leadboard / data /brd4_card.json
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boards: add proteases, nuclear receptors, epigenetics (8 boards)
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{
"board": "BRD4",
"target": "CHEMBL1163125",
"type": "IC50",
"cut": 2022,
"threshold": 6.5,
"n_train": 5595,
"n_test": 2402,
"positive_rate": 0.3859283930058285,
"noise_floor": {
"pairs": 8948,
"compounds": 627,
"median": 0.2814396191743418,
"mean": 0.44751677771143744,
"p75": 0.615224460689137,
"p90": 1.0280217133101441,
"sd_single": 0.3967347320136857
},
"baselines": {
"์ƒ์ˆ˜ ์˜ˆ์ธก": {
"auroc": 0.5,
"prauc": 0.3859283930058285,
"mae": 1.0784183108137753
},
"์ตœ๊ทผ์ ‘ ์ด์›ƒ": {
"auroc": 0.6795341268535279,
"prauc": 0.5062603292552335,
"mae": 1.0292439819281891
},
"Morgan+LightGBM": {
"auroc": 0.8614308960927359,
"prauc": 0.7769106527745347,
"mae": 0.8549645558861177
}
},
"near_threshold": 694,
"split_grade": "T",
"split_grade_note": "์ตœ์ดˆ ๋ณด๊ณ  ์—ฐ๋„ ๊ธฐ์ค€ ์‹œ๊ฐ„ ๋ถ„ํ• ",
"answer_grade": "P1",
"answer_grade_note": "์ •๋‹ต์ด ChEMBL ์— ๊ณต๊ฐœ๋˜์–ด ์žˆ๋‹ค. ์กฐํšŒ ๋ฐฉ์–ด๋Š” 8์กฐ๊ฐ€ ๋งก๋Š”๋‹ค",
"source": "ChEMBL_37",
"built": "2026-08-23"
}