Update README.md

README.md

@@ -1,8 +1,8 @@
-# SNOOPPI
+# SNOOPPI: Sequence-Normalized Database of On- and Off-Target Protein-Protein Interactions
 
-SNOOPPI is a curated protein–protein interaction dataset containing positive, negative, and unknown interaction annotations.
-
-The dataset preserves protein sequences, identifiers, species information, PSI-MI interaction terms, experimental evidence, publications, feature relationships, and annotation provenance where available.
+SNOOPPI is a curated protein–protein interaction (PPI) dataset containing positive, negative, and unknown interaction annotations. 
+  * SNOOPPI is *sequence-indexed*, meaning one unique SNOOPPI PPI or non-PPI indicates a unique combination of protein sequences.
+  * The dataset preserves protein sequences, identifiers, species information, PSI-MI interaction terms, experimental evidence, publications, and feature relationships where available.
 
 ## Dataset splits
 
@@ -12,7 +12,7 @@ SNOOPPI is distributed in three splits:
 | ---------- | ------------------------------------------------------------------------------------------------------------------------------------------- |
 | `positive` | Protein pairs retained as positive interactions under the SNOOPPI annotation criteria                                                       |
 | `negative` | Protein pairs retained as negative interactions under the SNOOPPI annotation criteria                                                       |
-| `unknown`  | Protein pairs present in the source interaction records but not assigned a definitive positive or negative label under the SNOOPPI criteria |
+| `unknown`  | Protein pairs present in IntAct's source interaction records but not assigned a definitive positive or negative label under the SNOOPPI criteria |
 
 The `unknown` split should not automatically be interpreted as a negative or as a set of experimentally tested non-interactions. These entries represent interactions for which the available evidence was insufficient, conflicting, or otherwise unresolved under the annotation framework.