
B) Periportal edema
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The most common association with coarse pitting of nails and onycholysis is: A) Cicatricial alopecia B) Well defined scaly plaques C) Polygonal papule D) Violaceous papules
B) Well defined scaly plaques
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Kennedy class II condition derives its A) Primary support from the tissue underlying the base and secondary support from the abutment teeth. B) Primary support from the abutment teeth. C) Primary support from the tissue underlying the base. D) Primary support from the abutment teeth and secondary support from the tiss...
A) Primary support from the tissue underlying the base and secondary support from the abutment teeth.
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All the following are increased in pregnancy except: A) Blood volume B) GFR C) Renal plasma flow D) Plasma osmolality
D) Plasma osmolality
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Nil per oral orders for an 8 year old child posted for elective nasal polyp surgery at 8 AM is all except A) Milk can be taken at 7 AM in morning B) Apple juice can be taken at 10 PM previous night C) Rice can be consumed at 11 PM previous night D) Can take sips of water up to 6 AM in morning
A) Milk can be taken at 7 AM in morning
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Following are the ocular association of retinitis pigmentosa except: A) Myopia B) Primary angle closure glaucoma C) Microphthalmos D) Conical cornea
B) Primary angle closure glaucoma
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Recommended drug for patients with intrahepatic Wilson's disease i.e. patients with hepatitis, is A) Zinc B) Triamterene C) Trientine D) Penicillamine
A) Zinc
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Commonest cause of bronchiolitis: A) RSV B) Entero virus C) Pneumococcus D) Hemophilus
A) RSV
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Staphylococcus differes from streptococcus by ? A) Coagulase test B) Catalase test C) Phasphatase D) Gram negative
B) Catalase test
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Section 53 CrPC is- A) Kidnapping B) An accused can be examined by a medical practitioner at request of police, even without his consent or by force C) Toure D) Perjury
B) An accused can be examined by a medical practitioner at request of police, even without his consent or by force
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The most common type of emphysema associated with alpha-1 antitrypsin deficiency? A) Centraacinar B) Panlobular C) Panacinar D) Irregular
C) Panacinar
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True statement about streptococcus faecalis is A) Growns in 6.5% Nacl solution B) Are lactose fermenter C) Easily destroyed at 60 o C for 30 minutes D) Classified on the basis of teichoic acid of cell wall
A) Growns in 6.5% Nacl solution
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All of the following are features of pheochromocytoma except- A) Hypeensive paraoxysm B) Headache C) Ohostatic hypotension D) Wheezing
D) Wheezing
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The major venous return of the hea, the coronary sinus, empties into A) IVC B) Left atrium C) Right atrium D) Right ventricle
C) Right atrium
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Which is the most common nephropathy associated with malignancy? A) Membranous B) MCD C) IgA D) FSGS
A) Membranous
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Which of the following has least minimum infective dose(MID) required for causing infection: A) Salmonella typhi B) Campylobacter jejuni C) Shigella dysentery D) Vibrio cholera
C) Shigella dysentery
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Guillain-Barre' syndrome (GBS) commonly associated with A) Japanese encephalitis virus B) Campylobacter C) Meningococcus D) Acanthoemeba
B) Campylobacter
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A 30-year-old multiparous female complains of a painless ulcer in vulva. She has several sexual partners. Her previous pregnancy has ended in a still birth at 24 weeks. What is the first test, which should be performed in this case: A) ELISA for HIV B) VDRL Test C) Culture of scraping from the ulcer D) Election micros...
B) VDRL Test
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The primary action of Nitric oxide (NO) in the gastrointestinal tract is - A) Vasodilatation B) Vasoconstriction C) Gastrointestinal smooth muscle relaxation D) Gastrointestinal slow smooth muscle contraction
C) Gastrointestinal smooth muscle relaxation
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Rotational changes in the mandible essentially consist of A) Matrix rotation 25% and Intramatrix rotation 75% B) Matrix rotation 50% and Intramatrix rotation 50% C) Matrix rotation 100% and Intramatrix rotation 0% D) Matrix rotation 0% and Intramatrix rotation 100%
A) Matrix rotation 25% and Intramatrix rotation 75%
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Which of the following is a mood stabilizer? A) Lithium B) Haloperidol C) Amitriptyline D) Diazepam
A) Lithium
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A female comes in OPD with a breast lump. After careful history and examination, breast biopsy is suggested by a senior resident doctor. Find out the TRUE statement about the surgical wound inflicted during the procedure: A) Expected infection rate in the wound is 10% B) Classified as clean/contaminated wound (class I...
C) No Prophylactic antibiotics need to be given to the patient
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Bezold abscess is located in - A) Submandibular region B) Sternocleidomastoid muscle C) Diagastric triangle D) Infratemporal region
B) Sternocleidomastoid muscle
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Niemann - Pick disease is due to deficiency of which of the following enzymes? A) Acid Sphingomyelinase B) Hexosaminidase A C) Ceramidase D) Arylsulfatase B
A) Acid Sphingomyelinase
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The prostatic urethra is characterized by all of the following features, except A) Is the widest and most dilatable pa B) Presents a concavity posteriorly C) Lies closer to anterior surface of prostate D) Receives prostatic ductules along its posterior wall
B) Presents a concavity posteriorly
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Nonprogressive contraction of esophagus are: A) Primary B) Secondary C) Tertiary D) Quaternary
C) Tertiary
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Chediak Higashi disease is characterized by the following except? A) Neutrophilia B) Defective degranulation C) Delayed microbial killing D) Giant granules
A) Neutrophilia
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Following genetic counselling in a family for Familial polyposis coli (FPC) next screening test is A) Flexible sigmoidoscopy B) Colonoscopy C) Occult blood in stools D) APC gene
D) APC gene
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Hurthle cells are characteristically seen in which of the following thyroid disease? A) Hashimoto's thyroiditis B) Graves' disease C) de Quervain's thyroiditis D) Subacute lymphocytic
A) Hashimoto's thyroiditis
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Waterfall effect is seen in: A) Apex of lung B) Mid lung C) Base D) Throughout the lung
B) Mid lung
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A condon consists of - A) Two complementary base pairs B) Three consecutive nucleotide units C) An individual ribosome D) Four individual nucleotides
B) Three consecutive nucleotide units
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Which of the following is the causative agent of STD disease donovanosis? A) Hemophilus ducrevi B) Klebsiella granulomatis C) Leishmania donovani D) Treponema pallidum
B) Klebsiella granulomatis
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Which of the following is not a type of balance in complete denture occlusion. A) Bilateral lever balance B) Unilateral occlusal balance C) Bilateral occlusal balance D) Protrusive occlusal balance
A) Bilateral lever balance
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Products of Phospholipase C are - A) Inositol and diacylglycerol B) Inositol triphosphate and Diacylglycerol C) Lysophospholipid and fattyacid D) Phosphatidate and IP2
B) Inositol triphosphate and Diacylglycerol
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Using a small fine probe, single lactiferous duct is excised. What is the name of the procedure: A) Macrodochectomy B) Microdochectomy C) Webster operation D) Hadfield operation
B) Microdochectomy
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Wof gland is impacted in Fox Fordyce disease A) Sebaceous glands B) Eccrine glands C) Pilosebaceous units D) Apocrine glands
D) Apocrine glands
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Leptospirosis, all are true except A) Faeces & urine of rodents is the cause B) onset of IgM in 2 days C) Incubation period is 10 days D) It is sensitive to penicillin
B) onset of IgM in 2 days
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A 75-year-old woman with rheumatoid arthritis (RA) takes aspirin for symptom control. She usually adjusts the dose of her own medications depending on how she is feeling.For the above patient with a toxic ingestion or exposure, select the most likely clinical effect. A) combines with cytochromes and catalase to block ...
C) vertigo, hyperventilation, tinnitus, and deafness
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The etiologic factor implicated in the development of pulmonary insufficiency following major nonthoracic trauma is A) Aspiration B) Atelectasis C) Fat embolism syndrome D) Fluid overload
C) Fat embolism syndrome
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What is the cause of tetany in patients with hyperventillation ? A) Metabolic alkalosis B) Decreased levels of potassium C) Respiratory acidosis D) Decreased plasma calcium levels
D) Decreased plasma calcium levels
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In IgA nephropathy (Berger's disease), there are ? A) Subepithelial deposits B) Subendothel i al deposits C) Mesangial deposits D) Basement membrane deposits
C) Mesangial deposits
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Gray hepatization of lungs is seen on day: A) 1 B) 3-Feb C) 5-Mar D) 7-May
C) 5-Mar
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All of the following acute myeloid leukaemia are diagnosed regardless of blast count Except A) AML with t(8;21) B) AML with t(15;17) C) AML with t(16;16) D) AML with t(1;9)
D) AML with t(1;9)
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Virulence or pathogenicity of pneumococcus depends upon- A) Capsular polysaccharide B) Cell wall antigen C) Flagellar antigen D) Fimbrial antigen
A) Capsular polysaccharide
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The proportional mortality rate is A) Number of death during that year B) Number of death in one month C) Number of death due to particular a cause D) None
C) Number of death due to particular a cause
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Medullary carcinoma thyroid arises from ? A) Parafollicular cells B) Cells lining the acini C) Capsule of thyroid D) Stroma of the gland
A) Parafollicular cells
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Nohern blotting is used for analysis of A) DNA B) RNA C) Proteins D) Polysaccharides
B) RNA
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Total skin electron irradiation is used for of A) Sezary syndrome B) Mycoses fungoides C) Psoriasis D) Brain metastasis of skin cancer
B) Mycoses fungoides
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Salk polio vaccine is ? A) Killed B) Live attenuated C) Subunit D) Recombinant
A) Killed
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Chorioretinitis is caused by - A) Toxoplasmosis B) CMV C) Rubella D) Oncocerca volvulus
A) Toxoplasmosis
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Right lung is seen to best advantage on the following views: A) Right posterior oblique B) Right anterior oblique C) Left anterior oblique D) Lateral
C) Left anterior oblique
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Number of permanent teeth in a 8 year old child A) 4 B) 8 C) 12 D) 20
C) 12
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Most sensitive diagnostic test for ectopic pregnancy: A) Transvaginal USG B) Serial monitoring of beta HCG C) Culdocentesis D) MRI
A) Transvaginal USG
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All is true about Giant cell aeritis except ? A) Involves large to small sized areteries B) Granulomatous inflammation C) Most commonly involved aery is abdominal aoa D) Segmental nature of the involvement
C) Most commonly involved aery is abdominal aoa
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The specific gravity of a transudate is: A) Below 1.010 B) Below 1.012 C) Between 1.012 and 1.020 D) Above 1.020
B) Below 1.012
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The enamel bevel of a gingival floor is done with: A) Hatchet B) Chisel C) Hoe D) Curette
B) Chisel
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True about CPAP all except aEUR' A) Used prophylactically in baby born with < lkg wt or < 28 weeks gestation B) Initiate as early in preterm with resp. distress C) Initiate with < 50 - 60 % Fi02 D) Improved lung compliance and oxygenation
A) Used prophylactically in baby born with < lkg wt or < 28 weeks gestation
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Neostigmine antagonizes non-depolarizing blockade by all of the following mechanisms EXCEPT A) Decreasing the breakdown of acetylcholine at the motor end plate B) Preventing the K+ efflux from the cell C) Increasing the release of acetylcholine at the motor end plate D) Depolarization at the motor end plate
B) Preventing the K+ efflux from the cell
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All of the following are side effects of growth hormone (supplements) therapy except A) Slipped capital femoral epiphysis B) Gynaecomastia C) Hypoglycemia D) Pseudotumour cerebri
C) Hypoglycemia
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Arch of Aorta is derived from all except - A) Left horn of Aortic sac B) Left 4th arch artery C) Left dorsal aorta D) Left 2nd arch artery
D) Left 2nd arch artery
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A tableau was held in a village to educate the villagers about early detection of oral cancer. This type of health education is called: A) Symposium B) Seminar C) Role play D) Learning by doing
C) Role play
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Which of the following is treatment of choice for Wegener's granulomatosis: A) Antibiotics B) Steroids C) Analgesics D) Antiviral therapy
B) Steroids
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All are included in diagnostic criteria of somatization disorder except - A) Sexual symptom B) Pain symptom C) GI symptom D) Visual symptoms
D) Visual symptoms
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Stages of Anaesthesia were established by : A) Ether B) Nitrous Oxide C) Cyclopropane D) Chloroform
A) Ether
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A moribund patient who is not expected to survive without an operation is put under which category as per the ASA Physical status classification system? A) P2 B) P4 C) P5 D) P6
C) P5
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Which of the following is given as live oral vaccine ? A) B.C.G B) Measles C) Typhoid D) Rabies
C) Typhoid
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True about Stage III B Endometrial Carcinoma A) Vaginal metastasis B) Lymph node metastasis C) Bowel involvement D) Lung metastasis
A) Vaginal metastasis
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Food poisoning with incubation period of 1-6 hours is most probably caused by A) H. pylori B) Salmonella typhi C) Streptococcus viridans D) Staphylococcus aureus
D) Staphylococcus aureus
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Which is the most common inherited bleeding disorder? A) Von Wilebrand disease B) Bernard soulier C) Glanzmann Thrombasthenia D) ITP acute
A) Von Wilebrand disease