cgeorgiaw HF Staff commited on
Commit
1f522bf
·
verified ·
1 Parent(s): 532c6d4

Add closed DNA tags and mutation location text

Browse files
README.md CHANGED
@@ -97,7 +97,7 @@ Dataset-wide provenance summary:
97
  }
98
  ```
99
 
100
- Every prompt sequence is 8,192 bp long. The variant is placed at the final base of the sequence context: `variant_index_0based = 8191`, equivalent to `variant_position_1based = 8192`.
101
 
102
  The `all_tasks` config has 6,000 task rows but 4,000 unique variant keys. The `binary` and `clinvar_levels` configs are two views of the same 2,000 clinical-classification variants; `pathogenic_pairwise` contributes 2,000 additional pathogenic or likely pathogenic variants.
103
 
@@ -214,7 +214,7 @@ excluded_from_benchmark_eval: true
214
 
215
  ### `binary`
216
 
217
- The prompt shows the reference allele, alternate allele, and an 8,192 bp DNA sequence window containing the alternate allele at the final base of the context. The model is asked to answer with exactly one option:
218
 
219
  ```text
220
  benign or likely benign
@@ -225,7 +225,7 @@ This config collapses ClinVar benign/likely-benign labels and pathogenic/likely-
225
 
226
  ### `clinvar_levels`
227
 
228
- This task uses the same sequence prompt style as `binary`, but preserves the retained raw ClinVar label. Allowed answers are:
229
 
230
  ```text
231
  Benign
 
97
  }
98
  ```
99
 
100
+ Every prompt sequence is 8,192 bp long and is wrapped in closed DNA tags, for example `<dna>...</dna>`. The variant is placed at the final base of the sequence context: `variant_index_0based = 8191`, equivalent to `variant_position_1based = 8192`.
101
 
102
  The `all_tasks` config has 6,000 task rows but 4,000 unique variant keys. The `binary` and `clinvar_levels` configs are two views of the same 2,000 clinical-classification variants; `pathogenic_pairwise` contributes 2,000 additional pathogenic or likely pathogenic variants.
103
 
 
214
 
215
  ### `binary`
216
 
217
+ The prompt states the mutation location in natural language and shows an 8,192 bp DNA sequence window containing the alternate allele at the final base of the context. For example, it tells the model that the variant is at position 8,192 using 1-based indexing, and that the reference allele is changed to the alternate allele at that position. The model is asked to answer with exactly one option:
218
 
219
  ```text
220
  benign or likely benign
 
225
 
226
  ### `clinvar_levels`
227
 
228
+ This task uses the same sequence prompt style as `binary`, including the natural-language mutation location sentence, but preserves the retained raw ClinVar label. Allowed answers are:
229
 
230
  ```text
231
  Benign
all_tasks/train-00000-of-00001.jsonl CHANGED
@@ -1,3 +1,3 @@
1
  version https://git-lfs.github.com/spec/v1
2
- oid sha256:e96535d15744930b81154e8d7c3ee96aff217f9c0a160070b7a9272739d3fe82
3
- size 210851553
 
1
  version https://git-lfs.github.com/spec/v1
2
+ oid sha256:9995e04aa33b9163c8894faabc97ac226b60409d5a4b6e8dfd5003ca1b2f428d
3
+ size 212099553
binary/train-00000-of-00001.jsonl CHANGED
@@ -1,3 +1,3 @@
1
  version https://git-lfs.github.com/spec/v1
2
- oid sha256:0192484cf7a48e60291f8a53d0160f61a67f393bf45d2f957e4fb72078f4ba71
3
- size 54112557
 
1
  version https://git-lfs.github.com/spec/v1
2
+ oid sha256:6630bdc1a94cc6a6769c73de779001a0cef6a6d86b3aa3ca05d596c96b254330
3
+ size 54700557
clinvar_levels/train-00000-of-00001.jsonl CHANGED
@@ -1,3 +1,3 @@
1
  version https://git-lfs.github.com/spec/v1
2
- oid sha256:a311857606a5e035bb4edb650307f4c3f9a62c39196be2973f350a396dd7fab1
3
- size 54448553
 
1
  version https://git-lfs.github.com/spec/v1
2
+ oid sha256:637a086379095a8ed0da6b9eada1f05dfcd1024629245e0e17f106bd77401a27
3
+ size 55036553
pathogenic_pairwise/train-00000-of-00001.jsonl CHANGED
@@ -1,3 +1,3 @@
1
  version https://git-lfs.github.com/spec/v1
2
- oid sha256:ad6a2ea8543d0a52c3798fe311da9914373150285f450ae515028bfd4f3b4233
3
- size 102290443
 
1
  version https://git-lfs.github.com/spec/v1
2
+ oid sha256:cea36c57277b45d08c9e5e822742cd8f19521613c345f9224282b6683c436d2f
3
+ size 102362443