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Answer the following medical question with the correct option:
Tumorogenesis in aging is due to - A) Telomerase reactivation B) Telomerase inactivation C) Increased apoptosis D) Suppression of proto-oncogenes
A) Telomerase reactivation
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All are true regarding typhoid ulcer EXCEPT: September 2012 A) Ileum is the common site B) Bleeding is common C) Stricture is usual and causes obstruction D) Perforation is common
C) Stricture is usual and causes obstruction
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All are true regarding paroxysmal nocturnal haemoglobinuria, except- A) Haemosiderinuria B) Pancytopenia C) Increased alkaline phosphatase D) Cellular marrow
C) Increased alkaline phosphatase
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The lesion listed below that would most likely pursue a benign course is :- A) Vaginal adenosis B) Adenomyosis C) Extramammary Paget's disease D) Endometrial hyperplasia
B) Adenomyosis
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Chromophobe variant of renal cell carcinoma is associated with - A) VHL gene mutations B) Trisomy of 7 and 17 (+7, +17) C) 3 p deletions (3p-) D) Monosomy of 1 and Y (-1, -Y)
D) Monosomy of 1 and Y (-1, -Y)
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Canakinumab is a monoclonal antibody against: A) IL-1 B) IL-2 C) IL-5 D) IL-6
A) IL-1
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Minimum amount of GI bleed to cause malena is A) 10 ml B) 40 ml C) 60 ml D) 115 ml
C) 60 ml
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Sympathetic innervation of heart is by - A) T1-T3 B) T1 - T5 C) c) T3-T7 D) L1 - L5
B) T1 - T5
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All of the following can induce methemoglobinemia EXCEPT: A) Nitroglycerine B) Procaine C) Prilocaine D) Phenytoin
D) Phenytoin
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Kamli Rani, 75-years -old woman present with post myocardial infarction after 6 weeks mild CHF. There was past H/O neck surgery for parathyroid adenoma 5 years ago, ECG shows slow atrial fibrillation. Serum Ca2+ 13.0 mg/L and urinary Ca2+ is 300 mg/24 hr. On examination there is small mass in the Para tracheal position...
D) Ultrasound-guided alcohol injection of the mass
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True regarding multiple myeloma is all, EXCEPT- A) Bone pain B) Lytic lesions C) Increased alkaline phosphatase D) Tarterate resistance, acid phosphatase positive
C) Increased alkaline phosphatase
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All are true for transplanted kidney except A) Humoral antibody responsible for rejection B) CMI is responsible for rejection C) Previous blood transfusion D) HLA identity similarity seen in 1:100 people
D) HLA identity similarity seen in 1:100 people
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Non-coding RNAs are A) siRNA B) miRNA C) tRNA D) mRNA
A) siRNA
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'Brush burns' are synonymous with A) Graze abrasion B) Scalds C) Electrical injury D) Injury by a brush
A) Graze abrasion
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Cervical cone biopsy in a case of carcinoma cervix causes all, except : A) Bleeding B) Cervical stenosis C) Infection D) Spread of malignancy
D) Spread of malignancy
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A 57-year-old man arrives at the emergency room complaining of weakness, fatigue, and intermittent fever that has recurred for several weeks. The patient had a cardiac valvular prosthesis implanted 5 years ago. Blood cultures grew ceain gram-positive cocci on which catalase and coagulase test were done. The gram-positi...
B) Staphylococcus epidermidis
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A patient aged 63 years, is diagnosed to have severe aplastic anemia. HLA compatible sibling is available. The best option of treatment is : A) Anti-thymocyte globulin followed by cyclosporine B) A conventional bone marrow transplantation from the HLA identical sibling C) A non-myeloablative bone marrow transplantatio...
A) Anti-thymocyte globulin followed by cyclosporine
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Cobblestone appearance is seen in A) Spring Catarrh B) Viral conjunctivitis C) Bacterial conjunctivitis D) Phlyctenular conjunctivitis
A) Spring Catarrh
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Not a molecular motor: A) Kinesin B) Dynein C) Actin D) Myosin
C) Actin
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True about anaplastic thyroid carcinoma:a) Common in elderlyb) Well encapsulatedc) Will not invade surrounding structuresd) Distant metastasis commone) Some degree of differentiation to Papillary and Follicular types seen A) acd B) bde C) ade D) ad
C) ade
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Recommended Dietary allowance in pregnancy are - A) +100-300 cal B) 35 mg Iron C) 4 mg folic acid D) 2500 mg Mg
B) 35 mg Iron
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Which of the following is not a feature of chronic tonsillitis? A) Fever B) Halitosis C) Recurrent attacks of sore throat D) Choking spells at night
A) Fever
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Which of the following muscle relaxants causes maximal pain on injection – A) Succinyl choline B) Vecuronium C) Rocuronium D) Cistracurium
C) Rocuronium
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Steroids are indicated in all of the following forms of tuberculosis except: A) Meningitis B) Pericarditis C) Ileo-caecal tuberculosis D) Adrenal involvement
C) Ileo-caecal tuberculosis
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Which of the following is false about viral thyroditis? A) Self limiting B) Painful C) Initial hypothyroid state D) Raised ESR
C) Initial hypothyroid state
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Expansible pulsating secondary metastasis is a feature of A) Basal cell carcinoma B) Renal cell carcinoma C) Osteogenic sarcoma D) Carcinoma prostate
B) Renal cell carcinoma
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Most common cause of bleeding for massive hemothorax in blunt trauma to chest is from A) Intercostal vessels B) Bronchial vessels C) Pulmonary vessels D) Internal mammary aery
A) Intercostal vessels
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The main clinical significance of sliding type hiatus hernia is: A) Propensity for GERD B) High risk of barrett's esophagus C) High chance for dieulafoy's lesion D) Dysphagia is common
A) Propensity for GERD
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The fascia of Denonvilliers - A) Membranous layer of fascia of the thigh B) Perirenal fascia C) Fascia between the rectal ampulla and the prostate and the seminal vesicles D) Posterior layer of perirenal fascia
C) Fascia between the rectal ampulla and the prostate and the seminal vesicles
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How many items are there in Mini mental state examination (MMSE)? A) 10 B) 15 C) 20 D) 30
D) 30
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Accidental from a needle stick, an unknown quantity of blood from an AIDS patient is injected into a nurse, lab reports of the patient show CD4 count 20/microL and a viral RNA load of more than 10^7copies/ml. What action should be taken regarding the treatment of the nurse A) Monitor the nurse's blood to determine whe...
D) Administer zidovudine with lamivudine for 4weeks.
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According to Lecompte (1987), the following are the recommendations for topical application of high potency fluoride products EXCEPT- A) No more than 2 g of gel per tray or approximately 40% of tray capacity should be dispensed. B) The use of a saliva ejector during the procedure is recommended. C) Following the proce...
C) Following the procedure, the patient should be instructed not to expectorate.
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Ion required for exocytosis is - A) Potassium B) Sodium C) Calcium D) Magnesium
C) Calcium
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Essential radiological feature of acute mastoiditis is: A) Temporal bone pneumatization B) Clouding of air cells of mastoid C) Rarefaction of petrous bone D) Thickening of temporal bone
B) Clouding of air cells of mastoid
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All the following are features of Wilson's disease except: A) Increased copper content in liver B) Increased ceruloplasmin C) Mental changes D) Features of chronic active hepatitis
B) Increased ceruloplasmin
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Pelvic exentration is known as ? A) Miles Operation B) Lyods operation C) Finch operation D) Brunshwings operation
D) Brunshwings operation
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Seen in a fresh dead body, which of the following features is suggestive of antemortem drowning? A) Fine leathery forth B) Thick mucoid forth C) Blood stained forth D) Any of the above
A) Fine leathery forth
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What is the latest reference to body length in ICD-10 to call it perinatal moality rate? A) 28cm B) 30cm C) 35cm D) 38cm
C) 35cm
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Palpatory thud audible slap is seen in: A) Tracheal foreign body B) Bronchial foregion body C) Laryngeal foreign body D) None
A) Tracheal foreign body
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An example for primary prevention of dental diseases is: A) Scaling & polishing and filling B) Extractions, RCT and periodontal surgeries C) Wearing gloves and sterilization of the instruments D) Replacements of Lost teeth and orthodontic treatments
C) Wearing gloves and sterilization of the instruments
Answer the following medical question with the correct option:
Pseudogestational sac is seen in A) Missed aboion B) Threatened aboion C) Inevitable aboion D) Ectopic pregnancy
D) Ectopic pregnancy
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A 50 years old patient presented to the skin OPD with erythematous scaly plaques over trunk and extremities for last l0 years. Lesions are occasionally itchy. There is history of remission and relapse with exacerbation during winters. Most likely diagnosis is? A) Lichen planus B) Psoriasis vulgaris C) Pityriasis rosea...
B) Psoriasis vulgaris
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Child with primary amenorrhoea with negative progesterone challenge test but positive combined progesterone and estrogen test. Diagnosis may be : A) Mullerian agenesis B) PCOSD C) Asherman syndrome D) Prolactinoma
D) Prolactinoma
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The average whey/casein ratio in breast milk is: A) 60:40:00 B) 80:20:00 C) 0.888888889 D) 40:60
A) 60:40:00
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All of the following agents act by intracellular receptors EXCEPT: A) Thyroid hormones B) Vitamin D C) Insulin D) Steroids
C) Insulin
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Initial amino acid in prokaryotic protein synthesis ? A) Arginine B) Methionine C) Formyl-methionine D) Alanine
C) Formyl-methionine
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"Tear drop" sign on X-ray PNS is seen in A) Blow out fracture of the floor of the orbit B) Comminuted fracture of the maxilla C) Fracture of the nasal bone D) Fracture of the mandible
A) Blow out fracture of the floor of the orbit
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Which classification is used to divide the liver into segments? A) Couinaud B) Muhe C) Starzl D) Anatomical
A) Couinaud
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In a patient with compensated liver cirrhosis presented with history of variceal bleed. The treatment of choice in this patient is - A) Propranolol B) Liver transplantation C) TIPS (Transjugular intrahepatic poal shunt) D) Endoscopic sclerotherapy
D) Endoscopic sclerotherapy
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During an emergency thoracotomy, the incision is made > 1cm lateral to the sternal margin. This will preserve which of the following structures? A) Intercostal aery B) Superficial epigastric aery C) Internal mammary aery D) Intercostal vein
C) Internal mammary aery
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Causative organism of rheumatic fever - A) Group A Streptococci B) Staphylococci C) Group B Streptococci D) Group D Streptococci
A) Group A Streptococci
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Kliiver-Bucy syndrome is associated with lesion in the following area of brain A) Amygdala B) Cerebral cortex C) Hippocampus D) Mammillary body
A) Amygdala
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Surest sign of brain stem death A) Absent Doll's eye reflex B) Fixed dilated pupil not reacting to light C) Cheyne Stokes breathing D) Decerebrate posture
B) Fixed dilated pupil not reacting to light
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Stereoanesthesia is due to lesion ofa) Nucleus Gracilisb) Nucleus cuneatusc) Cerebral cortexd) Spinothalamic tract A) abc B) bc C) acd D) bcd
A) abc
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A 70-years old male presented with asymptomatic white patch on oral cavity following application of the denture. Treatment of choice is A) Low does radiotherapy B) Biopsy of the all the tissues C) Asceaining that denture is fitted properly D) Antibiotics
C) Asceaining that denture is fitted properly
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Radiological hallmark of primary tuberculosis in childhood is- A) Ghon's focus B) Normal chest Xray C) Lymphadenopathy D) Pleural effusion
C) Lymphadenopathy
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Positive shick's test indicates that person is ? A) Immune to diptheria B) Hypersensitive to diptheria C) Susceptible to diptheria D) Carrier of diptheria
C) Susceptible to diptheria
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Dependency' ratio includes - A) Less than 15 years B) Less than85 years C) 30-50 years D) None
A) Less than 15 years
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All the following are indications for termination of pregnancy in APH patient except: A) 37 weeks B) IUD C) Transverse lie D) Continuous bleeding
C) Transverse lie
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An eight-month-old female infant presented with recurrent episodes of hypoglycemia, especially if time interval of feeding is increased. Dicarboxylic acid is present in the urine. Urine ketone bodies is negative. The child responded well to IV Glucose, less fat and more carbohydrate diet, frequent feeding. The child wa...
B) Lack of ATP to support gluconeogenesis
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Hypersensitivity vasculitis usually involve A) Aerioles B) Post capillary venules C) Capillaries D) Medium sized aeries
B) Post capillary venules
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Amino acid absorption is by: A) Facilitated transport B) Passive transport C) Active transport D) Pinocytosis
C) Active transport
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Hyponatremia in multiple myeloma is - A) TRUE B) Relative C) Absolute D) Pseudo
D) Pseudo
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Index case is the - A) First case in a community B) Case getting infection from primary case C) Case getting infection from secondary case D) First case detected by investigator
D) First case detected by investigator
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Gastrojejernostomy surgery belongs to A) Clean surgery B) Contaminated surgery C) Clean contaminated surgery D) Dirty surgery
C) Clean contaminated surgery
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Hand and foot syndrome is due to ? A) Vincristine B) Cisplatin C) 5 FU D) Azathioprine
C) 5 FU
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Gaisbock syndrome is better known as? A) Primary familial polycythemia B) High-altitude erythrocytosis C) Spurious polycythemia D) Polycythemia vera
C) Spurious polycythemia
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After an incised wound, new collagen fibrils are seen along with a thick layer of growing epithelium. The approximate age of the wound is - A) 12-24 hours B) 24-72 hours C) 4-5 days D) About 1 week
C) 4-5 days
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Thyrotoxic periodic paralysis leads to extreme muscle weakness due to? A) Hypokalemia B) Hypocalcemia C) Hypomagnesemia D) Hyponatremia
A) Hypokalemia
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vitamin involved in 1 carbon metabolism A) Folic acid B) Thiamine C) biotin D) niacin
A) Folic acid
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Cauliflower ear is - A) Keloid B) Perchondritis in Boxers C) Squamous cell carcinoma D) Anaplastic cell carcinoma
B) Perchondritis in Boxers
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Which of the following diuretics is contraindicated in the presence of cardiac failure? A) Mannitol B) Spironolactone C) Furosemide D) Hydrochlorothiazide
A) Mannitol
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Snow blindness is caused by : A) Ultravoilet rays B) Infrarads C) Microwaves D) Defect in mirror
A) Ultravoilet rays
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The most common neoplasm among HIV positive homosexual males: A) Non-Hodgkin's lymphoma B) Glomus tumor C) Kaposi's sarcoma D) None of the above
C) Kaposi's sarcoma
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Hyponatremia in multiple myeloma is A) TRUE B) Relative C) Absolute D) Pseudo
D) Pseudo
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Schiller-Duval bodies are seen in- A) Teratoma B) Seminoma C) Yolk sac tumour D) Chorio Carcinoma
C) Yolk sac tumour
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Which one of the following disorders is related to sense of unreality? A) Depersonalization disorder B) Derealization disorder C) Delusion D) Phobias
A) Depersonalization disorder
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Floaters can be seen in following except A) Vitreous haemorrhage B) Retinal detachment C) Uveitis D) Acute congestive Glaucoma
D) Acute congestive Glaucoma
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Term psychoanalysis was coined by? A) Eysenck B) Freud C) Jung D) Adler
B) Freud
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CSOM with Picket fence fever is seen in A) Meningitis B) Sigmoid Sinus Thrombosis C) Brain Abscess D) Extradural Abscess
B) Sigmoid Sinus Thrombosis
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Which dietary deficiency of a vitamin can cause Pellagra. A) Vitamin C B) Niacin C) Vitamin D D) Biotin
B) Niacin
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Good prognostic factor for schizophrenia is ? A) Blunted affect B) Early onset C) Presence of depression D) Male sex
C) Presence of depression
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All drug inhibit bacterial cell wall synthesis EXCEPT A) Spectinomycin B) Vancomycin C) Aztreonam D) Cephalexin
A) Spectinomycin
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The most common cause of death in Kaposi's Sarcoma is - A) Dissemination B) AIDS C) Massive pulmonary haemorrhage D) Diabetes mellitus
C) Massive pulmonary haemorrhage
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Longest and thinnest extrocular muscle - A) SR B) IR C) SO D) IO
C) SO
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Ribosomes has following enzymatic activity? A) Peptidyl transferase B) Peptidase C) Aminoacyl tRNA synthetase D) GTPase
A) Peptidyl transferase
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Inhibin inhibits the secretion of which hormone : A) FSH B) LH C) Estrogen D) Prolactin
A) FSH
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True regarding traumatic facial nerve palsy is all, except A) Usually occurs with transverse petrous temporal bone fracture B) Usually occurs with longitudinal petrous temporal bone fracture C) Posttraumatic facial nerve palsy may be complete at the time of presentation D) Decompression of the canal can be useful trea...
B) Usually occurs with longitudinal petrous temporal bone fracture
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Mean Hb values in two population groups are compared by A) Paired t test B) Unpaired t test C) Chi square test D) Fischer test
B) Unpaired t test
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A chest physician performs bronchoscopy in the procedure room of the out patient depament. To make the instrument safe for use in the next patient waiting outside, the most appropriate method to disinfect the endoscope is by - A) 70 % alcohol for 5 min B) 2% glutaraldehyde for 20 min C) 2% formaldehyde for 10 min D) 1...
B) 2% glutaraldehyde for 20 min
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Most important amino acid for formation Neutrophilic extracellular trap (NET) is A) Leucine B) Methionine C) Citrulline D) Valine
C) Citrulline
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All muscles of the pharynx are supplied by pharyngeal plexus, EXCEPT? A) Inferior constrictors B) Salpingopharyngeus C) Stylopharyngeus D) None of the above
C) Stylopharyngeus
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On exertion urine stream increases in - A) Prostate enlargement B) Marion's disease C) Post. urethral valves D) Urethral stricture
D) Urethral stricture
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Mauriac's syndrome is characterized by all except A) Diabetes B) Obesity C) Dwarfism D) Cardiomegaly
D) Cardiomegaly
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Which is not transmitted by arthropod - A) Rickettsia prowazekii B) Coxiella burnetii C) Rickettsia akari D) Rickettsia rickettsii
B) Coxiella burnetii
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All of the following are true about Herpes group virus except- A) Ether sensitive B) May cause malignancy C) HSV II involves below diaphragm D) Burkitt's lymphoma involves Tcells
D) Burkitt's lymphoma involves Tcells
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The diabetes control and complication trial (DCCT) provided definitive proof that reduction In chronic hyperglycemia helps to improve - A) Microvascular complications of type 1 DM B) Microvascular complications of type 1 DM C) Microvascular complications of type 2 DM D) Macro vascular complications of type 2 DM
A) Microvascular complications of type 1 DM
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. True about polio is all except: A) Sabin vaccine is attenuated, oral vaccine B) Salk is a killed formalized vaccine used C) Vaccine induced polio is usually due to Type 2 virus D) Most common type of virus in epidemics is Type 1
C) Vaccine induced polio is usually due to Type 2 virus
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Strawberry gingivitis is seen in: A) Wegener's Granulomatosis B) Scorbutic Gingivitis C) Plasma Cell Gingivitis D) Leukemic Gingivitis
A) Wegener's Granulomatosis
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Bleomycin toxicity is characterized by destruction of: A) Endothelial cells B) Type I pneumocytes C) Type II pneumocytes D) Alveolar macrophages
B) Type I pneumocytes