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| | 2-LTR circle formation REACT:R-HSA-164843 |
| | 2-Oxocarboxylic acid metabolism KEGG:hsa01210 |
| | 5-Phosphoribose 1-diphosphate biosynthesis REACT:R-HSA-73843 |
| | Abacavir metabolism REACT:R-HSA-2161541 |
| | Abacavir transmembrane transport REACT:R-HSA-2161517 |
| | Abacavir transport and metabolism REACT:R-HSA-2161522 |
| | Abasic sugar-phosphate removal via the single-nucleotide replacement pathway REACT:R-HSA-73930 |
| | ABC-family proteins mediated transport REACT:R-HSA-382556 |
| | ABC transporter disorders REACT:R-HSA-5619084 |
| | ABC transporters KEGG:hsa02010 |
| | ABC transporters in lipid homeostasis REACT:R-HSA-1369062 |
| | Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate REACT:R-HSA-2978092 |
| | Abortive elongation of HIV-1 transcript in the absence of Tat REACT:R-HSA-167242 |
| | Acetylation REACT:R-HSA-156582 |
| | Acetylcholine Binding And Downstream Events REACT:R-HSA-181431 |
| | Acetylcholine Neurotransmitter Release Cycle REACT:R-HSA-264642 |
| | Acetylcholine regulates insulin secretion REACT:R-HSA-399997 |
| | Acrosome Reaction REACT:R-HSA-1300645 |
| | Activated NOTCH1 Transmits Signal to the Nucleus REACT:R-HSA-2122948 |
| | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 REACT:R-HSA-5625886 |
| | Activated point mutants of FGFR2 REACT:R-HSA-2033519 |
| | activated TAK1 mediates p38 MAPK activation REACT:R-HSA-450302 |
| | Activated TLR4 signalling REACT:R-HSA-166054 |
| | Activation and oligomerization of BAK protein REACT:R-HSA-111452 |
| | Activation, myristolyation of BID and translocation to mitochondria REACT:R-HSA-75108 |
| | Activation of AKT2 REACT:R-HSA-165158 |
| | Activation of AMPA receptors REACT:R-HSA-399710 |
| | Activation of anterior HOX genes in hindbrain development during early embryogenesis REACT:R-HSA-5617472 |
| | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins REACT:R-HSA-176814 |
| | Activation of ATR in response to replication stress REACT:R-HSA-176187 |
| | Activation of BAD and translocation to mitochondria REACT:R-HSA-111447 |
| | Activation of BH3-only proteins REACT:R-HSA-114452 |
| | Activation of BIM and translocation to mitochondria REACT:R-HSA-111446 |
| | Activation of BMF and translocation to mitochondria REACT:R-HSA-139910 |
| | Activation of C3 and C5 REACT:R-HSA-174577 |
| | Activation of CaMK IV REACT:R-HSA-442745 |
| | Activation of Ca-permeable Kainate Receptor REACT:R-HSA-451308 |
| | Activation of caspases through apoptosome-mediated cleavage REACT:R-HSA-111459 |
| | Activation of DNA fragmentation factor REACT:R-HSA-211227 |
| | Activation of GABAB receptors REACT:R-HSA-991365 |
| | Activation of gene expression by SREBF (SREBP) REACT:R-HSA-2426168 |
| | Activation of G protein gated Potassium channels REACT:R-HSA-1296041 |
| | Activation of HOX genes during differentiation REACT:R-HSA-5619507 |
| | Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon REACT:R-HSA-936964 |
| | Activation of Kainate Receptors upon glutamate binding REACT:R-HSA-451326 |
| | Activation of Matrix Metalloproteinases REACT:R-HSA-1592389 |
| | Activation of Na-permeable Kainate Receptors REACT:R-HSA-451307 |
| | Activation of NF-kappaB in B cells REACT:R-HSA-1169091 |
| | Activation of Nicotinic Acetylcholine Receptors REACT:R-HSA-629602 |
| | Activation of NIMA Kinases NEK9, NEK6, NEK7 REACT:R-HSA-2980767 |
| | Activation of NMDA receptor upon glutamate binding and postsynaptic events REACT:R-HSA-442755 |
| | Activation of NOXA and translocation to mitochondria REACT:R-HSA-111448 |
| | Activation of PPARGC1A (PGC-1alpha) by phosphorylation REACT:R-HSA-2151209 |
| | Activation of PUMA and translocation to mitochondria REACT:R-HSA-139915 |
| | Activation of Rac REACT:R-HSA-428540 |
| | Activation of RAS in B cells REACT:R-HSA-1169092 |
| | Activation of SMO REACT:R-HSA-5635838 |
| | Activation of the AP-1 family of transcription factors REACT:R-HSA-450341 |
| | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S REACT:R-HSA-72662 |
| | Activation of the phototransduction cascade REACT:R-HSA-2485179 |
| | Activation of the pre-replicative complex REACT:R-HSA-68962 |
| | Activation of the TFAP2 (AP-2) family of transcription factors REACT:R-HSA-8866907 |
| | Activation of TRKA receptors REACT:R-HSA-187015 |
| | Activation, translocation and oligomerization of BAX REACT:R-HSA-114294 |
| | Activin signaling KEGG:hsa_M00681 |
| | Acute myeloid leukemia KEGG:hsa05221 |
| | Acyl chain remodeling of CL REACT:R-HSA-1482798 |
| | Acyl chain remodeling of DAG and TAG REACT:R-HSA-1482883 |
| | Acyl chain remodelling of PC REACT:R-HSA-1482788 |
| | Acyl chain remodelling of PE REACT:R-HSA-1482839 |
| | Acyl chain remodelling of PG REACT:R-HSA-1482925 |
| | Acyl chain remodelling of PI REACT:R-HSA-1482922 |
| | Acyl chain remodelling of PS REACT:R-HSA-1482801 |
| | Acylglycerol degradation KEGG:hsa_M00098 |
| | Adaptive Immune System REACT:R-HSA-1280218 |
| | Adenine ribonucleotide biosynthesis, IMP => ADP,ATP KEGG:hsa_M00049 |
| | Adenosine P1 receptors REACT:R-HSA-417973 |
| | Adenylate cyclase activating pathway REACT:R-HSA-170660 |
| | Adenylate cyclase inhibitory pathway REACT:R-HSA-170670 |
| | Adherens junction KEGG:hsa04520 |
| | Adherens junctions interactions REACT:R-HSA-418990 |
| | Adipocytokine signaling pathway KEGG:hsa04920 |
| | ADP signalling through P2Y purinoceptor 1 REACT:R-HSA-418592 |
| | ADP signalling through P2Y purinoceptor 12 REACT:R-HSA-392170 |
| | Adrenaline,noradrenaline inhibits insulin secretion REACT:R-HSA-400042 |
| | Adrenaline signalling through Alpha-2 adrenergic receptor REACT:R-HSA-392023 |
| | Adrenergic signaling in cardiomyocytes KEGG:hsa04261 |
| | Adrenoceptors REACT:R-HSA-390696 |
| | Advanced glycosylation endproduct receptor signaling REACT:R-HSA-879415 |
| | Aflatoxin activation and detoxification REACT:R-HSA-5423646 |
| | African trypanosomiasis KEGG:hsa05143 |
| | AGE-RAGE signaling pathway in diabetic complications KEGG:hsa04933 |
| | Agmatine biosynthesis REACT:R-HSA-351143 |
| | AKT-mediated inactivation of FOXO1A REACT:R-HSA-211163 |
| | AKT phosphorylates targets in the cytosol REACT:R-HSA-198323 |
| | AKT phosphorylates targets in the nucleus REACT:R-HSA-198693 |
| | Alanine, aspartate and glutamate metabolism KEGG:hsa00250 |
| | Alcoholism KEGG:hsa05034 |
| | Aldosterone-regulated sodium reabsorption KEGG:hsa04960 |
| | Aldosterone synthesis and secretion KEGG:hsa04925 |
| | ALKBH2 mediated reversal of alkylation damage REACT:R-HSA-112122 |
| | ALKBH3 mediated reversal of alkylation damage REACT:R-HSA-112126 |
| | Allograft rejection KEGG:hsa05330 |
| | Alpha-defensins REACT:R-HSA-1462054 |
| | alpha-linolenic acid (ALA) metabolism REACT:R-HSA-2046106 |
| | alpha-Linolenic acid metabolism KEGG:hsa00592 |
| | alpha-linolenic (omega3) and linoleic (omega6) acid metabolism REACT:R-HSA-2046104 |
| | Alpha-oxidation of phytanate REACT:R-HSA-389599 |
| | Alternative complement activation REACT:R-HSA-173736 |
| | Alzheimer's disease KEGG:hsa05010 |
| | AMER1 mutants destabilize the destruction complex REACT:R-HSA-4839748 |
| | Amine-derived hormones REACT:R-HSA-209776 |
| | Amine ligand-binding receptors REACT:R-HSA-375280 |
| | Amine Oxidase reactions REACT:R-HSA-140179 |
| | Amino Acid conjugation REACT:R-HSA-156587 |
| | Amino acid synthesis and interconversion (transamination) REACT:R-HSA-70614 |
| | Amino acid transport across the plasma membrane REACT:R-HSA-352230 |
| | Aminoacyl-tRNA biosynthesis KEGG:hsa00970 |
| | Aminoacyl-tRNA biosynthesis, eukaryotes KEGG:hsa_M00359 |
| | Amino sugar and nucleotide sugar metabolism KEGG:hsa00520 |
| | Amoebiasis KEGG:hsa05146 |
| | Amphetamine addiction KEGG:hsa05031 |
| | AMPK inhibits chREBP transcriptional activation activity REACT:R-HSA-163680 |
| | AMPK signaling pathway KEGG:hsa04152 |
| | Amplification of signal from the kinetochores REACT:R-HSA-141424 |
| | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal REACT:R-HSA-141444 |
| | Amyloid fiber formation REACT:R-HSA-977225 |
| | Amyotrophic lateral sclerosis (ALS) KEGG:hsa05014 |
| | Anchoring fibril formation REACT:R-HSA-2214320 |
| | Anchoring of the basal body to the plasma membrane REACT:R-HSA-5620912 |
| | Androgen biosynthesis REACT:R-HSA-193048 |
| | Antagonism of Activin by Follistatin REACT:R-HSA-2473224 |
| | Antifolate resistance KEGG:hsa01523 |
| | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers REACT:R-HSA-983695 |
| | Antigen Presentation: Folding, assembly and peptide loading of class I MHC REACT:R-HSA-983170 |
| | Antigen processing and presentation KEGG:hsa04612 |
| | Antigen processing-Cross presentation REACT:R-HSA-1236975 |
| | Antigen processing: Ubiquitination & Proteasome degradation REACT:R-HSA-983168 |
| | Antimicrobial peptides REACT:R-HSA-6803157 |
| | Antiviral mechanism by IFN-stimulated genes REACT:R-HSA-1169410 |
| | APC/C:Cdc20 mediated degradation of Cyclin B REACT:R-HSA-174048 |
| | APC/C:Cdc20 mediated degradation of mitotic proteins REACT:R-HSA-176409 |
| | APC/C:Cdc20 mediated degradation of Securin REACT:R-HSA-174154 |
| | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 REACT:R-HSA-174178 |
| | APC/C complex KEGG:hsa_M00389 |
| | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint REACT:R-HSA-179419 |
| | APC-Cdc20 mediated degradation of Nek2A REACT:R-HSA-179409 |
| | APC/C-mediated degradation of cell cycle proteins REACT:R-HSA-174143 |
| | APC truncation mutants are not K63 polyubiquitinated REACT:R-HSA-5467333 |
| | APC truncation mutants have impaired AXIN binding REACT:R-HSA-5467337 |
| | Apelin signaling pathway KEGG:hsa04371 |
| | APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway REACT:R-HSA-5649702 |
| | APOBEC3G mediated resistance to HIV-1 infection REACT:R-HSA-180689 |
| | Apoptosis KEGG:hsa04210 |
| | Apoptosis REACT:R-HSA-109581 |
| | Apoptosis induced DNA fragmentation REACT:R-HSA-140342 |
| | Apoptosis - multiple species KEGG:hsa04215 |
| | Apoptotic cleavage of cell adhesion proteins REACT:R-HSA-351906 |
| | Apoptotic cleavage of cellular proteins REACT:R-HSA-111465 |
| | Apoptotic execution phase REACT:R-HSA-75153 |
| | Apoptotic factor-mediated response REACT:R-HSA-111471 |
| | Apoptotic machinery KEGG:hsa_M00685 |
| | Aquaporin-mediated transport REACT:R-HSA-445717 |
| | Arachidonate production from DAG REACT:R-HSA-426048 |
| | Arachidonic acid metabolism KEGG:hsa00590 |
| | Arachidonic acid metabolism REACT:R-HSA-2142753 |
| | Arginine and proline metabolism KEGG:hsa00330 |
| | Arginine biosynthesis KEGG:hsa00220 |
| | ARL13B-mediated ciliary trafficking of INPP5E REACT:R-HSA-5624958 |
| | ARMS-mediated activation REACT:R-HSA-170984 |
| | Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 REACT:R-HSA-211957 |
| | Arrhythmogenic right ventricular cardiomyopathy (ARVC) KEGG:hsa05412 |
| | Aryl hydrocarbon receptor signalling REACT:R-HSA-8937144 |
| | Ascorbate and aldarate metabolism KEGG:hsa00053 |
| | Asparagine N-linked glycosylation REACT:R-HSA-446203 |
| | Assembly of collagen fibrils and other multimeric structures REACT:R-HSA-2022090 |
| | Assembly Of The HIV Virion REACT:R-HSA-175474 |
| | Assembly of the ORC complex at the origin of replication REACT:R-HSA-68616 |
| | Assembly of the pre-replicative complex REACT:R-HSA-68867 |
| | Assembly of Viral Components at the Budding Site REACT:R-HSA-168316 |
| | Association of licensing factors with the pre-replicative complex REACT:R-HSA-69298 |
| | Association of TriC/CCT with target proteins during biosynthesis REACT:R-HSA-390471 |
| | Asthma KEGG:hsa05310 |
| | Astrocytic Glutamate-Glutamine Uptake And Metabolism REACT:R-HSA-210455 |
| | Asymmetric localization of PCP proteins REACT:R-HSA-4608870 |
| | A tetrasaccharide linker sequence is required for GAG synthesis REACT:R-HSA-1971475 |
| | ATF4 activates genes REACT:R-HSA-380994 |
| | ATF6 (ATF6-alpha) activates chaperone genes REACT:R-HSA-381183 |
| | ATF6 (ATF6-alpha) activates chaperones REACT:R-HSA-381033 |
| | ATP sensitive Potassium channels REACT:R-HSA-1296025 |
| | Attachment of GPI anchor to uPAR REACT:R-HSA-162791 |
| | Attenuation phase REACT:R-HSA-3371568 |
| | AUF1 (hnRNP D0) binds and destabilizes mRNA REACT:R-HSA-450408 |
| | AURKA Activation by TPX2 REACT:R-HSA-8854518 |
| | Autodegradation of Cdh1 by Cdh1:APC/C REACT:R-HSA-174084 |
| | Autodegradation of the E3 ubiquitin ligase COP1 REACT:R-HSA-349425 |
| | Autoimmune thyroid disease KEGG:hsa05320 |
| | Autointegration results in viral DNA circles REACT:R-HSA-177539 |
| | Autophagy - animal KEGG:hsa04140 |
| | Autophagy - other KEGG:hsa04136 |
| | AXIN missense mutants destabilize the destruction complex REACT:R-HSA-5467340 |
| | AXIN mutants destabilize the destruction complex, activating WNT signaling REACT:R-HSA-4839735 |
| | Axonal growth inhibition (RHOA activation) REACT:R-HSA-193634 |
| | Axonal growth stimulation REACT:R-HSA-209563 |
| | Axon guidance KEGG:hsa04360 |
| | Axon guidance REACT:R-HSA-422475 |
| | Bacterial invasion of epithelial cells KEGG:hsa05100 |
| | Basal cell carcinoma KEGG:hsa05217 |
| | Basal transcription factors KEGG:hsa03022 |
| | Base excision repair KEGG:hsa03410 |
| | Base Excision Repair REACT:R-HSA-73884 |
| | Base-Excision Repair, AP Site Formation REACT:R-HSA-73929 |
| | Basigin interactions REACT:R-HSA-210991 |
| | BBSome-mediated cargo-targeting to cilium REACT:R-HSA-5620922 |
| | B cell receptor signaling pathway KEGG:hsa04662 |
| | BER complex KEGG:hsa_M00296 |
| | beta-Alanine metabolism KEGG:hsa00410 |
| | Beta-catenin independent WNT signaling REACT:R-HSA-3858494 |
| | Beta-catenin phosphorylation cascade REACT:R-HSA-196299 |
| | Beta defensins REACT:R-HSA-1461957 |
| | betaKlotho-mediated ligand binding REACT:R-HSA-1307965 |
| | beta-Oxidation KEGG:hsa_M00087 |
| | beta-Oxidation, acyl-CoA synthesis KEGG:hsa_M00086 |
| | Beta oxidation of butanoyl-CoA to acetyl-CoA REACT:R-HSA-77352 |
| | Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA REACT:R-HSA-77346 |
| | Beta oxidation of hexanoyl-CoA to butanoyl-CoA REACT:R-HSA-77350 |
| | Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA REACT:R-HSA-77310 |
| | Beta oxidation of myristoyl-CoA to lauroyl-CoA REACT:R-HSA-77285 |
| | Beta oxidation of octanoyl-CoA to hexanoyl-CoA REACT:R-HSA-77348 |
| | Beta oxidation of palmitoyl-CoA to myristoyl-CoA REACT:R-HSA-77305 |
| | Beta-oxidation of pristanoyl-CoA REACT:R-HSA-389887 |
| | Beta-oxidation of very long chain fatty acids REACT:R-HSA-390247 |
| | BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members REACT:R-HSA-111453 |
| | Bicarbonate transporters REACT:R-HSA-425381 |
| | Bile acid and bile salt metabolism REACT:R-HSA-194068 |
| | Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate KEGG:hsa_M00104 |
| | Bile secretion KEGG:hsa04976 |
| | Binding and entry of HIV virion REACT:R-HSA-173107 |
| | Binding and Uptake of Ligands by Scavenger Receptors REACT:R-HSA-2173782 |
| | Binding of TCF/LEF:CTNNB1 to target gene promoters REACT:R-HSA-4411364 |
| | Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB REACT:R-HSA-141333 |
| | Biological oxidations REACT:R-HSA-211859 |
| | Biosynthesis of A2E, implicated in retinal degradation REACT:R-HSA-2466712 |
| | Biosynthesis of amino acids KEGG:hsa01230 |
| | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein REACT:R-HSA-446193 |
| | Biosynthesis of unsaturated fatty acids KEGG:hsa01040 |
| | Biotin metabolism KEGG:hsa00780 |
| | Biotin transport and metabolism REACT:R-HSA-196780 |
| | Bladder cancer KEGG:hsa05219 |
| | Bloom's syndrome complex KEGG:hsa_M00414 |
| | BMAL1:CLOCK,NPAS2 activates circadian gene expression REACT:R-HSA-1368108 |
| | BMP signaling KEGG:hsa_M00679 |
| | Branched-chain amino acid catabolism REACT:R-HSA-70895 |
| | BRCA1-associated genome surveillance complex (BASC) KEGG:hsa_M00295 |
| | Breakdown of the nuclear lamina REACT:R-HSA-352238 |
| | Breast cancer KEGG:hsa05224 |
| | Budding REACT:R-HSA-168302 |
| | Budding and maturation of HIV virion REACT:R-HSA-162588 |
| | Butanoate metabolism KEGG:hsa00650 |
| | Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA REACT:R-HSA-450385 |
| | Butyrophilin (BTN) family interactions REACT:R-HSA-8851680 |
| | B-WICH complex positively regulates rRNA expression REACT:R-HSA-5250924 |
| | C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone KEGG:hsa_M00110 |
| | C1-unit interconversion, eukaryotes KEGG:hsa_M00141 |
| | C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone KEGG:hsa_M00108 |
| | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone KEGG:hsa_M00109 |
| | C5 isoprenoid biosynthesis, mevalonate pathway KEGG:hsa_M00095 |
| | C6 deamination of adenosine REACT:R-HSA-75102 |
| | Ca2+ activated K+ channels REACT:R-HSA-1296052 |
| | Ca2+ pathway REACT:R-HSA-4086398 |
| | Ca-dependent events REACT:R-HSA-111996 |
| | Caffeine metabolism KEGG:hsa00232 |
| | Calcitonin-like ligand receptors REACT:R-HSA-419812 |
| | Calcium signaling pathway KEGG:hsa04020 |
| | Calmodulin induced events REACT:R-HSA-111933 |
| | Calnexin/calreticulin cycle REACT:R-HSA-901042 |
| | CaMK IV-mediated phosphorylation of CREB REACT:R-HSA-111932 |
| | CaM pathway REACT:R-HSA-111997 |
| | Cam-PDE 1 activation REACT:R-HSA-111957 |
| | cAMP signaling KEGG:hsa_M00695 |
| | cAMP signaling pathway KEGG:hsa04024 |
| | Cap binding complex KEGG:hsa_M00399 |
| | Cap-dependent Translation Initiation REACT:R-HSA-72737 |
| | Carbohydrate digestion and absorption KEGG:hsa04973 |
| | Carbon metabolism KEGG:hsa01200 |
| | Cardiac conduction REACT:R-HSA-5576891 |
| | Cardiac muscle contraction KEGG:hsa04260 |
| | Cargo concentration in the ER REACT:R-HSA-5694530 |
| | Cargo recognition for clathrin-mediated endocytosis REACT:R-HSA-8856825 |
| | Cargo trafficking to the periciliary membrane REACT:R-HSA-5620920 |
| | Carnitine synthesis REACT:R-HSA-71262 |
| | CASP8 activity is inhibited REACT:R-HSA-5218900 |
| | Caspase activation via extrinsic apoptotic signalling pathway REACT:R-HSA-5357769 |
| | Caspase-mediated cleavage of cytoskeletal proteins REACT:R-HSA-264870 |
| | Catabolism of glucuronate to xylulose-5-phosphate REACT:R-HSA-5661270 |
| | Catecholamine biosynthesis REACT:R-HSA-209905 |
| | Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline KEGG:hsa_M00042 |
| | Cation-coupled Chloride cotransporters REACT:R-HSA-426117 |
| | CD209 (DC-SIGN) signaling REACT:R-HSA-5621575 |
| | CD22 mediated BCR regulation REACT:R-HSA-5690714 |
| | CD28 co-stimulation REACT:R-HSA-389356 |
| | CD28 dependent PI3K/Akt signaling REACT:R-HSA-389357 |
| | CD28 dependent Vav1 pathway REACT:R-HSA-389359 |
| | Cdc20:Phospho-APC/C mediated degradation of Cyclin A REACT:R-HSA-174184 |
| | CDC6 association with the ORC:origin complex REACT:R-HSA-68689 |
| | CDK-mediated phosphorylation and removal of Cdc6 REACT:R-HSA-69017 |
| | CDO in myogenesis REACT:R-HSA-375170 |
| | CDT1 association with the CDC6:ORC:origin complex REACT:R-HSA-68827 |
| | Cell adhesion molecules (CAMs) KEGG:hsa04514 |
| | Cell-Cell communication REACT:R-HSA-1500931 |
| | Cell-cell junction organization REACT:R-HSA-421270 |
| | Cell cycle KEGG:hsa04110 |
| | Cell Cycle REACT:R-HSA-1640170 |
| | Cell Cycle Checkpoints REACT:R-HSA-69620 |
| | Cell cycle - G1/S transition KEGG:hsa_M00692 |
| | Cell cycle - G2/M transition KEGG:hsa_M00693 |
| | Cell Cycle, Mitotic REACT:R-HSA-69278 |
| | Cell death signalling via NRAGE, NRIF and NADE REACT:R-HSA-204998 |
| | Cell-extracellular matrix interactions REACT:R-HSA-446353 |
| | Cell junction organization REACT:R-HSA-446728 |
| | Cell redox homeostasis REACT:R-HSA-1222541 |
| | Cell surface interactions at the vascular wall REACT:R-HSA-202733 |
| | Cellular responses to stress REACT:R-HSA-2262752 |
| | Cellular response to heat stress REACT:R-HSA-3371556 |
| | Cellular response to hypoxia REACT:R-HSA-2262749 |
| | Cellular Senescence REACT:R-HSA-2559583 |
| | Central carbon metabolism in cancer KEGG:hsa05230 |
| | Centrosome maturation REACT:R-HSA-380287 |
| | Ceramide biosynthesis KEGG:hsa_M00094 |
| | Ceramide signalling REACT:R-HSA-193681 |
| | cGMP effects REACT:R-HSA-418457 |
| | cGMP-PKG signaling pathway KEGG:hsa04022 |
| | cGMP signaling KEGG:hsa_M00694 |
| | Chagas disease (American trypanosomiasis) KEGG:hsa05142 |
| | Chaperonin-mediated protein folding REACT:R-HSA-390466 |
| | Chemical carcinogenesis KEGG:hsa05204 |
| | Chemokine receptors bind chemokines REACT:R-HSA-380108 |
| | Chemokine signaling pathway KEGG:hsa04062 |
| | Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex REACT:R-HSA-75035 |
| | CHL1 interactions REACT:R-HSA-447041 |
| | Cholecalciferol biosynthesis KEGG:hsa_M00103 |
| | Cholesterol biosynthesis REACT:R-HSA-191273 |
| | Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol KEGG:hsa_M00101 |
| | Cholesterol biosynthesis via desmosterol REACT:R-HSA-6807047 |
| | Cholesterol biosynthesis via lathosterol REACT:R-HSA-6807062 |
| | Choline catabolism REACT:R-HSA-6798163 |
| | Choline metabolism in cancer KEGG:hsa05231 |
| | Cholinergic synapse KEGG:hsa04725 |
| | Chondroitin sulfate biosynthesis REACT:R-HSA-2022870 |
| | Chondroitin sulfate degradation KEGG:hsa_M00077 |
| | Chondroitin sulfate/dermatan sulfate metabolism REACT:R-HSA-1793185 |
| | ChREBP activates metabolic gene expression REACT:R-HSA-163765 |
| | Chromatin modifying enzymes REACT:R-HSA-3247509 |
| | Chromatin organization REACT:R-HSA-4839726 |
| | Chromosome Maintenance REACT:R-HSA-73886 |
| | Chronic myeloid leukemia KEGG:hsa05220 |
| | Chylomicron-mediated lipid transport REACT:R-HSA-174800 |
| | Cilium Assembly REACT:R-HSA-5617833 |
| | Circadian Clock REACT:R-HSA-400253 |
| | Circadian entrainment KEGG:hsa04713 |
| | Circadian rhythm KEGG:hsa04710 |
| | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate KEGG:hsa_M00010 |
| | Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate KEGG:hsa_M00011 |
| | Citrate cycle (TCA cycle) KEGG:hsa00020 |
| | Citrate cycle (TCA cycle, Krebs cycle) KEGG:hsa_M00009 |
| | Citric acid cycle (TCA cycle) REACT:R-HSA-71403 |
| | Class A/1 (Rhodopsin-like receptors) REACT:R-HSA-373076 |
| | Class B/2 (Secretin family receptors) REACT:R-HSA-373080 |
| | Class C/3 (Metabotropic glutamate/pheromone receptors) REACT:R-HSA-420499 |
| | Classical antibody-mediated complement activation REACT:R-HSA-173623 |
| | Classical Kir channels REACT:R-HSA-1296053 |
| | Class II GLUTs REACT:R-HSA-428776 |
| | Class I MHC mediated antigen processing & presentation REACT:R-HSA-983169 |
| | Clathrin derived vesicle budding REACT:R-HSA-421837 |
| | Clathrin-mediated endocytosis REACT:R-HSA-8856828 |
| | Clearance of Nuclear Envelope Membranes from Chromatin REACT:R-HSA-2993913 |
| | Cleavage of Growing Transcript in the Termination Region REACT:R-HSA-109688 |
| | Cleavage of the damaged purine REACT:R-HSA-110331 |
| | Cleavage of the damaged pyrimidine REACT:R-HSA-110329 |
| | CLEC7A (Dectin-1) induces NFAT activation REACT:R-HSA-5607763 |
| | CLEC7A (Dectin-1) signaling REACT:R-HSA-5607764 |
| | CLEC7A/inflammasome pathway REACT:R-HSA-5660668 |
| | Cobalamin (Cbl, vitamin B12) transport and metabolism REACT:R-HSA-196741 |
| | Cocaine addiction KEGG:hsa05030 |
| | Coenzyme A biosynthesis REACT:R-HSA-196783 |
| | Coenzyme A biosynthesis, pantothenate => CoA KEGG:hsa_M00120 |
| | Cohesin Loading onto Chromatin REACT:R-HSA-2470946 |
| | Collagen biosynthesis and modifying enzymes REACT:R-HSA-1650814 |
| | Collagen chain trimerization REACT:R-HSA-8948216 |
| | Collagen degradation REACT:R-HSA-1442490 |
| | Collagen formation REACT:R-HSA-1474290 |
| | Collecting duct acid secretion KEGG:hsa04966 |
| | Colorectal cancer KEGG:hsa05210 |
| | Common Pathway of Fibrin Clot Formation REACT:R-HSA-140875 |
| | Complement and coagulation cascades KEGG:hsa04610 |
| | Complement cascade REACT:R-HSA-166658 |
| | Complex I biogenesis REACT:R-HSA-6799198 |
| | Condensation of Prometaphase Chromosomes REACT:R-HSA-2514853 |
| | Condensation of Prophase Chromosomes REACT:R-HSA-2299718 |
| | Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate KEGG:hsa_M00106 |
| | Conjugation of benzoate with glycine REACT:R-HSA-177135 |
| | Conjugation of carboxylic acids REACT:R-HSA-159424 |
| | Conjugation of phenylacetate with glutamine REACT:R-HSA-177162 |
| | Conjugation of salicylate with glycine REACT:R-HSA-177128 |
| | Constitutive Signaling by Aberrant PI3K in Cancer REACT:R-HSA-2219530 |
| | Constitutive Signaling by AKT1 E17K in Cancer REACT:R-HSA-5674400 |
| | Constitutive Signaling by EGFRvIII REACT:R-HSA-5637810 |
| | Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants REACT:R-HSA-1236382 |
| | Constitutive Signaling by NOTCH1 HD Domain Mutants REACT:R-HSA-2691232 |
| | Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants REACT:R-HSA-2894862 |
| | Constitutive Signaling by NOTCH1 PEST Domain Mutants REACT:R-HSA-2644606 |
| | Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant REACT:R-HSA-2660826 |
| | Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase REACT:R-HSA-176407 |
| | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding REACT:R-HSA-6814122 |
| | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding REACT:R-HSA-389958 |
| | COPI-dependent Golgi-to-ER retrograde traffic REACT:R-HSA-6811434 |
| | COPII (Coat Protein 2) Mediated Vesicle Transport REACT:R-HSA-204005 |
| | COPII complex KEGG:hsa_M00404 |
| | COPI-independent Golgi-to-ER retrograde traffic REACT:R-HSA-6811436 |
| | COPI-mediated anterograde transport REACT:R-HSA-6807878 |
| | Costimulation by the CD28 family REACT:R-HSA-388841 |
| | COX reactions REACT:R-HSA-140180 |
| | Creatine metabolism REACT:R-HSA-71288 |
| | Creatine pathway KEGG:hsa_M00047 |
| | Creation of C4 and C2 activators REACT:R-HSA-166786 |
| | CREB phosphorylation REACT:R-HSA-199920 |
| | CREB phosphorylation through the activation of Adenylate Cyclase REACT:R-HSA-442720 |
| | CREB phosphorylation through the activation of CaMKII REACT:R-HSA-442729 |
| | CREB phosphorylation through the activation of CaMKK REACT:R-HSA-442717 |
| | CREB phosphorylation through the activation of Ras REACT:R-HSA-442742 |
| | CRMPs in Sema3A signaling REACT:R-HSA-399956 |
| | cRNA Synthesis REACT:R-HSA-192869 |
| | Crosslinking of collagen fibrils REACT:R-HSA-2243919 |
| | Cross-presentation of particulate exogenous antigens (phagosomes) REACT:R-HSA-1236973 |
| | Cross-presentation of soluble exogenous antigens (endosomes) REACT:R-HSA-1236978 |
| | CS/DS degradation REACT:R-HSA-2024101 |
| | c-src mediated regulation of Cx43 function and closure of gap junctions REACT:R-HSA-191647 |
| | CTLA4 inhibitory signaling REACT:R-HSA-389513 |
| | C-type lectin receptors (CLRs) REACT:R-HSA-5621481 |
| | Cul3-SPOP complex KEGG:hsa_M00384 |
| | Cul4-DDB1-CSA complex KEGG:hsa_M00386 |
| | Cul4-DDB1-DDB2 complex KEGG:hsa_M00385 |
| | Cyclin A/B1 associated events during G2/M transition REACT:R-HSA-69273 |
| | Cyclin A:Cdk2-associated events at S phase entry REACT:R-HSA-69656 |
| | Cyclin B2 mediated events REACT:R-HSA-157881 |
| | Cyclin D associated events in G1 REACT:R-HSA-69231 |
| | Cyclin E associated events during G1/S transition REACT:R-HSA-69202 |
| | CYP2E1 reactions REACT:R-HSA-211999 |
| | Cysteine and methionine metabolism KEGG:hsa00270 |
| | Cysteine biosynthesis, homocysteine + serine => cysteine KEGG:hsa_M00338 |
| | Cysteine formation from homocysteine REACT:R-HSA-1614603 |
| | Cytochrome bc1 complex KEGG:hsa_M00152 |
| | Cytochrome bc1 complex respiratory unit KEGG:hsa_M00151 |
| | Cytochrome c-mediated apoptotic response REACT:R-HSA-111461 |
| | Cytochrome c oxidase KEGG:hsa_M00154 |
| | Cytochrome P450 - arranged by substrate type REACT:R-HSA-211897 |
| | Cytokine-cytokine receptor interaction KEGG:hsa04060 |
| | Cytokine Signaling in Immune system REACT:R-HSA-1280215 |
| | Cytosolic DNA-sensing pathway KEGG:hsa04623 |
| | Cytosolic iron-sulfur cluster assembly REACT:R-HSA-2564830 |
| | Cytosolic sensors of pathogen-associated DNA REACT:R-HSA-1834949 |
| | Cytosolic sulfonation of small molecules REACT:R-HSA-156584 |
| | Cytosolic tRNA aminoacylation REACT:R-HSA-379716 |
| | DAG and IP3 signaling REACT:R-HSA-1489509 |
| | DAP12 interactions REACT:R-HSA-2172127 |
| | DAP12 signaling REACT:R-HSA-2424491 |
| | D-Arginine and D-ornithine metabolism KEGG:hsa00472 |
| | DARPP-32 events REACT:R-HSA-180024 |
| | DCC mediated attractive signaling REACT:R-HSA-418885 |
| | Deactivation of the beta-catenin transactivating complex REACT:R-HSA-3769402 |
| | Deadenylation-dependent mRNA decay REACT:R-HSA-429914 |
| | Deadenylation of mRNA REACT:R-HSA-429947 |
| | Death Receptor Signalling REACT:R-HSA-73887 |
| | Decapping complex KEGG:hsa_M00395 |
| | Dectin-1 mediated noncanonical NF-kB signaling REACT:R-HSA-5607761 |
| | Dectin-2 family REACT:R-HSA-5621480 |
| | Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B REACT:R-HSA-5682294 |
| | Defective ABCA1 causes Tangier disease REACT:R-HSA-5682113 |
| | Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3) REACT:R-HSA-5688399 |
| | Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3) REACT:R-HSA-5683678 |
| | Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2 REACT:R-HSA-5678520 |
| | Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1 REACT:R-HSA-5678771 |
| | Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7) REACT:R-HSA-5683371 |
| | Defective ABCC2 causes Dubin-Johnson syndrome REACT:R-HSA-5679001 |
| | Defective ABCC6 causes pseudoxanthoma elasticum (PXE) REACT:R-HSA-5690338 |
| | Defective ABCC8 can cause hypoglycemias and hyperglycemias REACT:R-HSA-5683177 |
| | Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia REACT:R-HSA-5678420 |
| | Defective ABCD1 causes adrenoleukodystrophy (ALD) REACT:R-HSA-5684045 |
| | Defective ABCD4 causes methylmalonic aciduria and homocystinuria, cblj type (MAHCJ) REACT:R-HSA-5683329 |
| | Defective ABCG5 causes sitosterolemia REACT:R-HSA-5679096 |
| | Defective ABCG8 causes gallbladder disease 4 and sitosterolemia REACT:R-HSA-5679090 |
| | Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) REACT:R-HSA-5579031 |
| | Defective ACY1 causes encephalopathy REACT:R-HSA-5579007 |
| | Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) REACT:R-HSA-5578997 |
| | Defective ALG11 causes ALG11-CDG (CDG-1p) REACT:R-HSA-4551295 |
| | Defective ALG12 causes ALG12-CDG (CDG-1g) REACT:R-HSA-4720489 |
| | Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) REACT:R-HSA-5633231 |
| | Defective ALG1 causes ALG1-CDG (CDG-1k) REACT:R-HSA-4549380 |
| | Defective ALG2 causes ALG2-CDG (CDG-1i) REACT:R-HSA-4549349 |
| | Defective ALG3 causes ALG3-CDG (CDG-1d) REACT:R-HSA-4720475 |
| | Defective ALG6 causes ALG6-CDG (CDG-1c) REACT:R-HSA-4724289 |
| | Defective ALG8 causes ALG8-CDG (CDG-1h) REACT:R-HSA-4724325 |
| | Defective ALG9 causes ALG9-CDG (CDG-1l) REACT:R-HSA-4720454 |
| | Defective AMN causes hereditary megaloblastic anemia 1 REACT:R-HSA-3359462 |
| | Defective AVP causes neurohypophyseal diabetes insipidus (NDI) REACT:R-HSA-5619099 |
| | Defective B3GALT6 causes EDSP2 and SEMDJL1 REACT:R-HSA-4420332 |
| | Defective B3GALTL causes Peters-plus syndrome (PpS) REACT:R-HSA-5083635 |
| | Defective B3GAT3 causes JDSSDHD REACT:R-HSA-3560801 |
| | Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) REACT:R-HSA-3656244 |
| | Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) REACT:R-HSA-4793953 |
| | Defective B4GALT7 causes EDS, progeroid type REACT:R-HSA-3560783 |
| | Defective BTD causes biotidinase deficiency REACT:R-HSA-3371598 |
| | Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) REACT:R-HSA-5083632 |
| | Defective CD320 causes methylmalonic aciduria REACT:R-HSA-3359485 |
| | Defective CFTR causes cystic fibrosis REACT:R-HSA-5678895 |
| | Defective CHST14 causes EDS, musculocontractural type REACT:R-HSA-3595174 |
| | Defective CHST3 causes SEDCJD REACT:R-HSA-3595172 |
| | Defective CHST6 causes MCDC1 REACT:R-HSA-3656225 |
| | Defective CHSY1 causes TPBS REACT:R-HSA-3595177 |
| | Defective CP causes aceruloplasminemia (ACERULOP) REACT:R-HSA-5619060 |
| | Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) REACT:R-HSA-5688890 |
| | Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) REACT:R-HSA-5688849 |
| | Defective CUBN causes hereditary megaloblastic anemia 1 REACT:R-HSA-3359463 |
| | Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) REACT:R-HSA-5579026 |
| | Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) REACT:R-HSA-5579017 |
| | Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) REACT:R-HSA-5579009 |
| | Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) REACT:R-HSA-5579028 |
| | Defective CYP19A1 causes Aromatase excess syndrome (AEXS) REACT:R-HSA-5579030 |
| | Defective CYP1B1 causes Glaucoma REACT:R-HSA-5579000 |
| | Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) REACT:R-HSA-5579021 |
| | Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) REACT:R-HSA-5579010 |
| | Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) REACT:R-HSA-5579015 |
| | Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) REACT:R-HSA-5579004 |
| | Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) REACT:R-HSA-5578996 |
| | Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) REACT:R-HSA-5579014 |
| | Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) REACT:R-HSA-5579027 |
| | Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) REACT:R-HSA-5579011 |
| | Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) REACT:R-HSA-5579005 |
| | Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) REACT:R-HSA-5579013 |
| | Defective DHDDS causes retinitis pigmentosa 59 REACT:R-HSA-4755609 |
| | Defective DOLK causes DOLK-CDG (CDG-1m) REACT:R-HSA-4755583 |
| | Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 REACT:R-HSA-4549356 |
| | Defective DPM1 causes DPM1-CDG (CDG-1e) REACT:R-HSA-4717374 |
| | Defective DPM2 causes DPM2-CDG (CDG-1u) REACT:R-HSA-4719377 |
| | Defective DPM3 causes DPM3-CDG (CDG-1o) REACT:R-HSA-4719360 |
| | Defective EXT1 causes exostoses 1, TRPS2 and CHDS REACT:R-HSA-3656253 |
| | Defective EXT2 causes exostoses 2 REACT:R-HSA-3656237 |
| | Defective FMO3 causes Trimethylaminuria (TMAU) REACT:R-HSA-5579019 |
| | Defective GALE can cause Epimerase-deficiency galactosemia (EDG) REACT:R-HSA-5609977 |
| | Defective GALK1 can cause Galactosemia II (GALCT2) REACT:R-HSA-5609976 |
| | Defective GALNT12 causes colorectal cancer 1 (CRCS1) REACT:R-HSA-5083636 |
| | Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) REACT:R-HSA-5083625 |
| | Defective GALT can cause Galactosemia REACT:R-HSA-5609978 |
| | Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) REACT:R-HSA-5619073 |
| | Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) REACT:R-HSA-5578999 |
| | Defective GFPT1 causes CMSTA1 REACT:R-HSA-4085023 |
| | Defective GGT1 causes Glutathionuria (GLUTH) REACT:R-HSA-5579022 |
| | Defective GIF causes intrinsic factor deficiency REACT:R-HSA-3359457 |
| | Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2 REACT:R-HSA-4085011 |
| | Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) REACT:R-HSA-5579006 |
| | Defective HK1 causes hexokinase deficiency (HK deficiency) REACT:R-HSA-5619056 |
| | Defective HLCS causes multiple carboxylase deficiency REACT:R-HSA-3371599 |
| | Defective LARGE causes MDDGA6 and MDDGB6 REACT:R-HSA-5083627 |
| | Defective LFNG causes SCDO3 REACT:R-HSA-5083630 |
| | Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF REACT:R-HSA-3359458 |
| | Defective MAN1B1 causes MRT15 REACT:R-HSA-4793950 |
| | Defective MAOA causes Brunner syndrome (BRUNS) REACT:R-HSA-5579012 |
| | Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) REACT:R-HSA-5579024 |
| | Defective MGAT2 causes MGAT2-CDG (CDG-2a) REACT:R-HSA-4793952 |
| | Defective MMAA causes methylmalonic aciduria type cblA REACT:R-HSA-3359475 |
| | Defective MMAB causes methylmalonic aciduria type cblB REACT:R-HSA-3359471 |
| | Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC REACT:R-HSA-3359474 |
| | Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD REACT:R-HSA-3359473 |
| | Defective MOGS causes MOGS-CDG (CDG-2b) REACT:R-HSA-4793954 |
| | Defective MPDU1 causes MPDU1-CDG (CDG-1f) REACT:R-HSA-4687000 |
| | Defective MPI causes MPI-CDG (CDG-1b) REACT:R-HSA-4043916 |
| | Defective MTR causes methylmalonic aciduria and homocystinuria type cblG REACT:R-HSA-3359469 |
| | Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE REACT:R-HSA-3359467 |
| | Defective MUT causes methylmalonic aciduria mut type REACT:R-HSA-3359478 |
| | Defective NEU1 causes sialidosis REACT:R-HSA-4341670 |
| | Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) REACT:R-HSA-5578998 |
| | Defective PAPSS2 causes SEMD-PA REACT:R-HSA-3560796 |
| | Defective PGM1 causes PGM1-CDG (CDG1t) REACT:R-HSA-5609974 |
| | Defective PMM2 causes PMM2-CDG (CDG-1a) REACT:R-HSA-4043911 |
| | Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 REACT:R-HSA-5083628 |
| | Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 REACT:R-HSA-5083633 |
| | Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 REACT:R-HSA-5083629 |
| | Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS) REACT:R-HSA-5688031 |
| | Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) REACT:R-HSA-5688354 |
| | Defective RFT1 causes RFT1-CDG (CDG-1n) REACT:R-HSA-4570571 |
| | Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN) REACT:R-HSA-5619042 |
| | Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF) REACT:R-HSA-5687868 |
| | Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) REACT:R-HSA-5619048 |
| | Defective SLC12A1 causes Bartter syndrome 1 (BS1) REACT:R-HSA-5619104 |
| | Defective SLC12A3 causes Gitelman syndrome (GS) REACT:R-HSA-5619087 |
| | Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) REACT:R-HSA-5619039 |
| | Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) REACT:R-HSA-5619070 |
| | Defective SLC17A5 causes Salla disease (SD) and ISSD REACT:R-HSA-5619035 |
| | Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25) REACT:R-HSA-5619076 |
| | Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) REACT:R-HSA-5619067 |
| | Defective SLC1A3 causes episodic ataxia 6 (EA6) REACT:R-HSA-5619062 |
| | Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) REACT:R-HSA-5619111 |
| | Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) REACT:R-HSA-5619071 |
| | Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1) REACT:R-HSA-5619066 |
| | Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) REACT:R-HSA-5619053 |
| | Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) REACT:R-HSA-5619077 |
| | Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) REACT:R-HSA-5619055 |
| | Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6) REACT:R-HSA-5619036 |
| | Defective SLC26A2 causes chondrodysplasias REACT:R-HSA-3560792 |
| | Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1) REACT:R-HSA-5619085 |
| | Defective SLC26A4 causes Pendred syndrome (PDS) REACT:R-HSA-5619046 |
| | Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) REACT:R-HSA-5619108 |
| | Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS) REACT:R-HSA-5619063 |
| | Defective SLC2A10 causes arterial tortuosity syndrome (ATS) REACT:R-HSA-5619068 |
| | Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) REACT:R-HSA-5619043 |
| | Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS) REACT:R-HSA-5619098 |
| | Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) REACT:R-HSA-5619047 |
| | Defective SLC33A1 causes spastic paraplegia 42 (SPG42) REACT:R-HSA-5619061 |
| | Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) REACT:R-HSA-5619040 |
| | Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) REACT:R-HSA-5619045 |
| | Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) REACT:R-HSA-5687583 |
| | Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) REACT:R-HSA-5619097 |
| | Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) REACT:R-HSA-5619037 |
| | Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) REACT:R-HSA-5663020 |
| | Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) REACT:R-HSA-5619072 |
| | Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) REACT:R-HSA-5619083 |
| | Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C) REACT:R-HSA-5619078 |
| | Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) REACT:R-HSA-5579020 |
| | Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG) REACT:R-HSA-5619041 |
| | Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ) REACT:R-HSA-5619088 |
| | Defective SLC3A1 causes cystinuria (CSNU) REACT:R-HSA-5619113 |
| | Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) REACT:R-HSA-5655799 |
| | Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) REACT:R-HSA-5619049 |
| | Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) REACT:R-HSA-5619050 |
| | Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) REACT:R-HSA-5619054 |
| | Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) REACT:R-HSA-5656364 |
| | Defective SLC5A2 causes renal glucosuria (GLYS1) REACT:R-HSA-5658208 |
| | Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) REACT:R-HSA-5619096 |
| | Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) REACT:R-HSA-5619114 |
| | Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) REACT:R-HSA-5658471 |
| | Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria REACT:R-HSA-5619079 |
| | Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria REACT:R-HSA-5659729 |
| | Defective SLC6A19 causes Hartnup disorder (HND) REACT:R-HSA-5619044 |
| | Defective SLC6A19 causes Hartnup disorder (HND) REACT:R-HSA-5659735 |
| | Defective SLC6A2 causes orthostatic intolerance (OI) REACT:R-HSA-5619109 |
| | Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) REACT:R-HSA-5619081 |
| | Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) REACT:R-HSA-5660724 |
| | Defective SLC6A5 causes hyperekplexia 3 (HKPX3) REACT:R-HSA-5619089 |
| | Defective SLC7A7 causes lysinuric protein intolerance (LPI) REACT:R-HSA-5660862 |
| | Defective SLC7A9 causes cystinuria (CSNU) REACT:R-HSA-5660883 |
| | Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) REACT:R-HSA-5619092 |
| | Defective SLC9A9 causes autism 16 (AUTS16) REACT:R-HSA-5619052 |
| | Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5619110 |
| | Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5661182 |
| | Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5619058 |
| | Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) REACT:R-HSA-5619095 |
| | Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ REACT:R-HSA-4755579 |
| | Defective ST3GAL3 causes MCT12 and EIEE15 REACT:R-HSA-3656243 |
| | Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) REACT:R-HSA-5579032 |
| | Defective TCN2 causes hereditary megaloblastic anemia REACT:R-HSA-3359454 |
| | Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) REACT:R-HSA-5578995 |
| | Defective TRP may confer susceptibility towards thyroid papillary carcinoma (TPC) REACT:R-HSA-5619107 |
| | Defective UGT1A1 causes hyperbilirubinemia REACT:R-HSA-5579002 |
| | Defective UGT1A4 causes hyperbilirubinemia REACT:R-HSA-5579016 |
| | Defects in biotin (Btn) metabolism REACT:R-HSA-3323169 |
| | Defects in cobalamin (B12) metabolism REACT:R-HSA-3296469 |
| | Defects in vitamin and cofactor metabolism REACT:R-HSA-3296482 |
| | Defensins REACT:R-HSA-1461973 |
| | Degradation of AXIN REACT:R-HSA-4641257 |
| | Degradation of beta-catenin by the destruction complex REACT:R-HSA-195253 |
| | Degradation of cysteine and homocysteine REACT:R-HSA-1614558 |
| | Degradation of DVL REACT:R-HSA-4641258 |
| | Degradation of GABA REACT:R-HSA-916853 |
| | Degradation of GLI1 by the proteasome REACT:R-HSA-5610780 |
| | Degradation of GLI2 by the proteasome REACT:R-HSA-5610783 |
| | Degradation of the extracellular matrix REACT:R-HSA-1474228 |
| | Deletions in the AMER1 gene destabilize the destruction complex REACT:R-HSA-5467343 |
| | Deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling REACT:R-HSA-5467345 |
| | Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels REACT:R-HSA-112308 |
| | Depolymerisation of the Nuclear Lamina REACT:R-HSA-4419969 |
| | Deposition of new CENPA-containing nucleosomes at the centromere REACT:R-HSA-606279 |
| | Depurination REACT:R-HSA-73927 |
| | Depyrimidination REACT:R-HSA-73928 |
| | Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models REACT:R-HSA-8862803 |
| | Dermatan sulfate biosynthesis REACT:R-HSA-2022923 |
| | Dermatan sulfate degradation KEGG:hsa_M00076 |
| | Detoxification of Reactive Oxygen Species REACT:R-HSA-3299685 |
| | Deubiquitination REACT:R-HSA-5688426 |
| | Developmental Biology REACT:R-HSA-1266738 |
| | DEx/H-box helicases activate type I IFN and inflammatory cytokines production REACT:R-HSA-3134963 |
| | D-Glutamine and D-glutamate metabolism KEGG:hsa00471 |
| | Digestion of dietary carbohydrate REACT:R-HSA-189085 |
| | Digestion of dietary lipid REACT:R-HSA-192456 |
| | Dilated cardiomyopathy KEGG:hsa05414 |
| | Dimerization of procaspase-8 REACT:R-HSA-69416 |
| | Disassembly of the destruction complex and recruitment of AXIN to the membrane REACT:R-HSA-4641262 |
| | Disease REACT:R-HSA-1643685 |
| | Diseases associated with glycosaminoglycan metabolism REACT:R-HSA-3560782 |
| | Diseases associated with glycosylation precursor biosynthesis REACT:R-HSA-5609975 |
| | Diseases associated with N-glycosylation of proteins REACT:R-HSA-3781860 |
| | Diseases associated with O-glycosylation of proteins REACT:R-HSA-3906995 |
| | Diseases associated with surfactant metabolism REACT:R-HSA-5687613 |
| | Diseases associated with the TLR signaling cascade REACT:R-HSA-5602358 |
| | Diseases associated with visual transduction REACT:R-HSA-2474795 |
| | Diseases of carbohydrate metabolism REACT:R-HSA-5663084 |
| | Diseases of glycosylation REACT:R-HSA-3781865 |
| | Diseases of Immune System REACT:R-HSA-5260271 |
| | Diseases of metabolism REACT:R-HSA-5668914 |
| | Diseases of signal transduction REACT:R-HSA-5663202 |
| | Disinhibition of SNARE formation REACT:R-HSA-114516 |
| | Disorders of transmembrane transporters REACT:R-HSA-5619115 |
| | Displacement of DNA glycosylase by APEX1 REACT:R-HSA-110357 |
| | Dissolution of Fibrin Clot REACT:R-HSA-75205 |
| | DNA Damage Bypass REACT:R-HSA-73893 |
| | DNA damage-induced cell cycle checkpoints KEGG:hsa_M00691 |
| | DNA Damage Recognition in GG-NER REACT:R-HSA-5696394 |
| | DNA Damage Reversal REACT:R-HSA-73942 |
| | DNA Damage/Telomere Stress Induced Senescence REACT:R-HSA-2559586 |
| | DNA Double-Strand Break Repair REACT:R-HSA-5693532 |
| | DNA Double Strand Break Response REACT:R-HSA-5693606 |
| | DNA methylation REACT:R-HSA-5334118 |
| | DNA-PK complex KEGG:hsa_M00297 |
| | DNA polymerase alpha / primase complex KEGG:hsa_M00261 |
| | DNA polymerase delta complex KEGG:hsa_M00262 |
| | DNA polymerase epsilon complex KEGG:hsa_M00263 |
| | DNA polymerase gamma complex KEGG:hsa_M00294 |
| | DNA polymerase zeta complex KEGG:hsa_M00293 |
| | DNA Repair REACT:R-HSA-73894 |
| | DNA replication KEGG:hsa03030 |
| | DNA Replication REACT:R-HSA-69306 |
| | DNA replication initiation REACT:R-HSA-68952 |
| | DNA Replication Pre-Initiation REACT:R-HSA-69002 |
| | DNA strand elongation REACT:R-HSA-69190 |
| | Dopamine clearance from the synaptic cleft REACT:R-HSA-379401 |
| | Dopamine Neurotransmitter Release Cycle REACT:R-HSA-212676 |
| | Dopamine receptors REACT:R-HSA-390651 |
| | Dopaminergic synapse KEGG:hsa04728 |
| | Dorso-ventral axis formation KEGG:hsa04320 |
| | Downregulation of ERBB2:ERBB3 signaling REACT:R-HSA-1358803 |
| | Downregulation of ERBB2 signaling REACT:R-HSA-8863795 |
| | Downregulation of ERBB4 signaling REACT:R-HSA-1253288 |
| | Downregulation of SMAD2/3:SMAD4 transcriptional activity REACT:R-HSA-2173795 |
| | Downregulation of TGF-beta receptor signaling REACT:R-HSA-2173788 |
| | Downstream signaling events of B Cell Receptor (BCR) REACT:R-HSA-1168372 |
| | Downstream signaling of activated FGFR1 REACT:R-HSA-5654687 |
| | Downstream signaling of activated FGFR2 REACT:R-HSA-5654696 |
| | Downstream signaling of activated FGFR3 REACT:R-HSA-5654708 |
| | Downstream signaling of activated FGFR4 REACT:R-HSA-5654716 |
| | Downstream signal transduction REACT:R-HSA-186763 |
| | Downstream TCR signaling REACT:R-HSA-202424 |
| | Drug metabolism - cytochrome P450 KEGG:hsa00982 |
| | Drug metabolism - other enzymes KEGG:hsa00983 |
| | DSCAM interactions REACT:R-HSA-376172 |
| | Dual Incision in GG-NER REACT:R-HSA-5696400 |
| | Dual incision in TC-NER REACT:R-HSA-6782135 |
| | E2F-enabled inhibition of pre-replication complex formation REACT:R-HSA-113507 |
| | E2F mediated regulation of DNA replication REACT:R-HSA-113510 |
| | E3 ubiquitin ligases ubiquitinate target proteins REACT:R-HSA-8866654 |
| | Early Phase of HIV Life Cycle REACT:R-HSA-162594 |
| | ECM proteoglycans REACT:R-HSA-3000178 |
| | ECM-receptor interaction KEGG:hsa04512 |
| | ECS complex KEGG:hsa_M00388 |
| | ECV complex KEGG:hsa_M00383 |
| | Effects of PIP2 hydrolysis REACT:R-HSA-114508 |
| | EGFR downregulation REACT:R-HSA-182971 |
| | EGFR interacts with phospholipase C-gamma REACT:R-HSA-212718 |
| | EGFR Transactivation by Gastrin REACT:R-HSA-2179392 |
| | EGFR tyrosine kinase inhibitor resistance KEGG:hsa01521 |
| | Eicosanoid ligand-binding receptors REACT:R-HSA-391903 |
| | Eicosanoids REACT:R-HSA-211979 |
| | eIF4F complex KEGG:hsa_M00428 |
| | Elastic fibre formation REACT:R-HSA-1566948 |
| | Electric Transmission Across Gap Junctions REACT:R-HSA-112303 |
| | Electron transport from NADPH to Ferredoxin REACT:R-HSA-2395516 |
| | Elevation of cytosolic Ca2+ levels REACT:R-HSA-139853 |
| | Endocrine and other factor-regulated calcium reabsorption KEGG:hsa04961 |
| | Endocrine resistance KEGG:hsa01522 |
| | Endocytosis KEGG:hsa04144 |
| | Endogenous sterols REACT:R-HSA-211976 |
| | Endometrial cancer KEGG:hsa05213 |
| | Endosomal Sorting Complex Required For Transport (ESCRT) REACT:R-HSA-917729 |
| | Endosomal/Vacuolar pathway REACT:R-HSA-1236977 |
| | Energy dependent regulation of mTOR by LKB1-AMPK REACT:R-HSA-380972 |
| | eNOS activation REACT:R-HSA-203615 |
| | eNOS activation and regulation REACT:R-HSA-203765 |
| | Entry of Influenza Virion into Host Cell via Endocytosis REACT:R-HSA-168275 |
| | Enzymatic degradation of dopamine by COMT REACT:R-HSA-379397 |
| | Enzymatic degradation of Dopamine by monoamine oxidase REACT:R-HSA-379398 |
| | EPHA-mediated growth cone collapse REACT:R-HSA-3928663 |
| | EPHB-mediated forward signaling REACT:R-HSA-3928662 |
| | EPH-ephrin mediated repulsion of cells REACT:R-HSA-3928665 |
| | EPH-Ephrin signaling REACT:R-HSA-2682334 |
| | Ephrin signaling REACT:R-HSA-3928664 |
| | Epigenetic regulation of gene expression REACT:R-HSA-212165 |
| | Epithelial cell signaling in Helicobacter pylori infection KEGG:hsa05120 |
| | Epstein-Barr virus infection KEGG:hsa05169 |
| | ERBB2 Activates PTK6 Signaling REACT:R-HSA-8847993 |
| | ERBB2 Regulates Cell Motility REACT:R-HSA-6785631 |
| | ErbB signaling pathway KEGG:hsa04012 |
| | ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression REACT:R-HSA-427389 |
| | ERK/MAPK targets REACT:R-HSA-198753 |
| | ERKs are inactivated REACT:R-HSA-202670 |
| | ER-Phagosome pathway REACT:R-HSA-1236974 |
| | ER Quality Control Compartment (ERQC) REACT:R-HSA-901032 |
| | ER to Golgi Anterograde Transport REACT:R-HSA-199977 |
| | Erythrocytes take up carbon dioxide and release oxygen REACT:R-HSA-1237044 |
| | Erythrocytes take up oxygen and release carbon dioxide REACT:R-HSA-1247673 |
| | ESCRT-0 complex KEGG:hsa_M00408 |
| | ESCRT-I complex KEGG:hsa_M00409 |
| | ESCRT-II complex KEGG:hsa_M00410 |
| | ESCRT-III complex KEGG:hsa_M00412 |
| | Essential fructosuria REACT:R-HSA-5657562 |
| | Essential pentosuria REACT:R-HSA-5662853 |
| | Establishment of Sister Chromatid Cohesion REACT:R-HSA-2468052 |
| | Estrogen biosynthesis REACT:R-HSA-193144 |
| | Estrogen signaling pathway KEGG:hsa04915 |
| | Ethanol oxidation REACT:R-HSA-71384 |
| | Ether lipid metabolism KEGG:hsa00565 |
| | Eukaryotic Translation Elongation REACT:R-HSA-156842 |
| | Eukaryotic Translation Initiation REACT:R-HSA-72613 |
| | Eukaryotic Translation Termination REACT:R-HSA-72764 |
| | Exon junction complex (EJC) KEGG:hsa_M00430 |
| | Exosome, archaea KEGG:hsa_M00390 |
| | Exosome, eukaryotes KEGG:hsa_M00391 |
| | Export of Viral Ribonucleoproteins from Nucleus REACT:R-HSA-168274 |
| | Extension of Telomeres REACT:R-HSA-180786 |
| | Extracellular matrix organization REACT:R-HSA-1474244 |
| | Extrinsic Pathway of Fibrin Clot Formation REACT:R-HSA-140834 |
| | Facilitative Na+-independent glucose transporters REACT:R-HSA-428790 |
| | FA core complex KEGG:hsa_M00413 |
| | Factors involved in megakaryocyte development and platelet production REACT:R-HSA-983231 |
| | Fanconi anemia pathway KEGG:hsa03460 |
| | Fanconi Anemia Pathway REACT:R-HSA-6783310 |
| | FasL/ CD95L signaling REACT:R-HSA-75157 |
| | Fat digestion and absorption KEGG:hsa04975 |
| | Fatty acid biosynthesis KEGG:hsa00061 |
| | Fatty acid biosynthesis, elongation KEGG:hsa_M00083 |
| | Fatty acid biosynthesis, elongation, endoplasmic reticulum KEGG:hsa_M00415 |
| | Fatty acid biosynthesis, elongation, mitochondria KEGG:hsa_M00085 |
| | Fatty acid biosynthesis, initiation KEGG:hsa_M00082 |
| | Fatty acid degradation KEGG:hsa00071 |
| | Fatty acid elongation KEGG:hsa00062 |
| | Fatty acid metabolism KEGG:hsa01212 |
| | Fatty acids REACT:R-HSA-211935 |
| | Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion REACT:R-HSA-434316 |
| | Fatty acid, triacylglycerol, and ketone body metabolism REACT:R-HSA-535734 |
| | Fatty Acyl-CoA Biosynthesis REACT:R-HSA-75105 |
| | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis REACT:R-HSA-8854050 |
| | FBXW7 Mutants and NOTCH1 in Cancer REACT:R-HSA-2644605 |
| | Fc epsilon receptor (FCERI) signaling REACT:R-HSA-2454202 |
| | Fc epsilon RI signaling pathway KEGG:hsa04664 |
| | FCERI mediated Ca+2 mobilization REACT:R-HSA-2871809 |
| | FCERI mediated MAPK activation REACT:R-HSA-2871796 |
| | FCERI mediated NF-kB activation REACT:R-HSA-2871837 |
| | Fcgamma receptor (FCGR) dependent phagocytosis REACT:R-HSA-2029480 |
| | Fc gamma R-mediated phagocytosis KEGG:hsa04666 |
| | FCGR activation REACT:R-HSA-2029481 |
| | Ferroptosis KEGG:hsa04216 |
| | Fertilization REACT:R-HSA-1187000 |
| | FGFR1b ligand binding and activation REACT:R-HSA-190370 |
| | FGFR1c and Klotho ligand binding and activation REACT:R-HSA-190374 |
| | FGFR1c ligand binding and activation REACT:R-HSA-190373 |
| | FGFR1 ligand binding and activation REACT:R-HSA-190242 |
| | FGFR1 mutant receptor activation REACT:R-HSA-1839124 |
| | FGFR2 alternative splicing REACT:R-HSA-6803529 |
| | FGFR2b ligand binding and activation REACT:R-HSA-190377 |
| | FGFR2c ligand binding and activation REACT:R-HSA-190375 |
| | FGFR2 ligand binding and activation REACT:R-HSA-190241 |
| | FGFR2 mutant receptor activation REACT:R-HSA-1839126 |
| | FGFR3b ligand binding and activation REACT:R-HSA-190371 |
| | FGFR3c ligand binding and activation REACT:R-HSA-190372 |
| | FGFR3 ligand binding and activation REACT:R-HSA-190239 |
| | FGFR3 mutant receptor activation REACT:R-HSA-2033514 |
| | FGFR4 ligand binding and activation REACT:R-HSA-190322 |
| | FGFR4 mutant receptor activation REACT:R-HSA-1839128 |
| | FGFRL1 modulation of FGFR1 signaling REACT:R-HSA-5658623 |
| | Fibronectin matrix formation REACT:R-HSA-1566977 |
| | Ficolins bind to repetitive carbohydrate structures on the target cell surface REACT:R-HSA-2855086 |
| | Fluid shear stress and atherosclerosis KEGG:hsa05418 |
| | FMO oxidises nucleophiles REACT:R-HSA-217271 |
| | Focal adhesion KEGG:hsa04510 |
| | Folate biosynthesis KEGG:hsa00790 |
| | Folding of actin by CCT/TriC REACT:R-HSA-390450 |
| | Formation of annular gap junctions REACT:R-HSA-196025 |
| | Formation of a pool of free 40S subunits REACT:R-HSA-72689 |
| | Formation of apoptosome REACT:R-HSA-111458 |
| | Formation of ATP by chemiosmotic coupling REACT:R-HSA-163210 |
| | Formation of editosomes by ADAR proteins REACT:R-HSA-77042 |
| | Formation of Fibrin Clot (Clotting Cascade) REACT:R-HSA-140877 |
| | Formation of HIV-1 elongation complex containing HIV-1 Tat REACT:R-HSA-167200 |
| | Formation of HIV elongation complex in the absence of HIV Tat REACT:R-HSA-167152 |
| | Formation of Incision Complex in GG-NER REACT:R-HSA-5696395 |
| | Formation of RNA Pol II elongation complex REACT:R-HSA-112382 |
| | Formation of selenosugars for excretion REACT:R-HSA-2408499 |
| | Formation of Senescence-Associated Heterochromatin Foci (SAHF) REACT:R-HSA-2559584 |
| | Formation of TC-NER Pre-Incision Complex REACT:R-HSA-6781823 |
| | Formation of the active cofactor, UDP-glucuronate REACT:R-HSA-173599 |
| | Formation of the beta-catenin:TCF transactivating complex REACT:R-HSA-201722 |
| | Formation of the cornified envelope REACT:R-HSA-6809371 |
| | Formation of the Early Elongation Complex REACT:R-HSA-113418 |
| | Formation of the Editosome REACT:R-HSA-75094 |
| | Formation of the HIV-1 Early Elongation Complex REACT:R-HSA-167158 |
| | Formation of the ternary complex, and subsequently, the 43S complex REACT:R-HSA-72695 |
| | Formation of tubulin folding intermediates by CCT/TriC REACT:R-HSA-389960 |
| | Formyl peptide receptors bind formyl peptides and many other ligands REACT:R-HSA-444473 |
| | FoxO signaling pathway KEGG:hsa04068 |
| | Free fatty acid receptors REACT:R-HSA-444209 |
| | Free fatty acids regulate insulin secretion REACT:R-HSA-400451 |
| | Frs2-mediated activation REACT:R-HSA-170968 |
| | FRS-mediated FGFR1 signaling REACT:R-HSA-5654693 |
| | FRS-mediated FGFR2 signaling REACT:R-HSA-5654700 |
| | FRS-mediated FGFR3 signaling REACT:R-HSA-5654706 |
| | FRS-mediated FGFR4 signaling REACT:R-HSA-5654712 |
| | Fructose and mannose metabolism KEGG:hsa00051 |
| | Fructose biosynthesis REACT:R-HSA-5652227 |
| | Fructose catabolism REACT:R-HSA-70350 |
| | Fructose metabolism REACT:R-HSA-5652084 |
| | F-type ATPase, eukaryotes KEGG:hsa_M00158 |
| | Fusion and Uncoating of the Influenza Virion REACT:R-HSA-168270 |
| | Fusion of the Influenza Virion to the Host Cell Endosome REACT:R-HSA-168288 |
| | G0 and Early G1 REACT:R-HSA-1538133 |
| | G1 Phase REACT:R-HSA-69236 |
| | G1/S DNA Damage Checkpoints REACT:R-HSA-69615 |
| | G1/S-Specific Transcription REACT:R-HSA-69205 |
| | G1/S Transition REACT:R-HSA-69206 |
| | G2/M Checkpoints REACT:R-HSA-69481 |
| | G2/M DNA damage checkpoint REACT:R-HSA-69473 |
| | G2/M DNA replication checkpoint REACT:R-HSA-69478 |
| | G2/M Transition REACT:R-HSA-69275 |
| | G2 Phase REACT:R-HSA-68911 |
| | GAB1 signalosome REACT:R-HSA-180292 |
| | GABA A receptor activation REACT:R-HSA-977441 |
| | GABA A (rho) receptor activation REACT:R-HSA-977442 |
| | GABA biosynthesis, eukaryotes, putrescine => GABA KEGG:hsa_M00135 |
| | GABA B receptor activation REACT:R-HSA-977444 |
| | GABAergic synapse KEGG:hsa04727 |
| | GABA (gamma-Aminobutyrate) shunt KEGG:hsa_M00027 |
| | GABA receptor activation REACT:R-HSA-977443 |
| | GABA synthesis REACT:R-HSA-888568 |
| | GABA synthesis, release, reuptake and degradation REACT:R-HSA-888590 |
| | Galactose catabolism REACT:R-HSA-70370 |
| | Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P KEGG:hsa_M00632 |
| | Galactose metabolism KEGG:hsa00052 |
| | G alpha (12/13) signalling events REACT:R-HSA-416482 |
| | G alpha (i) signalling events REACT:R-HSA-418594 |
| | G alpha (q) signalling events REACT:R-HSA-416476 |
| | G alpha (s) signalling events REACT:R-HSA-418555 |
| | G alpha (z) signalling events REACT:R-HSA-418597 |
| | Gamma carboxylation, hypusine formation and arylsulfatase activation REACT:R-HSA-163841 |
| | Gamma-carboxylation of protein precursors REACT:R-HSA-159740 |
| | Gamma-carboxylation, transport, and amino-terminal cleavage of proteins REACT:R-HSA-159854 |
| | Gap-filling DNA repair synthesis and ligation in GG-NER REACT:R-HSA-5696397 |
| | Gap-filling DNA repair synthesis and ligation in TC-NER REACT:R-HSA-6782210 |
| | Gap junction KEGG:hsa04540 |
| | Gap junction assembly REACT:R-HSA-190861 |
| | Gap junction degradation REACT:R-HSA-190873 |
| | Gap junction trafficking REACT:R-HSA-190828 |
| | Gap junction trafficking and regulation REACT:R-HSA-157858 |
| | Gastric acid secretion KEGG:hsa04971 |
| | Gastrin-CREB signalling pathway via PKC and MAPK REACT:R-HSA-881907 |
| | G beta:gamma signalling through PI3Kgamma REACT:R-HSA-392451 |
| | G beta:gamma signalling through PLC beta REACT:R-HSA-418217 |
| | GDP-fucose biosynthesis REACT:R-HSA-6787639 |
| | Gene Expression REACT:R-HSA-74160 |
| | Generation of second messenger molecules REACT:R-HSA-202433 |
| | Generic Transcription Pathway REACT:R-HSA-212436 |
| | Gene Silencing by RNA REACT:R-HSA-211000 |
| | GINS complex KEGG:hsa_M00286 |
| | GLI3 is processed to GLI3R by the proteasome REACT:R-HSA-5610785 |
| | Glioma KEGG:hsa05214 |
| | GLI proteins bind promoters of Hh responsive genes to promote transcription REACT:R-HSA-5635851 |
| | Global Genome Nucleotide Excision Repair (GG-NER) REACT:R-HSA-5696399 |
| | Glucagon-like Peptide-1 (GLP1) regulates insulin secretion REACT:R-HSA-381676 |
| | Glucagon signaling in metabolic regulation REACT:R-HSA-163359 |
| | Glucagon signaling pathway KEGG:hsa04922 |
| | Glucagon-type ligand receptors REACT:R-HSA-420092 |
| | Glucocorticoid biosynthesis REACT:R-HSA-194002 |
| | Gluconeogenesis REACT:R-HSA-70263 |
| | Gluconeogenesis, oxaloacetate => fructose-6P KEGG:hsa_M00003 |
| | Glucose metabolism REACT:R-HSA-70326 |
| | Glucose transport REACT:R-HSA-70153 |
| | Glucuronate pathway (uronate pathway) KEGG:hsa_M00014 |
| | Glucuronidation REACT:R-HSA-156588 |
| | Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity REACT:R-HSA-399721 |
| | Glutamate Neurotransmitter Release Cycle REACT:R-HSA-210500 |
| | Glutamatergic synapse KEGG:hsa04724 |
| | Glutathione biosynthesis, glutamate => glutathione KEGG:hsa_M00118 |
| | Glutathione conjugation REACT:R-HSA-156590 |
| | Glutathione metabolism KEGG:hsa00480 |
| | Glutathione synthesis and recycling REACT:R-HSA-174403 |
| | Glycerolipid metabolism KEGG:hsa00561 |
| | Glycerophospholipid biosynthesis REACT:R-HSA-1483206 |
| | Glycerophospholipid catabolism REACT:R-HSA-6814848 |
| | Glycerophospholipid metabolism KEGG:hsa00564 |
| | Glycine degradation REACT:R-HSA-6783984 |
| | Glycine, serine and threonine metabolism KEGG:hsa00260 |
| | Glycogen breakdown (glycogenolysis) REACT:R-HSA-70221 |
| | Glycogen storage diseases REACT:R-HSA-3229121 |
| | Glycogen storage disease type 0 (liver GYS2) REACT:R-HSA-3858516 |
| | Glycogen storage disease type 0 (muscle GYS1) REACT:R-HSA-3828062 |
| | Glycogen storage disease type Ia (G6PC) REACT:R-HSA-3274531 |
| | Glycogen storage disease type Ib (SLC37A4) REACT:R-HSA-3229133 |
| | Glycogen storage disease type II (GAA) REACT:R-HSA-5357609 |
| | Glycogen storage disease type IV (GBE1) REACT:R-HSA-3878781 |
| | Glycogen storage disease type XV (GYG1) REACT:R-HSA-3814836 |
| | Glycogen synthesis REACT:R-HSA-3322077 |
| | Glycolysis REACT:R-HSA-70171 |
| | Glycolysis, core module involving three-carbon compounds KEGG:hsa_M00002 |
| | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate KEGG:hsa_M00001 |
| | Glycolysis / Gluconeogenesis KEGG:hsa00010 |
| | Glycoprotein hormones REACT:R-HSA-209822 |
| | Glycosaminoglycan biosynthesis, chondroitin sulfate backbone KEGG:hsa_M00058 |
| | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate KEGG:hsa00532 |
| | Glycosaminoglycan biosynthesis, heparan sulfate backbone KEGG:hsa_M00059 |
| | Glycosaminoglycan biosynthesis - heparan sulfate / heparin KEGG:hsa00534 |
| | Glycosaminoglycan biosynthesis - keratan sulfate KEGG:hsa00533 |
| | Glycosaminoglycan biosynthesis, linkage tetrasaccharide KEGG:hsa_M00057 |
| | Glycosaminoglycan degradation KEGG:hsa00531 |
| | Glycosaminoglycan metabolism REACT:R-HSA-1630316 |
| | Glycosphingolipid biosynthesis - ganglio series KEGG:hsa00604 |
| | Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 KEGG:hsa_M00069 |
| | Glycosphingolipid biosynthesis - globo and isoglobo series KEGG:hsa00603 |
| | Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer KEGG:hsa_M00068 |
| | Glycosphingolipid biosynthesis - lacto and neolacto series KEGG:hsa00601 |
| | Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer KEGG:hsa_M00070 |
| | Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer KEGG:hsa_M00071 |
| | Glycosphingolipid metabolism REACT:R-HSA-1660662 |
| | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis KEGG:hsa00563 |
| | Glyoxylate and dicarboxylate metabolism KEGG:hsa00630 |
| | Glyoxylate metabolism and glycine degradation REACT:R-HSA-389661 |
| | GnRH signaling pathway KEGG:hsa04912 |
| | Golgi Associated Vesicle Biogenesis REACT:R-HSA-432722 |
| | Golgi Cisternae Pericentriolar Stack Reorganization REACT:R-HSA-162658 |
| | Golgi-to-ER retrograde transport REACT:R-HSA-8856688 |
| | GP1b-IX-V activation signalling REACT:R-HSA-430116 |
| | GPCR downstream signaling REACT:R-HSA-388396 |
| | GPCR ligand binding REACT:R-HSA-500792 |
| | GPI-anchor biosynthesis, core oligosaccharide KEGG:hsa_M00065 |
| | G-protein activation REACT:R-HSA-202040 |
| | G-protein beta:gamma signalling REACT:R-HSA-397795 |
| | G protein gated Potassium channels REACT:R-HSA-1296059 |
| | G-protein mediated events REACT:R-HSA-112040 |
| | GPVI-mediated activation cascade REACT:R-HSA-114604 |
| | Graft-versus-host disease KEGG:hsa05332 |
| | GRB2 events in EGFR signaling REACT:R-HSA-179812 |
| | GRB2 events in ERBB2 signaling REACT:R-HSA-1963640 |
| | GRB2:SOS provides linkage to MAPK signaling for Integrins REACT:R-HSA-354194 |
| | GRB7 events in ERBB2 signaling REACT:R-HSA-1306955 |
| | Growth hormone receptor signaling REACT:R-HSA-982772 |
| | GTP hydrolysis and joining of the 60S ribosomal subunit REACT:R-HSA-72706 |
| | Guanine ribonucleotide biosynthesis IMP => GDP,GTP KEGG:hsa_M00050 |
| | H/ACA ribonucleoprotein complex KEGG:hsa_M00425 |
| | HATs acetylate histones REACT:R-HSA-3214847 |
| | HCN channels REACT:R-HSA-1296061 |
| | HDACs deacetylate histones REACT:R-HSA-3214815 |
| | HDL-mediated lipid transport REACT:R-HSA-194223 |
| | HDMs demethylate histones REACT:R-HSA-3214842 |
| | HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) REACT:R-HSA-5693567 |
| | HDR through Homologous Recombination (HRR) REACT:R-HSA-5685942 |
| | HDR through MMEJ (alt-NHEJ) REACT:R-HSA-5685939 |
| | HDR through Single Strand Annealing (SSA) REACT:R-HSA-5685938 |
| | Hedgehog ligand biogenesis REACT:R-HSA-5358346 |
| | Hedgehog 'off' state REACT:R-HSA-5610787 |
| | Hedgehog 'on' state REACT:R-HSA-5632684 |
| | Hedgehog signaling KEGG:hsa_M00678 |
| | Hedgehog signaling pathway KEGG:hsa04340 |
| | Hematopoietic cell lineage KEGG:hsa04640 |
| | Heme biosynthesis REACT:R-HSA-189451 |
| | Heme degradation REACT:R-HSA-189483 |
| | Hemostasis REACT:R-HSA-109582 |
| | Heparan sulfate degradation KEGG:hsa_M00078 |
| | Heparan sulfate/heparin (HS-GAG) metabolism REACT:R-HSA-1638091 |
| | Hepatitis B KEGG:hsa05161 |
| | Hepatitis C KEGG:hsa05160 |
| | Hereditary fructose intolerance REACT:R-HSA-5657560 |
| | Herpes simplex infection KEGG:hsa05168 |
| | Hexose transport REACT:R-HSA-189200 |
| | HHAT G278V abrogates palmitoylation of Hh-Np REACT:R-HSA-5658034 |
| | Hh mutants abrogate ligand secretion REACT:R-HSA-5387390 |
| | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD REACT:R-HSA-5362768 |
| | HIF-1 signaling pathway KEGG:hsa04066 |
| | Highly calcium permeable nicotinic acetylcholine receptors REACT:R-HSA-629597 |
| | Highly calcium permeable postsynaptic nicotinic acetylcholine receptors REACT:R-HSA-629594 |
| | Highly sodium permeable acetylcholine nicotinic receptors REACT:R-HSA-629587 |
| | Hippo signaling KEGG:hsa_M00683 |
| | Hippo signaling pathway KEGG:hsa04390 |
| | Hippo signaling pathway -multiple species KEGG:hsa04392 |
| | Histamine receptors REACT:R-HSA-390650 |
| | Histidine catabolism REACT:R-HSA-70921 |
| | Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism REACT:R-HSA-6788656 |
| | Histidine metabolism KEGG:hsa00340 |
| | HIV elongation arrest and recovery REACT:R-HSA-167287 |
| | HIV Infection REACT:R-HSA-162906 |
| | HIV Life Cycle REACT:R-HSA-162587 |
| | HIV Transcription Elongation REACT:R-HSA-167169 |
| | HIV Transcription Initiation REACT:R-HSA-167161 |
| | Holo-TFIIH complex KEGG:hsa_M00290 |
| | Homologous DNA Pairing and Strand Exchange REACT:R-HSA-5693579 |
| | Homologous recombination KEGG:hsa03440 |
| | Homology Directed Repair REACT:R-HSA-5693538 |
| | Hormone ligand-binding receptors REACT:R-HSA-375281 |
| | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis REACT:R-HSA-163560 |
| | Host Interactions of HIV factors REACT:R-HSA-162909 |
| | Host Interactions with Influenza Factors REACT:R-HSA-168253 |
| | HRD1/SEL1 ERAD complex KEGG:hsa_M00403 |
| | HSF1 activation REACT:R-HSA-3371511 |
| | HSF1-dependent transactivation REACT:R-HSA-3371571 |
| | HS-GAG biosynthesis REACT:R-HSA-2022928 |
| | HS-GAG degradation REACT:R-HSA-2024096 |
| | HTLV-I infection KEGG:hsa05166 |
| | Huntington's disease KEGG:hsa05016 |
| | HuR (ELAVL1) binds and stabilizes mRNA REACT:R-HSA-450520 |
| | Hyaluronan biosynthesis and export REACT:R-HSA-2142850 |
| | Hyaluronan metabolism REACT:R-HSA-2142845 |
| | Hyaluronan uptake and degradation REACT:R-HSA-2160916 |
| | Hydrolysis of LPC REACT:R-HSA-1483115 |
| | Hydrolysis of LPE REACT:R-HSA-1483152 |
| | Hydroxycarboxylic acid-binding receptors REACT:R-HSA-3296197 |
| | Hypertrophic cardiomyopathy (HCM) KEGG:hsa05410 |
| | Hypusine synthesis from eIF5A-lysine REACT:R-HSA-204626 |
| | IGF1R signaling cascade REACT:R-HSA-2428924 |
| | IkBA variant leads to EDA-ID REACT:R-HSA-5603029 |
| | IKBKB deficiency causes SCID REACT:R-HSA-5602636 |
| | IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) REACT:R-HSA-5603027 |
| | IKK complex recruitment mediated by RIP1 REACT:R-HSA-937041 |
| | IL-17 signaling pathway KEGG:hsa04657 |
| | IL-6-type cytokine receptor ligand interactions REACT:R-HSA-6788467 |
| | Immune System REACT:R-HSA-168256 |
| | Immunoproteasome KEGG:hsa_M00337 |
| | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell REACT:R-HSA-198933 |
| | Import of palmitoyl-CoA into the mitochondrial matrix REACT:R-HSA-200425 |
| | Inactivation of APC/C via direct inhibition of the APC/C complex REACT:R-HSA-141430 |
| | Inactivation of Cdc42 and Rac REACT:R-HSA-428543 |
| | Inactivation, recovery and regulation of the phototransduction cascade REACT:R-HSA-2514859 |
| | Incretin synthesis, secretion, and inactivation REACT:R-HSA-400508 |
| | Infectious disease REACT:R-HSA-5663205 |
| | Inflammasomes REACT:R-HSA-622312 |
| | Inflammatory bowel disease (IBD) KEGG:hsa05321 |
| | Inflammatory mediator regulation of TRP channels KEGG:hsa04750 |
| | Influenza A KEGG:hsa05164 |
| | Influenza Infection REACT:R-HSA-168254 |
| | Influenza Life Cycle REACT:R-HSA-168255 |
| | Influenza Viral RNA Transcription and Replication REACT:R-HSA-168273 |
| | Influenza Virus Induced Apoptosis REACT:R-HSA-168277 |
| | Inhibition of adenylate cyclase pathway REACT:R-HSA-997269 |
| | Inhibition of Host mRNA Processing and RNA Silencing REACT:R-HSA-168315 |
| | Inhibition of IFN-beta REACT:R-HSA-168888 |
| | Inhibition of Interferon Synthesis REACT:R-HSA-168305 |
| | Inhibition of PKR REACT:R-HSA-169131 |
| | Inhibition of replication initiation of damaged DNA by RB1/E2F1 REACT:R-HSA-113501 |
| | Inhibition of Signaling by Overexpressed EGFR REACT:R-HSA-5638303 |
| | Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components REACT:R-HSA-141405 |
| | Inhibition of TSC complex formation by PKB REACT:R-HSA-165181 |
| | Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits REACT:R-HSA-997272 |
| | Initial triggering of complement REACT:R-HSA-166663 |
| | Initiation of Nuclear Envelope Reformation REACT:R-HSA-2995383 |
| | InlA-mediated entry of Listeria monocytogenes into host cells REACT:R-HSA-8876493 |
| | InlB-mediated entry of Listeria monocytogenes into host cell REACT:R-HSA-8875360 |
| | Innate Immune System REACT:R-HSA-168249 |
| | Inosine monophosphate biosynthesis, PRPP + glutamine => IMP KEGG:hsa_M00048 |
| | Inositol phosphate metabolism KEGG:hsa00562 |
| | Inositol phosphate metabolism REACT:R-HSA-1483249 |
| | Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol KEGG:hsa_M00131 |
| | Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate KEGG:hsa_M00132 |
| | Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 KEGG:hsa_M00130 |
| | Inositol transporters REACT:R-HSA-429593 |
| | Insulin effects increased synthesis of Xylulose-5-Phosphate REACT:R-HSA-163754 |
| | Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA REACT:R-HSA-428359 |
| | Insulin processing REACT:R-HSA-264876 |
| | Insulin receptor recycling REACT:R-HSA-77387 |
| | Insulin receptor signalling cascade REACT:R-HSA-74751 |
| | Insulin resistance KEGG:hsa04931 |
| | Insulin secretion KEGG:hsa04911 |
| | Insulin signaling pathway KEGG:hsa04910 |
| | Integration of energy metabolism REACT:R-HSA-163685 |
| | Integration of provirus REACT:R-HSA-162592 |
| | Integration of viral DNA into host genomic DNA REACT:R-HSA-175567 |
| | Integrin alphaIIb beta3 signaling REACT:R-HSA-354192 |
| | Integrin cell surface interactions REACT:R-HSA-216083 |
| | Interaction between L1 and Ankyrins REACT:R-HSA-445095 |
| | Interaction between PHLDA1 and AURKA REACT:R-HSA-8854521 |
| | Interactions of neurexins and neuroligins at synapses REACT:R-HSA-6794361 |
| | Interactions of Rev with host cellular proteins REACT:R-HSA-177243 |
| | Interactions of Tat with host cellular proteins REACT:R-HSA-176034 |
| | Interactions of Vpr with host cellular proteins REACT:R-HSA-176033 |
| | Interaction With Cumulus Cells REACT:R-HSA-2534343 |
| | Interaction With The Zona Pellucida REACT:R-HSA-1300644 |
| | Interconversion of 2-oxoglutarate and 2-hydroxyglutarate REACT:R-HSA-880009 |
| | Interconversion of polyamines REACT:R-HSA-351200 |
| | Interferon alpha/beta signaling REACT:R-HSA-909733 |
| | Interferon gamma signaling REACT:R-HSA-877300 |
| | Interferon Signaling REACT:R-HSA-913531 |
| | Interleukin-10 signaling REACT:R-HSA-6783783 |
| | Interleukin-12 signaling REACT:R-HSA-447115 |
| | Interleukin-17 signaling REACT:R-HSA-448424 |
| | Interleukin-19, 20, 22, 24 REACT:R-HSA-8854691 |
| | Interleukin-1 processing REACT:R-HSA-448706 |
| | Interleukin-1 signaling REACT:R-HSA-446652 |
| | Interleukin-2 signaling REACT:R-HSA-451927 |
| | Interleukin-3, 5 and GM-CSF signaling REACT:R-HSA-512988 |
| | Interleukin-4 and 13 signaling REACT:R-HSA-6785807 |
| | Interleukin-6 family signaling REACT:R-HSA-6783589 |
| | Interleukin-6 signaling REACT:R-HSA-1059683 |
| | Interleukin-7 signaling REACT:R-HSA-1266695 |
| | Interleukin receptor SHC signaling REACT:R-HSA-912526 |
| | Intestinal immune network for IgA production KEGG:hsa04672 |
| | Intestinal infectious diseases REACT:R-HSA-8942233 |
| | Intestinal saccharidase deficiencies REACT:R-HSA-5659898 |
| | Intraflagellar transport REACT:R-HSA-5620924 |
| | Intra-Golgi and retrograde Golgi-to-ER traffic REACT:R-HSA-6811442 |
| | Intra-Golgi traffic REACT:R-HSA-6811438 |
| | Intrinsic Pathway for Apoptosis REACT:R-HSA-109606 |
| | Intrinsic Pathway of Fibrin Clot Formation REACT:R-HSA-140837 |
| | Inwardly rectifying K+ channels REACT:R-HSA-1296065 |
| | Ion channel transport REACT:R-HSA-983712 |
| | Ion homeostasis REACT:R-HSA-5578775 |
| | Ion influx/efflux at host-pathogen interface REACT:R-HSA-6803544 |
| | Ionotropic activity of Kainate Receptors REACT:R-HSA-451306 |
| | Ion transport by P-type ATPases REACT:R-HSA-936837 |
| | IP3 and IP4 transport between cytosol and nucleus REACT:R-HSA-1855196 |
| | IP6 and IP7 transport between cytosol and nucleus REACT:R-HSA-1855229 |
| | IPs transport between cytosol and ER lumen REACT:R-HSA-1855184 |
| | IPs transport between ER lumen and cytosol REACT:R-HSA-1855215 |
| | IPs transport between ER lumen and nucleus REACT:R-HSA-1855156 |
| | IPs transport between nucleus and cytosol REACT:R-HSA-1855170 |
| | IPs transport between nucleus and ER lumen REACT:R-HSA-1855192 |
| | IRAK1 recruits IKK complex REACT:R-HSA-937039 |
| | IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation REACT:R-HSA-975144 |
| | IRAK2 mediated activation of TAK1 complex REACT:R-HSA-937042 |
| | IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation REACT:R-HSA-975163 |
| | IRAK4 deficiency (TLR2/4) REACT:R-HSA-5603041 |
| | IRAK4 deficiency (TLR5) REACT:R-HSA-5603037 |
| | IRE1alpha activates chaperones REACT:R-HSA-381070 |
| | IRF3 mediated activation of type 1 IFN REACT:R-HSA-1606341 |
| | IRF3-mediated induction of type I IFN REACT:R-HSA-3270619 |
| | Iron uptake and transport REACT:R-HSA-917937 |
| | IRS activation REACT:R-HSA-74713 |
| | IRS-mediated signalling REACT:R-HSA-112399 |
| | IRS-related events triggered by IGF1R REACT:R-HSA-2428928 |
| | ISG15 antiviral mechanism REACT:R-HSA-1169408 |
| | JAK-STAT signaling KEGG:hsa_M00684 |
| | Jak-STAT signaling pathway KEGG:hsa04630 |
| | JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 REACT:R-HSA-450321 |
| | Josephin domain DUBs REACT:R-HSA-5689877 |
| | Keratan sulfate biosynthesis REACT:R-HSA-2022854 |
| | Keratan sulfate degradation KEGG:hsa_M00079 |
| | Keratan sulfate degradation REACT:R-HSA-2022857 |
| | Keratan sulfate/keratin metabolism REACT:R-HSA-1638074 |
| | Keratinization REACT:R-HSA-6805567 |
| | Ketone body metabolism REACT:R-HSA-74182 |
| | Kinesins REACT:R-HSA-983189 |
| | KSRP (KHSRP) binds and destabilizes mRNA REACT:R-HSA-450604 |
| | L13a-mediated translational silencing of Ceruloplasmin expression REACT:R-HSA-156827 |
| | L1CAM interactions REACT:R-HSA-373760 |
| | Lactose synthesis REACT:R-HSA-5653890 |
| | Lactosylceramide biosynthesis KEGG:hsa_M00066 |
| | Lagging Strand Synthesis REACT:R-HSA-69186 |
| | Laminin interactions REACT:R-HSA-3000157 |
| | Latent infection of Homo sapiens with Mycobacterium tuberculosis REACT:R-HSA-1222352 |
| | Late Phase of HIV Life Cycle REACT:R-HSA-162599 |
| | LDL-mediated lipid transport REACT:R-HSA-171052 |
| | Leading Strand Synthesis REACT:R-HSA-69109 |
| | Lectin pathway of complement activation REACT:R-HSA-166662 |
| | Legionellosis KEGG:hsa05134 |
| | Leishmaniasis KEGG:hsa05140 |
| | Leucine degradation, leucine => acetoacetate + acetyl-CoA KEGG:hsa_M00036 |
| | Leukocyte transendothelial migration KEGG:hsa04670 |
| | Leukotriene receptors REACT:R-HSA-391906 |
| | LGI-ADAM interactions REACT:R-HSA-5682910 |
| | Ligand-dependent caspase activation REACT:R-HSA-140534 |
| | Ligand-gated ion channel transport REACT:R-HSA-975298 |
| | Ligand-independent caspase activation via DCC REACT:R-HSA-418889 |
| | Ligand-receptor interactions REACT:R-HSA-5632681 |
| | Linoleic acid (LA) metabolism REACT:R-HSA-2046105 |
| | Linoleic acid metabolism KEGG:hsa00591 |
| | Lipid digestion, mobilization, and transport REACT:R-HSA-73923 |
| | Lipoic acid metabolism KEGG:hsa00785 |
| | Lipoprotein metabolism REACT:R-HSA-174824 |
| | Listeria monocytogenes entry into host cells REACT:R-HSA-8876384 |
| | Localization of the PINCH-ILK-PARVIN complex to focal adhesions REACT:R-HSA-446343 |
| | Longevity regulating pathway KEGG:hsa04211 |
| | Longevity regulating pathway - multiple species KEGG:hsa04213 |
| | Long-term depression KEGG:hsa04730 |
| | Long-term potentiation KEGG:hsa04720 |
| | Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling REACT:R-HSA-2644607 |
| | Loss of Function of SMAD2/3 in Cancer REACT:R-HSA-3304349 |
| | Loss of Function of SMAD4 in Cancer REACT:R-HSA-3304347 |
| | Loss of Function of TGFBR1 in Cancer REACT:R-HSA-3656534 |
| | Loss of Function of TGFBR2 in Cancer REACT:R-HSA-3642278 |
| | Loss of Nlp from mitotic centrosomes REACT:R-HSA-380259 |
| | Loss of proteins required for interphase microtubule organization from the centrosome REACT:R-HSA-380284 |
| | LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production REACT:R-HSA-3134973 |
| | Lsm 1-7 complex KEGG:hsa_M00397 |
| | Lsm 2-8 complex KEGG:hsa_M00396 |
| | Lysine biosynthesis KEGG:hsa00300 |
| | Lysine catabolism REACT:R-HSA-71064 |
| | Lysine degradation KEGG:hsa00310 |
| | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA KEGG:hsa_M00032 |
| | Lysosomal glycogen catabolism REACT:R-HSA-5357572 |
| | Lysosomal oligosaccharide catabolism REACT:R-HSA-8853383 |
| | Lysosome KEGG:hsa04142 |
| | Lysosome Vesicle Biogenesis REACT:R-HSA-432720 |
| | Lysosphingolipid and LPA receptors REACT:R-HSA-419408 |
| | Macroautophagy REACT:R-HSA-1632852 |
| | Major pathway of rRNA processing in the nucleolus and cytosol REACT:R-HSA-6791226 |
| | Malaria KEGG:hsa05144 |
| | Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA KEGG:hsa_M00013 |
| | Mannose type O-glycan biosynthesis KEGG:hsa00515 |
| | MAP2K and MAPK activation REACT:R-HSA-5674135 |
| | MAP3K8 (TPL2)-dependent MAPK1/3 activation REACT:R-HSA-5684264 |
| | MAPK1 (ERK2) activation REACT:R-HSA-112411 |
| | MAPK1/MAPK3 signaling REACT:R-HSA-5684996 |
| | MAPK3 (ERK1) activation REACT:R-HSA-110056 |
| | MAPK6/MAPK4 signaling REACT:R-HSA-5687128 |
| | MAPK (ERK1/2) signaling KEGG:hsa_M00687 |
| | MAPK (ERK5) signaling KEGG:hsa_M00690 |
| | MAPK family signaling cascades REACT:R-HSA-5683057 |
| | MAP kinase activation in TLR cascade REACT:R-HSA-450294 |
| | MAPK (JNK) signaling KEGG:hsa_M00688 |
| | MAPK (p38) signaling KEGG:hsa_M00689 |
| | MAPK signaling pathway KEGG:hsa04010 |
| | MAPK targets/ Nuclear events mediated by MAP kinases REACT:R-HSA-450282 |
| | MASTL Facilitates Mitotic Progression REACT:R-HSA-2465910 |
| | Maturity onset diabetes of the young KEGG:hsa04950 |
| | MCM complex KEGG:hsa_M00285 |
| | Measles KEGG:hsa05162 |
| | Meiosis REACT:R-HSA-1500620 |
| | Meiotic recombination REACT:R-HSA-912446 |
| | Meiotic synapsis REACT:R-HSA-1221632 |
| | Melanin biosynthesis REACT:R-HSA-5662702 |
| | Melanogenesis KEGG:hsa04916 |
| | Melanoma KEGG:hsa05218 |
| | Melatonin biosynthesis, tryptophan => serotonin => melatonin KEGG:hsa_M00037 |
| | Membrane binding and targetting of GAG proteins REACT:R-HSA-174490 |
| | Membrane Trafficking REACT:R-HSA-199991 |
| | Metabolic disorders of biological oxidation enzymes REACT:R-HSA-5579029 |
| | Metabolic pathways KEGG:hsa01100 |
| | Metabolism REACT:R-HSA-1430728 |
| | Metabolism of amino acids and derivatives REACT:R-HSA-71291 |
| | Metabolism of Angiotensinogen to Angiotensins REACT:R-HSA-2022377 |
| | Metabolism of carbohydrates REACT:R-HSA-71387 |
| | Metabolism of fat-soluble vitamins REACT:R-HSA-6806667 |
| | Metabolism of folate and pterines REACT:R-HSA-196757 |
| | Metabolism of ingested H2SeO4 and H2SeO3 into H2Se REACT:R-HSA-2408550 |
| | Metabolism of ingested MeSeO2H into MeSeH REACT:R-HSA-5263617 |
| | Metabolism of ingested SeMet, Sec, MeSec into H2Se REACT:R-HSA-2408508 |
| | Metabolism of lipids and lipoproteins REACT:R-HSA-556833 |
| | Metabolism of nitric oxide REACT:R-HSA-202131 |
| | Metabolism of non-coding RNA REACT:R-HSA-194441 |
| | Metabolism of nucleotides REACT:R-HSA-15869 |
| | Metabolism of polyamines REACT:R-HSA-351202 |
| | Metabolism of porphyrins REACT:R-HSA-189445 |
| | Metabolism of proteins REACT:R-HSA-392499 |
| | Metabolism of serotonin REACT:R-HSA-380612 |
| | Metabolism of steroid hormones REACT:R-HSA-196071 |
| | Metabolism of vitamin K REACT:R-HSA-6806664 |
| | Metabolism of vitamins and cofactors REACT:R-HSA-196854 |
| | Metabolism of water-soluble vitamins and cofactors REACT:R-HSA-196849 |
| | Metabolism of xenobiotics by cytochrome P450 KEGG:hsa00980 |
| | MET activates PI3K/AKT signaling REACT:R-HSA-8851907 |
| | MET activates PTK2 signaling REACT:R-HSA-8874081 |
| | MET activates PTPN11 REACT:R-HSA-8865999 |
| | MET activates RAP1 and RAC1 REACT:R-HSA-8875555 |
| | MET activates RAS signaling REACT:R-HSA-8851805 |
| | MET activates STAT3 REACT:R-HSA-8875791 |
| | Metal ion SLC transporters REACT:R-HSA-425410 |
| | Metalloprotease DUBs REACT:R-HSA-5689901 |
| | Metallothioneins bind metals REACT:R-HSA-5661231 |
| | Metal sequestration by antimicrobial proteins REACT:R-HSA-6799990 |
| | Methionine degradation KEGG:hsa_M00035 |
| | Methionine salvage pathway KEGG:hsa_M00034 |
| | Methionine salvage pathway REACT:R-HSA-1237112 |
| | Methylation REACT:R-HSA-156581 |
| | Methylation of MeSeH for excretion REACT:R-HSA-2408552 |
| | MET interacts with TNS proteins REACT:R-HSA-8875513 |
| | MET promotes cell motility REACT:R-HSA-8875878 |
| | MET Receptor Activation REACT:R-HSA-6806942 |
| | MET receptor recycling REACT:R-HSA-8875656 |
| | M/G1 Transition REACT:R-HSA-68874 |
| | MGMT-mediated DNA damage reversal REACT:R-HSA-5657655 |
| | MHC class II antigen presentation REACT:R-HSA-2132295 |
| | MicroRNA (miRNA) biogenesis REACT:R-HSA-203927 |
| | MicroRNAs in cancer KEGG:hsa05206 |
| | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane REACT:R-HSA-190840 |
| | Mineral absorption KEGG:hsa04978 |
| | Mineralocorticoid biosynthesis REACT:R-HSA-193993 |
| | Minus-strand DNA synthesis REACT:R-HSA-164516 |
| | Miscellaneous digestion events REACT:R-HSA-8935690 |
| | Miscellaneous substrates REACT:R-HSA-211958 |
| | Miscellaneous transport and binding events REACT:R-HSA-5223345 |
| | Mismatch repair KEGG:hsa03430 |
| | Mismatch Repair REACT:R-HSA-5358508 |
| | Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) REACT:R-HSA-5358606 |
| | Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) REACT:R-HSA-5358565 |
| | Misspliced GSK3beta mutants stabilize beta-catenin REACT:R-HSA-5339716 |
| | Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling REACT:R-HSA-5339717 |
| | Mitochondrial ABC transporters REACT:R-HSA-1369007 |
| | Mitochondrial biogenesis REACT:R-HSA-1592230 |
| | Mitochondrial Fatty Acid Beta-Oxidation REACT:R-HSA-77289 |
| | mitochondrial fatty acid beta-oxidation of saturated fatty acids REACT:R-HSA-77286 |
| | mitochondrial fatty acid beta-oxidation of unsaturated fatty acids REACT:R-HSA-77288 |
| | Mitochondrial iron-sulfur cluster biogenesis REACT:R-HSA-1362409 |
| | Mitochondrial protein import REACT:R-HSA-1268020 |
| | Mitochondrial transcription initiation REACT:R-HSA-163282 |
| | Mitochondrial transcription termination REACT:R-HSA-163316 |
| | Mitochondrial translation REACT:R-HSA-5368287 |
| | Mitochondrial translation elongation REACT:R-HSA-5389840 |
| | Mitochondrial translation initiation REACT:R-HSA-5368286 |
| | Mitochondrial translation termination REACT:R-HSA-5419276 |
| | Mitochondrial tRNA aminoacylation REACT:R-HSA-379726 |
| | Mitochondrial Uncoupling Proteins REACT:R-HSA-166187 |
| | Mitophagy REACT:R-HSA-5205647 |
| | Mitophagy - animal KEGG:hsa04137 |
| | Mitotic Anaphase REACT:R-HSA-68882 |
| | Mitotic G1-G1/S phases REACT:R-HSA-453279 |
| | Mitotic G2-G2/M phases REACT:R-HSA-453274 |
| | Mitotic Metaphase/Anaphase Transition REACT:R-HSA-68881 |
| | Mitotic Metaphase and Anaphase REACT:R-HSA-2555396 |
| | Mitotic Prometaphase REACT:R-HSA-68877 |
| | Mitotic Prophase REACT:R-HSA-68875 |
| | Mitotic Spindle Checkpoint REACT:R-HSA-69618 |
| | Mitotic Telophase/Cytokinesis REACT:R-HSA-68884 |
| | Molecules associated with elastic fibres REACT:R-HSA-2129379 |
| | Molybdenum cofactor biosynthesis REACT:R-HSA-947581 |
| | Morphine addiction KEGG:hsa05032 |
| | M Phase REACT:R-HSA-68886 |
| | MPS I - Hurler syndrome REACT:R-HSA-2206302 |
| | MPS II - Hunter syndrome REACT:R-HSA-2206296 |
| | MPS IIIA - Sanfilippo syndrome A REACT:R-HSA-2206307 |
| | MPS IIIB - Sanfilippo syndrome B REACT:R-HSA-2206282 |
| | MPS IIIC - Sanfilippo syndrome C REACT:R-HSA-2206291 |
| | MPS IIID - Sanfilippo syndrome D REACT:R-HSA-2206305 |
| | MPS IV - Morquio syndrome A REACT:R-HSA-2206290 |
| | MPS IV - Morquio syndrome B REACT:R-HSA-2206308 |
| | MPS IX - Natowicz syndrome REACT:R-HSA-2206280 |
| | MPS VII - Sly syndrome REACT:R-HSA-2206292 |
| | MPS VI - Maroteaux-Lamy syndrome REACT:R-HSA-2206285 |
| | mRNA 3'-end processing REACT:R-HSA-72187 |
| | mRNA Capping REACT:R-HSA-72086 |
| | mRNA decay by 3' to 5' exoribonuclease REACT:R-HSA-429958 |
| | mRNA decay by 5' to 3' exoribonuclease REACT:R-HSA-430039 |
| | mRNA Editing REACT:R-HSA-75072 |
| | mRNA Editing: A to I Conversion REACT:R-HSA-75064 |
| | mRNA Editing: C to U Conversion REACT:R-HSA-72200 |
| | mRNA Splicing REACT:R-HSA-72172 |
| | mRNA Splicing - Major Pathway REACT:R-HSA-72163 |
| | mRNA Splicing - Minor Pathway REACT:R-HSA-72165 |
| | mRNA surveillance pathway KEGG:hsa03015 |
| | MRN complex KEGG:hsa_M00291 |
| | Mtb iron assimilation by chelation REACT:R-HSA-1222449 |
| | mTORC1-mediated signalling REACT:R-HSA-166208 |
| | mTOR signaling pathway KEGG:hsa04150 |
| | mTOR signalling REACT:R-HSA-165159 |
| | Mucin type O-glycan biosynthesis KEGG:hsa00512 |
| | Mucopolysaccharidoses REACT:R-HSA-2206281 |
| | Multifunctional anion exchangers REACT:R-HSA-427601 |
| | Muscarinic acetylcholine receptors REACT:R-HSA-390648 |
| | Muscle contraction REACT:R-HSA-397014 |
| | MyD88 cascade initiated on plasma membrane REACT:R-HSA-975871 |
| | MyD88 deficiency (TLR2/4) REACT:R-HSA-5602498 |
| | MyD88 deficiency (TLR5) REACT:R-HSA-5602680 |
| | MyD88 dependent cascade initiated on endosome REACT:R-HSA-975155 |
| | MyD88-independent TLR3/TLR4 cascade REACT:R-HSA-166166 |
| | MyD88:Mal cascade initiated on plasma membrane REACT:R-HSA-166058 |
| | Myoclonic epilepsy of Lafora REACT:R-HSA-3785653 |
| | Myogenesis REACT:R-HSA-525793 |
| | Na+/Cl- dependent neurotransmitter transporters REACT:R-HSA-442660 |
| | NADE modulates death signalling REACT:R-HSA-205025 |
| | Na+-dependent glucose transporters REACT:R-HSA-428808 |
| | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex KEGG:hsa_M00146 |
| | NADH dehydrogenase (ubiquinone) 1 beta subcomplex KEGG:hsa_M00147 |
| | NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria KEGG:hsa_M00143 |
| | NADH:ubiquinone oxidoreductase, mitochondria KEGG:hsa_M00142 |
| | NADPH regeneration REACT:R-HSA-389542 |
| | Natural killer cell mediated cytotoxicity KEGG:hsa04650 |
| | NCAM1 interactions REACT:R-HSA-419037 |
| | NCAM signaling for neurite out-growth REACT:R-HSA-375165 |
| | Nectin/Necl trans heterodimerization REACT:R-HSA-420597 |
| | Nef and signal transduction REACT:R-HSA-164944 |
| | Nef Mediated CD4 Down-regulation REACT:R-HSA-167590 |
| | Nef Mediated CD8 Down-regulation REACT:R-HSA-182218 |
| | Nef mediated downregulation of CD28 cell surface expression REACT:R-HSA-164939 |
| | Nef mediated downregulation of MHC class I complex cell surface expression REACT:R-HSA-164940 |
| | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters REACT:R-HSA-164938 |
| | Negative epigenetic regulation of rRNA expression REACT:R-HSA-5250941 |
| | Negative feedback regulation of MAPK pathway REACT:R-HSA-5674499 |
| | Negative regulation of activity of TFAP2 (AP-2) family transcription factors REACT:R-HSA-8866904 |
| | Negative regulation of FGFR1 signaling REACT:R-HSA-5654726 |
| | Negative regulation of FGFR2 signaling REACT:R-HSA-5654727 |
| | Negative regulation of FGFR3 signaling REACT:R-HSA-5654732 |
| | Negative regulation of FGFR4 signaling REACT:R-HSA-5654733 |
| | Negative regulation of MAPK pathway REACT:R-HSA-5675221 |
| | Negative regulation of MET activity REACT:R-HSA-6807004 |
| | Negative regulation of TCF-dependent signaling by DVL-interacting proteins REACT:R-HSA-5368598 |
| | Negative regulation of TCF-dependent signaling by WNT ligand antagonists REACT:R-HSA-3772470 |
| | Negative regulation of the PI3K/AKT network REACT:R-HSA-199418 |
| | Negative regulators of RIG-I/MDA5 signaling REACT:R-HSA-936440 |
| | Neomycin, kanamycin and gentamicin biosynthesis KEGG:hsa00524 |
| | Nephrin interactions REACT:R-HSA-373753 |
| | NEP/NS2 Interacts with the Cellular Export Machinery REACT:R-HSA-168333 |
| | Netrin-1 signaling REACT:R-HSA-373752 |
| | Netrin mediated repulsion signals REACT:R-HSA-418886 |
| | Neuroactive ligand-receptor interaction KEGG:hsa04080 |
| | Neurodegenerative Diseases REACT:R-HSA-8863678 |
| | Neurofascin interactions REACT:R-HSA-447043 |
| | Neuronal System REACT:R-HSA-112316 |
| | Neurophilin interactions with VEGF and VEGFR REACT:R-HSA-194306 |
| | Neurotoxicity of clostridium toxins REACT:R-HSA-168799 |
| | Neurotransmitter Clearance In The Synaptic Cleft REACT:R-HSA-112311 |
| | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell REACT:R-HSA-112314 |
| | Neurotransmitter Release Cycle REACT:R-HSA-112310 |
| | Neurotransmitter uptake and Metabolism In Glial Cells REACT:R-HSA-112313 |
| | Neurotrophin signaling pathway KEGG:hsa04722 |
| | Neutrophil degranulation REACT:R-HSA-6798695 |
| | NFG and proNGF binds to p75NTR REACT:R-HSA-205017 |
| | NF-kappa B signaling pathway KEGG:hsa04064 |
| | NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 REACT:R-HSA-933543 |
| | NF-kB is activated and signals survival REACT:R-HSA-209560 |
| | NGF-independant TRKA activation REACT:R-HSA-187024 |
| | NGF processing REACT:R-HSA-167060 |
| | NGF signalling via TRKA from the plasma membrane REACT:R-HSA-187037 |
| | N-Glycan antennae elongation REACT:R-HSA-975577 |
| | N-glycan antennae elongation in the medial/trans-Golgi REACT:R-HSA-975576 |
| | N-Glycan biosynthesis KEGG:hsa00510 |
| | N-glycan biosynthesis, complex type KEGG:hsa_M00075 |
| | N-glycan precursor biosynthesis KEGG:hsa_M00055 |
| | N-glycan precursor trimming KEGG:hsa_M00073 |
| | N-glycan trimming and elongation in the cis-Golgi REACT:R-HSA-964739 |
| | N-glycan trimming in the ER and Calnexin/Calreticulin cycle REACT:R-HSA-532668 |
| | N-glycosylation by oligosaccharyltransferase KEGG:hsa_M00072 |
| | Nicotinamide salvaging REACT:R-HSA-197264 |
| | Nicotinate and nicotinamide metabolism KEGG:hsa00760 |
| | Nicotinate metabolism REACT:R-HSA-196807 |
| | Nicotine addiction KEGG:hsa05033 |
| | NIK-->noncanonical NF-kB signaling REACT:R-HSA-5676590 |
| | Nitric oxide stimulates guanylate cyclase REACT:R-HSA-392154 |
| | Nitrogen metabolism KEGG:hsa00910 |
| | NOD1/2 Signaling Pathway REACT:R-HSA-168638 |
| | NOD-like receptor signaling pathway KEGG:hsa04621 |
| | Non-alcoholic fatty liver disease (NAFLD) KEGG:hsa04932 |
| | Non-homologous end-joining KEGG:hsa03450 |
| | Nonhomologous End-Joining (NHEJ) REACT:R-HSA-5693571 |
| | Non-integrin membrane-ECM interactions REACT:R-HSA-3000171 |
| | Nonsense-Mediated Decay (NMD) REACT:R-HSA-927802 |
| | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) REACT:R-HSA-975957 |
| | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) REACT:R-HSA-975956 |
| | Non-small cell lung cancer KEGG:hsa05223 |
| | NoRC negatively regulates rRNA expression REACT:R-HSA-427413 |
| | Norepinephrine Neurotransmitter Release Cycle REACT:R-HSA-181430 |
| | NOSIP mediated eNOS trafficking REACT:R-HSA-203754 |
| | NOSTRIN mediated eNOS trafficking REACT:R-HSA-203641 |
| | NOTCH1 Intracellular Domain Regulates Transcription REACT:R-HSA-2122947 |
| | NOTCH2 Activation and Transmission of Signal to the Nucleus REACT:R-HSA-2979096 |
| | NOTCH2 intracellular domain regulates transcription REACT:R-HSA-2197563 |
| | Notch-HLH transcription pathway REACT:R-HSA-350054 |
| | Notch signaling KEGG:hsa_M00682 |
| | Notch signaling pathway KEGG:hsa04330 |
| | NR1D1 (REV-ERBA) represses gene expression REACT:R-HSA-1368071 |
| | NRAGE signals death through JNK REACT:R-HSA-193648 |
| | NrCAM interactions REACT:R-HSA-447038 |
| | NRIF signals cell death from the nucleus REACT:R-HSA-205043 |
| | NS1 Mediated Effects on Host Pathways REACT:R-HSA-168276 |
| | Nuclear Envelope Breakdown REACT:R-HSA-2980766 |
| | Nuclear Envelope Reassembly REACT:R-HSA-2995410 |
| | Nuclear Events (kinase and transcription factor activation) REACT:R-HSA-198725 |
| | Nuclear import of Rev protein REACT:R-HSA-180746 |
| | Nuclear pore complex KEGG:hsa_M00427 |
| | Nuclear Pore Complex (NPC) Disassembly REACT:R-HSA-3301854 |
| | Nuclear Receptor transcription pathway REACT:R-HSA-383280 |
| | Nuclear signaling by ERBB4 REACT:R-HSA-1251985 |
| | Nucleosome assembly REACT:R-HSA-774815 |
| | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways REACT:R-HSA-168643 |
| | Nucleotide excision repair KEGG:hsa03420 |
| | Nucleotide Excision Repair REACT:R-HSA-5696398 |
| | Nucleotide-like (purinergic) receptors REACT:R-HSA-418038 |
| | Nucleotide sugar biosynthesis, eukaryotes KEGG:hsa_M00361 |
| | Nucleotide sugar biosynthesis, galactose => UDP-galactose KEGG:hsa_M00554 |
| | Nucleotide sugar biosynthesis, glucose => UDP-glucose KEGG:hsa_M00549 |
| | O2/CO2 exchange in erythrocytes REACT:R-HSA-1480926 |
| | O-glycan biosynthesis, mucin type core KEGG:hsa_M00056 |
| | O-glycosylation of TSR domain-containing proteins REACT:R-HSA-5173214 |
| | Olfactory Signaling Pathway REACT:R-HSA-381753 |
| | Olfactory transduction KEGG:hsa04740 |
| | Oligomerization of connexins into connexons REACT:R-HSA-190704 |
| | O-linked glycosylation REACT:R-HSA-5173105 |
| | O-linked glycosylation of mucins REACT:R-HSA-913709 |
| | Oncogene Induced Senescence REACT:R-HSA-2559585 |
| | Oncogenic MAPK signaling REACT:R-HSA-6802957 |
| | One carbon pool by folate KEGG:hsa00670 |
| | Oocyte meiosis KEGG:hsa04114 |
| | Opioid Signalling REACT:R-HSA-111885 |
| | Opsins REACT:R-HSA-419771 |
| | Orc1 removal from chromatin REACT:R-HSA-68949 |
| | Orexin and neuropeptides FF and QRFP bind to their respective receptors REACT:R-HSA-389397 |
| | Organelle biogenesis and maintenance REACT:R-HSA-1852241 |
| | Organic anion transport REACT:R-HSA-561048 |
| | Organic anion transporters REACT:R-HSA-428643 |
| | Organic cation/anion/zwitterion transport REACT:R-HSA-549132 |
| | Organic cation transport REACT:R-HSA-549127 |
| | Origin recognition complex KEGG:hsa_M00284 |
| | Osteoclast differentiation KEGG:hsa04380 |
| | Other glycan degradation KEGG:hsa00511 |
| | Other semaphorin interactions REACT:R-HSA-416700 |
| | Other types of O-glycan biosynthesis KEGG:hsa00514 |
| | Ovarian steroidogenesis KEGG:hsa04913 |
| | Ovarian tumor domain proteases REACT:R-HSA-5689896 |
| | Oxidative phosphorylation KEGG:hsa00190 |
| | Oxidative Stress Induced Senescence REACT:R-HSA-2559580 |
| | Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha REACT:R-HSA-1234162 |
| | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha REACT:R-HSA-1234176 |
| | Oxytocin signaling pathway KEGG:hsa04921 |
| | p130Cas linkage to MAPK signaling for integrins REACT:R-HSA-372708 |
| | P2Y receptors REACT:R-HSA-417957 |
| | p38MAPK events REACT:R-HSA-171007 |
| | p53-Dependent G1 DNA Damage Response REACT:R-HSA-69563 |
| | p53-Dependent G1/S DNA damage checkpoint REACT:R-HSA-69580 |
| | p53-Independent DNA Damage Response REACT:R-HSA-69610 |
| | p53-Independent G1/S DNA damage checkpoint REACT:R-HSA-69613 |
| | p53 signaling pathway KEGG:hsa04115 |
| | p75NTR negatively regulates cell cycle via SC1 REACT:R-HSA-193670 |
| | p75 NTR receptor-mediated signalling REACT:R-HSA-193704 |
| | p75NTR recruits signalling complexes REACT:R-HSA-209543 |
| | p75NTR regulates axonogenesis REACT:R-HSA-193697 |
| | p75NTR signals via NF-kB REACT:R-HSA-193639 |
| | p97-Ufd1-Npl4 complex KEGG:hsa_M00400 |
| | Packaging of Eight RNA Segments REACT:R-HSA-168303 |
| | Packaging Of Telomere Ends REACT:R-HSA-171306 |
| | Pancreatic cancer KEGG:hsa05212 |
| | Pancreatic secretion KEGG:hsa04972 |
| | Pantothenate and CoA biosynthesis KEGG:hsa00770 |
| | PAOs oxidise polyamines to amines REACT:R-HSA-141334 |
| | Paradoxical activation of RAF signaling by kinase inactive BRAF REACT:R-HSA-6802955 |
| | Parkinson's disease KEGG:hsa05012 |
| | Passive transport by Aquaporins REACT:R-HSA-432047 |
| | Pathogenic Escherichia coli infection KEGG:hsa05130 |
| | Pathways in cancer KEGG:hsa05200 |
| | Pausing and recovery of HIV elongation REACT:R-HSA-167290 |
| | Pausing and recovery of Tat-mediated HIV elongation REACT:R-HSA-167238 |
| | PCNA-Dependent Long Patch Base Excision Repair REACT:R-HSA-5651801 |
| | PCP/CE pathway REACT:R-HSA-4086400 |
| | PD-1 signaling REACT:R-HSA-389948 |
| | PDE3B signalling REACT:R-HSA-165160 |
| | PECAM1 interactions REACT:R-HSA-210990 |
| | Pentose and glucuronate interconversions KEGG:hsa00040 |
| | Pentose phosphate pathway KEGG:hsa00030 |
| | Pentose phosphate pathway disease REACT:R-HSA-6791465 |
| | Pentose phosphate pathway (hexose monophosphate shunt) REACT:R-HSA-71336 |
| | Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P KEGG:hsa_M00007 |
| | Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P KEGG:hsa_M00006 |
| | Pentose phosphate pathway (Pentose phosphate cycle) KEGG:hsa_M00004 |
| | Peptide chain elongation REACT:R-HSA-156902 |
| | Peptide hormone biosynthesis REACT:R-HSA-209952 |
| | Peptide hormone metabolism REACT:R-HSA-2980736 |
| | Peptide ligand-binding receptors REACT:R-HSA-375276 |
| | PERK regulates gene expression REACT:R-HSA-381042 |
| | Peroxisomal lipid metabolism REACT:R-HSA-390918 |
| | Peroxisome KEGG:hsa04146 |
| | Pertussis KEGG:hsa05133 |
| | Phagosome KEGG:hsa04145 |
| | Phase 0 - rapid depolarisation REACT:R-HSA-5576892 |
| | Phase 1 - Functionalization of compounds REACT:R-HSA-211945 |
| | Phase 1 - inactivation of fast Na+ channels REACT:R-HSA-5576894 |
| | Phase 2 - plateau phase REACT:R-HSA-5576893 |
| | Phase 3 - rapid repolarisation REACT:R-HSA-5576890 |
| | Phase 4 - resting membrane potential REACT:R-HSA-5576886 |
| | Phase II conjugation REACT:R-HSA-156580 |
| | Phenylalanine and tyrosine catabolism REACT:R-HSA-71182 |
| | Phenylalanine metabolism KEGG:hsa00360 |
| | Phenylalanine, tyrosine and tryptophan biosynthesis KEGG:hsa00400 |
| | Phenylketonuria REACT:R-HSA-2160456 |
| | Phosphate bond hydrolysis by NTPDase proteins REACT:R-HSA-8850843 |
| | Phosphate bond hydrolysis by NUDT proteins REACT:R-HSA-2393930 |
| | Phosphatidylcholine (PC) biosynthesis, choline => PC KEGG:hsa_M00090 |
| | Phosphatidylcholine (PC) biosynthesis, PE => PC KEGG:hsa_M00091 |
| | Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE KEGG:hsa_M00092 |
| | Phosphatidylinositol signaling system KEGG:hsa04070 |
| | Phospholipase C-mediated cascade: FGFR1 REACT:R-HSA-5654219 |
| | Phospholipase C-mediated cascade; FGFR2 REACT:R-HSA-5654221 |
| | Phospholipase C-mediated cascade; FGFR3 REACT:R-HSA-5654227 |
| | Phospholipase C-mediated cascade; FGFR4 REACT:R-HSA-5654228 |
| | Phospholipase D signaling pathway KEGG:hsa04072 |
| | Phospholipid metabolism REACT:R-HSA-1483257 |
| | Phosphonate and phosphinate metabolism KEGG:hsa00440 |
| | phospho-PLA2 pathway REACT:R-HSA-111995 |
| | Phosphorylation of CD3 and TCR zeta chains REACT:R-HSA-202427 |
| | Phosphorylation of Emi1 REACT:R-HSA-176417 |
| | Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes REACT:R-HSA-69200 |
| | Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes REACT:R-HSA-170145 |
| | Phosphorylation of the APC/C REACT:R-HSA-176412 |
| | phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex REACT:R-HSA-4839743 |
| | Phototransduction KEGG:hsa04744 |
| | Physiological factors REACT:R-HSA-5578768 |
| | PI3K/AKT activation REACT:R-HSA-198203 |
| | PI3K-Akt signaling KEGG:hsa_M00676 |
| | PI3K/AKT Signaling in Cancer REACT:R-HSA-2219528 |
| | PI3K-Akt signaling pathway KEGG:hsa04151 |
| | PI3K Cascade REACT:R-HSA-109704 |
| | PI-3K cascade:FGFR1 REACT:R-HSA-5654689 |
| | PI-3K cascade:FGFR2 REACT:R-HSA-5654695 |
| | PI-3K cascade:FGFR3 REACT:R-HSA-5654710 |
| | PI-3K cascade:FGFR4 REACT:R-HSA-5654720 |
| | PI3K events in ERBB2 signaling REACT:R-HSA-1963642 |
| | PI3K events in ERBB4 signaling REACT:R-HSA-1250342 |
| | PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling REACT:R-HSA-6811558 |
| | PI5P Regulates TP53 Acetylation REACT:R-HSA-6811555 |
| | PI and PC transport between ER and Golgi membranes REACT:R-HSA-1483196 |
| | PI Metabolism REACT:R-HSA-1483255 |
| | Pink/Parkin Mediated Mitophagy REACT:R-HSA-5205685 |
| | PIP3 activates AKT signaling REACT:R-HSA-1257604 |
| | PIPs transport between early and late endosome membranes REACT:R-HSA-1660502 |
| | PIPs transport between early endosome and Golgi membranes REACT:R-HSA-1660537 |
| | PIPs transport between Golgi and plasma membranes REACT:R-HSA-1660510 |
| | PIPs transport between late endosome and Golgi membranes REACT:R-HSA-1660508 |
| | PIPs transport between plasma and early endosome membranes REACT:R-HSA-1660524 |
| | PIWI-interacting RNA (piRNA) biogenesis REACT:R-HSA-5601884 |
| | PKA activation REACT:R-HSA-163615 |
| | PKA activation in glucagon signalling REACT:R-HSA-164378 |
| | PKA-mediated phosphorylation of CREB REACT:R-HSA-111931 |
| | PKA-mediated phosphorylation of key metabolic factors REACT:R-HSA-163358 |
| | PKB-mediated events REACT:R-HSA-109703 |
| | PKMTs methylate histone lysines REACT:R-HSA-3214841 |
| | Plasmalogen biosynthesis REACT:R-HSA-75896 |
| | Platelet activation KEGG:hsa04611 |
| | Platelet activation, signaling and aggregation REACT:R-HSA-76002 |
| | Platelet Adhesion to exposed collagen REACT:R-HSA-75892 |
| | Platelet Aggregation (Plug Formation) REACT:R-HSA-76009 |
| | Platelet calcium homeostasis REACT:R-HSA-418360 |
| | Platelet degranulation REACT:R-HSA-114608 |
| | Platelet homeostasis REACT:R-HSA-418346 |
| | Platelet sensitization by LDL REACT:R-HSA-432142 |
| | Platinum drug resistance KEGG:hsa01524 |
| | PLC beta mediated events REACT:R-HSA-112043 |
| | PLCG1 events in ERBB2 signaling REACT:R-HSA-1251932 |
| | PLC-gamma1 signalling REACT:R-HSA-167021 |
| | Plus-strand DNA synthesis REACT:R-HSA-164525 |
| | POLB-Dependent Long Patch Base Excision Repair REACT:R-HSA-110362 |
| | Polo-like kinase mediated events REACT:R-HSA-156711 |
| | Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine KEGG:hsa_M00133 |
| | Polyamine biosynthesis, arginine => ornithine => putrescine KEGG:hsa_M00134 |
| | Polymerase switching REACT:R-HSA-69091 |
| | Polymerase switching on the C-strand of the telomere REACT:R-HSA-174411 |
| | Porphyrin and chlorophyll metabolism KEGG:hsa00860 |
| | Positive epigenetic regulation of rRNA expression REACT:R-HSA-5250913 |
| | Post-chaperonin tubulin folding pathway REACT:R-HSA-389977 |
| | Post NMDA receptor activation events REACT:R-HSA-438064 |
| | Postsynaptic nicotinic acetylcholine receptors REACT:R-HSA-622327 |
| | Post-transcriptional silencing by small RNAs REACT:R-HSA-426496 |
| | Post-translational modification: synthesis of GPI-anchored proteins REACT:R-HSA-163125 |
| | Post-translational protein modification REACT:R-HSA-597592 |
| | Potassium Channels REACT:R-HSA-1296071 |
| | Potassium transport channels REACT:R-HSA-1296067 |
| | POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation REACT:R-HSA-2892247 |
| | POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation REACT:R-HSA-2892245 |
| | PP2A-mediated dephosphorylation of key metabolic factors REACT:R-HSA-163767 |
| | PPARA activates gene expression REACT:R-HSA-1989781 |
| | PPAR signaling pathway KEGG:hsa03320 |
| | PRC2 methylates histones and DNA REACT:R-HSA-212300 |
| | Prefoldin mediated transfer of substrate to CCT/TriC REACT:R-HSA-389957 |
| | Pregnenolone biosynthesis REACT:R-HSA-196108 |
| | Pre-NOTCH Expression and Processing REACT:R-HSA-1912422 |
| | Pre-NOTCH Processing in Golgi REACT:R-HSA-1912420 |
| | Pre-NOTCH Processing in the Endoplasmic Reticulum REACT:R-HSA-1912399 |
| | Pre-NOTCH Transcription and Translation REACT:R-HSA-1912408 |
| | Presynaptic function of Kainate receptors REACT:R-HSA-500657 |
| | Presynaptic nicotinic acetylcholine receptors REACT:R-HSA-622323 |
| | Presynaptic phase of homologous DNA pairing and strand exchange REACT:R-HSA-5693616 |
| | Primary bile acid biosynthesis KEGG:hsa00120 |
| | Primary immunodeficiency KEGG:hsa05340 |
| | Prion diseases KEGG:hsa05020 |
| | Processing and activation of SUMO REACT:R-HSA-3215018 |
| | Processing of Capped Intron-Containing Pre-mRNA REACT:R-HSA-72203 |
| | Processing of Capped Intronless Pre-mRNA REACT:R-HSA-75067 |
| | Processing of DNA double-strand break ends REACT:R-HSA-5693607 |
| | Processing of Intronless Pre-mRNAs REACT:R-HSA-77595 |
| | Processive synthesis on the C-strand of the telomere REACT:R-HSA-174414 |
| | Processive synthesis on the lagging strand REACT:R-HSA-69183 |
| | Progesterone-mediated oocyte maturation KEGG:hsa04914 |
| | Programmed Cell Death REACT:R-HSA-5357801 |
| | Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 REACT:R-HSA-964827 |
| | Prolactin receptor signaling REACT:R-HSA-1170546 |
| | Prolactin signaling pathway KEGG:hsa04917 |
| | Proline biosynthesis, glutamate => proline KEGG:hsa_M00015 |
| | Proline catabolism REACT:R-HSA-70688 |
| | Prolonged ERK activation events REACT:R-HSA-169893 |
| | Propanoate metabolism KEGG:hsa00640 |
| | Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA KEGG:hsa_M00741 |
| | Propionyl-CoA catabolism REACT:R-HSA-71032 |
| | Prostacyclin signalling through prostacyclin receptor REACT:R-HSA-392851 |
| | Prostanoid ligand receptors REACT:R-HSA-391908 |
| | Prostate cancer KEGG:hsa05215 |
| | Proteasome KEGG:hsa03050 |
| | Proteasome, 19S regulatory particle (PA700) KEGG:hsa_M00341 |
| | Proteasome, 20S core particle KEGG:hsa_M00340 |
| | Protein digestion and absorption KEGG:hsa04974 |
| | Protein export KEGG:hsa03060 |
| | Protein folding REACT:R-HSA-391251 |
| | Protein methylation REACT:R-HSA-8876725 |
| | Protein processing in endoplasmic reticulum KEGG:hsa04141 |
| | Protein-protein interactions at synapses REACT:R-HSA-6794362 |
| | Protein repair REACT:R-HSA-5676934 |
| | Protein ubiquitination REACT:R-HSA-8852135 |
| | Proteoglycans in cancer KEGG:hsa05205 |
| | Proton-coupled monocarboxylate transport REACT:R-HSA-433692 |
| | Proton-coupled neutral amino acid transporters REACT:R-HSA-428559 |
| | Proton/oligopeptide cotransporters REACT:R-HSA-427975 |
| | Proximal tubule bicarbonate reclamation KEGG:hsa04964 |
| | PRPP biosynthesis, ribose 5P => PRPP KEGG:hsa_M00005 |
| | PTEN Loss of Function in Cancer REACT:R-HSA-5674404 |
| | PTK6 Activates STAT3 REACT:R-HSA-8849474 |
| | PTK6 Down-Regulation REACT:R-HSA-8849472 |
| | PTK6 Expression REACT:R-HSA-8849473 |
| | PTK6 promotes HIF1A stabilization REACT:R-HSA-8857538 |
| | PTK6 Regulates Cell Cycle REACT:R-HSA-8849470 |
| | PTK6 Regulates Proteins Involved in RNA Processing REACT:R-HSA-8849468 |
| | PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases REACT:R-HSA-8849471 |
| | PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 REACT:R-HSA-8849469 |
| | Purine catabolism REACT:R-HSA-74259 |
| | Purine metabolism KEGG:hsa00230 |
| | Purine metabolism REACT:R-HSA-73847 |
| | Purine ribonucleoside monophosphate biosynthesis REACT:R-HSA-73817 |
| | Purine salvage REACT:R-HSA-74217 |
| | Pyrimidine biosynthesis REACT:R-HSA-500753 |
| | Pyrimidine catabolism REACT:R-HSA-73621 |
| | Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate KEGG:hsa_M00046 |
| | Pyrimidine metabolism KEGG:hsa00240 |
| | Pyrimidine metabolism REACT:R-HSA-73848 |
| | Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP KEGG:hsa_M00052 |
| | Pyrimidine salvage reactions REACT:R-HSA-73614 |
| | Pyrophosphate hydrolysis REACT:R-HSA-71737 |
| | Pyruvate metabolism KEGG:hsa00620 |
| | Pyruvate metabolism REACT:R-HSA-70268 |
| | Pyruvate metabolism and Citric Acid (TCA) cycle REACT:R-HSA-71406 |
| | Pyruvate oxidation, pyruvate => acetyl-CoA KEGG:hsa_M00307 |
| | RAB GEFs exchange GTP for GDP on RABs REACT:R-HSA-8876198 |
| | RAB geranylgeranylation REACT:R-HSA-8873719 |
| | RA biosynthesis pathway REACT:R-HSA-5365859 |
| | RAF activation REACT:R-HSA-5673000 |
| | RAF-independent MAPK1/3 activation REACT:R-HSA-112409 |
| | RAF/MAP kinase cascade REACT:R-HSA-5673001 |
| | Rap1 signaling pathway KEGG:hsa04015 |
| | Rap1 signalling REACT:R-HSA-392517 |
| | Ras activation uopn Ca2+ infux through NMDA receptor REACT:R-HSA-442982 |
| | RAS signaling downstream of NF1 loss-of-function variants REACT:R-HSA-6802953 |
| | Ras signaling pathway KEGG:hsa04014 |
| | Reactions specific to the complex N-glycan synthesis pathway REACT:R-HSA-975578 |
| | Reactions specific to the hybrid N-glycan synthesis pathway REACT:R-HSA-975574 |
| | Recognition and association of DNA glycosylase with site containing an affected purine REACT:R-HSA-110330 |
| | Recognition and association of DNA glycosylase with site containing an affected pyrimidine REACT:R-HSA-110328 |
| | Recognition of DNA damage by PCNA-containing replication complex REACT:R-HSA-110314 |
| | Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks REACT:R-HSA-5693565 |
| | Recruitment of mitotic centrosome proteins and complexes REACT:R-HSA-380270 |
| | Recruitment of NuMA to mitotic centrosomes REACT:R-HSA-380320 |
| | Recycling of bile acids and salts REACT:R-HSA-159418 |
| | Recycling of eIF2:GDP REACT:R-HSA-72731 |
| | Recycling pathway of L1 REACT:R-HSA-437239 |
| | Reduction of cytosolic Ca++ levels REACT:R-HSA-418359 |
| | Reelin signalling pathway REACT:R-HSA-8866376 |
| | Regulated Necrosis REACT:R-HSA-5218859 |
| | Regulated proteolysis of p75NTR REACT:R-HSA-193692 |
| | Regulation by c-FLIP REACT:R-HSA-3371378 |
| | Regulation by TREX1 REACT:R-HSA-3248023 |
| | Regulation of actin cytoskeleton KEGG:hsa04810 |
| | Regulation of actin dynamics for phagocytic cup formation REACT:R-HSA-2029482 |
| | Regulation of activated PAK-2p34 by proteasome mediated degradation REACT:R-HSA-211733 |
| | Regulation of APC/C activators between G1/S and early anaphase REACT:R-HSA-176408 |
| | Regulation of Apoptosis REACT:R-HSA-169911 |
| | Regulation of beta-cell development REACT:R-HSA-186712 |
| | Regulation of cholesterol biosynthesis by SREBP (SREBF) REACT:R-HSA-1655829 |
| | Regulation of Commissural axon pathfinding by Slit and Robo REACT:R-HSA-428542 |
| | Regulation of Complement cascade REACT:R-HSA-977606 |
| | Regulation of cytoskeletal remodeling and cell spreading by IPP complex components REACT:R-HSA-446388 |
| | Regulation of DNA replication REACT:R-HSA-69304 |
| | Regulation of FZD by ubiquitination REACT:R-HSA-4641263 |
| | Regulation of gap junction activity REACT:R-HSA-191650 |
| | Regulation of gene expression by Hypoxia-inducible Factor REACT:R-HSA-1234158 |
| | Regulation of gene expression in beta cells REACT:R-HSA-210745 |
| | Regulation of gene expression in early pancreatic precursor cells REACT:R-HSA-210747 |
| | Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells REACT:R-HSA-210746 |
| | Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells REACT:R-HSA-210744 |
| | Regulation of Glucokinase by Glucokinase Regulatory Protein REACT:R-HSA-170822 |
| | Regulation of HSF1-mediated heat shock response REACT:R-HSA-3371453 |
| | Regulation of Hypoxia-inducible Factor (HIF) by oxygen REACT:R-HSA-1234174 |
| | Regulation of IFNA signaling REACT:R-HSA-912694 |
| | Regulation of IFNG signaling REACT:R-HSA-877312 |
| | Regulation of innate immune responses to cytosolic DNA REACT:R-HSA-3134975 |
| | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) REACT:R-HSA-381426 |
| | Regulation of insulin secretion REACT:R-HSA-422356 |
| | Regulation of KIT signaling REACT:R-HSA-1433559 |
| | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) REACT:R-HSA-400206 |
| | Regulation of lipolysis in adipocytes KEGG:hsa04923 |
| | Regulation of mitotic cell cycle REACT:R-HSA-453276 |
| | Regulation of mRNA stability by proteins that bind AU-rich elements REACT:R-HSA-450531 |
| | Regulation of necroptotic cell death REACT:R-HSA-5675482 |
| | Regulation of ornithine decarboxylase (ODC) REACT:R-HSA-350562 |
| | Regulation of PAK-2p34 activity by PS-GAP/RHG10 REACT:R-HSA-211728 |
| | Regulation of PLK1 Activity at G2/M Transition REACT:R-HSA-2565942 |
| | Regulation of pyruvate dehydrogenase (PDH) complex REACT:R-HSA-204174 |
| | Regulation of RAS by GAPs REACT:R-HSA-5658442 |
| | Regulation of signaling by CBL REACT:R-HSA-912631 |
| | Regulation of signaling by NODAL REACT:R-HSA-1433617 |
| | Regulation of thyroid hormone activity REACT:R-HSA-350864 |
| | Regulation of TLR by endogenous ligand REACT:R-HSA-5686938 |
| | Regulation of TNFR1 signaling REACT:R-HSA-5357905 |
| | Regulation of TP53 Activity REACT:R-HSA-5633007 |
| | Regulation of TP53 Activity through Acetylation REACT:R-HSA-6804758 |
| | Regulation of TP53 Activity through Association with Co-factors REACT:R-HSA-6804759 |
| | Regulation of TP53 Activity through Methylation REACT:R-HSA-6804760 |
| | Regulation of TP53 Activity through Phosphorylation REACT:R-HSA-6804756 |
| | Regulation of TP53 Degradation REACT:R-HSA-6804757 |
| | Regulation of TP53 Expression REACT:R-HSA-6804754 |
| | Regulation of TP53 Expression and Degradation REACT:R-HSA-6806003 |
| | Relaxin receptors REACT:R-HSA-444821 |
| | Release REACT:R-HSA-168298 |
| | Release of apoptotic factors from the mitochondria REACT:R-HSA-111457 |
| | Release of Hh-Np from the secreting cell REACT:R-HSA-5362798 |
| | Removal of aminoterminal propeptides from gamma-carboxylated proteins REACT:R-HSA-159782 |
| | Removal of licensing factors from origins REACT:R-HSA-69300 |
| | Removal of the Flap Intermediate REACT:R-HSA-69166 |
| | Removal of the Flap Intermediate from the C-strand REACT:R-HSA-174437 |
| | Renal cell carcinoma KEGG:hsa05211 |
| | Renin-angiotensin system KEGG:hsa04614 |
| | Renin secretion KEGG:hsa04924 |
| | Repression of WNT target genes REACT:R-HSA-4641265 |
| | Reproduction REACT:R-HSA-1474165 |
| | Resolution of Abasic Sites (AP sites) REACT:R-HSA-73933 |
| | Resolution of AP sites via the multiple-nucleotide patch replacement pathway REACT:R-HSA-110373 |
| | Resolution of AP sites via the single-nucleotide replacement pathway REACT:R-HSA-110381 |
| | Resolution of D-Loop Structures REACT:R-HSA-5693537 |
| | Resolution of D-loop Structures through Holliday Junction Intermediates REACT:R-HSA-5693568 |
| | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) REACT:R-HSA-5693554 |
| | Resolution of Sister Chromatid Cohesion REACT:R-HSA-2500257 |
| | Respiratory electron transport REACT:R-HSA-611105 |
| | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. REACT:R-HSA-163200 |
| | Response of Mtb to phagocytosis REACT:R-HSA-1222499 |
| | Response to elevated platelet cytosolic Ca2+ REACT:R-HSA-76005 |
| | Response to metal ions REACT:R-HSA-5660526 |
| | Retinoid cycle disease events REACT:R-HSA-2453864 |
| | Retinoid metabolism and transport REACT:R-HSA-975634 |
| | Retinoid metabolism disease events REACT:R-HSA-6809583 |
| | Retinol metabolism KEGG:hsa00830 |
| | Retrograde endocannabinoid signaling KEGG:hsa04723 |
| | Retrograde neurotrophin signalling REACT:R-HSA-177504 |
| | Retrograde transport at the Trans-Golgi-Network REACT:R-HSA-6811440 |
| | RET signaling REACT:R-HSA-8853659 |
| | Reuptake of GABA REACT:R-HSA-888593 |
| | Reversal of alkylation damage by DNA dioxygenases REACT:R-HSA-73943 |
| | Reverse Transcription of HIV RNA REACT:R-HSA-162589 |
| | Reversible hydration of carbon dioxide REACT:R-HSA-1475029 |
| | Rev-mediated nuclear export of HIV RNA REACT:R-HSA-165054 |
| | RF-C complex KEGG:hsa_M00289 |
| | Rhesus glycoproteins mediate ammonium transport. REACT:R-HSA-444411 |
| | Rheumatoid arthritis KEGG:hsa05323 |
| | Rho GTPase cycle REACT:R-HSA-194840 |
| | RHO GTPase Effectors REACT:R-HSA-195258 |
| | RHO GTPases activate CIT REACT:R-HSA-5625900 |
| | RHO GTPases Activate Formins REACT:R-HSA-5663220 |
| | RHO GTPases activate IQGAPs REACT:R-HSA-5626467 |
| | RHO GTPases activate KTN1 REACT:R-HSA-5625970 |
| | RHO GTPases Activate NADPH Oxidases REACT:R-HSA-5668599 |
| | RHO GTPases activate PAKs REACT:R-HSA-5627123 |
| | RHO GTPases activate PKNs REACT:R-HSA-5625740 |
| | RHO GTPases Activate Rhotekin and Rhophilins REACT:R-HSA-5666185 |
| | RHO GTPases Activate ROCKs REACT:R-HSA-5627117 |
| | RHO GTPases Activate WASPs and WAVEs REACT:R-HSA-5663213 |
| | RHO GTPases regulate CFTR trafficking REACT:R-HSA-5627083 |
| | Riboflavin metabolism KEGG:hsa00740 |
| | Ribosomal scanning and start codon recognition REACT:R-HSA-72702 |
| | Ribosome KEGG:hsa03010 |
| | Ribosome biogenesis in eukaryotes KEGG:hsa03008 |
| | Ribosome, eukaryotes KEGG:hsa_M00177 |
| | RIG-I-like receptor signaling pathway KEGG:hsa04622 |
| | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways REACT:R-HSA-168928 |
| | RIPK1-mediated regulated necrosis REACT:R-HSA-5213460 |
| | RIP-mediated NFkB activation via ZBP1 REACT:R-HSA-1810476 |
| | RMTs methylate histone arginines REACT:R-HSA-3214858 |
| | RNA degradation KEGG:hsa03018 |
| | RNA Pol II CTD phosphorylation and interaction with CE REACT:R-HSA-77075 |
| | RNA Pol II CTD phosphorylation and interaction with CE during HIV infection REACT:R-HSA-167160 |
| | RNA polymerase KEGG:hsa03020 |
| | RNA Polymerase I Chain Elongation REACT:R-HSA-73777 |
| | RNA polymerase I, eukaryotes KEGG:hsa_M00182 |
| | RNA polymerase II, eukaryotes KEGG:hsa_M00180 |
| | RNA Polymerase II HIV Promoter Escape REACT:R-HSA-167162 |
| | RNA Polymerase III Abortive And Retractive Initiation REACT:R-HSA-749476 |
| | RNA Polymerase III Chain Elongation REACT:R-HSA-73780 |
| | RNA polymerase III, eukaryotes KEGG:hsa_M00181 |
| | RNA Polymerase III Transcription REACT:R-HSA-74158 |
| | RNA Polymerase III Transcription Initiation REACT:R-HSA-76046 |
| | RNA Polymerase III Transcription Initiation From Type 1 Promoter REACT:R-HSA-76061 |
| | RNA Polymerase III Transcription Initiation From Type 2 Promoter REACT:R-HSA-76066 |
| | RNA Polymerase III Transcription Initiation From Type 3 Promoter REACT:R-HSA-76071 |
| | RNA Polymerase III Transcription Termination REACT:R-HSA-73980 |
| | RNA Polymerase II Pre-transcription Events REACT:R-HSA-674695 |
| | RNA Polymerase II Promoter Escape REACT:R-HSA-73776 |
| | RNA polymerase II transcribes snRNA genes REACT:R-HSA-6807505 |
| | RNA Polymerase II Transcription REACT:R-HSA-73857 |
| | RNA Polymerase II Transcription Elongation REACT:R-HSA-75955 |
| | RNA Polymerase II Transcription Initiation REACT:R-HSA-75953 |
| | RNA Polymerase II Transcription Initiation And Promoter Clearance REACT:R-HSA-76042 |
| | RNA Polymerase II Transcription Pre-Initiation And Promoter Opening REACT:R-HSA-73779 |
| | RNA Polymerase II Transcription Termination REACT:R-HSA-73856 |
| | RNA Polymerase I Promoter Clearance REACT:R-HSA-73854 |
| | RNA Polymerase I Promoter Escape REACT:R-HSA-73772 |
| | RNA Polymerase I Promoter Opening REACT:R-HSA-73728 |
| | RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription REACT:R-HSA-504046 |
| | RNA Polymerase I Transcription REACT:R-HSA-73864 |
| | RNA Polymerase I Transcription Initiation REACT:R-HSA-73762 |
| | RNA Polymerase I Transcription Termination REACT:R-HSA-73863 |
| | RNA transport KEGG:hsa03013 |
| | RNF mutants show enhanced WNT signaling and proliferation REACT:R-HSA-5340588 |
| | Role of Abl in Robo-Slit signaling REACT:R-HSA-428890 |
| | Role of LAT2/NTAL/LAB on calcium mobilization REACT:R-HSA-2730905 |
| | Role of phospholipids in phagocytosis REACT:R-HSA-2029485 |
| | Role of second messengers in netrin-1 signaling REACT:R-HSA-418890 |
| | RORA activates gene expression REACT:R-HSA-1368082 |
| | ROS, RNS production in phagocytes REACT:R-HSA-1222556 |
| | RPA complex KEGG:hsa_M00288 |
| | RPIA deficiency: failed conversion of R5P to RU5P REACT:R-HSA-5659996 |
| | RPIA deficiency: failed conversion of RU5P to R5P REACT:R-HSA-6791461 |
| | rRNA modification in the mitochondrion REACT:R-HSA-6793080 |
| | rRNA modification in the nucleus and cytosol REACT:R-HSA-6790901 |
| | rRNA processing REACT:R-HSA-72312 |
| | rRNA processing in the mitochondrion REACT:R-HSA-8868766 |
| | rRNA processing in the nucleus and cytosol REACT:R-HSA-8868773 |
| | RSK activation REACT:R-HSA-444257 |
| | S33 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358747 |
| | S37 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358749 |
| | S45 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358751 |
| | Salivary secretion KEGG:hsa04970 |
| | Salmonella infection KEGG:hsa05132 |
| | SALM protein interactions at the synapses REACT:R-HSA-8849932 |
| | Scavenging by Class A Receptors REACT:R-HSA-3000480 |
| | Scavenging by Class B Receptors REACT:R-HSA-3000471 |
| | Scavenging by Class F Receptors REACT:R-HSA-3000484 |
| | Scavenging by Class H Receptors REACT:R-HSA-3000497 |
| | Scavenging of heme from plasma REACT:R-HSA-2168880 |
| | SCF-beta-TrCP mediated degradation of Emi1 REACT:R-HSA-174113 |
| | SCF-BTRC complex KEGG:hsa_M00380 |
| | SCF-FBS complex KEGG:hsa_M00382 |
| | SCF-FBW7 complex KEGG:hsa_M00387 |
| | SCF-SKP2 complex KEGG:hsa_M00381 |
| | SCF(Skp2)-mediated degradation of p27/p21 REACT:R-HSA-187577 |
| | Sec61 complex KEGG:hsa_M00401 |
| | Selenoamino acid metabolism REACT:R-HSA-2408522 |
| | Selenocompound metabolism KEGG:hsa00450 |
| | Selenocysteine synthesis REACT:R-HSA-2408557 |
| | Sema3A PAK dependent Axon repulsion REACT:R-HSA-399954 |
| | SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion REACT:R-HSA-399955 |
| | Sema4D induced cell migration and growth-cone collapse REACT:R-HSA-416572 |
| | Sema4D in semaphorin signaling REACT:R-HSA-400685 |
| | Sema4D mediated inhibition of cell attachment and migration REACT:R-HSA-416550 |
| | Semaphorin interactions REACT:R-HSA-373755 |
| | SeMet incorporation into proteins REACT:R-HSA-2408517 |
| | Senescence-Associated Secretory Phenotype (SASP) REACT:R-HSA-2559582 |
| | Sensing of DNA Double Strand Breaks REACT:R-HSA-5693548 |
| | Separation of Sister Chromatids REACT:R-HSA-2467813 |
| | Serine biosynthesis REACT:R-HSA-977347 |
| | Serine biosynthesis, glycerate-3P => serine KEGG:hsa_M00020 |
| | Serotonergic synapse KEGG:hsa04726 |
| | Serotonin and melatonin biosynthesis REACT:R-HSA-209931 |
| | Serotonin clearance from the synaptic cleft REACT:R-HSA-380615 |
| | Serotonin Neurotransmitter Release Cycle REACT:R-HSA-181429 |
| | Serotonin receptors REACT:R-HSA-390666 |
| | Severe congenital neutropenia type 4 (G6PC3) REACT:R-HSA-3282872 |
| | SHC1 events in EGFR signaling REACT:R-HSA-180336 |
| | SHC1 events in ERBB2 signaling REACT:R-HSA-1250196 |
| | SHC1 events in ERBB4 signaling REACT:R-HSA-1250347 |
| | SHC-mediated cascade:FGFR1 REACT:R-HSA-5654688 |
| | SHC-mediated cascade:FGFR2 REACT:R-HSA-5654699 |
| | SHC-mediated cascade:FGFR3 REACT:R-HSA-5654704 |
| | SHC-mediated cascade:FGFR4 REACT:R-HSA-5654719 |
| | SHC-related events triggered by IGF1R REACT:R-HSA-2428933 |
| | Shelterin complex KEGG:hsa_M00424 |
| | Shigellosis KEGG:hsa05131 |
| | Sialic acid metabolism REACT:R-HSA-4085001 |
| | Signal amplification REACT:R-HSA-392518 |
| | Signal attenuation REACT:R-HSA-74749 |
| | Signaling by activated point mutants of FGFR1 REACT:R-HSA-1839122 |
| | Signaling by activated point mutants of FGFR3 REACT:R-HSA-1839130 |
| | Signaling by Activin REACT:R-HSA-1502540 |
| | Signaling by BMP REACT:R-HSA-201451 |
| | Signaling by BRAF and RAF fusions REACT:R-HSA-6802952 |
| | Signaling by cytosolic FGFR1 fusion mutants REACT:R-HSA-1839117 |
| | Signaling by EGFR REACT:R-HSA-177929 |
| | Signaling by EGFR in Cancer REACT:R-HSA-1643713 |
| | Signaling by EGFRvIII in Cancer REACT:R-HSA-5637812 |
| | Signaling by ERBB2 REACT:R-HSA-1227986 |
| | Signaling by ERBB4 REACT:R-HSA-1236394 |
| | Signaling by FGFR REACT:R-HSA-190236 |
| | Signaling by FGFR1 REACT:R-HSA-5654736 |
| | Signaling by FGFR1 amplification mutants REACT:R-HSA-1839120 |
| | Signaling by FGFR1 in disease REACT:R-HSA-5655302 |
| | Signaling by FGFR2 REACT:R-HSA-5654738 |
| | Signaling by FGFR2 amplification mutants REACT:R-HSA-2023837 |
| | Signaling by FGFR2 fusions REACT:R-HSA-8853333 |
| | Signaling by FGFR2 IIIa TM REACT:R-HSA-8851708 |
| | Signaling by FGFR2 in disease REACT:R-HSA-5655253 |
| | Signaling by FGFR3 REACT:R-HSA-5654741 |
| | Signaling by FGFR3 fusions in cancer REACT:R-HSA-8853334 |
| | Signaling by FGFR3 in disease REACT:R-HSA-5655332 |
| | Signaling by FGFR3 point mutants in cancer REACT:R-HSA-8853338 |
| | Signaling by FGFR4 REACT:R-HSA-5654743 |
| | Signaling by FGFR4 in disease REACT:R-HSA-5655291 |
| | Signaling by FGFR in disease REACT:R-HSA-1226099 |
| | Signaling by GPCR REACT:R-HSA-372790 |
| | Signaling by Hedgehog REACT:R-HSA-5358351 |
| | Signaling by high-kinase activity BRAF mutants REACT:R-HSA-6802948 |
| | Signaling by Hippo REACT:R-HSA-2028269 |
| | Signaling by Insulin receptor REACT:R-HSA-74752 |
| | Signaling by Interleukins REACT:R-HSA-449147 |
| | Signaling by Leptin REACT:R-HSA-2586552 |
| | Signaling by Ligand-Responsive EGFR Variants in Cancer REACT:R-HSA-5637815 |
| | Signaling by MET REACT:R-HSA-6806834 |
| | Signaling by moderate kinase activity BRAF mutants REACT:R-HSA-6802946 |
| | Signaling by MST1 REACT:R-HSA-8852405 |
| | Signaling by NODAL REACT:R-HSA-1181150 |
| | Signaling by NOTCH REACT:R-HSA-157118 |
| | Signaling by NOTCH1 REACT:R-HSA-1980143 |
| | Signaling by NOTCH1 HD Domain Mutants in Cancer REACT:R-HSA-2691230 |
| | Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer REACT:R-HSA-2894858 |
| | Signaling by NOTCH1 in Cancer REACT:R-HSA-2644603 |
| | Signaling by NOTCH1 PEST Domain Mutants in Cancer REACT:R-HSA-2644602 |
| | Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant REACT:R-HSA-2660825 |
| | Signaling by NOTCH2 REACT:R-HSA-1980145 |
| | Signaling by NOTCH3 REACT:R-HSA-1980148 |
| | Signaling by NOTCH4 REACT:R-HSA-1980150 |
| | Signaling by Overexpressed Wild-Type EGFR in Cancer REACT:R-HSA-5638302 |
| | Signaling by PDGF REACT:R-HSA-186797 |
| | Signaling by plasma membrane FGFR1 fusions REACT:R-HSA-8853336 |
| | Signaling by PTK6 REACT:R-HSA-8848021 |
| | Signaling by RAS mutants REACT:R-HSA-6802949 |
| | Signaling by Retinoic Acid REACT:R-HSA-5362517 |
| | Signaling by Rho GTPases REACT:R-HSA-194315 |
| | Signaling by Robo receptor REACT:R-HSA-376176 |
| | Signaling by SCF-KIT REACT:R-HSA-1433557 |
| | Signaling by TGF-beta Receptor Complex REACT:R-HSA-170834 |
| | Signaling by TGF-beta Receptor Complex in Cancer REACT:R-HSA-3304351 |
| | Signaling by the B Cell Receptor (BCR) REACT:R-HSA-983705 |
| | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) REACT:R-HSA-2404192 |
| | Signaling by VEGF REACT:R-HSA-194138 |
| | Signaling by Wnt REACT:R-HSA-195721 |
| | Signaling by WNT in cancer REACT:R-HSA-4791275 |
| | Signaling pathways regulating pluripotency of stem cells KEGG:hsa04550 |
| | Signalling by NGF REACT:R-HSA-166520 |
| | Signalling to ERK5 REACT:R-HSA-198765 |
| | Signalling to ERKs REACT:R-HSA-187687 |
| | Signalling to p38 via RIT and RIN REACT:R-HSA-187706 |
| | Signalling to RAS REACT:R-HSA-167044 |
| | Signalling to STAT3 REACT:R-HSA-198745 |
| | Signal regulatory protein (SIRP) family interactions REACT:R-HSA-391160 |
| | Signal Transduction REACT:R-HSA-162582 |
| | Signal transduction by L1 REACT:R-HSA-445144 |
| | SIRT1 negatively regulates rRNA Expression REACT:R-HSA-427359 |
| | Ski complex KEGG:hsa_M00392 |
| | SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs REACT:R-HSA-77588 |
| | SLBP independent Processing of Histone Pre-mRNAs REACT:R-HSA-111367 |
| | SLC-mediated transmembrane transport REACT:R-HSA-425407 |
| | SLC transporter disorders REACT:R-HSA-5619102 |
| | SMAC binds to IAPs REACT:R-HSA-111463 |
| | SMAC-mediated apoptotic response REACT:R-HSA-111469 |
| | SMAC-mediated dissociation of IAP:caspase complexes REACT:R-HSA-111464 |
| | SMAD2/3 MH2 Domain Mutants in Cancer REACT:R-HSA-3315487 |
| | SMAD2/3 Phosphorylation Motif Mutants in Cancer REACT:R-HSA-3304356 |
| | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription REACT:R-HSA-2173796 |
| | SMAD4 MH2 Domain Mutants in Cancer REACT:R-HSA-3311021 |
| | Small cell lung cancer KEGG:hsa05222 |
| | Small interfering RNA (siRNA) biogenesis REACT:R-HSA-426486 |
| | Sm core complex KEGG:hsa_M00398 |
| | Smooth Muscle Contraction REACT:R-HSA-445355 |
| | SNARE interactions in vesicular transport KEGG:hsa04130 |
| | snRNP Assembly REACT:R-HSA-191859 |
| | Sodium/Calcium exchangers REACT:R-HSA-425561 |
| | Sodium-coupled phosphate cotransporters REACT:R-HSA-427652 |
| | Sodium-coupled sulphate, di- and tri-carboxylate transporters REACT:R-HSA-433137 |
| | Sodium/Proton exchangers REACT:R-HSA-425986 |
| | SOS-mediated signalling REACT:R-HSA-112412 |
| | Sperm Motility And Taxes REACT:R-HSA-1300642 |
| | Sperm:Oocyte Membrane Binding REACT:R-HSA-1300652 |
| | S Phase REACT:R-HSA-69242 |
| | Sphingolipid de novo biosynthesis REACT:R-HSA-1660661 |
| | Sphingolipid metabolism KEGG:hsa00600 |
| | Sphingolipid metabolism REACT:R-HSA-428157 |
| | Sphingolipid signaling pathway KEGG:hsa04071 |
| | Sphingosine biosynthesis KEGG:hsa_M00099 |
| | Sphingosine degradation KEGG:hsa_M00100 |
| | Spliceosome KEGG:hsa03040 |
| | Spliceosome, 35S U5-snRNP KEGG:hsa_M00355 |
| | Spliceosome, Prp19/CDC5L complex KEGG:hsa_M00353 |
| | Spliceosome, U1-snRNP KEGG:hsa_M00351 |
| | Spliceosome, U2-snRNP KEGG:hsa_M00352 |
| | Spliceosome, U4/U6.U5 tri-snRNP KEGG:hsa_M00354 |
| | Spry regulation of FGF signaling REACT:R-HSA-1295596 |
| | SRP-dependent cotranslational protein targeting to membrane REACT:R-HSA-1799339 |
| | Stabilization of p53 REACT:R-HSA-69541 |
| | Staphylococcus aureus infection KEGG:hsa05150 |
| | Starch and sucrose metabolism KEGG:hsa00500 |
| | STAT6-mediated induction of chemokines REACT:R-HSA-3249367 |
| | Steroid biosynthesis KEGG:hsa00100 |
| | Steroid hormone biosynthesis KEGG:hsa00140 |
| | Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone KEGG:hsa_M00107 |
| | Sterols are 12-hydroxylated by CYP8B1 REACT:R-HSA-211994 |
| | Stimulation of the cell death response by PAK-2p34 REACT:R-HSA-211736 |
| | Stimuli-sensing channels REACT:R-HSA-2672351 |
| | STING mediated induction of host immune responses REACT:R-HSA-1834941 |
| | Striated Muscle Contraction REACT:R-HSA-390522 |
| | Succinate dehydrogenase (ubiquinone) KEGG:hsa_M00148 |
| | Sulfide oxidation to sulfate REACT:R-HSA-1614517 |
| | Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid KEGG:hsa_M00067 |
| | Sulfur amino acid metabolism REACT:R-HSA-1614635 |
| | Sulfur metabolism KEGG:hsa00920 |
| | Sulfur relay system KEGG:hsa04122 |
| | SUMO E3 ligases SUMOylate target proteins REACT:R-HSA-3108232 |
| | SUMO is conjugated to E1 (UBA2:SAE1) REACT:R-HSA-3065676 |
| | SUMO is proteolytically processed REACT:R-HSA-3065679 |
| | SUMO is transferred from E1 to E2 (UBE2I, UBC9) REACT:R-HSA-3065678 |
| | SUMOylation REACT:R-HSA-2990846 |
| | SUMOylation of chromatin organization proteins REACT:R-HSA-4551638 |
| | SUMOylation of DNA damage response and repair proteins REACT:R-HSA-3108214 |
| | SUMOylation of DNA replication proteins REACT:R-HSA-4615885 |
| | SUMOylation of RNA binding proteins REACT:R-HSA-4570464 |
| | SUMOylation of transcription factors REACT:R-HSA-3232118 |
| | Surfactant metabolism REACT:R-HSA-5683826 |
| | Survival motor neuron (SMN) complex KEGG:hsa_M00426 |
| | Switching of origins to a post-replicative state REACT:R-HSA-69052 |
| | Synaptic vesicle cycle KEGG:hsa04721 |
| | Syndecan interactions REACT:R-HSA-3000170 |
| | Synthesis and degradation of ketone bodies KEGG:hsa00072 |
| | Synthesis and interconversion of nucleotide di- and triphosphates REACT:R-HSA-499943 |
| | Synthesis and processing of ENV and VPU REACT:R-HSA-171286 |
| | Synthesis And Processing Of GAG, GAGPOL Polyproteins REACT:R-HSA-174495 |
| | Synthesis of 12-eicosatetraenoic acid derivatives REACT:R-HSA-2142712 |
| | Synthesis of 15-eicosatetraenoic acid derivatives REACT:R-HSA-2142770 |
| | Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) REACT:R-HSA-2142816 |
| | Synthesis of 5-eicosatetraenoic acids REACT:R-HSA-2142688 |
| | Synthesis of active ubiquitin: roles of E1 and E2 enzymes REACT:R-HSA-8866652 |
| | Synthesis of bile acids and bile salts REACT:R-HSA-192105 |
| | Synthesis of bile acids and bile salts via 24-hydroxycholesterol REACT:R-HSA-193775 |
| | Synthesis of bile acids and bile salts via 27-hydroxycholesterol REACT:R-HSA-193807 |
| | Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol REACT:R-HSA-193368 |
| | Synthesis of BMP REACT:R-HSA-1483171 |
| | Synthesis of CL REACT:R-HSA-1483076 |
| | Synthesis of diphthamide-EEF2 REACT:R-HSA-5358493 |
| | Synthesis of DNA REACT:R-HSA-69239 |
| | Synthesis of Dolichyl-phosphate REACT:R-HSA-446199 |
| | Synthesis of dolichyl-phosphate-glucose REACT:R-HSA-480985 |
| | Synthesis of dolichyl-phosphate mannose REACT:R-HSA-162699 |
| | Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) REACT:R-HSA-2142670 |
| | Synthesis of GDP-mannose REACT:R-HSA-446205 |
| | Synthesis of glycosylphosphatidylinositol (GPI) REACT:R-HSA-162710 |
| | Synthesis of Hepoxilins (HX) and Trioxilins (TrX) REACT:R-HSA-2142696 |
| | Synthesis of IP2, IP, and Ins in the cytosol REACT:R-HSA-1855183 |
| | Synthesis of IP3 and IP4 in the cytosol REACT:R-HSA-1855204 |
| | Synthesis of IPs in the ER lumen REACT:R-HSA-1855231 |
| | Synthesis of IPs in the nucleus REACT:R-HSA-1855191 |
| | Synthesis of Ketone Bodies REACT:R-HSA-77111 |
| | Synthesis of Leukotrienes (LT) and Eoxins (EX) REACT:R-HSA-2142691 |
| | Synthesis of Lipoxins (LX) REACT:R-HSA-2142700 |
| | Synthesis of PA REACT:R-HSA-1483166 |
| | Synthesis of PC REACT:R-HSA-1483191 |
| | Synthesis of PE REACT:R-HSA-1483213 |
| | Synthesis of PG REACT:R-HSA-1483148 |
| | Synthesis of PI REACT:R-HSA-1483226 |
| | Synthesis of PIPs at the early endosome membrane REACT:R-HSA-1660516 |
| | Synthesis of PIPs at the ER membrane REACT:R-HSA-1483248 |
| | Synthesis of PIPs at the Golgi membrane REACT:R-HSA-1660514 |
| | Synthesis of PIPs at the late endosome membrane REACT:R-HSA-1660517 |
| | Synthesis of PIPs at the plasma membrane REACT:R-HSA-1660499 |
| | Synthesis of PIPs in the nucleus REACT:R-HSA-8847453 |
| | Synthesis of Prostaglandins (PG) and Thromboxanes (TX) REACT:R-HSA-2162123 |
| | Synthesis of PS REACT:R-HSA-1483101 |
| | Synthesis of pyrophosphates in the cytosol REACT:R-HSA-1855167 |
| | Synthesis of substrates in N-glycan biosythesis REACT:R-HSA-446219 |
| | Synthesis of UDP-N-acetyl-glucosamine REACT:R-HSA-446210 |
| | Synthesis of very long-chain fatty acyl-CoAs REACT:R-HSA-75876 |
| | Synthesis of wybutosine at G37 of tRNA(Phe) REACT:R-HSA-6782861 |
| | Synthesis, secretion, and deacylation of Ghrelin REACT:R-HSA-422085 |
| | Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) REACT:R-HSA-381771 |
| | Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) REACT:R-HSA-400511 |
| | Systemic lupus erythematosus KEGG:hsa05322 |
| | t(4;14) translocations of FGFR3 REACT:R-HSA-2033515 |
| | T41 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358752 |
| | Tachykinin receptors bind tachykinins REACT:R-HSA-380095 |
| | TAK1 activates NFkB by phosphorylation and activation of IKKs complex REACT:R-HSA-445989 |
| | TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P REACT:R-HSA-6791462 |
| | TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P REACT:R-HSA-6791055 |
| | Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) REACT:R-HSA-1299308 |
| | Tandem pore domain halothane-inhibited K+ channel (THIK) REACT:R-HSA-1299287 |
| | Tandem pore domain potassium channels REACT:R-HSA-1296346 |
| | Taste transduction KEGG:hsa04742 |
| | Tat-mediated elongation of the HIV-1 transcript REACT:R-HSA-167246 |
| | Tat-mediated HIV elongation arrest and recovery REACT:R-HSA-167243 |
| | Taurine and hypotaurine metabolism KEGG:hsa00430 |
| | TBC/RABGAPs REACT:R-HSA-8854214 |
| | T cell receptor signaling pathway KEGG:hsa04660 |
| | TCF7L2 mutants don't bind CTBP REACT:R-HSA-5339700 |
| | TCF dependent signaling in response to WNT REACT:R-HSA-201681 |
| | TCR signaling REACT:R-HSA-202403 |
| | Telomere C-strand (Lagging Strand) Synthesis REACT:R-HSA-174417 |
| | Telomere C-strand synthesis initiation REACT:R-HSA-174430 |
| | Telomere Extension By Telomerase REACT:R-HSA-171319 |
| | Telomere Maintenance REACT:R-HSA-157579 |
| | Terminal pathway of complement REACT:R-HSA-166665 |
| | Termination of O-glycan biosynthesis REACT:R-HSA-977068 |
| | Termination of translesion DNA synthesis REACT:R-HSA-5656169 |
| | Terpenoid backbone biosynthesis KEGG:hsa00900 |
| | TET1,2,3 and TDG demethylate DNA REACT:R-HSA-5221030 |
| | Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation REACT:R-HSA-1474151 |
| | TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation REACT:R-HSA-8869496 |
| | TFAP2 (AP-2) family regulates transcription of cell cycle factors REACT:R-HSA-8866911 |
| | TFAP2 (AP-2) family regulates transcription of growth factors and their receptors REACT:R-HSA-8866910 |
| | TFAP2 (AP-2) family regulates transcription of other transcription factors REACT:R-HSA-8866906 |
| | TGF-beta receptor signaling activates SMADs REACT:R-HSA-2173789 |
| | TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) REACT:R-HSA-2173791 |
| | TGF-beta signaling KEGG:hsa_M00680 |
| | TGF-beta signaling pathway KEGG:hsa04350 |
| | TGFBR1 KD Mutants in Cancer REACT:R-HSA-3656532 |
| | TGFBR1 LBD Mutants in Cancer REACT:R-HSA-3656535 |
| | TGFBR2 Kinase Domain Mutants in Cancer REACT:R-HSA-3645790 |
| | TGFBR2 MSI Frameshift Mutants in Cancer REACT:R-HSA-3642279 |
| | Th17 cell differentiation KEGG:hsa04659 |
| | Th1 and Th2 cell differentiation KEGG:hsa04658 |
| | THC complex KEGG:hsa_M00405 |
| | The activation of arylsulfatases REACT:R-HSA-1663150 |
| | The AIM2 inflammasome REACT:R-HSA-844615 |
| | The canonical retinoid cycle in rods (twilight vision) REACT:R-HSA-2453902 |
| | The citric acid (TCA) cycle and respiratory electron transport REACT:R-HSA-1428517 |
| | The fatty acid cycling model REACT:R-HSA-167826 |
| | The IPAF inflammasome REACT:R-HSA-844623 |
| | The NLRP1 inflammasome REACT:R-HSA-844455 |
| | The NLRP3 inflammasome REACT:R-HSA-844456 |
| | The phototransduction cascade REACT:R-HSA-2514856 |
| | The proton buffering model REACT:R-HSA-167827 |
| | The retinoid cycle in cones (daylight vision) REACT:R-HSA-2187335 |
| | The role of GTSE1 in G2/M progression after G2 checkpoint REACT:R-HSA-8852276 |
| | The role of Nef in HIV-1 replication and disease pathogenesis REACT:R-HSA-164952 |
| | Thiamine metabolism KEGG:hsa00730 |
| | Threonine catabolism REACT:R-HSA-8849175 |
| | Thrombin signalling through proteinase activated receptors (PARs) REACT:R-HSA-456926 |
| | Thromboxane signalling through TP receptor REACT:R-HSA-428930 |
| | Thyroid cancer KEGG:hsa05216 |
| | Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine KEGG:hsa_M00043 |
| | Thyroid hormone signaling pathway KEGG:hsa04919 |
| | Thyroid hormone synthesis KEGG:hsa04918 |
| | Thyroxine biosynthesis REACT:R-HSA-209968 |
| | TICAM1 deficiency - HSE REACT:R-HSA-5602566 |
| | Tie2 Signaling REACT:R-HSA-210993 |
| | Tight junction KEGG:hsa04530 |
| | Tight junction interactions REACT:R-HSA-420029 |
| | TLR3 deficiency - HSE REACT:R-HSA-5602410 |
| | TNFR1-induced NFkappaB signaling pathway REACT:R-HSA-5357956 |
| | TNFR1-induced proapoptotic signaling REACT:R-HSA-5357786 |
| | TNFR1-mediated ceramide production REACT:R-HSA-5626978 |
| | TNFR2 non-canonical NF-kB pathway REACT:R-HSA-5668541 |
| | TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway REACT:R-HSA-5676594 |
| | TNFs bind their physiological receptors REACT:R-HSA-5669034 |
| | TNF signaling REACT:R-HSA-75893 |
| | TNF signaling pathway KEGG:hsa04668 |
| | Tolerance by Mtb to nitric oxide produced by macrophages REACT:R-HSA-1222538 |
| | Tolerance of reactive oxygen produced by macrophages REACT:R-HSA-1222387 |
| | Toll Like Receptor 10 (TLR10) Cascade REACT:R-HSA-168142 |
| | Toll Like Receptor 2 (TLR2) Cascade REACT:R-HSA-181438 |
| | Toll Like Receptor 3 (TLR3) Cascade REACT:R-HSA-168164 |
| | Toll Like Receptor 4 (TLR4) Cascade REACT:R-HSA-166016 |
| | Toll Like Receptor 5 (TLR5) Cascade REACT:R-HSA-168176 |
| | Toll Like Receptor 7/8 (TLR7/8) Cascade REACT:R-HSA-168181 |
| | Toll Like Receptor 9 (TLR9) Cascade REACT:R-HSA-168138 |
| | Toll-Like Receptors Cascades REACT:R-HSA-168898 |
| | Toll-like receptor signaling KEGG:hsa_M00686 |
| | Toll-like receptor signaling pathway KEGG:hsa04620 |
| | Toll Like Receptor TLR1:TLR2 Cascade REACT:R-HSA-168179 |
| | Toll Like Receptor TLR6:TLR2 Cascade REACT:R-HSA-168188 |
| | Toxicity of botulinum toxin type A (BoNT/A) REACT:R-HSA-5250968 |
| | Toxicity of botulinum toxin type B (BoNT/B) REACT:R-HSA-5250958 |
| | Toxicity of botulinum toxin type C (BoNT/C) REACT:R-HSA-5250971 |
| | Toxicity of botulinum toxin type D (BoNT/D) REACT:R-HSA-5250955 |
| | Toxicity of botulinum toxin type E (BoNT/E) REACT:R-HSA-5250992 |
| | Toxicity of botulinum toxin type F (BoNT/F) REACT:R-HSA-5250981 |
| | Toxicity of botulinum toxin type G (BoNT/G) REACT:R-HSA-5250989 |
| | Toxicity of tetanus toxin (TeNT) REACT:R-HSA-5250982 |
| | Toxoplasmosis KEGG:hsa05145 |
| | TP53 Regulates Metabolic Genes REACT:R-HSA-5628897 |
| | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain REACT:R-HSA-6804115 |
| | TP53 Regulates Transcription of Caspase Activators and Caspases REACT:R-HSA-6803207 |
| | TP53 Regulates Transcription of Cell Cycle Genes REACT:R-HSA-6791312 |
| | TP53 Regulates Transcription of Cell Death Genes REACT:R-HSA-5633008 |
| | TP53 Regulates Transcription of Death Receptors and Ligands REACT:R-HSA-6803211 |
| | TP53 Regulates Transcription of DNA Repair Genes REACT:R-HSA-6796648 |
| | TP53 Regulates Transcription of Genes Involved in Cytochrome C Release REACT:R-HSA-6803204 |
| | TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest REACT:R-HSA-6804116 |
| | TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest REACT:R-HSA-6804114 |
| | TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain REACT:R-HSA-6803205 |
| | TRAF3 deficiency - HSE REACT:R-HSA-5602571 |
| | TRAF3-dependent IRF activation pathway REACT:R-HSA-918233 |
| | TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation REACT:R-HSA-975138 |
| | TRAF6 mediated induction of TAK1 complex REACT:R-HSA-937072 |
| | TRAF6 mediated IRF7 activation REACT:R-HSA-933541 |
| | TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling REACT:R-HSA-975110 |
| | TRAF6 mediated NF-kB activation REACT:R-HSA-933542 |
| | Trafficking and processing of endosomal TLR REACT:R-HSA-1679131 |
| | Trafficking of AMPA receptors REACT:R-HSA-399719 |
| | Trafficking of dietary sterols REACT:R-HSA-265473 |
| | Trafficking of GluR2-containing AMPA receptors REACT:R-HSA-416993 |
| | Trafficking of myristoylated proteins to the cilium REACT:R-HSA-5624138 |
| | TRAIL signaling REACT:R-HSA-75158 |
| | TRAMP complex KEGG:hsa_M00393 |
| | Transcriptional activation of cell cycle inhibitor p21 REACT:R-HSA-69895 |
| | Transcriptional activation of mitochondrial biogenesis REACT:R-HSA-2151201 |
| | Transcriptional activation of p53 responsive genes REACT:R-HSA-69560 |
| | Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer REACT:R-HSA-2173793 |
| | Transcriptional misregulation in cancer KEGG:hsa05202 |
| | Transcriptional regulation by small RNAs REACT:R-HSA-5578749 |
| | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors REACT:R-HSA-8864260 |
| | Transcriptional Regulation by TP53 REACT:R-HSA-3700989 |
| | Transcriptional regulation of pluripotent stem cells REACT:R-HSA-452723 |
| | Transcriptional regulation of white adipocyte differentiation REACT:R-HSA-381340 |
| | Transcription-Coupled Nucleotide Excision Repair (TC-NER) REACT:R-HSA-6781827 |
| | Transcription from mitochondrial promoters REACT:R-HSA-75944 |
| | Transcription of the HIV genome REACT:R-HSA-167172 |
| | Transfer of LPS from LBP carrier to CD14 REACT:R-HSA-166020 |
| | Transferrin endocytosis and recycling REACT:R-HSA-917977 |
| | trans-Golgi Network Vesicle Budding REACT:R-HSA-199992 |
| | Translation REACT:R-HSA-72766 |
| | Translation initiation complex formation REACT:R-HSA-72649 |
| | Translesion Synthesis by POLH REACT:R-HSA-110320 |
| | Translesion synthesis by POLI REACT:R-HSA-5656121 |
| | Translesion synthesis by POLK REACT:R-HSA-5655862 |
| | Translesion synthesis by REV1 REACT:R-HSA-110312 |
| | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template REACT:R-HSA-110313 |
| | Translocation of GLUT4 to the plasma membrane REACT:R-HSA-1445148 |
| | Translocation of ZAP-70 to Immunological synapse REACT:R-HSA-202430 |
| | Translocon-associated protein (TRAP) complex KEGG:hsa_M00402 |
| | Transmembrane transport of small molecules REACT:R-HSA-382551 |
| | Transmission across Chemical Synapses REACT:R-HSA-112315 |
| | Transmission across Electrical Synapses REACT:R-HSA-112307 |
| | Transport and synthesis of PAPS REACT:R-HSA-174362 |
| | Transport of connexins along the secretory pathway REACT:R-HSA-190827 |
| | Transport of connexons to the plasma membrane REACT:R-HSA-190872 |
| | Transport of fatty acids REACT:R-HSA-804914 |
| | Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus REACT:R-HSA-159763 |
| | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds REACT:R-HSA-425366 |
| | Transport of glycerol from adipocytes to the liver by Aquaporins REACT:R-HSA-432030 |
| | Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus REACT:R-HSA-168874 |
| | Transport of inorganic cations/anions and amino acids/oligopeptides REACT:R-HSA-425393 |
| | Transport of Mature mRNA derived from an Intron-Containing Transcript REACT:R-HSA-159236 |
| | Transport of Mature mRNA Derived from an Intronless Transcript REACT:R-HSA-159231 |
| | Transport of Mature mRNAs Derived from Intronless Transcripts REACT:R-HSA-159234 |
| | Transport of Mature Transcript to Cytoplasm REACT:R-HSA-72202 |
| | Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane REACT:R-HSA-83936 |
| | Transport of nucleotide sugars REACT:R-HSA-727802 |
| | Transport of organic anions REACT:R-HSA-879518 |
| | Transport of Ribonucleoproteins into the Host Nucleus REACT:R-HSA-168271 |
| | Transport of the SLBP Dependant Mature mRNA REACT:R-HSA-159230 |
| | Transport of the SLBP independent Mature mRNA REACT:R-HSA-159227 |
| | Transport of vitamins, nucleosides, and related molecules REACT:R-HSA-425397 |
| | Transport to the Golgi and subsequent modification REACT:R-HSA-948021 |
| | TREX complex KEGG:hsa_M00406 |
| | Triacylglycerol biosynthesis KEGG:hsa_M00089 |
| | TRIF-mediated programmed cell death REACT:R-HSA-2562578 |
| | TRIF-mediated TLR3/TLR4 signaling REACT:R-HSA-937061 |
| | Triglyceride Biosynthesis REACT:R-HSA-75109 |
| | Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA REACT:R-HSA-450513 |
| | TRKA activation by NGF REACT:R-HSA-187042 |
| | tRNA Aminoacylation REACT:R-HSA-379724 |
| | tRNA modification in the mitochondrion REACT:R-HSA-6787450 |
| | tRNA modification in the nucleus and cytosol REACT:R-HSA-6782315 |
| | tRNA processing REACT:R-HSA-72306 |
| | tRNA processing in the mitochondrion REACT:R-HSA-6785470 |
| | tRNA processing in the nucleus REACT:R-HSA-6784531 |
| | TRP channels REACT:R-HSA-3295583 |
| | truncated APC mutants destabilize the destruction complex REACT:R-HSA-4839744 |
| | Truncations of AMER1 destabilize the destruction complex REACT:R-HSA-5467348 |
| | Tryptophan catabolism REACT:R-HSA-71240 |
| | Tryptophan metabolism KEGG:hsa00380 |
| | Tuberculosis KEGG:hsa05152 |
| | TWIK-related alkaline pH activated K+ channel (TALK) REACT:R-HSA-1299361 |
| | TWIK related potassium channel (TREK) REACT:R-HSA-1299503 |
| | TWIK-related spinal cord K+ channel (TRESK) REACT:R-HSA-1299344 |
| | TWIK-releated acid-sensitive K+ channel (TASK) REACT:R-HSA-1299316 |
| | Type I diabetes mellitus KEGG:hsa04940 |
| | Type I hemidesmosome assembly REACT:R-HSA-446107 |
| | Type II diabetes mellitus KEGG:hsa04930 |
| | Type II Na+/Pi cotransporters REACT:R-HSA-427589 |
| | Tyrosine degradation, tyrosine => homogentisate KEGG:hsa_M00044 |
| | Tyrosine metabolism KEGG:hsa00350 |
| | Ubiquinol biosynthesis REACT:R-HSA-2142789 |
| | Ubiquinone and other terpenoid-quinone biosynthesis KEGG:hsa00130 |
| | Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone KEGG:hsa_M00128 |
| | Ubiquitin-dependent degradation of Cyclin D REACT:R-HSA-75815 |
| | Ubiquitin-dependent degradation of Cyclin D1 REACT:R-HSA-69229 |
| | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A REACT:R-HSA-69601 |
| | Ubiquitin mediated proteolysis KEGG:hsa04120 |
| | Ub-specific processing proteases REACT:R-HSA-5689880 |
| | UCH proteinases REACT:R-HSA-5689603 |
| | Unblocking of NMDA receptor, glutamate binding and activation REACT:R-HSA-438066 |
| | UNC93B1 deficiency - HSE REACT:R-HSA-5602415 |
| | Uncoating of the HIV Virion REACT:R-HSA-162585 |
| | Uncoating of the Influenza Virion REACT:R-HSA-168336 |
| | Unfolded Protein Response (UPR) REACT:R-HSA-381119 |
| | Unwinding of DNA REACT:R-HSA-176974 |
| | Uptake and actions of bacterial toxins REACT:R-HSA-5339562 |
| | Uptake and function of anthrax toxins REACT:R-HSA-5210891 |
| | Uptake and function of diphtheria toxin REACT:R-HSA-5336415 |
| | Urea cycle KEGG:hsa_M00029 |
| | Urea cycle REACT:R-HSA-70635 |
| | Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP KEGG:hsa_M00051 |
| | Utilization of Ketone Bodies REACT:R-HSA-77108 |
| | Valine, leucine and isoleucine biosynthesis KEGG:hsa00290 |
| | Valine, leucine and isoleucine degradation KEGG:hsa00280 |
| | Variant SLC6A14 may confer susceptibility towards obesity REACT:R-HSA-5619094 |
| | Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) REACT:R-HSA-5619101 |
| | Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) REACT:R-HSA-5660686 |
| | Vascular smooth muscle contraction KEGG:hsa04270 |
| | Vasopressin-like receptors REACT:R-HSA-388479 |
| | Vasopressin-regulated water reabsorption KEGG:hsa04962 |
| | Vasopressin regulates renal water homeostasis via Aquaporins REACT:R-HSA-432040 |
| | VEGFA-VEGFR2 Pathway REACT:R-HSA-4420097 |
| | VEGF binds to VEGFR leading to receptor dimerization REACT:R-HSA-195399 |
| | VEGF ligand-receptor interactions REACT:R-HSA-194313 |
| | VEGFR2 mediated cell proliferation REACT:R-HSA-5218921 |
| | VEGFR2 mediated vascular permeability REACT:R-HSA-5218920 |
| | VEGF signaling pathway KEGG:hsa04370 |
| | Vesicle-mediated transport REACT:R-HSA-5653656 |
| | Vibrio cholerae infection KEGG:hsa05110 |
| | Vif-mediated degradation of APOBEC3G REACT:R-HSA-180585 |
| | Viral carcinogenesis KEGG:hsa05203 |
| | Viral Messenger RNA Synthesis REACT:R-HSA-168325 |
| | Viral mRNA Translation REACT:R-HSA-192823 |
| | Viral myocarditis KEGG:hsa05416 |
| | Viral RNP Complexes in the Host Cell Nucleus REACT:R-HSA-168330 |
| | Virus Assembly and Release REACT:R-HSA-168268 |
| | Visual phototransduction REACT:R-HSA-2187338 |
| | Vitamin B1 (thiamin) metabolism REACT:R-HSA-196819 |
| | Vitamin B2 (riboflavin) metabolism REACT:R-HSA-196843 |
| | Vitamin B5 (pantothenate) metabolism REACT:R-HSA-199220 |
| | Vitamin B6 metabolism KEGG:hsa00750 |
| | Vitamin C (ascorbate) metabolism REACT:R-HSA-196836 |
| | Vitamin D (calciferol) metabolism REACT:R-HSA-196791 |
| | Vitamin digestion and absorption KEGG:hsa04977 |
| | Vitamins REACT:R-HSA-211916 |
| | Vitamins B6 activation to pyridoxal phosphate REACT:R-HSA-964975 |
| | VLDL biosynthesis REACT:R-HSA-8866423 |
| | VLDL interactions REACT:R-HSA-8855121 |
| | VLDLR internalisation and degradation REACT:R-HSA-8866427 |
| | Voltage gated Potassium channels REACT:R-HSA-1296072 |
| | Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization REACT:R-HSA-180897 |
| | Vpr-mediated nuclear import of PICs REACT:R-HSA-180910 |
| | Vpu mediated degradation of CD4 REACT:R-HSA-180534 |
| | vRNA Synthesis REACT:R-HSA-192814 |
| | vRNP Assembly REACT:R-HSA-192905 |
| | V-type ATPase, eukaryotes KEGG:hsa_M00160 |
| | VxPx cargo-targeting to cilium REACT:R-HSA-5620916 |
| | Wax biosynthesis REACT:R-HSA-8848584 |
| | WNT5A-dependent internalization of FZD2, FZD5 and ROR2 REACT:R-HSA-5140745 |
| | WNT5A-dependent internalization of FZD4 REACT:R-HSA-5099900 |
| | WNT ligand biogenesis and trafficking REACT:R-HSA-3238698 |
| | WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 REACT:R-HSA-5340573 |
| | WNT mediated activation of DVL REACT:R-HSA-201688 |
| | Wnt signaling KEGG:hsa_M00677 |
| | Wnt signaling pathway KEGG:hsa04310 |
| | XAV939 inhibits tankyrase, stabilizing AXIN REACT:R-HSA-5545619 |
| | XBP1(S) activates chaperone genes REACT:R-HSA-381038 |
| | Xenobiotics REACT:R-HSA-211981 |
| | YAP1- and WWTR1 (TAZ)-stimulated gene expression REACT:R-HSA-2032785 |
| | ZBP1(DAI) mediated induction of type I IFNs REACT:R-HSA-1606322 |
| | Zinc efflux and compartmentalization by the SLC30 family REACT:R-HSA-435368 |
| | Zinc influx into cells by the SLC39 gene family REACT:R-HSA-442380 |
| | Zinc transporters REACT:R-HSA-435354 |
| | |
