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Answer the following medical question with the correct option:
Krabbe’s disease caused by deficiency of A) Sphingo myelinase B) Alpha galactosidase C) Galacto cerebrosidase D) Aryl sulfatase A
C) Galacto cerebrosidase
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Beta agonist which is used for stopping premature labor is: A) Carvedilol B) Terbutaline C) Pindolol D) Nadolol
B) Terbutaline
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Which of the following lesions is NOT an infection from human papilloma virus? A) Verruca vulgaris B) Focal epithelial hyperplasia C) Condyloma acuminatum D) None of the above
D) None of the above
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Which of the following is a debranching enzyme: A) Glycogen synthetase B) Glucose-6-phosphatase C) Amylo alpha-1,6-glucosidase D) Amylo (1,4)-(1,6) trans glycosylase
C) Amylo alpha-1,6-glucosidase
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Which of the following synaptic transmitter is NOT a peptide, polypeptide or protein A) Substance P B) Met-enkephalin C) b-Endorphin D) Serotonin
D) Serotonin
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At which level of heat stress index it is not possible to work comfoably causing threat to health: A) 20-40 B) 40-60 C) 60-80 D) 80-100
B) 40-60
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Rosiglitazone mechanism of action is ? A) Acts as PPAR gamma agonist B) Inhibitor of alpha glucosidase C) Acts as amylin analogue D) Acts as dipeptidyl peptidase inhibitor
A) Acts as PPAR gamma agonist
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A person was brought by police from the railway platform. He is talking irrelevant. He is having dry mouth with hot skin, dilated pupils, staggering gait and slurred speech. The most probable diagnosis is: A) Alcohol intoxication B) Carbamates poisoning C) Organophosphorous poisoning D) Dhatura poisoning
D) Dhatura poisoning
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Which of the following layers of epidermis is known as "prickle layer"? A) Stratum basale B) Stratum spinosum C) Stratum granulosum D) Stratum corneum
B) Stratum spinosum
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Energy currency of the cell is A) Nucleotide diphosphate B) Nucleotide triphosphate C) Deoxynucleotide diphosphate D) Nuceotide monophosphate
B) Nucleotide triphosphate
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Commonest type of cong. cyanotic hea disease is A) ASD B) VSD C) TOF D) PDA
C) TOF
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CRF with anemia best treatment - A) Iron B) Erythropoietin C) Blood transfusion D) Folic acid
B) Erythropoietin
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A 32-year-old woman was admitted to the hospital with a complaint of pain over her umbilicus. Radiographic examination revealed acute appendicitis. The appendix was removed successfully in an emergency appendectomy. One week postoperatively the patient complained of paresthesia of the skin over the pubic region and the...
B) Ilioinguinal
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A 70–year–old man presents with deterioration of vision 3 weeks after cataract extraction and IOL implantation. Slit lamp examination shows honeycomb maculopathy and Fluorescein angiography (FA) shows 'flower petal' hyperfluorescence. The most likely diagnosis is – A) Age related macular degeneration (ARMD) B) Central...
D) Cystoid Macular Edema
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All of the following statements about Trientine are true, EXCEPT: A) More potent than penicillamine and orally absorbed B) Alternative to penicilliamine in non tolerant C) Not given with iron within two hours of ingestion D) May cause iron deficiency anemia
A) More potent than penicillamine and orally absorbed
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RET gene mutation is associated with which malignancy - A) Pheochromocytoma B) Medullary carcinoma thyroid C) Lymphoma D) Renal cell carcinoma
B) Medullary carcinoma thyroid
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Most reabsorption out of A) Glucose B) Urea C) Na+ D) HCO3
A) Glucose
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The tumour exclusively found in parotid gland: A) Wahin tumour B) Adenocarcinoma C) Pleomorphic adenoma D) Acinar cell tumour
A) Wahin tumour
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Which of the following finding on MR imaging distinguishes vaginal atresia from mullerian agenesis A) Amount of upper vaginal dilatation B) Presence of cervix C) Length of atresia D) Hymeneal ring
B) Presence of cervix
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A 40 year old female patient complains of swelling on both the legs. Patient is pregnant (3rd trimester). Which type of thrombosis is most likely to be present in this patient? A) Venous B) Arterial C) Mural D) Saddle
A) Venous
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Wire loop lesions are often characteristic for the following class of lupus nephritis: A) Mesangial proliferative glomerulonephritis(WHO class II) B) Focal proliferative glomerulonephritis (WHO class III) C) Diffuse proliferative glomerulonephritis (WHO class IV) D) Membranous glomerulonephritis (WHO class V)
C) Diffuse proliferative glomerulonephritis (WHO class IV)
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All are zoonotic disease EXCEPT A) Brucellosis B) Leptospirosis C) Scabies D) Rabies
C) Scabies
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Wasting of the intrinsic muscles of the hand can be expected to be due to injury which nerve ? A) Ulnar nerve B) Radial nerve C) Brachial nerve D) Axillary nerve
A) Ulnar nerve
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Which drug is used for Achalasia cardia- A) Nifedipine B) Propranolal C) Atenolol D) Bethnecol
A) Nifedipine
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Wilm's tumor is associated with all the following except : A) Aniridia B) Beckwith syndrome C) Polycystic kidney D) Hemi – hypertrohy
C) Polycystic kidney
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Which of the following conditions is associated with maximum hearing loss? A) Otitis media with effusion B) Paial fixation of the stapes footplate C) Ossicular disruption with intact tympanic membrane D) Disruption of malleus and incus as well tympanic membrane
C) Ossicular disruption with intact tympanic membrane
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Mucopolysaccharide hyaluronic acid is present in which among the following: A) Vitreous humor B) Cornea C) Blood vessels D) Lens
A) Vitreous humor
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The development of resistance to conventional treatment has led WHO to recommned the use of combination therapies containing aemisinin derivative (aemisinin-based combination therapies also known as ACTs). All of the following combination therapies are recommended if such resistance is suspected, except - A) Aemether ...
B) Aesunate plus quinine
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A 66-year-old man presents with a sudden onset of diabetes, anorexia, weight loss, epigastric pain with radiation to back. Next best investigation for this patient is? A) Ultrasound of abdomen B) CT abdomen C) Enteroclysis D) Triple contrast barium enema
B) CT abdomen
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3M-mix antibiotic paste includes the following as intracanal medicament A) Ciprofloxacin, Metronidazole, Minocycline B) Norfloxacin, Metronidazole, Minocycline C) Ciprofloxacin, Cefixime, Minocycline D) Norfloxacin, Metronidazole, Cefixime
A) Ciprofloxacin, Metronidazole, Minocycline
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The labiodental sounds are A) f,v,ph B) s,z,c C) f,z,s D) f,v,z
A) f,v,ph
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Kwashiorkor is similar to marasmus in that both diseases have __________ A) A normal total caloric intake B) A fatty liver C) An apathetic affect D) Anemia
D) Anemia
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RD k diagnosed by: A) +90 D B) Hurby lens C) 3 mirror contact lens D) All
D) All
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The process of primary colonizing bacteria adhering to tooth surface providing new receptors for attachment other bacteria is known as A) Attachment B) Translocation C) Co-adhesion D) Biofilm
C) Co-adhesion
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'Chancre redux' is a clinical feature of: A) Early relapsing syphilis B) Late syphilis C) Chancroid D) Recurrent herpes simplex infection
A) Early relapsing syphilis
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Gettlers test is for - A) Hanging B) Strangulation C) Bums D) Drowning
D) Drowning
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Which of the following organelles is the major site for anaerobic metabolism? A) Centrioles B) Mitochondria C) Golgi apparatus D) Cytoplasm
D) Cytoplasm
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Mc Naughten's rule : A) Section 84 B) Section 85 C) Section 86 D) Section 87
A) Section 84
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Soft water has hardness levels of - A) <50 B) 100 C) 150 D) >200
A) <50
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In Krebs cycle, which of the following catalyses the step in which the first CO2 is released? A) Aconitase B) Isocitrate dehydrogenase C) Succinate thiokinase D) Succinate dehydrogenase
B) Isocitrate dehydrogenase
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Which of the following variant of CAH presents with mineralocoicoid deficiency? A) 11b hydroxylase deficiency B) 17a hydroxylase deficiency C) P450 oxidoreductase dehydrogenase D) 3b hydroxyl-steroid dehydrogenase
D) 3b hydroxyl-steroid dehydrogenase
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Indicator used in autoclave is - A) Clostridium tetani B) Bacillus stearothermophilus C) Bacillus pumilis D) Bacillus subtilis Var Niger
B) Bacillus stearothermophilus
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All of the following are done in behavior therapy to increase a behavior except: A) Punishment B) Operant conditioning C) Negative reinforcement D) Reward
A) Punishment
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The cough response caused while cleaning the ear canal is mediated by stimulation of- A) The V cranial nerve B) Innervation of external ear canal by C1 and C2 C) The X cranial nerve D) Branches of the VII cranial nerve
C) The X cranial nerve
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O2 dissociation curve is shifted to right in all except- A) Hypercapnea B) Rise in temperature C) Raised 2, 3 DPG level D) Metabolic alkalosis
D) Metabolic alkalosis
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True about hepatitis A viurs ? A) Causes cirrhosis B) Helps HDV replication C) Common cause of hepatitis in children D) Causes chronic hepatitis
C) Common cause of hepatitis in children
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The following tests may be useful in the assessment of a patient with sarcoidosis A) Chest X-ray B) ACE C) Serum calcium D) All of the above
D) All of the above
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which of the following SSRI is hea safe A) escitalopram B) clomipramine C) fluoxetine D) amitriptilline
A) escitalopram
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Choose the appropriate lettered structure in this MRI scan showing a transaxial section through the head. Which structure may be obliterated by a pituitary tumor? A) A B) B C) C D) D
C) C
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Pedigree Chart - A) Used for growth monitoring. B) To assess side effect during chemotherapy C) Used to see genetic transmission. D) To assess developmental delay in infant
C) Used to see genetic transmission.
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True about cornea –a) Power is 43 Db) Majority of refraction occur at air – tear interfacec) With the rule astigmatism is present because vertical meridian more steep than horizontal meridiand) Spherical structuree) Refractive index 1.334 A) ab B) bc C) abc D) bcd
C) abc
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Following is/ are the clinical feature/ s of lepromatous leprosy - A) Leonine facies B) Loss of libido and impotence C) Saddle nose D) All the above
D) All the above
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Causes of macrocephaly includes? A) Galactosemia B) Weaver syndrome C) Soto's syndrome D) All of the above
D) All of the above
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The maximum dose of isotretinoin should not exceed A) 30-60mg/kg B) 60-90 mg/kg C) 90-120 mg/kg D) 120-150 mg/kg
D) 120-150 mg/kg
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Which of the following is feature of reticulocyte? A) Constitute 10% of the red cells B) No nucleus C) Smaller in the size than RBCs D) Mature in lymph nodes
B) No nucleus
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Nanotechnology has found tremendous application in the diagnosis of cancers because of all of following advantages, except A) Nanocrystals exibit bright, photostable fluorescence B) Nonocrystals have a narrow spectrum wavelength C) Peak spectrum wavelength is tunable D) Nanocrystals exhibit a narrow difference between...
D) Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra
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Complications of sphenoid sinus surgery are all except: A) CSF leak B) Optic nerve injury C) Lateral rectus palsy D) Orbital emphysema
D) Orbital emphysema
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Erosive ahritis is seen in all, except A) SLE B) Gout C) Osteoahritis D) Old age
A) SLE
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A 9 1/2 -year-old girl presents to your office with an approximately 1 1/4 -cm nodule in her neck, just to the left of the midline and below her cricoid cartilage. It is nontender and moves when she swallows. It has been enlarging over the last several months and was not seen by the pediatrician at her 9-year-old check...
B) Papillary thyroid cancer
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Site of transplantation in Islet cell transplant for Diabetes mellitus is A) Skin B) Injected into the poal vein C) Liver D) Pelvis
B) Injected into the poal vein
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A young pt presents with jaundice. Total bilirubin is 21, direct is 9.6, alkphosis 84 KA units. Diagnosis is: A) Hemolytic jaundice B) Viral hepatitis C) Chronic active hepatitis D) Obstructive jaundice
D) Obstructive jaundice
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A 20 year old man presents with swelling of left lower limb and hydrocoele. All of the following may be the causative agent EXCEPT: A) Brugia malayi B) Brugia timoria C) Wuchereria bancrofti D) Onchocerca volvulus
D) Onchocerca volvulus
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Very high intraocular pressure, veically oval mid-dilated pupil and shallow anterior chamber is seen in: A) Primary open angle glaucoma B) Acute primary angle closure glaucoma C) Malignant glaucoma D) Pupillary block glaucoma
B) Acute primary angle closure glaucoma
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Which of the following vaccines can be used in pregnancy in normal circumstances? A) MMR vaccine B) Varicella vaccine C) Influenza trivalent vaccine D) Hepatitis A vaccine
C) Influenza trivalent vaccine
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True statement about listeria: A) Gram negative bacillus B) Motile by peritrichous flagella C) Commonest cause of community acquired meningitis D) Only one serovar is known
B) Motile by peritrichous flagella
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Acute graft rejection occurs within? A) Few minutes B) Few hours C) < 6 months D) 6-12 months
C) < 6 months
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The protein that carries iron from the gut to the body tissues is called A) Ferritin B) Haemosiderin C) Myoglobin D) Transferrin
D) Transferrin
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After an endoscopy a technician kept the instrument for sterilization. Which of the following agent is used for sterilization of fibre optic instruments? A) Glutaraldehyde B) Chlorine C) Autoclave D) Phenol
A) Glutaraldehyde
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Cytokinee are secreted in sepsis in and systemic inflammatory response syndrome (SIRS) by: A) Neutrophils B) Adrenal C) Platelets D) Collecting duct
A) Neutrophils
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Necrotizing lymphadenitis is seen in: A) Kimura disease B) Kikuchi Fujimoto disease C) Hodgkin disease D) Castelman disease
B) Kikuchi Fujimoto disease
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Enucleation of the eyeball is contraindicated in A) Endophthalmities B) Panophthalmities C) Intraoccular tumours D) Painful blind eye
A) Endophthalmities
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Colostrums has in compared to normal milk - A) Decreased K B) Decreased Na C) Increased proteins D) Increased calories
C) Increased proteins
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The prognosis of rhabdomyosarcoma is likely to be poor if the site of the tumor is ? A) Orbit B) Paratesticular C) Extremity D) Urinary bladder
C) Extremity
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Pipkin classification is used for A) Acetabular fractures B) Pelvis ring fracture C) Femoral head fracture D) Femoral shaft fracture
C) Femoral head fracture
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Osteoarthritis does not affect: A) Knee joint B) Hip joint C) Interphalangial joint D) Metacarpophalangial joint
D) Metacarpophalangial joint
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Most common viral cause of acquired aqueductal stenosis is ? A) Rubella B) Mumps C) Toxoplasma D) Enterovirus
B) Mumps
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Pulsatile GnRH is used for managing: A) Precocious puberty B) Fibroid C) DUB D) Anovulatory infertility
D) Anovulatory infertility
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The regional aerial resistance of the mesentery and kidney vessels is reduced by A) Dopamine B) Dobutamine C) Nor adrenaline D) Isoprenaline
C) Nor adrenaline
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All true about pisiform, except Manipal 11 A) Last carpal bone to ossify B) Attached to flexor carpi ulnaris C) Can be seen on newborn X-ray D) It is a sesamoid bone
C) Can be seen on newborn X-ray
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Which of the following is an indication for using mifepristone? A) Ectopic pregnancy B) Fibroid uterus C) Molar pregnancy D) Habitual aboion
B) Fibroid uterus
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After passing his physical exam, a 19 year old army recruit gives urine and blood samples for fuher testing. Serum analysis yields elevated ALT, HBsAg, Anti-HBc, HBeAg, and bilirubin. All other values are normal. Which of the following is the hepatitis B status of this recruit? A) Asymptomatic carrier B) Chronic activ...
B) Chronic active carrier
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Which of the following organs does not show pale infarct? A) Lung B) Hea C) Kidney D) Spleen
A) Lung
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Mitochondrial chromosomal abnormality leads to A) Leber's hereditary optic neuropathy B) Angelman syndrome C) Prader villi syndrome D) Myotonic dystrophy
A) Leber's hereditary optic neuropathy
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Gestational sac is seen by TVS at- A) 5 weeks B) 6 weeks C) 7 weeks D) 8 weeks
A) 5 weeks
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Mechanism of action of transexaminic acid is? A) Decrease vascular permeability B) Smooth muscle contraction C) Activates Plasmin formation D) Prevents fibrinolysis
D) Prevents fibrinolysis
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Rotator interval is between: A) Supraspinatus and teres minor B) Teres major and teres minor C) Supraspinatus and subscapularis D) Subscapularis and infraspinatus
C) Supraspinatus and subscapularis
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Which of the following drug is used as a Transcranial patch for Parkinson's disease A) Levodopa B) Rotigotine C) Selegiline D) Carbidopa
B) Rotigotine
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The treatment of Acute Manic Episodes is A) ECT B) ECT C) Diazepam D) Sodium valproate
B) ECT
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In cochlear implants electrodes are most commonly placed at - A) Oval window B) Round window C) Horizontal semicircular canal D) Cochlea
B) Round window
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Hypersensitivity vasculitis is most commonly seen in: A) Post capillary venules B) Aerioles C) Veins D) Capillaries
A) Post capillary venules
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Hill Sach&;s lesion is most commonly seen in A) Recurrent shoulder dislocation B) Posterior shoulder dislocation C) Fracture neck of humerus D) Anterior shoulder dislocation
A) Recurrent shoulder dislocation
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Natural killer cell is - A) MHC restricted B) Antibody dependent C) Null cells D) B-lymphocytes
C) Null cells
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Radionucleide of choice for the assessment of renal function? A) MIBG B) DTPA C) Thallium D) Sulphur
B) DTPA
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Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone? A) Mefloquine B) Doxycycline C) Ataquinone/Proguanil D) Primaquine
A) Mefloquine
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Most common nerve injured in ligation of superior thyroid aery: A) Recurrent laryngeal nerve B) Facial nerve C) Mandibular nerve D) External laryngeal nerve
D) External laryngeal nerve
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Antiphospholipid syndrome ( APS) is associated with all of the following except: A) pancytopenia B) Recurrent aboions C) Venous thrombosis D) pulmonary hypeension
A) pancytopenia
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Duret hemorrhage seen in - A) Brain B) Kidney C) Heart D) Lung
A) Brain
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Which of the following is/are features of dishpan digit? A) Reddened finger B) Exceptionally clean thumb C) Fibrous rough callus D) All of the above
D) All of the above
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Age limit for HDI? A) 25 to 85 yrs B) 25 to 50 yrs C) 15 to 45 yrs D) 50 to 75 yrs
A) 25 to 85 yrs
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35-year-old woman presents to OPD with complains of headache after hitting her head accidentally with the wall while doing household chores . An MRI was ordered which confirmed presence of blood clot in the great cerebral vein of Galen. Obstructed vein is a direct tributary of which of the following venous structures? ...
D) Dural venous sinuses