--- license: cc-by-4.0 language: - en pretty_name: "Roller Compaction: Ribbon Density vs. Process Parameters (Synthetic)" size_categories: - n<1K task_categories: - tabular-regression tags: - roller-compaction - pharmaceutical-manufacturing - design-of-experiments - response-surface-methodology - quality-by-design - synthetic-data - powder-processing - heckel-equation - johanson-model - process-engineering - education configs: - config_name: default data_files: - split: train path: "ribbon_density_v1.0.csv" --- # Roller Compaction: Ribbon Density vs. Process Parameters (Synthetic) **Version:** 1.0 **Publisher:** [Innovative Process Applications (IPA)](https://www.innovativeprocess.com) **License:** Creative Commons Attribution 4.0 International (CC BY 4.0) **Contact:** Crestwood, IL, USA > ⚠️ **This dataset is 100% synthetic and intended for educational use only.** > It was generated from a published physical model (Johanson rolling theory + Heckel densification) — not measured on any real equipment, customer, or production batch. Do not use it for regulatory submissions, equipment validation, or commercial process design. --- ## What's in this dataset 600 simulated roller compaction runs on a representative pharmaceutical excipient blend (microcrystalline cellulose / lactose), spanning the operating envelope of a lab-to-pilot scale twin-feed-screw roller compactor. | Column | Units | Description | |---|---|---| | `run_id` | — | Unique run identifier | | `roll_force_kN_per_cm` | kN/cm | Specific roll force (normalized by roll width) | | `roll_speed_rpm` | rpm | Roll rotation speed | | `feed_screw_rpm` | rpm | Twin feed screw rotation speed | | `roll_gap_mm` | mm | Target ribbon thickness / roll gap | | `peak_pressure_MPa` | MPa | Computed peak nip pressure (Johanson) | | `ribbon_rel_density` | — | Relative density (fraction of true density) | | `ribbon_density_g_cc` | g/cc | Absolute ribbon density | | `ribbon_porosity` | — | 1 − relative density | | `density_CV_percent` | % | Across-width density coefficient of variation (uniformity) | | `throughput_kg_hr` | kg/hr | Mass throughput | ## Realistic ranges (grounded in the literature) The generator uses ranges consistent with published roller compaction studies on MCC/lactose blends: - **Roll force:** 2–14 kN/cm (typical lab/pilot range) - **Roll speed:** 1–12 rpm - **Feed-to-roll speed ratio:** 3–30 (optimum ≈ 11 for twin feed screws on MCC) - **Peak nip pressure:** ~30–200 MPa - **Relative density:** 0.55–0.80 (ribbons below ~0.55 tend to crumble; above ~0.85 you over-compact and lose downstream granulation behavior) - **Material:** true density 1.55 g/cc, bulk density 0.45 g/cc, Heckel K ≈ 0.018 MPa⁻¹ ## Physical model The synthetic data is generated from: 1. **Johanson rolling theory (1965)** — peak nip pressure as a function of roll force, gap, and roll geometry. 2. **Heckel equation** — relative density as a function of applied pressure: `ln(1/(1−D)) = K·P + A`. 3. **Twin feed screw effect** — a Gaussian optimality response centered on feed/roll ratio ≈ 11, penalizing both starved and over-fed nip conditions. This reflects IPA's twin-feed-screw design advantage for maintaining uniform nip feeding. 4. **Realistic measurement noise** (~1.5% on density, proportional noise on uniformity and throughput). Full generator source is in `generate_dataset.py` — reproducible with seed 42. ## What you can teach with it - **DOE / Response Surface Methodology:** fit a quadratic model to ribbon density as a function of roll force, roll speed, and feed screw speed. - **Process optimization:** find the operating window that maximizes density while keeping CV% under a target (e.g., < 3%). - **Regression & ML:** compare linear regression, random forests, and Gaussian processes on a small-but-physical dataset. - **Quality-by-Design (QbD):** illustrate design space, critical process parameters (CPPs), and critical quality attributes (CQAs). ## Cross-links (other places to find this dataset) - **Kaggle:** [(https://www.kaggle.com/innovativeprocapps)] - **Hugging Face Datasets:** [link after publication] - **Zenodo (DOI):** [https://zenodo.org/records/19500776] - **GitHub:** [https://github.com/Innovative-Process-Applications/ipa-datasets/tree/main/ipa-rc-dataset-v1.0] - **IPA website:** https://www.innovativeprocess.com ## About IPA Innovative Process Applications designs and manufactures twin-feed-screw roller compactors, mills, and size-reduction equipment for the pharmaceutical, nutraceutical, chemical, and food industries. Based in Crestwood, Illinois, IPA is a direct OEM alternative to legacy Fitzpatrick Chilsonator and FitzMill systems, with American manufacturing and direct engineer access. Learn more at [innovativeprocess.com](https://www.innovativeprocess.com). ## Citation If you use this dataset in teaching, a notebook, a paper, or a blog post, please cite: > Innovative Process Applications (2026). *Roller Compaction: Ribbon Density vs. Process Parameters (Synthetic), v1.0*. CC BY 4.0. https://www.innovativeprocess.com ## Version history - **v1.0** (April 2026) — Initial release. 600 runs, 4 process parameters, 6 response variables.