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+ ---
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+ license: cc-by-4.0
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+ task_categories:
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+ - image-segmentation
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+ tags:
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+ - medical
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+ - histopathology
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+ - whole-slide-imaging
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+ - veterinary
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+ - canine
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+ - dermatology
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+ - oncology
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+ size_categories:
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+ - n<1K
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+ ---
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+
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+ # CATCH — CAnine CuTaneous Cancer Histology
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+
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+ 350 whole-slide images of **canine** skin tumors (H&E), covering **7 tumor
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+ subtypes** with dense multi-class region annotations by a veterinary
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+ pathologist. Mirrored for the MedOtter segmentation benchmark.
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+
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+ > Wilm F., Fragoso M., Marzahl C., Qiu J., Puget C., Diehl L., Bertram C.A.,
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+ > Klopfleisch R., Maier A., Breininger K.*, Aubreville M.* —
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+ > *Pan-tumor CAnine cuTaneous Cancer Histology (CATCH) dataset*,
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+ > **Scientific Data** 9, 588 (2022). doi:10.1038/s41597-022-01692-w
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+ >
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+ > Data DOI: [10.7937/TCIA.2M93-FX66](https://doi.org/10.7937/TCIA.2M93-FX66) ·
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+ > Source: [TCIA CATCH collection](https://www.cancerimagingarchive.net/collection/catch/)
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+
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+ ## What this mirror contains — read before using
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+
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+ The originals are 350 Aperio `.svs` slides totalling **522 GB** at 0.2533 µm/px,
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+ distributed by TCIA behind an Aspera plugin. This mirror stores each slide
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+ rendered at the **4 µm/px pyramid level** — the exact resolution the CATCH
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+ paper's own segmentation baseline operates at (512×512 px ≙ 2048×2048 µm) —
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+ as a lossless PNG, paired with a 13-class indexed mask rasterized at the same
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+ level. It is a **derived, downsampled** representation, not the original WSIs.
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+
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+ For full-resolution work, use TCIA. The complete original polygon annotations
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+ are included here as `CATCH.json` so any other pyramid level can be re-derived.
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+
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+ | | |
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+ |---|---|
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+ | Slides | 350 |
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+ | Patients | 282 |
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+ | Resolution | 4.05 µm/px (pyramid level 2, ≈16× downsample, all 350 slides) |
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+ | Image size | median 6025×4644, max 11812×6046, mean 29.7 Mpx |
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+ | Polygons | 12,424 |
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+ | Classes | 13 (+ label 0 = unannotated) |
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+ | Splits | train 245 / val 35 / test 70 (official, patient-level) |
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+
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+ ## Splits
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+
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+ The official split from the authors' [CanineCutaneousTumors](https://github.com/DeepPathology/CanineCutaneousTumors)
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+ repo, balanced at **35 / 5 / 10 slides per subtype**. It is patient-level:
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+ **no patient appears in two splits** (verified across all 282 patients).
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+
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+ A slide's patient is the filename prefix `<Subtype>_<NN>` — 41 patients
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+ contribute 2 slides, 8 contribute 3, 2 contribute 4, and 1 contributes 6.
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+ **Group on `patient_id`, not on `slide`.**
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+
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+ ## Labels
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+
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+ `mask` is a single-channel uint8 PNG. **Label 0 means *unannotated*, not
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+ background** — CATCH has no background class by design, and the authors
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+ exclude unannotated tissue from training and evaluation. Treat 0 as
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+ *don't-care*, or synthesize a background class by Otsu-thresholding the white
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+ point per slide, which is what the paper's baseline does.
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+
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+ | ID | Class | Group | Slides present |
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+ |---|---|---|---|
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+ | 0 | unannotated | — | 350 |
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+ | 1 | Bone | Tissue | 21 |
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+ | 2 | Cartilage | Tissue | 4 |
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+ | 3 | Dermis | Tissue | 322 |
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+ | 4 | Epidermis | Tissue | 321 |
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+ | 5 | Subcutis | Tissue | 246 |
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+ | 6 | Inflamm/Necrosis | Tissue | 149 |
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+ | 7 | Melanoma | Tumor | 50 |
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+ | 8 | Plasmacytoma | Tumor | 50 |
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+ | 9 | Mast Cell Tumor | Tumor | 50 |
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+ | 10 | PNST | Tumor | 50 |
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+ | 11 | SCC | Tumor | 50 |
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+ | 12 | Trichoblastoma | Tumor | 50 |
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+ | 13 | Histiocytoma | Tumor | 50 |
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+
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+ **Bone (21 slides) and Cartilage (4 slides) are too rare for class-averaged
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+ metrics** — the authors exclude both from their own baseline. Do the same.
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+
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+ **Exactly one tumor class occurs per slide**, and it always equals the slide's
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+ subtype (verified 350/350). `tumor_class_id` / `tumor_class_name` give it
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+ directly, so a binary tumor-vs-rest target needs no lookup.
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+
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+ ### Polygons are hierarchical — rasterize in file order
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+
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+ Annotations nest: the dermis encircles a tumor mass, and islands of normal
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+ dermis sit inside the tumor. Masks here are rasterized in **COCO file order**,
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+ which is the authors' documented sort — *"polygons are sorted in increasing
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+ order of their hierarchy level, i.e. polygons enclosed by another will be read
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+ out after their enclosing polygon"* — so a later fill correctly overwrites the
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+ region it sits within.
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+
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+ ⚠️ **Do not sort by the `area` field instead.** `area` is the shoelace area, so
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+ a polygon drawn as a *ring* around a tumor reports a **smaller** area than the
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+ blob it encloses, while a standard polygon fill (`cv2.fillPoly`, `PIL
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+ ImageDraw.polygon`) fills its outer boundary solid. Sorting area-descending
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+ therefore paints the ring last and **buries the tumor completely**. Measured on
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+ this data, it destroys the entire tumor annotation on `Plasmacytoma_08_1`,
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+ `Trichoblastoma_31_2` and `Trichoblastoma_34_1`.
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+
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+ File order reproduces the per-class slide presence of the source polygons
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+ **exactly** for all 13 classes across all 350 slides; area-descending does not.
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+
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+ ## Columns
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+
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+ `image` · `mask` · `slide` · `stem` · `subtype` · `patient_id` · `split` ·
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+ `scanner` · `tumor_class_id` · `tumor_class_name` · `width` · `height` · `mpp` ·
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+ `downsample` �� `level0_width` · `level0_height` · `annotated_frac` ·
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+ `classes_present`
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+
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+ `annotated_frac` is the fraction of canvas carrying a label (median ≈ 0.50;
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+ much of the remainder is glass, not untraced tissue).
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+
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+ ## Overlap with other datasets — leakage warnings
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+
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+ - **Multi-Scanner Canine Cutaneous SCC** ([Zenodo 7418555](https://zenodo.org/records/7418555))
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+ re-scans **44 of CATCH's 50 SCC slides** on 4 additional scanners. Confirmed
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+ by the authors and **joinable by filename**. Do not mix.
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+ - **MIDOG++ / MIDOG 2022 Domain 4** is 50 canine cutaneous mast cell tumor
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+ cases from the same archive, scanner and resolution as CATCH's 50 MCT
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+ slides. The reuse is undocumented and **no cross-reference ID exists** — the
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+ naming schemes are not joinable. Treat the MCT subset as potentially
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+ contaminated if you also use MIDOG.
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+ - **CCMCT / MITOS_WSI_CCMCT** (32 canine cutaneous MCT WSIs) may likewise
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+ overlap the MCT subset. Also unjoinable.
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+ - **No overlap with human histopathology sets** (TCGA-derived, PanNuke,
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+ MoNuSeg, MoNuSAC, NuCLS, CoNIC, CAMELYON, …) — different species.
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+
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+ ⚠️ Web summaries claiming "CATCH is on Zenodo as 4 µm/px TIFFs" are **wrong**;
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+ that record is the 44-slide Multi-Scanner SCC derivative, not CATCH.
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+
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+ ## Annotation provenance
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+
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+ One annotation tier is released. Pathologist **M. Fragoso** drew ~82% of the
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+ annotations; the remainder was drawn by three medical students and then
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+ reviewed for correctness and completeness by M. Fragoso. The distributed
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+ SQLite has exactly one entry in its `Persons` table — a single merged layer,
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+ with no algorithmic pre-annotation. Two further veterinary pathologists
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+ annotated one ROI on each of the 70 test slides for an inter-rater study;
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+ **that data was never published** and is not part of this dataset.
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+
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+ Reported reliability (paper Table 3, generalized conformity index): tumor
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+ 0.8514, epidermis 0.7512. Dermis/subcutis are the weakest pair, and
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+ inflammation/necrosis vs tumor is the other main confusion axis.
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+
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+ ## License
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+
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+ **CC BY 4.0**, as stated for all three data rows on the
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+ [TCIA collection page](https://www.cancerimagingarchive.net/collection/catch/),
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+ the authors' designated distribution channel.
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+
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+ ⚠️ **Discrepancy, disclosed for transparency:** the `licenses` block *inside*
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+ the official `CATCH.json` declares `Attribution-NonCommercial-NoDerivs 2.0`.
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+ This appears to be a COCO-export template default rather than a deliberate
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+ choice, and it is contradicted by TCIA's own Data Access table and by the
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+ CC BY 4.0 paper. We treat the TCIA statement as controlling. If your use is
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+ commercial or derivative-heavy, verify with the authors first.
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+
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+ Users must also abide by the
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+ [TCIA Data Usage Policy](https://www.cancerimagingarchive.net/data-usage-policies-and-restrictions/).
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+ Please cite the paper and the data DOI above.
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+
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+ ## Reproducing this mirror
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+
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+ Level 2 of each remote `.svs` is read via HTTP byte-range requests — a `.svs`
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+ is a pyramidal TIFF, so pulling only that level costs **0.79% of each file
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+ (4.1 GB total instead of 522 GB)** and needs no Aspera client and no login.
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+ `CATCH.json` is then rasterized in file order at the same level.