|
|
""" |
|
|
DocumentAnalysisAgent for Patent Wake-Up Scenario |
|
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|
|
|
Analyzes patent documents to extract key information for valorization: |
|
|
- Patent structure (title, abstract, claims, description) |
|
|
- Technical assessment (TRL, innovations, domains) |
|
|
- Commercialization potential |
|
|
""" |
|
|
|
|
|
from typing import Optional, Tuple |
|
|
import json |
|
|
import re |
|
|
from loguru import logger |
|
|
from langchain_core.prompts import ChatPromptTemplate |
|
|
from langchain_core.output_parsers import JsonOutputParser |
|
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|
|
|
from ..base_agent import BaseAgent, Task |
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|
from ...llm.langchain_ollama_client import LangChainOllamaClient |
|
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from ...workflow.langgraph_state import PatentAnalysis, Claim |
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|
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class DocumentAnalysisAgent(BaseAgent): |
|
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""" |
|
|
Specialized agent for patent document analysis. |
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|
Extracts and analyzes patent content for commercialization assessment. |
|
|
""" |
|
|
|
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|
def __init__(self, llm_client: LangChainOllamaClient, memory_agent=None, vision_ocr_agent=None): |
|
|
""" |
|
|
Initialize DocumentAnalysisAgent. |
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|
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|
Args: |
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|
llm_client: LangChain Ollama client |
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|
memory_agent: Optional memory agent for context retrieval |
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|
vision_ocr_agent: Optional VisionOCRAgent for enhanced text extraction |
|
|
""" |
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self.name = "DocumentAnalysisAgent" |
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self.description = "Patent document analysis and assessment" |
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self.llm_client = llm_client |
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self.memory_agent = memory_agent |
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self.vision_ocr_agent = vision_ocr_agent |
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self.llm = llm_client.get_llm('standard') |
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self.structure_chain = self._create_structure_chain() |
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self.assessment_chain = self._create_assessment_chain() |
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if vision_ocr_agent: |
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logger.info("Initialized DocumentAnalysisAgent with VisionOCR support") |
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else: |
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logger.info("Initialized DocumentAnalysisAgent") |
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|
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def _create_structure_chain(self): |
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|
"""Create chain for extracting patent structure""" |
|
|
parser = JsonOutputParser() |
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|
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|
prompt = ChatPromptTemplate.from_messages([ |
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|
("system", """You are an expert patent analyst. Extract structured information from patent text. |
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|
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|
CRITICAL: You MUST respond with ONLY valid JSON. Do NOT include any explanatory text, notes, or comments. |
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|
Do NOT say "Based on the provided text..." or "Note that..." or any other prose. |
|
|
Your response must start with {{ and end with }}. |
|
|
If information is missing, use null or empty arrays []."""), |
|
|
("human", """ |
|
|
Analyze this patent text and extract the following information: |
|
|
|
|
|
1. Patent ID/Number (if mentioned) |
|
|
2. Title |
|
|
3. Abstract |
|
|
4. All independent claims (claims that don't depend on other claims) |
|
|
5. All dependent claims (claims that reference other claims) |
|
|
6. Inventors |
|
|
7. Assignees |
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|
8. Filing and publication dates (if mentioned) |
|
|
9. IPC classification codes (if mentioned) |
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Patent Text: |
|
|
{patent_text} |
|
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|
|
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{format_instructions} |
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|
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|
IMPORTANT: Respond with ONLY the JSON object. No additional text before or after the JSON. |
|
|
""") |
|
|
]) |
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return prompt | self.llm | parser |
|
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def _create_assessment_chain(self): |
|
|
"""Create chain for technology and commercialization assessment""" |
|
|
parser = JsonOutputParser() |
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|
|
|
prompt = ChatPromptTemplate.from_messages([ |
|
|
("system", """You are an expert in technology commercialization and TRL assessment. |
|
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|
|
|
CRITICAL: You MUST respond with ONLY valid JSON. Do NOT include any explanatory text, notes, or comments. |
|
|
Do NOT say "I'll provide an assessment..." or "Please note that..." or any other prose. |
|
|
Your response must start with {{ and end with }}. |
|
|
If information is missing, provide reasonable estimates based on available data."""), |
|
|
("human", """ |
|
|
Assess this patent for commercialization potential: |
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|
|
Title: {title} |
|
|
Abstract: {abstract} |
|
|
Key Claims: {key_claims} |
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|
|
{format_instructions} |
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|
|
|
TRL Guidelines: |
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|
- TRL 1-3: Basic research, proof of concept |
|
|
- TRL 4-6: Technology development, prototype testing |
|
|
- TRL 7-9: System demonstration, operational |
|
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|
|
|
Provide assessment as JSON with: |
|
|
1. technical_domains: 3-5 technical domains (array of strings) |
|
|
2. key_innovations: 3-5 key innovations (array of strings) |
|
|
3. novelty_assessment: Brief assessment of what makes this novel (string) |
|
|
4. trl_level: Technology readiness level 1-9 (integer) |
|
|
5. trl_justification: Reasoning for TRL level (string) |
|
|
6. commercialization_potential: High/Medium/Low (string) |
|
|
7. potential_applications: 3-5 potential applications (array of strings) |
|
|
8. confidence_score: 0.0-1.0 (float) |
|
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|
|
|
IMPORTANT: Respond with ONLY the JSON object. No additional text before or after the JSON. |
|
|
""") |
|
|
]) |
|
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|
|
|
return prompt | self.llm | parser |
|
|
|
|
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async def analyze_patent(self, patent_path: str, fast_mode: bool = True) -> PatentAnalysis: |
|
|
""" |
|
|
Analyze a patent document and return structured analysis. |
|
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|
|
|
Args: |
|
|
patent_path: Path to patent PDF or text file |
|
|
fast_mode: Use fast heuristic extraction (default True for speed) |
|
|
|
|
|
Returns: |
|
|
PatentAnalysis object with all extracted information |
|
|
""" |
|
|
logger.info(f"📄 Analyzing patent: {patent_path}") |
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|
|
patent_text = await self._extract_patent_text(patent_path) |
|
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|
|
if fast_mode: |
|
|
logger.info("Using fast heuristic extraction mode") |
|
|
title, abstract = self._extract_fallback_title_abstract(patent_text) |
|
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|
|
structure = { |
|
|
'title': title, |
|
|
'abstract': abstract, |
|
|
'independent_claims': [], |
|
|
'dependent_claims': [], |
|
|
'inventors': [], |
|
|
'assignees': [], |
|
|
'patent_id': None, |
|
|
'ipc_classification': [] |
|
|
} |
|
|
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|
|
assessment = { |
|
|
'technical_domains': ['Technology Transfer', 'Innovation'], |
|
|
'key_innovations': ['Patent document analysis'], |
|
|
'novelty_assessment': 'Preliminary assessment based on document content', |
|
|
'trl_level': 6, |
|
|
'trl_justification': 'Estimated based on document type', |
|
|
'commercialization_potential': 'Medium', |
|
|
'potential_applications': ['Technology licensing', 'Research collaboration'], |
|
|
'confidence_score': 0.7 |
|
|
} |
|
|
|
|
|
else: |
|
|
|
|
|
logger.info("Using LLM-based extraction (slower but more accurate)") |
|
|
|
|
|
|
|
|
context = None |
|
|
if self.memory_agent: |
|
|
try: |
|
|
context = await self.memory_agent.retrieve_relevant_context( |
|
|
query=f"patent analysis {patent_path}", |
|
|
context_type="semantic", |
|
|
top_k=2 |
|
|
) |
|
|
if context: |
|
|
logger.debug(f"Retrieved {len(context)} context documents from memory") |
|
|
except Exception as e: |
|
|
logger.warning(f"Memory retrieval failed: {e}") |
|
|
|
|
|
|
|
|
logger.info("Extracting patent structure...") |
|
|
parser = JsonOutputParser() |
|
|
|
|
|
structure = await self.structure_chain.ainvoke({ |
|
|
"patent_text": patent_text[:8000], |
|
|
"format_instructions": parser.get_format_instructions() |
|
|
}) |
|
|
|
|
|
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|
|
logger.info("Assessing technology and commercialization potential...") |
|
|
|
|
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|
|
|
independent_claims = structure.get('independent_claims') or [] |
|
|
|
|
|
valid_claims = [c for c in independent_claims if c is not None and isinstance(c, dict)] |
|
|
key_claims = "\n".join([ |
|
|
f"Claim {c.get('claim_number', 'N/A')}: {c.get('claim_text', '')[:200]}..." |
|
|
for c in valid_claims[:3] |
|
|
]) if valid_claims else "No claims available" |
|
|
|
|
|
parser = JsonOutputParser() |
|
|
assessment = await self.assessment_chain.ainvoke({ |
|
|
"title": structure.get('title', 'Unknown'), |
|
|
"abstract": structure.get('abstract', '')[:1000], |
|
|
"key_claims": key_claims, |
|
|
"format_instructions": parser.get_format_instructions() |
|
|
}) |
|
|
|
|
|
|
|
|
analysis = self._build_patent_analysis(structure, assessment, patent_text) |
|
|
|
|
|
logger.success(f"✅ Patent analysis complete: TRL {analysis.trl_level}, " |
|
|
f"{len(analysis.key_innovations)} innovations identified") |
|
|
|
|
|
return analysis |
|
|
|
|
|
async def _extract_patent_text(self, patent_path: str) -> str: |
|
|
""" |
|
|
Extract text from patent PDF or text file. |
|
|
|
|
|
Args: |
|
|
patent_path: Path to patent file |
|
|
|
|
|
Returns: |
|
|
Extracted text content (clean, without metadata headers) |
|
|
""" |
|
|
try: |
|
|
if patent_path.endswith('.pdf'): |
|
|
|
|
|
import fitz |
|
|
|
|
|
doc = fitz.open(patent_path) |
|
|
text_parts = [] |
|
|
num_pages = len(doc) |
|
|
|
|
|
|
|
|
for page_num in range(num_pages): |
|
|
page = doc[page_num] |
|
|
text_parts.append(page.get_text()) |
|
|
|
|
|
doc.close() |
|
|
result = "\n\n".join(text_parts) |
|
|
|
|
|
logger.info(f"Extracted {num_pages} pages from PDF") |
|
|
|
|
|
else: |
|
|
|
|
|
with open(patent_path, 'r', encoding='utf-8') as f: |
|
|
result = f.read() |
|
|
|
|
|
|
|
|
if len(result) < 100: |
|
|
logger.warning(f"Document very short ({len(result)} chars)") |
|
|
|
|
|
return result |
|
|
|
|
|
except Exception as e: |
|
|
logger.error(f"Failed to extract text from {patent_path}: {e}") |
|
|
|
|
|
return self._get_mock_patent_text() |
|
|
|
|
|
async def _extract_with_ocr(self, patent_path: str) -> Optional[str]: |
|
|
""" |
|
|
Extract text using VisionOCRAgent (for image-based PDFs or enhanced extraction). |
|
|
|
|
|
Note: This requires converting PDF pages to images first. |
|
|
For the demo, this is a foundation for future enhancement. |
|
|
|
|
|
Args: |
|
|
patent_path: Path to patent PDF |
|
|
|
|
|
Returns: |
|
|
OCR-extracted text or None if OCR not available |
|
|
""" |
|
|
if not self.vision_ocr_agent or not self.vision_ocr_agent.is_available(): |
|
|
return None |
|
|
|
|
|
try: |
|
|
logger.info("Enhanced OCR extraction available (foundation for future use)") |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
return None |
|
|
|
|
|
except Exception as e: |
|
|
logger.warning(f"OCR extraction failed: {e}") |
|
|
return None |
|
|
|
|
|
def _get_mock_patent_text(self) -> str: |
|
|
"""Get mock patent text for demonstration purposes""" |
|
|
return """ |
|
|
PATENT NUMBER: US20210123456 |
|
|
|
|
|
TITLE: AI-Powered Drug Discovery Platform Using Machine Learning |
|
|
|
|
|
ABSTRACT: |
|
|
A novel method and system for accelerating drug discovery using artificial intelligence |
|
|
and machine learning techniques. The invention provides automated analysis of molecular |
|
|
structures, prediction of drug-target interactions, and optimization of lead compounds. |
|
|
The system employs deep learning models trained on large-scale pharmaceutical databases |
|
|
to identify promising drug candidates with improved efficacy and reduced development time. |
|
|
|
|
|
CLAIMS: |
|
|
|
|
|
1. A computer-implemented method for drug discovery comprising: |
|
|
(a) receiving molecular structure data for a plurality of compounds; |
|
|
(b) processing said molecular data using a trained neural network model; |
|
|
(c) predicting binding affinity scores for each compound; |
|
|
(d) identifying top candidates based on predicted scores and safety profiles. |
|
|
|
|
|
2. The method of claim 1, wherein the neural network is a convolutional neural network |
|
|
trained on over 1 million known drug-target interactions. |
|
|
|
|
|
3. The method of claim 1, further comprising optimizing lead compounds using generative |
|
|
adversarial networks to improve pharmacokinetic properties. |
|
|
|
|
|
4. A system for automated drug discovery comprising: |
|
|
(a) a database of molecular structures and pharmaceutical data; |
|
|
(b) a machine learning module configured to predict drug efficacy; |
|
|
(c) an optimization module for refining lead compounds; |
|
|
(d) a user interface for visualizing results and candidate rankings. |
|
|
|
|
|
5. The system of claim 4, wherein the machine learning module employs ensemble methods |
|
|
combining multiple predictive models for improved accuracy. |
|
|
|
|
|
DETAILED DESCRIPTION: |
|
|
The present invention relates to pharmaceutical research and drug discovery, specifically |
|
|
to methods and systems for using artificial intelligence to accelerate the identification |
|
|
and optimization of drug candidates. Traditional drug discovery is time-consuming and |
|
|
expensive, often taking 10-15 years and costing billions of dollars. This invention |
|
|
addresses these challenges by automating key steps in the drug discovery pipeline. |
|
|
|
|
|
The system comprises a comprehensive database of molecular structures, known drug-target |
|
|
interactions, and clinical trial data. Machine learning models, including deep neural |
|
|
networks and ensemble methods, are trained on this data to learn patterns associated |
|
|
with successful drugs. The trained models can then predict the efficacy and safety of |
|
|
new compounds, dramatically reducing the time and cost of initial screening. |
|
|
|
|
|
Key innovations include: |
|
|
1. Novel neural network architecture optimized for molecular structure analysis |
|
|
2. Automated lead optimization using generative AI |
|
|
3. Integration of multi-omic data for comprehensive drug profiling |
|
|
4. Real-time candidate ranking and visualization tools |
|
|
|
|
|
The technology has been validated through retrospective analysis of FDA-approved drugs |
|
|
and prospective testing on novel compounds. Results demonstrate 70% reduction in screening |
|
|
time and identification of candidates with 40% higher predicted efficacy than traditional methods. |
|
|
|
|
|
INVENTORS: Dr. Sarah Chen, Dr. Michael Rodriguez, Dr. Yuki Tanaka |
|
|
ASSIGNEE: BioAI Pharmaceuticals Inc. |
|
|
FILING DATE: January 15, 2021 |
|
|
PUBLICATION DATE: June 24, 2021 |
|
|
IPC: G16C 20/30, G16H 20/10, G06N 3/08 |
|
|
""" |
|
|
|
|
|
def _extract_fallback_title_abstract(self, patent_text: str) -> Tuple[str, str]: |
|
|
""" |
|
|
Extract title and abstract using simple heuristics when LLM extraction fails. |
|
|
Useful for non-standard patent formats or press releases. |
|
|
|
|
|
Args: |
|
|
patent_text: Raw text from PDF |
|
|
|
|
|
Returns: |
|
|
Tuple of (title, abstract) |
|
|
""" |
|
|
lines = [line.strip() for line in patent_text.split('\n') if line.strip()] |
|
|
|
|
|
|
|
|
title = "Document Analysis" |
|
|
for line in lines[:15]: |
|
|
|
|
|
if (len(line) > 15 and len(line) < 150 and |
|
|
not line.startswith('-') and |
|
|
not line.startswith('=') and |
|
|
not all(c in '=-_*' for c in line)): |
|
|
title = line |
|
|
break |
|
|
|
|
|
|
|
|
abstract_parts = [] |
|
|
found_title = False |
|
|
skip_count = 0 |
|
|
|
|
|
for line in lines: |
|
|
|
|
|
if not found_title: |
|
|
if line == title: |
|
|
found_title = True |
|
|
skip_count = 0 |
|
|
continue |
|
|
|
|
|
|
|
|
if skip_count < 2: |
|
|
skip_count += 1 |
|
|
if len(line) < 50: |
|
|
continue |
|
|
|
|
|
|
|
|
if len(line) > 50: |
|
|
abstract_parts.append(line) |
|
|
|
|
|
|
|
|
joined = ' '.join(abstract_parts) |
|
|
if len(joined) > 400: |
|
|
abstract = joined[:497] + "..." |
|
|
break |
|
|
else: |
|
|
|
|
|
if len(abstract_parts) == 0: |
|
|
for line in lines[:30]: |
|
|
if len(line) > 50: |
|
|
abstract_parts.append(line) |
|
|
if len(' '.join(abstract_parts)) > 300: |
|
|
break |
|
|
|
|
|
abstract = ' '.join(abstract_parts) if abstract_parts else "No summary available" |
|
|
|
|
|
|
|
|
if len(abstract) > 500 and not abstract.endswith("..."): |
|
|
abstract = abstract[:497] + "..." |
|
|
|
|
|
logger.info(f"Fallback extraction: title='{title[:60]}', abstract={len(abstract)} chars") |
|
|
return title, abstract |
|
|
|
|
|
def _build_patent_analysis(self, structure: dict, assessment: dict, patent_text: str = "") -> PatentAnalysis: |
|
|
""" |
|
|
Build PatentAnalysis object from structure and assessment data. |
|
|
|
|
|
Args: |
|
|
structure: Extracted patent structure |
|
|
assessment: Technology assessment |
|
|
patent_text: Original patent text (for fallback extraction) |
|
|
|
|
|
Returns: |
|
|
Complete PatentAnalysis object |
|
|
""" |
|
|
|
|
|
|
|
|
ind_claims_raw = structure.get('independent_claims') or [] |
|
|
dep_claims_raw = structure.get('dependent_claims') or [] |
|
|
|
|
|
independent_claims = [ |
|
|
Claim(**claim) for claim in ind_claims_raw |
|
|
if claim is not None and isinstance(claim, dict) |
|
|
] |
|
|
dependent_claims = [ |
|
|
Claim(**claim) for claim in dep_claims_raw |
|
|
if claim is not None and isinstance(claim, dict) |
|
|
] |
|
|
|
|
|
|
|
|
title = structure.get('title') |
|
|
abstract = structure.get('abstract') |
|
|
|
|
|
|
|
|
if (not title or title == 'Patent Analysis' or |
|
|
not abstract or abstract == 'Abstract not available'): |
|
|
logger.info("Using fallback title/abstract extraction") |
|
|
fallback_title, fallback_abstract = self._extract_fallback_title_abstract(patent_text) |
|
|
|
|
|
if not title or title == 'Patent Analysis': |
|
|
title = fallback_title |
|
|
if not abstract or abstract == 'Abstract not available': |
|
|
abstract = fallback_abstract |
|
|
|
|
|
|
|
|
if not title: |
|
|
title = 'Document Analysis' |
|
|
if not abstract: |
|
|
abstract = 'No description available' |
|
|
|
|
|
return PatentAnalysis( |
|
|
patent_id=structure.get('patent_id') or 'UNKNOWN', |
|
|
title=title, |
|
|
abstract=abstract, |
|
|
|
|
|
|
|
|
independent_claims=independent_claims, |
|
|
dependent_claims=dependent_claims, |
|
|
total_claims=len(independent_claims) + len(dependent_claims), |
|
|
|
|
|
|
|
|
ipc_classification=structure.get('ipc_classification') or [], |
|
|
technical_domains=assessment.get('technical_domains') or ['Technology'], |
|
|
key_innovations=assessment.get('key_innovations') or [], |
|
|
novelty_assessment=assessment.get('novelty_assessment') or 'Novel approach', |
|
|
|
|
|
|
|
|
trl_level=assessment.get('trl_level') or 5, |
|
|
trl_justification=assessment.get('trl_justification') or 'Technology development stage', |
|
|
commercialization_potential=assessment.get('commercialization_potential') or 'Medium', |
|
|
potential_applications=assessment.get('potential_applications') or [], |
|
|
|
|
|
|
|
|
inventors=structure.get('inventors') or [], |
|
|
assignees=structure.get('assignees') or [], |
|
|
filing_date=structure.get('filing_date'), |
|
|
publication_date=structure.get('publication_date'), |
|
|
|
|
|
|
|
|
confidence_score=assessment.get('confidence_score') or 0.8, |
|
|
extraction_completeness=0.9 if independent_claims else 0.6 |
|
|
) |
|
|
|
|
|
async def process_task(self, task: Task) -> Task: |
|
|
""" |
|
|
Process task using agent interface. |
|
|
|
|
|
Args: |
|
|
task: Task with patent_path in metadata |
|
|
|
|
|
Returns: |
|
|
Task with PatentAnalysis result |
|
|
""" |
|
|
task.status = "in_progress" |
|
|
|
|
|
try: |
|
|
patent_path = task.metadata.get('patent_path') |
|
|
if not patent_path: |
|
|
raise ValueError("patent_path required in task metadata") |
|
|
|
|
|
analysis = await self.analyze_patent(patent_path) |
|
|
|
|
|
task.result = analysis.model_dump() |
|
|
task.status = "completed" |
|
|
|
|
|
except Exception as e: |
|
|
logger.error(f"Document analysis failed: {e}") |
|
|
task.status = "failed" |
|
|
task.error = str(e) |
|
|
|
|
|
return task |
|
|
|