---
license: mit
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# grimage

Age-calibrated mortality-risk estimator built in two stages from DNAm surrogates for plasma proteins and smoking pack-years, chronological age, and sex.

| | |
|---|---|
| **Predicts** | mortality risk |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | two-stage elastic net + Cox regression |
| **Year** | 2019 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["grimage"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Lu, Ake T., et al. "DNA methylation GrimAge strongly predicts lifespan and healthspan." Aging (Albany NY) 11 (2019): 303–327.

https://doi.org/10.18632/aging.101684